Cell of Origin of Small Cell Lung Cancer: Inactivation of Trp53 and Rb1 in Distinct Cell Types of Adult Mouse Lung
Sutherland, Kate D., Proost, Natalie, Brouns, Inge, Adriaensen, Dirk, Song, Ji-Ying, Berns, Anton·2011·Cancer Cell
Cited by (538)
Items 101–200 of 538
- Neuronal activity-dependent mechanisms of small cell lung cancer pathogenesisSolomiia Savchuk, Kaylee M. Gentry, Wengang Wang, Elana Carleton, Carlos Alberto Oliveira de Biagi, Karan D. Luthria, Belgin Yalçın, Lijun Ni, Hannah C Farnsworth, Rachel A. Davis et al. · 2025 · Nature
- New molecular classification of large cell neuroendocrine carcinoma and small cell lung carcinoma with potential therapeutic impactsSylvie Lantuéjoul, Lynnette Fernandez‐Cuesta, Francesca Damiola, Nicolas Girard, Anne Mc Leer · 2020 · Translational Lung Cancer Research
- LUBAC determines chemotherapy resistance in squamous cell lung cancerE. Josue Ruiz, Markus E. Diefenbacher, Jessica Kristine Nelson, Rocı́o Sancho, Fabio Pucci, Atanu Chakraborty, Paula Moreno, Alessandro Annibaldi, Gianmaria Liccardi, Vesela Encheva et al. · 2019 · The Journal of Experimental Medicine
- Future Options of Molecular-Targeted Therapy in Small Cell Lung CancerArik Bernard Schulze, Georg Evers, Andrea Kerkhoff, Michael Möhr, Christoph Schliemann, Wolfgang E. Berdel, Lars Henning Schmidt · 2019 · Cancers
- Current knowledge of small cell lung cancer transformation from non-small cell lung cancerGiuseppe Giaccone, Yongfeng He · 2023 · Seminars in Cancer Biology
- Circulating tumor cells and CDX models as a tool for preclinical drug developmentAlice Lallo, Maximilian W. Schenk, Kristopher K. Frese, Fiona Helen Blackhall, Caroline Dive · 2017 · Translational Lung Cancer Research
- Co-expression network analysis identifies Spleen Tyrosine Kinase (SYK) as a candidate oncogenic driver in a subset of small-cell lung cancerAkshata R. Udyavar, Megan D. Hoeksema, Jonathan E Clark, Yong Zou, Zuojian Tang, Zhiguo Li, Ming Li, Heidi Chen, Alexander Statnikov, Yu Shyr et al. · 2013 · BMC Systems Biology
- FoxA1 and FoxA2 drive gastric differentiation and suppress squamous identity in NKX2-1-negative lung cancerSoledad A. Camolotto, Shrivatsav Pattabiraman, Timothy L. Mosbruger, Alex D. Jones, Veronika K Belova, Grace Orstad, Mitchell Streiff, Lydia Salmond, Chris Stubben, Klaus H. Kaestner et al. · 2018 · eLife
- Novel Hybrid Phenotype Revealed in Small Cell Lung Cancer by a Transcription Factor Network Model That Can Explain Tumor HeterogeneityAkshata R. Udyavar, David J. Wooten, Megan Hoeksema, Mukesh Bansal, Andrea Califano, Lourdes Estrada, Santiago D. Schnell, Jonathan Michael Irish, Pierre P. Massion, Vito Quaranta · 2016 · Cancer Research
- Lung Stem and Progenitor Cells in Tissue Homeostasis and DiseaseKristen Tropea Leeman, Christine F. Brainson, Carla F. Kim · 2014 · Current topics in developmental biology/Current Topics in Developmental Biology
- Novel Transcriptional Targets of the SRY-HMG Box Transcription Factor SOX4 Link Its Expression to the Development of Small Cell Lung CancerSandra D. Castillo, Ander Matheu, Niccolò Mariani, Julián Carretero, Fernando López‐Ríos, Robin Howard Lovell-Badge, Montse Sánchez‐Céspedes · 2011 · Cancer Research
- Functional synapses between neurons and small cell lung cancerVignesh Sakthivelu, Anna Schmitt, Franka Odenthal, Kristiano Ndoci, Marian Touet, Ali Shaib, Abdulla W. Chihab, Gulzar A. Wani, Pascal Nieper, Griffin G. Hartmann et al. · 2025 · Nature
- RETRACTED ARTICLE: Suppression of inflammation and acute lung injury by Miz1 via repression of C/EBP-δHanh Chi Do-Umehara, Cong Chen, Daniela Urich, Liang Zhou, Ju Qiu, Samuel Jang, Alia D Zander, Margaret A Baker, Martin Eilers, Peter H. S. Sporn et al. · 2013 · Nature Immunology · Retracted
- Understanding Lineage Plasticity as a Path to Targeted Therapy Failure in EGFR-Mutant Non-small Cell Lung CancerTatiana Shaurova, Letian Zhang, David W. Goodrich, Pamela A. Hershberger · 2020 · Frontiers in Genetics
- Harnessing Natural Killer Immunity in Metastatic SCLCSarah A. Best, Jonas B. Hess, Fernando Souza-Fonseca-Guimarães, Joseph Cursons, Ariena J. Kersbergen, Xueyi Dong, Jai Rautela, Stephanie R. Hyslop, Matthew E. Ritchie, Melissa J. Davis et al. · 2020 · Journal of Thoracic Oncology
- Advanced small cell lung cancer (SCLC): new challenges and new expectationsNikolaos Tsoukalas, Eleni Aravantinou-Fatorou, Panagiotis Baxevanos, Maria Tolia, Konstantinos Tsapakidis, Michail Galanopoulos, Michail Liontos, George Kyrgias · 2018 · Annals of Translational Medicine
- Lamin B1 loss promotes lung cancer development and metastasis by epigenetic derepression of RETYanhan Jia, Joaquim S. L. Vong, Alina Asafova, Boyan K. Garvalov, Luca Caputo, Julio Cordero, Anshu Singh, Thomas Boettger, Stefan Günther, Ludger Fink et al. · 2019 · The Journal of Experimental Medicine
- Combined SCLC Clinical and Pathologic CharacteristicsShahab Babakoohi, Pingfu Fu, Michael Yang, Philip Aaron Linden, Afshin Dowlati · 2012 · Clinical Lung Cancer
- Small cell lung cancer: Subtypes and therapeutic implicationsWalter Wang, Alyssa Shulman, Joseph M. Amann, David Paul Carbone, Philip N. Tsichlis · 2022 · Seminars in Cancer Biology
- MAX functions as a tumor suppressor and rewires metabolism in small cell lung cancerA. Augert, Haritha Mathsyaraja, A. Ibrahim, B. Freie, Michael Geuenich, Pei-Feng Cheng, Sydney P. Alibeckoff, N. Wu, J. Hiatt, Ryan S. Basom et al. · 2020 · Cancer Cell
- NFIB overexpression cooperates with Rb/p53 deletion to promote small cell lung cancerNan Wu, Deshui Jia, Ali H. Ibrahim, Cindy J. Bachurski, Richard M. Gronostajski, David P MacPherson · 2016 · Oncotarget
- Killing SCLC: insights into how to target a shapeshifting tumorKate D. Sutherland, Abbie S. Ireland, Trudy G. Oliver · 2022 · Genes & Development
- The a“MAZE”ing World of Lung-Specific Transgenic MiceEmma L. Rawlins, Anne‐Karina T. Perl · 2011 · American Journal of Respiratory Cell and Molecular Biology
- Cells of origin for cancer: an updated view from prostate cancerL. Xin · 2012 · Oncogene
- Mechanisms of acquired resistance to EGFR-tyrosine kinase inhibitor in Korean patients with lung cancerWonjun Ji, Chang‐Min Choi, Jin Kyung Rho, Se Jin Jang, Young Soo Park, Sung‐Min Chun, Woo Sung Kim, Jung‐Shin Lee, Sang‐We Kim, Dae Ho Lee et al. · 2013 · BMC Cancer
- Dkk3 dependent transcriptional regulation controls age related skeletal muscle atrophyYin, Jie, Yang, Lele, Xie, Yangli, Liu, Yan, Li, Sheng, Yang, Wenjun, Xu, Bo, Ji, Hongbin, Ding, Lianghua, Wang, Kun et al. · 2018 · Nature Communications
- Single-Cell Analysis of Circulating Tumor Cells: Why Heterogeneity MattersSu Bin Lim, Chwee Teck Lim, Wan‐Teck Lim · 2019 · Cancers
- Evolution of the hypoxia-sensitive cells involved in amniote respiratory reflexesDorit Hockman, Alan J. Burns, Gerhard Schlosser, Keith P. Gates, Benjamin Jevans, Alessandro Mongera, Shannon Fisher, Gökhan Ünlü, Ela W. Knapik, Charles K. Kaufman et al. · 2017 · eLife
- Cell of origin of lung cancerMark W. Onaitis, Jennifer M. Hanna · 2013 · Journal of Carcinogenesis
- ASCL1 represses a SOX9 + neural crest stem-like state in small cell lung cancerRachelle R. Olsen, Abbie S. Ireland, David W. Kastner, Sarah M. Groves, Kyle B. Spainhower, Karine Pozo, Demetra P. Kelenis, Christopher P. Whitney, Matthew R. Guthrie, Sarah J. Wait et al. · 2021 · Genes & Development
- Consider the lung as a sensory organ: A tip from pulmonary neuroendocrine cellsAnkur Garg, Pengfei Sui, Jamie M. Verheyden, Lisa R. Young, Xin Sun · 2019 · Current topics in developmental biology/Current Topics in Developmental Biology
- Challenges of small cell lung cancer heterogeneity and phenotypic plasticityKathryn Simpson, Dominic G. Rothwell, Fiona Helen Blackhall, Caroline Dive · 2025 · Nature reviews. Cancer
- Lineage factors and differentiation states in lung cancer progressionWilliam K.C. Cheung, Don X. Nguyen · 2015 · Oncogene
- Less Is More: Rare Pulmonary Neuroendocrine Cells Function as Critical Sensors in LungJinhao Xu, Haoze Vincent Yu, Xin Sun · 2020 · Developmental Cell
- Combined Small Cell Carcinoma of the Lung: Is It a Single Entity?Xiaoliang Zhao, Justine N. McCutcheon, Bhaskar Kallakury, Joeffrey J. Chahine, Drew W. Pratt, Mark A. Raffeld, Yulong Chen, Changli Wang, Giuseppe Giaccone · 2017 · Journal of Thoracic Oncology
- Archetype tasks link intratumoral heterogeneity to plasticity and cancer hallmarks in small cell lung cancerSarah M. Groves, Geena V. Ildefonso, Caitlin O. McAtee, Patricia Midori Murobushi Ozawa, Abbie S. Ireland, Philip E. Stauffer, Perry T. Wasdin, Xiaomeng Huang, Yi Qiao, Jing Shan Lim et al. · 2022 · Cell Systems
- Diversity of Epithelial Stem Cell Types in Adult LungFeng Li, Jinxi He, Jun Wei, William Chi Shing Cho, Xiaoming Liu · 2015 · Stem Cells International
- Organoid models in lung regeneration and cancerJianhai Wang, Xianglu Li, Huaiyong Chen · 2020 · Cancer Letters
- Stemness and inducing differentiation of small cell lung cancer NCI-H446 cellsZhihui Zhang, Yifei Zhou, Hui Qian, Genbao Shao, Xiaodong Lü, Q Chen, Xiaochun Sun, D Chen, R Yin, Hua Ling Zhu et al. · 2013 · Cell Death and Disease
- Mechanisms of resistance to EGFR targeted therapiesGorjan Hrustanovic, Bianca J. Lee, Trever Grant Bivona · 2013 · Cancer Biology & Therapy
- Cell of Origin Links Histotype Spectrum to Immune Microenvironment Diversity in Non-small-Cell Lung Cancer Driven by Mutant Kras and Loss of Lkb1Ashwini Sakrepatna Nagaraj, Jenni Lahtela, Annabrita Hemmes, Teijo S. Pellinen, Sami Blom, Jennifer R. Devlin, Kaisa Salmenkivi, Olli Kallioniemi, Mikko Ilari Mäyränpää, Katja Maria Närhi et al. · 2017 · Cell Reports
- Resistance to EGFR inhibitors in non-small cell lung cancer: Clinical management and future perspectivesChiara Tomasello, Cinzia Baldessari, Martina Napolitano, Giulia Orsi, Giulia Grizzi, Federica Bertolini, Fausto Barbieri, Stefano Cascinu · 2018 · Critical Reviews in Oncology/Hematology
- Tumor Heterogeneity Underlies Differential Cisplatin Sensitivity in Mouse Models of Small-Cell Lung CancerFranziska Böttger, Ekaterina A. Semenova, Ji‐Ying Song, Giustina Ferone, Jan van der Vliet, Miranda Cozijnsen, Rajith Bhaskaran, Lorenzo Bombardelli, Sander R. Piersma, Thang V. Pham et al. · 2019 · Cell Reports
- Advances in Small-Cell Lung Cancer (SCLC) Translational ResearchBenjamin Jacob Drapkin, Charles M. Rudin · 2020 · Cold Spring Harbor Perspectives in Medicine
- Transformation to Small Cell Lung Cancer of Pulmonary Adenocarcinoma: Clinicopathologic Analysis of Six CasesSoomin Ahn, Soo Hyun Hwang, Joungho Han, Yoon‐La Choi, Se‐Hoon Lee, Jin Seok Ahn, Keunchil Park, Myung‐Ju Ahn, Woong‐Yang Park · 2016 · Journal of Pathology and Translational Medicine
- Circulating Tumor DNA Profiling in Small-Cell Lung Cancer Identifies Potentially Targetable AlterationsSiddhartha H. K. Devarakonda, Sumithra Sankararaman, Brett H. Herzog, Kathryn Ann Gold, Saiama Naheed Waqar, Jeffrey P. Ward, Victoria M. Raymond, Richard Burnham Lanman, Aadel A. Chaudhuri, Taofeek Kunle Owonikoko et al. · 2019 · Clinical Cancer Research
- Sphere Culture of Murine Lung Cancer Cell Lines Are Enriched with Cancer Initiating CellsBrian J. Morrison, Jason C. Steel, John Charles Morris · 2012 · PLoS ONE
- Intrinsic electrical activity drives small-cell lung cancer progressionPaola Peinado, Marco Stazi, Claudio Ballabio, Michael-Bogdan Margineanu, Zhaoqi Li, Caterina I. Colón, Min‐Shu Hsieh, Shreoshi Pal Choudhuri, Victor Stastny, Seth Hamilton et al. · 2025 · Nature
- Neuroendocrinology of the lung revealed by single-cell RNA sequencingChristin S. Kuo, Spyros Darmanis, Alex Diaz de Arce, Yin Liu, Nicole Almanzar, Ting-Hsuan Wu, Stephen R. Quake, Mark A. Krasnow · 2022 · eLife
- Lung cancer stem cells: Molecular features and therapeutic targetsSandeep Singh, Srikumar Chellappan · 2013 · Molecular Aspects of Medicine
- Effective growth-suppressive activity of maternal embryonic leucine-zipper kinase (MELK) inhibitor against small cell lung cancerHiroyuki Inoue, Taigo Kato, Sope Omowale Olugbile, Kenji Tamura, Suyoun Chung, Takashi Miyamoto, Yo Matsuo, Ravi Salgia, Yusuke Nakamura, Jae-Hyun Park · 2016 · Oncotarget
- ASCL1, NKX2-1, and PROX1 co-regulate subtype-specific genes in small-cell lung cancerKarine Pozo, Rahul Krishna Kollipara, Demetra P. Kelenis, Kathia E. Rodarte, Morgan S. Ullrich, Xiaoyang Zhang, John Dorrance Minna, Jane E. B. Johnson · 2021 · iScience
- The Resistance to EGFR-TKIs in Non-Small Cell Lung Cancer: From Molecular Mechanisms to Clinical Application of New Therapeutic StrategiesCarmelo Laface, Felicia Maria Maselli, Anna Natalizia Santoro, Maria Laura Iaia, Francesca Ambrogio, Marigia Laterza, Chiara Guarini, Pierluigi De Santis, Martina Perrone, Palma Fedele · 2023 · Pharmaceutics
- Genetically-engineered mouse models of small cell lung cancer: the next generationMatthew G. Oser, David P MacPherson, Trudy G. Oliver, Julien Sage, Kwon-Sik Park · 2024 · Oncogene
- Small cells – big issues: biological implications and preclinical advancements in small cell lung cancerAnna Solta, Büsra Ernhofer, Kristiina Boettiger, Zsolt Megyesfalvi, Simon Heeke, Mir Alireza Hoda, Christian Lang, Clemens Aigner, Fred R. Hirsch, Karin Schelch et al. · 2024 · Molecular Cancer
- “Keaping” a lid on lung cancer: the Keap1-Nrf2 pathwaySarah A. Best, Kate D. Sutherland · 2018 · Cell Cycle
- FGFR1 Oncogenic Activation Reveals an Alternative Cell of Origin of SCLC in Rb1/p53 MiceGiustina Ferone, Ji‐Ying Song, Oscar Krijgsman, Jan van der Vliet, Miranda Cozijnsen, Ekaterina A. Semenova, David J. Adams, Daniel S. Peeper, Anton J. M. Berns · 2020 · Cell Reports
- Human pluripotent stem cell‐derived lung organoids: Potential applications in development and disease modelingLu Tian, Jinghui Gao, Irving M. Garcia, Huanhuan Joyce Chen, Alessandra Castaldi, Ya‐Wen Chen · 2020 · Wiley Interdisciplinary Reviews Developmental Biology
- Merkel Cell Polyomavirus‒Negative Merkel Cell Carcinoma Originating from In Situ Squamous Cell Carcinoma: A Keratinocytic Tumor with Neuroendocrine DifferentiationThibault Kervarrec, Silke Appenzeller, Mahtab Samimi, Bhavishya Sarma, Eva‐Maria Sarosi, Patricia Berthon, Y. Le Corre, Ewa Hainaut‐Wierzbicka, Astrid Blom, N. Bénéton et al. · 2021 · Journal of Investigative Dermatology
- YAP silencing by RB1 mutation is essential for small-cell lung cancer metastasisZhengMing Wu, Junhui Su, Fu-long Li, Tao Chen, Jaimie Mayner, Adam Jeffrey Engler, Shenghong Ma, Qingquan Li, Kun‐Liang Guan · 2023 · Nature Communications
- Signal control through Raf: in sickness and in healthJihan K. Osborne, Elma Zaganjor, Melanie H. Cobb · 2011 · Cell Research
- Lung Basal Stem Cells Rapidly Repair DNA Damage Using the Error-Prone Nonhomologous End-Joining PathwayClare E. Weeden, Yunshun Chen, Stephen B. Ma, Yifang Hu, Georg Ramm, Kate D. Sutherland, Gordon K. Smyth, Marie-Liesse Asselin-Labat · 2017 · PLoS Biology
- Small cell lung cancer profiling: an updated synthesis of subtypes, vulnerabilities, and plasticityEsther Redín, Àlvaro Quintanal-Villalonga, Charles M. Rudin · 2024 · Trends in cancer
- Targeting CREB Pathway Suppresses Small Cell Lung CancerYifeng Xia, Cheng Zhan, Mingxiang Feng, Mathias Leblanc, Eugene Ke, Narayana Yeddula, Inder M. Verma · 2018 · Molecular Cancer Research
- Multi-omics profiling of primary small cell carcinoma of the esophagus reveals RB1 disruption and additional molecular subtypesRenda Li, Zhenlin Yang, Fei Shao, Hong Sheng Cheng, Yaru Wen, Sijin Sun, Wei Guo, Zitong Li, Fan Zhang, Liyan Xue et al. · 2021 · Nature Communications
- Clonal Evolution and Epithelial Plasticity in the Emergence of AR-Independent Prostate CarcinomaSara Laudato, Ana M. Aparicio, Filippo G. Giancotti · 2019 · Trends in cancer
- Differential development of large-cell neuroendocrine or small-cell lung carcinoma upon inactivation of 4 tumor suppressor genesSara Lázaro, Míriam Pérez-Crespo, Corina Lorz, Alejandra Bernardini, Marta Oteo, Ana B. Enguita, Eduardo Romero, Pilar Hernández, Laura Tomás, Miguel Ángel Morcillo et al. · 2019 · Proceedings of the National Academy of Sciences
- Histological transformation in lung adenocarcinoma: Insights of mechanisms and therapeutic windowsNuopei Tan, Yan Li, Jianming Ying, Wanqing Chen · 2024 · Journal of Translational Internal Medicine
- Combined deletion of Bap1 , Nf2 , and Cdkn2ab causes rapid onset of malignant mesothelioma in miceJitendra Badhai, Gaurav Kumar Pandey, Ji‐Ying Song, Oscar Krijgsman, Rajith Bhaskaran, Gayathri Chandrasekaran, Min-chul Kwon, Lorenzo Bombardelli, Kim Monkhorst, Cristoforo Grasso et al. · 2020 · The Journal of Experimental Medicine
- Basal cell of origin resolves neuroendocrine–tuft lineage plasticity in cancerAbbie S. Ireland, Daniel A Xie, Sarah B. Hawgood, Margaret W. Barbier, Lisa Y. Zuo, Benjamin E Hanna, Scarlett Lucas-Randolph, Darren R. Tyson, Benjamin L. Witt, Ramaswamy Govindan et al. · 2025 · Nature
- Lineage Tracing of Mammary Epithelial Cells Using Cell-Type-Specific Cre-Expressing AdenovirusesLuwei Tao, Maaike P.A. van Bragt, Elizabeth D. Laudadio, Zhe Li · 2014 · Stem Cell Reports
- Adult lung stem cells and their contribution to lung tumourigenesisMarie-Liesse Asselin-Labat, Caitlin E. Filby · 2012 · Open Biology
- Biomarkers for small cell lung cancer: Neuroendocrine, epithelial and circulating tumour cellsRachel Stovold, Fiona Helen Blackhall, Suzanne L. Meredith, Jianmei Hou, Caroline Dive, Anne E. White · 2011 · Lung Cancer
- Cellular Mechanisms Underlying Intertumoral HeterogeneityKate D. Sutherland, Jane E. Visvader · 2015 · Trends in cancer
- MEN1 deficiency leads to neuroendocrine differentiation of lung cancer and disrupts the DNA damage responseHuan Qiu, Bangming Jin, Zhanfeng Wang, Bin Xu, Qi‐Fan Zheng, Li Zhang, Ling-Yu Zhu, Shuang Shi, Jun-Bo Yuan, Xiao Lin et al. · 2020 · Nature Communications
- Small Cell Lung Cancer Transformation as a Mechanism of Resistance to PD-1 Therapy in KRAS-Mutant Lung Adenocarcinoma: A Report of Two CasesWade Thomas Iams, Kathryn Eby Beckermann, Karinna Almodovar, Jennifer Hernandez, Cindy L. Vnencak‐Jones, Lee P. Lim, Christopher K. Raymond, Leora Horn, Christine Marie Lovly · 2018 · Journal of Thoracic Oncology
- Rlf–Mycl Gene Fusion Drives Tumorigenesis and Metastasis in a Mouse Model of Small Cell Lung CancerMetamia Ciampricotti, Triantafyllia Karakousi, Allison L. Richards, Àlvaro Quintanal-Villalonga, Angeliki Karatza, Rebecca Caeser, Emily A. Costa, Viola Allaj, Parvathy Manoj, Kyle B. Spainhower et al. · 2021 · Cancer Discovery
- Comprehensive analysis of treatment modes and clinical outcomes of small cell lung cancer transformed from epidermal growth factor receptor mutant lung adenocarcinomaShouzheng Wang, Tongji Xie, Xuezhi Hao, Yan Wang, Xingsheng Hu, Lin Wang, Yan Li, Junling Li, Puyuan Xing · 2021 · Thoracic Cancer
- Promoters of ASCL1‐ and NEUROD1‐dependent genes are specific targets of lurbinectedin in SCLC cellsFederico Costanzo, Marta Martínez, Gema Santamaría Núñez, Juan Ignacio Díaz‐Hernandéz, Carlos Mario Genes Robles, Javier Díez Pérez, Emmanuel Compe, Roméo Ricci, Tsai‐Kun Li, Frédéric Coin et al. · 2022 · EMBO Molecular Medicine
- Poly(β-amino ester) Nanoparticle Delivery of TP53 Has Activity against Small Cell Lung Cancer In Vitro and In VivoChandrashekhar D. Kamat, Ron B. Shmueli, Nick Connis, Charles M. Rudin, Jordan J. Green, Christine L. Hann · 2013 · Molecular Cancer Therapeutics
- Cholinergic Targets in Lung CancerEliot R. Spindel · 2016 · Current Pharmaceutical Design
- Immunogenomic cancer evolution: A framework to understand cancer immunosuppressionShogo Kumagai, Yusaku Momoi, Hiroyoshi Nishikawa · 2025 · Science Immunology
- Mutationally Activated PIK3CAH1047R Cooperates with BRAFV600E to Promote Lung Cancer ProgressionChristy L. Trejo, Shon Green, Victoria L. Marsh, Eric Andrew Collisson, Gioia Iezza, Wayne Allen Phillips, Martin McMahon · 2013 · Cancer Research
- Emerging Biomarkers and the Changing Landscape of Small Cell Lung CancerAnna Keogh, Stephen P. Finn, Teodora Radonic · 2022 · Cancers
- Olfactory neuroblastoma mimics molecular heterogeneity and lineage trajectories of small-cell lung cancerJohn B. Finlay, Abbie S. Ireland, Sarah B. Hawgood, Tony Reyes, Tiffany Ko, Rachelle R. Olsen, Ralph Abi Hachem, David Woojin Jang, Diana Bell, Joseph Minhow Chan et al. · 2024 · Cancer Cell
- Upregulation of FGF9 in Lung Adenocarcinoma Transdifferentiation to Small Cell Lung CancerKota Ishioka, Hiroyuki Yasuda, Junko Hamamoto, Hideki Terai, Katsura Emoto, Tae Jung Kim, Shigemichi Hirose, Takashi Kamatani, Sachiyo Mimaki, Daisuke Arai et al. · 2021 · Cancer Research
- Recent advances in the molecular landscape of lung neuroendocrine tumorsGiuseppe Pelosi, Fabrizio Bianchi, Paul M Hofman, Linda Pattini, Philipp Ströbel, Fiorella Calabrese, Salma Naheed, Chloe Holden, Judith Cave, Hanibal Bohnenberger et al. · 2019 · Expert Review of Molecular Diagnostics
- Notch Transduction in Non-Small Cell Lung CancerAmnah Sharif, Ann Shaji, May Chammaa, Eileen Pawlik, Rodrigo Fernandez‐Valdivia · 2020 · International Journal of Molecular Sciences
- NeuroD1 regulation of migration accompanies the differential sensitivity of neuroendocrine carcinomas to TrkB inhibitionJihan K. Osborne, Jill E. Larsen, Joshua X. Gonzales, David S. Shames, Mitsuo Sato, Ignacio Ivan Wistuba, Luc Girard, John Dorrance Minna, Melanie H. Cobb · 2013 · Oncogenesis
- Distinct genetic alterations in small cell carcinoma from different anatomic sitesXiaoyong Zheng, Delong Liu, John T. Fallon, Minghao Zhong · 2015 · Experimental Hematology and Oncology
- SnapShot: Lung Cancer ModelsAnna F. Farago, Eric L. Snyder, Tyler Jacks · 2012 · Cell
- Whole exome sequencing (WES) analysis of transformed small cell lung cancer (SCLC) from lung adenocarcinoma (LUAD)Tongji Xie, Yan Li, Jianming Ying, Weijing Cai, Junling Li, Kye Young Lee, Biagio Ricciuti, Jose M. Pacheco, Puyuan Xing · 2020 · Translational Lung Cancer Research
- Transcriptional deregulation underlying the pathogenesis of small cell lung cancerDong Wook Kim, Keun‐Cheol Kim, Kee‐Beom Kim, Colin T. Dunn, Kwon-Sik Park · 2018 · Translational Lung Cancer Research
- Targeting Menin disrupts the KMT2A/B and polycomb balance to paradoxically activate bivalent genesChristina E. Sparbier, Andrea Gillespie, Juliana Gomez, Nishi Kumari, Ali Motazedian, Kah Lok Chan, Charles C. Bell, Omer Gilan, Yih-Chih Chan, Sarah Popp et al. · 2023 · Nature Cell Biology
- Lung Cancer Stem Cell: Fancy Conceptual Model of Tumor Biology or Cornerstone of a Forthcoming Therapeutic Breakthrough?Tony Sourisseau, Khaled Aref Hassan, Ignacio Ivan Wistuba, Frederique Madeleine Penault-Llorca, Julien Adam, Éric Deutsch, Jean‐Charles Soria · 2013 · Journal of Thoracic Oncology
- TOPK (T‐ LAK cell‐originated protein kinase) inhibitor exhibits growth suppressive effect on small cell lung cancerJae‐Hyun Park, Hiroyuki Inoue, Taigo Kato, Makda Getachew Zewde, Takashi Miyamoto, Yo Matsuo, Ravi Salgia, Yusuke Nakamura · 2017 · Cancer Science
- SOX2 and Rb1 in esophageal small-cell carcinoma: their possible involvement in pathogenesisHirotaka Ishida, Atsuko Kasajima, Takashi Kamei, Tsuyoshi Miura, Naomi Oka, Samaneh Yazdani, Yohei Ozawa, Fumiyoshi Fujishima, Akira Sakurada, Yasuhiro Nakamura et al. · 2017 · Modern Pathology
- KIX domain determines a selective tumor-promoting role for EP300 and its vulnerability in small cell lung cancerKee‐Beom Kim, Ashish Kabra, Dong Wook Kim, Yongming Xue, Yuanjian Huang, Pei‐Chi Hou, Yunpeng Zhou, Leilani J. Miranda, Jae‐Il Park, Xiaobing Shi et al. · 2022 · Science Advances
- Current and future therapies for small cell lung carcinomaXiaoqian Zhai, Zhengkun Zhang, Yuxin Chen, Yan Wu, Cheng Zhen, Yu Liu, Yiyun Lin, Chong Chen · 2025 · Journal of Hematology & Oncology
- Context-Dependent Effects of Amplified MAPK Signaling during Lung Adenocarcinoma Initiation and ProgressionMichelle Cicchini, Elizabeth L. Buza, Kyra M. Sagal, A. Andrea Gudiel, Amy C. Durham, David M. Feldser · 2017 · Cell Reports