A High-Frequency Regulatory Polymorphism in the p53 Pathway Accelerates Tumor Development

Post, Sean M., Quintás-Cardama, Alfonso, Pant, Vinod, Iwakuma, Tomoo, Hamir, Amir, Jackson, James G., Maccio, Daniela R., Bond, Gareth L., Johnson, David G., Levine, Arnold J., Lozano, Guillermina·2010·Cancer Cell
DOI 10.1016/j.ccr.2010.07.010

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  5. Re: Murine double minute 2 promoter SNP309 polymorphism and prostate cancer risk: a meta‐analysis
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  6. Author response: Multi-species, multi-transcription factor binding highlights conserved control of tissue-specific biological pathways
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  8. SNPing Away at Cancer
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  9. LOODUS- JA TEHNOLOOGIATEADUSKOND MOLEKULAAR- JA RAKUBIOLOOGIA INSTITUUT
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  10. IN VIVO SIGNIFICANCE OF THE MDM4 AND P73 INTERACTION DURING DEVELOPMENT AND TUMORIGENESIS
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  11. Candidate Molecules as Tumor Suppressor for Human Uterine Mesenchymal Tumor
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  14. Exploring Chromatin-bound MDM2 Functions in Compromised Transcriptional Regulation of p53 Target Genes
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  15. In Vivo Discoveries in MDM2-Mediated p53 Regulation
    Nicole R. Tackmann · 2019 · Carolina Digital Repository (University of North Carolina at Chapel Hill)
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    Roxana Schaab · 2020
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  18. Characterization of synthetic lethality between Mdm2 overexpression and genotoxic agents and identification of a novel function of the Mdmx oncogene in DNA repair
    Alexia M. Carrillo · 2014
  19. The MDM2 SNP309 differentially impacts cardiorespiratory fitness in young healthy women and men
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    Joy M. McDaniel, Rhiannon L. Morrissey, Gilda P. Chau, Xiaoping Su, Zach von Ruff, Anil Korkut, Vidhi Chandra, Lei Huo, Adel K. El‐Naggar, Guillermina Lozano · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
  21. Implication de la voie p53 dans les syndromes d'insuffisance médullaire
    Romane Durand · 2020 · theses.fr (ABES)
  22. Epigenetic modulation of prostate cancer disparities in men with African ancestry
    Jenna Craddock, Vanessa M. Hayes · 2026 · Nature Reviews Urology
  23. Association of MDM2 rs2279744 and rs937282 polymorphisms with breast cancer susceptibility and circulating MDM2 and p53 levels in Bangladeshi women: A case-control study
    Mahim Hassan Chowdhury, Farzana Islam, Adiba Ayesha Khan, Md. Ayman Siddique, Nushaiba Binte Hasan, Mahinul Islam Samrat, Mehrin Haque Tanisha, Jarin Tasnim, Samiha Mahjabin, Md. Nazmul Islam et al. · 2026 · PLoS ONE
  24. BindingDB Entry 50020573: Discovery of JN122, a Spiroindoline-Containing Molecule that Inhibits MDM2/p53 Protein-Protein Interaction and Exerts Robust In Vivo Antitumor Efficacy.
    BindingDB · 2024 · UC San Diego