The glycolytic shift in fumarate-hydratase-deficient kidney cancer lowers AMPK levels, increases anabolic propensities and lowers cellular iron levels

Tong, Wing-Hang, Sourbier, Carole, Kovtunovych, Gennady, Jeong, Suh Young, Vira, Manish, Ghosh, Manik, Romero, Vladimir Valera, Sougrat, Rachid +10 more·2011·Cancer Cell

Cited by (213)

Items 101–200 of 213

  1. Cells Lacking the Fumarase Tumor Suppressor Are Protected from Apoptosis through a Hypoxia-Inducible Factor-Independent, AMPK-Dependent Mechanism
    Bardella, Chiara, Olivero, Martina, Lorenzato, Annalisa, Geuna, Massimo, Adam, Julie, O'Flaherty, Linda, Rustin, Pierre, Tomlinson, Ian, Pollard, Patrick J., Di Renzo, Maria Flavia · 2012 · Molecular and Cellular Biology
  2. A Deep Insight into Ferroptosis in Renal Disease: Facts and Perspectives
    Zhongyu Han, Yuanke Luo, Haoran Chen, Guochen Zhang, Luling You, Meiqi Zhang, Yumeng Lin, Yuan Lan, Shiyi Zhou · 2024 · Kidney Diseases
  3. Recent Advances in Metabolic Profiling and Imaging of Prostate Cancer
    Roopa Thapar, Mark Anton Titus · 2014 · Current Metabolomics
  4. Comprehensive genomic and phenotypic characterization of germline FH deletion in hereditary leiomyomatosis and renal cell carcinoma
    Cathy D. Vocke, Christopher J. Ricketts, Maria J. Merino, Ramaprasad Srinivasan, Adam R. Metwalli, Lindsay A. Middelton, James C. Peterson, Youfeng Yang, William Marston Linehan · 2017 · Genes Chromosomes and Cancer
  5. Deuterium Depletion Inhibits Cell Proliferation, RNA and Nuclear Membrane Turnover to Enhance Survival in Pancreatic Cancer
    László G. Boros, Ildikó Somlyai, B Kovács, László Géza Puskás, Lajos István Nagy, A László, Gyula Farkas, Gábor Somlyai · 2021 · Cancer Control
  6. Genomics of chromophobe renal cell carcinoma: implications from a rare tumor for pan-cancer studies
    K. Rathmell, Feng-Ju Chen, C. Creighton · 2015 · Oncoscience
  7. Hereditary leiomyomatosis and renal cell carcinoma syndrome associated uterine smooth muscle tumors: Bridging morphology and clinical screening
    Karuna Garg, Joseph T. Rabban · 2020 · Genes Chromosomes and Cancer
  8. Gene of the month: FH
    Roman E. Zyla, Anjelica Hodgson · 2021 · Journal of Clinical Pathology
  9. Genomic and metabolic characterization of a chromophobe renal cell carcinoma cell line model (UOK276)
    Youfeng Yang, Cathy D. Vocke, Christopher J. Ricketts, Darmood Wei, Hesed M. Padilla‐Nash, Martin Lang, Carole Sourbier, J. Keith Killian, Shawna L. Boyle, Robert Worrell et al. · 2017 · Genes Chromosomes and Cancer
  10. Genetic Alterations in Renal Cancers: Identification of The Mechanisms Underlying Cancer Initiation and Progression and of Therapeutic Targets
    Ugo Testa, Elvira Pelosi, Germana Castelli · 2020 · Medicines
  11. Leiomyoma with Bizarre Nuclei: a Study of 108 Cases Focusing on Clinicopathological Features, Morphology, and Fumarate Hydratase Alterations
    Mária Gregová, Jan Hojny, Kristýna Němejcová, Michaela Bártů, Michal Mára, Barbora Boudová, Ján Laco, Lukáš Krbal, Ivana Tichá, Pavel Dundr · 2019 · Pathology & Oncology Research
  12. UCP2 induces metabolic reprogramming to inhibit proliferation of cancer cells
    Pauline Estèves, Claire Pecqueur, Marie‐Clotilde Alves‐Guerra · 2014 · Molecular & Cellular Oncology
  13. IL-6 signaling accelerates iron overload by upregulating DMT1 in endothelial cells to promote aortic dissection
    Qiang Xie, Jianji Wang, Runqiao Li, Hao Liu, Yongliang Zhong, Qinfeng Xu, Yipeng Ge, Chengnan Li, Li‐Zhong Sun, Junming Zhu · 2024 · International Journal of Biological Sciences
  14. Curcumin Analog, HO‐3867, Induces Both Apoptosis and Ferroptosis via Multiple Mechanisms in NSCLC Cells with Wild‐Type p53
    Ling Wu, Guodong Xu, Ni Li, Linwen Zhu, Guofeng Shao · 2023 · Evidence-based Complementary and Alternative Medicine
  15. The Genetic Basis of Kidney Cancer: Implications for Management and Use of Targeted Therapeutic Approaches
    William Marston Linehan · 2012 · European Urology
  16. Cancer and the Kidney: The Growth of Onco-nephrology
    Mark Anthony Perazella, Jeffrey S. Berns, Mitchell Howard Rosner · 2013 · Advances in Chronic Kidney Disease
  17. Oncogenic TFE3 fusions drive OXPHOS and confer metabolic vulnerabilities in translocation renal cell carcinoma
    Jiao Li, Kaimeng Huang, Meha Thakur, Fiona McBride, Ananthan Sadagopan, Daniel S Gallant, Prateek Khanna, Yasmin Nabil Laimon, Bingchen Li, Razan Assaad Mohanna et al. · 2025 · Nature Metabolism
  18. MicroRNA-206 suppresses mesothelioma progression via the Ras signaling axis
    Anand Narayan Singh, Nathanael D. Pruett, Roma Pahwa, Arushi Mahajan, David S. Schrump, Chuong D. Hoang · 2021 · Molecular Therapy — Nucleic Acids
  19. AMP‐activated protein kinase couples 3‐bromopyruvate‐induced energy depletion to apoptosis via activation of FoxO3a and upregulation of proapoptotic Bcl‐2 proteins
    Çağrı Bodur, Bahriye Karakaş, Ahmet Can Timuçin, Tuğsan Tezil, Hüveyda Başağa · 2015 · Molecular Carcinogenesis
  20. AMPKα2 promotes tumor immune escape by inducing CD8+ T-cell exhaustion and CD4+ Treg cell formation in liver hepatocellular carcinoma
    Yan Ouyang, Yan Gu, Xinhai Zhang, Ya Huang, Xianpeng Wei, Fuzhou Tang, Shichao Zhang · 2024 · BMC Cancer
  21. Metabolic Syndrome Negatively Impacts the Outcome of Localized Renal Cell Carcinoma
    MAXIMILIAN CHRISTIAN KRIEGMAIR, Philipp C. Mandel, Štefan Porubský, Julia Dürr, Nina Huck, Philipp Nuhn, Daniel Pfalzgraf, Maurice Stephan Michel, Nina Wagener · 2017 · Hormones and Cancer
  22. Hereditary kidney cancer syndromes: Genetic disorders driven by alterations in metabolism and epigenome regulation
    Hisashi Hasumi, Masahiro Yao · 2018 · Cancer Science
  23. The Pleiotropic Effects of Fumarate: From Mitochondrial Respiration to Epigenetic Rewiring and DNA Repair Mechanisms
    Sebastiano Giallongo, Francesco Costa, Lucia Longhitano, Cesarina Giallongo, Jessica Ferrigno, Emanuela Tropea, Nunzio Vicario, Giovanni Li Volti, Rosalba Parenti, Ignazio Alberto Barbagallo et al. · 2023 · Metabolites
  24. Renal cell cancer: overview of the current therapeutic landscape
    Mustafa Erman, Mustafa Beneklı, Mert Başaran, Sevil E. Bavbek, Süleyman Buyukberber, Uğur Çoşkun, Gökhan Demir, Bülent Karabulut, Berna Çakmak Öksüzoğlu, Metin Özkan et al. · 2016 · Expert Review of Anticancer Therapy
  25. Complex role of HIF in cancer: the known, the unknown, and the unexpected
    Eric L. Huang, Patricia D.B. Tiburcio, Hyunsung Choi · 2014 · Hypoxia
  26. Nickel‐induced VEGF expression via regulation of Akt, ERK1/2, NFκB, and AMPK pathways in H460 cells
    Jui‐Chin Wang, Shih‐Yin Chen, Meilin Wang, Jiunn‐Liang Ko, Chieh‐Lin Wu, Ching‐Chung Chen, Hui‐Wen Lin, Yuan‐Yen Chang · 2019 · Environmental Toxicology
  27. Underexpression of tumour suppressor LKB1 in clear cell renal cell carcinoma is common and confers growth advantage in vitro and in vivo
    Wilhelmina Duivenvoorden, Laura K. Beatty, Šárka Lhoták, Brianne Hill, Isabella W.Y. Mak, Gregory A. Paulin, Daniel Gallino, Snežana Popović, Richard C. Austin, Jehonathan H. Pinthus · 2013 · British Journal of Cancer
  28. Fumarate hydratase as a therapeutic target in renal cancer
    Priyanka Kancherla, Michael Daneshvar, Rebecca Sager, Mehdi Mollapour, Gennady Bratslavsky · 2020 · Expert Opinion on Therapeutic Targets
  29. Five decades of urologic pathology: the accelerating expansion of knowledge in renal cell neoplasia
    Gregory T. MacLennan, Liang Cheng C · 2019 · Human Pathology
  30. Assessing Genomic Copy Number Alterations as Best Practice for Renal Cell Neoplasia: An Evidence-Based Review from the Cancer Genomics Consortium Workgroup
    Yajuan J. Liu, Jane Houldsworth, Rajyasree Emmadi, Lisa M. Dyer, Daynna J. Wolff · 2020 · Cancer Genetics
  31. New molecular targets in non clear renal cell carcinoma: An overview of ongoing clinical trials
    Chiara Ciccarese, Francesco Massari, Matteo Santoni, Daniel Yick Chin Heng, Valeria Sotte, Matteo Brunelli, Alessandro Conti, Liang Cheng C, Antonio Lopez-beltran B, Marina Scarpelli et al. · 2015 · Cancer Treatment Reviews
  32. A two-dimensional screen for AMPK substrates identifies tumor suppressor fumarate hydratase as a preferential AMPKα2 substrate
    Anna Klaus, Cécile Polge, Sarah Zorman, Yolanda Auchli, René Brunisholz, Uwe Schlattner · 2012 · Journal of Proteomics
  33. Functional genomics and metabolomics reveal the toxicological effects of cadmium in Mus musculus mice
    Miguel Ángel García-Sevillano, Nieves Abril, Ricardo Fernández-Cisnal, Tamara García‐Barrera, Carmen Pueyo, Juan López‐Barea, José Luis Gómez‐Ariza · 2015 · Metabolomics
  34. Deferoxamine Counteracts Cisplatin Resistance in A549 Lung Adenocarcinoma Cells by Increasing Vulnerability to Glutamine Deprivation-Induced Cell Death
    Wenjun Liu, Peng-yu Pan, Ye Sun, Jianbo Wang, Huan Zhou, Xin Xie, Zhiyuan Duan, Han-yu Dong, Wenna Chen, Li-de Zhang et al. · 2022 · Frontiers in Oncology
  35. Kidney tumors associated with germline mutations of FH and SDHB show a CpG island methylator phenotype (CIMP)
    Christopher J. Ricketts, J. Keith Killian, Cathy D. Vocke, Yonghong Wang, Maria J. Merino, Paul S. Meltzer, William Marston Linehan · 2022 · PLoS ONE
  36. Rewiring of RNA methylation by the oncometabolite fumarate in renal cell carcinoma
    Christina M. Fitzsimmons, Mariana D. Mandler, Judith C. Lunger, Dalen Chan, Siddhardha S. Maligireddy, Alexandra C Schmiechen, Supuni Thalalla Gamage, Courtney N. Link, Lisa M. Miller Jenkins, King C. Chan et al. · 2024 · NAR Cancer
  37. Metabolomics in renal cell carcinoma: From biomarker identification to pathomechanism insights
    Yuanyuan Chen, He-He Hu, Yanni Wang, Jingru Liu, Haijing Liu, Jianling Liu, Ying‐Yong Zhao · 2020 · Archives of Biochemistry and Biophysics
  38. Molecular Genetics of Renal Cell Carcinoma: A Narrative Review Focused on Clinical Relevance
    Braden Millan, Lauren Loebach, Rubén Blachman-Braun, Milan H. Patel, Jaskirat Saini, William Marston Linehan, Mark Wayne Ball · 2025 · Current Oncology
  39. LncRNA‐HOTAIRM1 promotes aerobic glycolysis and proliferation in osteosarcoma via the miR ‐664b‐3p/Rheb/ mTOR pathway
    Xuecheng Yu, Weihao Duan, Furen Wu, Daibin Yang, Xin Wang, Jingbin Wu, Dong Zhou, Yifei Shen · 2023 · Cancer Science
  40. Underactivation of the adiponectin–adiponectin receptor 1 axis in clear cell renal cell carcinoma: implications for progression
    Nir Kleinmann, Wilhelmina Duivenvoorden, Sarah Hopmans, Laura K. Beatty, Shengjun Qiao, Daniel Gallino, Šárka Lhoták, Dean Daya, Athanasios Paschos, Richard C. Austin et al. · 2013 · Clinical & Experimental Metastasis
  41. Nitrogen Trapping as a Therapeutic Strategy in Tumors with Mitochondrial Dysfunction
    Hanumantha Rao Madala, Iiro Taneli Helenius, Wen Zhou, Evanna L. Mills, Yiyun Zhang, Yan Liu, Ana Marguerita Metelo, Michelle L. Kelley, Surendra Reddy Punganuru, Kyung Bo Kim et al. · 2020 · Cancer Research
  42. Targeting Krebs-cycle-deficient renal cell carcinoma with Poly ADP-ribose polymerase inhibitors and low-dose alkylating chemotherapy
    Daiki Ueno, Juan C. Vasquez, Amrita D. Sule, Jiayu Liang, Jinny Van Doorn, Ranjini K. Sundaram, Sam Friedman, Randy Caliliw, Shinji Ohtake, Xun Bao et al. · 2022 · Oncotarget
  43. Improving our understanding of papillary renal cell carcinoma with integrative genomic analysis
    Parth K. Modi, Eric A. Singer · 2016 · Annals of Translational Medicine
  44. Targeting NAD+ Metabolism Vulnerability in FH-Deficient Hereditary Leiomyomatosis and Renal Cell Carcinoma with the Novel NAMPT Inhibitor OT-82
    Susana Sarai Najera, Christopher J. Ricketts, Laura S. Schmidt, Julia I. Medina, Keita Saito, Lilia V. Ileva, Jeffrey Brender, Amy E. James, Cody J. Peer, Brad A. Gouker et al. · 2024 · Molecular Cancer Therapeutics
  45. The solute carrier family 11 transporters: a bridge between iron homeostasis and tumor biology
    Ruchira Banerjee, Bintee Bintee, Mukesh Kumar Manickasamy, Shristy Jha, Mohammed Saeed Alqahtani, Mohamed Abbas, Arul Goel, Gautam Sethi, Zhaowu Ma, Ajaikumar Bahulayan Kunnumakkara · 2025 · Cell Communication and Signaling
  46. The Role of Ferric Nitrilotriacetate in Renal Carcinogenesis and Cell Death: From Animal Models to Clinical Implications
    Yasumasa Okazaki · 2022 · Cancers
  47. Lysosome–Iron–Mitochondria Axis in Osteoclasts: Iron as a Central Player
    Shengnan Qin, Kathleen M. Davern, Scott G. Wilson, Kai Chen, Aiguo Li, Jiake Xu · 2025 · Research
  48. The role of immunomodulatory metabolites in shaping the inflammatory response of macrophages
    Doyoung Park, Gyumin Lim, Sung‐Jin Yoon, Hyon‐Seung Yi, Dong Wook Choi · 2022 · BMB Reports
  49. Mitochondrial Tumor Suppressors—The Energetic Enemies of Tumor Progression
    Pavel Jakoubě, Valentina Cutano, Juan M. González-Morena, Zuzana Keckesova · 2021 · Cancer Research
  50. Fumarate hydratase inhibits non‑small cell lung cancer metastasis via inactivation of AMPK and upregulation of DAB2
    Anupama Vadhan, Yi‐Fang Yang, Yun‐Ming Wang, Pang‐Yu Chen, Shey-Cherng Tzou, Kuang‐Hung Cheng, Stephen Chu‐Sung Hu, Tian‐Lu Cheng, Yen‐Yun Wang, Shyng‐Shiou F. Yuan · 2022 · Oncology Letters
  51. Therapeutic Strategies for Hereditary Kidney Cancer
    Abhinav Sidana, Ramaprasad Srinivasan · 2016 · Current Oncology Reports
  52. Identification of metabolic changes leading to cancer susceptibility in Fanconi anemia cells
    Etna Abad, Sara Samino, Robert L. Grodzicki, Giovanni Pagano, Marco Trifuoggi, Dmitry Graifer, David Potěšil, Zbyněk Zdráhal, Óscar Yanes, Alex Lyakhovich · 2020 · Cancer Letters
  53. The pathological and molecular genetic landscape of the hereditary renal cancer predisposition syndromes
    Khaleel I. Al‐Obaidy, Zainab I. Alruwaii, Sean R. Williamson, Liang Cheng C · 2022 · Histopathology
  54. Fumarate accumulation involved in renal diabetic fibrosis in Goto-Kakizaki rats
    Yuri Miura, Atsuko Hayakawa, Shohei Kikuchi, Hiroki Tsumoto, Keitaro Umezawa, Yuko Chiba, Yurie Soejima, Motoji Sawabe, Koji Fukui, Yoshihiro Akimoto et al. · 2019 · Archives of Biochemistry and Biophysics
  55. The Metabolic Basis of Kidney Cancer
    Ramaprasad Srinivasan, Arvin Koruthu George, William Marston Linehan · 2015 · Springer eBooks
  56. Preclinical evidence of the enhanced effectiveness of combined rapamycin and AICAR in reducing kidney cancer
    Sitai Liang, Edward Antonio Medina, Boajie Li, Samy L. Habib · 2018 · Molecular Oncology
  57. Metabolic Impairments Caused by a “Chemical Cocktail” of DDE and Selenium in Mice Using Direct Infusion Triple Quadrupole Time-of-Flight and Gas Chromatography–Mass Spectrometry
    Gema Rodríguez‐Moro, Nieves Abril, Rocío Jara-Biedma, Sara Ramírez‐Acosta, José Luis Gómez‐Ariza, Tamara García‐Barrera · 2019 · Chemical Research in Toxicology
  58. Review: Warburg effect and renal cancer caused by errs in fumarate hydratase encoding gene.
    Aminah Suhail Qureshi, Sikander Ali · 2019 · PubMed
  59. Long noncoding RNAs regulating enzymatic reactions in cancer
    Chang Hoon Shin, Kyung‐Min Kim, Chul Woong Ho, Ji Won Lee, Min Jeong Jo, Kyung‐Won Min, Je‐Hyun Yoon · 2025 · Experimental & Molecular Medicine
  60. Untargeted metabolomic and proteomic analysis implicates SIRT2 as a novel therapeutic target for diabetic nephropathy
    Ruijing Zhang, Runze Chang, Heng Wang, Jinshan Chen, Chuanlong Lu, Keyi Fan, Yuhang Zhang, Lizheng Li, Sheng Yan, Honglin Dong · 2025 · Scientific Reports
  61. The Metabolism of Renal Cell Carcinomas and Liver Cancer
    Tu Anh Nguyen, Anne Le · 2018 · Advances in experimental medicine and biology
  62. Effects of cell-cell crosstalk on gene expression patterns in a cell model of renal cell carcinoma lung metastasis
    Katarzyna Kamińska, Anna Malgorzata Czarnecka, Mohammed Imran Khan, Wojciech M Fendler, Aleksandra Klemba, Paweł Krasowski, Ewa Bartnik, Cezary A. Szczylik · 2017 · International Journal of Oncology
  63. Positive feedback loop involving AMPK and CLYBL acetylation links metabolic rewiring and inflammatory responses
    Wenke Wang, Boquan Wu, Mingjun Hao, Sichong Chen, Ruiting Cong, Wenjie Wu, Pengbo Wang, Qiaoyi Zhang, Pengyu Jia, Yuequn Song et al. · 2025 · Cell Death and Disease
  64. HIF2α, Hepcidin and their crosstalk as tumour-promoting signalling
    Vincenzo Formica, Silvia Riondino, Cristina Morelli, Simona Guerriero, Federica D’Amore, Antonio Di Grazia, G. Del Vecchio Blanco, Giuseppe Sigismondo Sica, Hendrik‐Tobias Arkenau, Giovanni Monteleone et al. · 2023 · British Journal of Cancer
  65. DIAMMONIUM GLYCYRRHIZINATE INHIBITED INFLAMMATORY RESPONSE AND MODULATED SERUM METABOLISM IN POLY(I:C)-INDUCED PNEUMONIA MODEL MICE
    Yan Meng, Xuanlin Cai, Shan Cong, Jiao Sun, Wenjing Du, Huantian Cui, Li Luo, Xiumin Ma, Li Wang · 2024 · Shock
  66. Towards a metabolic therapy of cancer?
    Martina Chiu, Laura Ottaviani, Massimiliano Giovanni Bianchi, R. Franchi‐Gazzola, Ovidio Bussolati · 2012 · Acta bio-medica dell'Ateneo parmense/Acta biomedica
  67. Expression profiles and prognostic values of BolA family members in ovarian cancer
    Mingyang Zhu, Shiqi Xiao · 2021 · Journal of Ovarian Research
  68. Cryptic splice mutation in the fumarate hydratase gene in patients with clinical manifestations of Hereditary Leiomyomatosis and Renal Cell Cancer
    Daniel R. Crooks, Geetha Mariah Cawthon, Christina M. Fitzsimmons, Minervo Perez, Christopher J. Ricketts, Cathy D. Vocke, Ye Yang, Lindsay A. Middelton, Debbie Nielsen, Laura S. Schmidt et al. · 2023 · Human Molecular Genetics
  69. Functional Characterization of FH Mutation c.557G>A Underlies Uterine Leiomyomas
    Ping Li, Yanru Wu, Huizhi Wu, Qiuhong Xiong, Na Zhao, Guangxin Chen, Changxin Wu, Xiao Han · 2022 · International Journal of Molecular Sciences
  70. Metabolic Adaptation as Potential Target in Papillary Renal Cell Carcinomas Based on Their In Situ Metabolic Characteristics
    Ildikó Krencz, Enikő Vetlényi, Titanilla Dankó, Gábor Petővári, Dorottya Moldvai, Dániel Sztankovics, Regina Eszter Raffay, Katalin Viola Mészáros, Endre Sebestyén, Gyula Végső et al. · 2022 · International Journal of Molecular Sciences
  71. Metabolism and Oxidative Stress Response Pathways in Kidney Cancer: A Tale of Chance and Necessity
    Carole Sourbier, Ramaprasad Srinivasan, William Marston Linehan · 2015 · American Society of Clinical Oncology Educational Book
  72. Heterogeneous adaptation of cysteine reactivity to a covalent oncometabolite
    Minervo Perez, Daniel W. Bak, Sarah E. Bergholtz, Daniel R. Crooks, Bhargav S. Arimilli, Youfeng Yang, Eranthie Weerapana, William Marston Linehan, Jordan L. Meier · 2020 · Journal of Biological Chemistry
  73. Integrated multi-omics analysis reveals a glycolytic signature that predicts pan-cancer immune checkpoint inhibitor response and LDHA as a combinatorial target in fumarate hydratase-deficient renal cell carcinoma
    Songyang Liu, Yunlong Yuan, Junzhe He, Yihan Zhou, Yuan Wang, Xinqi Ye, Jianfeng Wang, Jin Zhang · 2025 · Frontiers in Immunology
  74. Hydrophilic interaction liquid chromatography coupled with MS / MS to detect and quantify dicarboxyethyl glutathione, a metabolic biomarker of the fumarate hydratase deficient cancer cell
    Hien P. Nguyen, Navdeep S. Chandel, Ralph J. DeBerardinis, Kevin A. Schug · 2013 · Journal of Separation Science
  75. Ferrous glycinate regulates cell energy metabolism by restrictinghypoxia-induced factor-1α expression in human A549 cells
    Huang-Tsung Kuo, Jhong-Huei Jheng, Mei‐Chen Lo, Wei-Lu Chen, Shyang‐Guang Wang, Horng-Mo Lee · 2018 · Free Radical Research
  76. Fumarate hydratase-deficient renal cell carcinoma cells respond to asparagine by activation of the unfolded protein response and stimulation of the hexosamine biosynthetic pathway
    Rony Panarsky, Daniel R. Crooks, Andrew N. Lane, Youfeng Yang, Teresa Cassel, Teresa W.‐M. Fan, William Marston Linehan, Jeffrey A. Moscow · 2020 · Cancer & Metabolism
  77. The Metabolism of Cell Growth and Proliferation
    Lydia W.S. Finley, Craig B. Thompson · 2015 · Elsevier eBooks
  78. Genetics of Renal Cell Carcinoma
    Mark Wayne Ball, William Marston Linehan · 2018 · Springer eBooks
  79. AKT as Locus of Hydrogen Bond Network in Cancer
    Ziv Manasija Radisavljevic · 2017 · Journal of Cellular Biochemistry
  80. Pseudohypoxia, Mitochondrial Mutations, the Warburg Effect, and Cancer.
    Edward Sanders · 2012
  81. Chinese Medicines for Cancer Treatment from the Metabolomics Perspective
    Wei Guo, Hor‐Yue Tan, Ning Wang, Yibin Feng · 2019 · IntechOpen eBooks
  82. RB1 loss induces quiescent state through downregulation of RAS signaling in mammary epithelial cells
    Linxiang Gong, Dominic Chih‐Cheng Voon, Joji Nakayama, Chiaki Takahashi, Susumu Kohno · 2024 · Cancer Science
  83. The Heterogeneity Metabolism of Renal Cell Carcinomas
    Mohammadreza Zarisfi, Tu Anh Nguyen, Jessie R. Nedrow, Anne Le · 2021 · Advances in experimental medicine and biology
  84. PI5P4Kα promotes glucose and iron acquisition to support metabolic fitness in pancreatic cancer
    Gurpreet K. Arora, Ryan M. Loughran, Kyanh Ly, Cheska Marie Galapate, Alicia Llorente Lope, Taylor R. Anderson, Cynthia Y. Zhang, Shea F. Grenier, Ling Li, Sophia Crabtree et al. · 2025 · Cell Reports
  85. The Role of Morphology in Predicting Fumarate Hydratase–deficient Uterine Leiomyomas in Young Women
    Aysel Bayram, Sidar Bağbudar, Hamdullah Sözen, Semen Yeşil Önder, Ekrem Yavuz · 2023 · Applied immunohistochemistry & molecular morphology
  86. Metabolic Pathways of Eukaryotes and Connection to Cell Mechanics
    Claudia Tanja Mierke · 2020 · Biological and medical physics, biomedical engineering
  87. Molecular Genetics of Renal Cell Carcinoma
    Tomoya Fukawa, Nicholas Brian Shannon, Dachuan Huang, Jing Ying Tan, Xiaosai Yao, Steve Rozen, Patrick Tan, Bin Tean Teh · 2017 · Springer eBooks
  88. Case report: Going through pregnancy safely after twice partial nephrectomy for bilateral kidneys with HLRCC-associated RCC
    Kunhan Dai, Wencheng Jiang, Siyu Chen, Shengjun Luo, Siwei Ding, Delin Wang · 2022 · Frontiers in Oncology
  89. Genetics and Tumor Microenvironment of Renal Cell Carcinoma
    Sari Safaa Khaleel, Christopher J. Ricketts, William Marston Linehan, Mark Wayne Ball, Brandon J. Manley, Samra Turajlic, James Brugarolas, A. Ari Hakimi · 2022 · Société Internationale d’Urologie Journal
  90. Molecular Biology and Genetics of Renal Cell Carcinoma
    Sanaz Noelle Ghafouri, David C. Johnson, Kristen Kelly, Allan J. Pantuck, Alexandra Drakaki · 2019 · Springer eBooks
  91. Course of Multimodal Therapy and Genetic Profile of Hereditary Leiomyomatosis and Renal Cell Carcinoma with Early Recurrence during Adjuvant Therapy after Radical Nephrectomy: A Case Report
    Hiroshi Masuda, Tomonori Sato, Satoko Sato, Takuro Goto, Hiromichi Katayama, Yohei Satake, Takuma Sato, Yoshihide Kawasaki, Naoki Kawamorita, Hidekazu Shirota et al. · 2025 · Urologia Internationalis
  92. Targeting a pathogenic cryptic exon that drives HLRCC to induce exon skipping
    Siddhardha S. Maligireddy, Mariana D. Mandler, Judith C. Lunger, Madeline Yuen, Sneha Kulkarni, Alexendar R. Perez, Christina M. Fitzsimmons, Daniel R. Crooks, Raj Chari, William Marston Linehan et al. · 2025 · Molecular Therapy — Nucleic Acids
  93. IRP2-Hif1α/Hif2α signaling: a novel mechanism of metabolic switch from aerobic glycolysis to oxidative phosphorylation
    Li Zhu, Qionglin Zhou, Lu He, Linxi Chen · 2020 · Acta Biochimica et Biophysica Sinica
  94. Neoplasms of the Kidney
    Gregory T. MacLennan, Liang Cheng C · 2020 · Elsevier eBooks
  95. Comprehensive Molecular Characterization of Papillary Renal-Cell Carcinoma
    Abstr Act · 2016
  96. Cutaneous Hamartoneoplastic Disorders
    Katherine L. Nathanson · 2013 · Elsevier eBooks
  97. Regulation Of Cytochrome C Functions By Phosphorylation
    Gargi Mahapatra · 2016 · Human Biology
  98. Hereditary Syndromes Associated with Kidney Tumors
    Ayhan Özcan, Şeyda Erdoğan, Luan D. Truong · 2019 · Springer eBooks
  99. Molecular Pathology of Kidney Tumors
    Şeyda Erdoğan, Ayhan Özcan, Luan D. Truong · 2019 · Springer eBooks
  100. Mitochondrial metabolism and carcinogenesis
    Siddhesh Aras, Neeraja Purandare, Lawrence I. Grossman · 2021 · Elsevier eBooks