Metabolic Reprogramming: A Cancer Hallmark Even Warburg Did Not Anticipate

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Items 601–700 of 1,011

1. Is Reliance on Mitochondrial Respiration a “Chink in the Armor” of Therapy-Resistant Cancer?
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4. Cell-Autonomous Metabolic Reprogramming in Hypoxia
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5. The long and winding road to the mitochondrial pyruvate carrier
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6. Two-color vibrational imaging of glucose metabolism using stimulated Raman scattering
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7. Mitochondrial dynamics and metastasis
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8. Identification and Validation of Plasma Metabolomic Signatures in Precancerous Gastric Lesions That Progress to Cancer
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9. The Role of SLC7A11 in Cancer: Friend or Foe?
   Sijia Li, Zhenyao Lu, Runbin Sun, Suhan Guo, Fangfang Gao, Bei Cao, Jiye Aa · 2022 · Cancers
10. The Potential Antitumor Effects of Capsaicin
    Inés Díaz‐Laviada, Nieves Rodríguez‐Henche · 2014 · Springer eBooks
11. Phosphatidylinositol-3,4,5-Triphosphate and Cellular Signaling: Implications for Obesity and Diabetes
    Prasenjit Manna, Sushil Kumar Jain · 2015 · Cellular Physiology and Biochemistry
12. Targeting Mitochondrial Metabolism by Inhibiting Autophagy in BRAF-Driven Cancers
    Anne M. Strohecker, Eileen White · 2014 · Cancer Discovery
13. MYC regulates the unfolded protein response and glucose and glutamine uptake in endocrine resistant breast cancer
    Ayesha N. Shajahan‐Haq, Katherine Loree Cook, Jessica L. Schwartz‐Roberts, Ahreej E. Eltayeb, Diane M. Demas, Anni M. Wärri, Caroline O. B. Facey, Leena A Hilakivi-Clarke, Robert C. Clarke · 2014 · Molecular Cancer
14. Vitamin C uncouples the Warburg metabolic switch in KRAS mutant colon cancer
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15. Autophagy is required for PDAC glutamine metabolism
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16. MYC and HIF in shaping immune response and immune metabolism
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17. Wild-type IDH2 promotes the Warburg effect and tumor growth through HIF1α in lung cancer
    Jiangjiang Li, Ya He, Zheqiong Tan, Jingchen Lu, Liling Li, Xin Song, Feng Shi, Longlong Xie, Shuo You, Xiangjian Luo et al. · 2018 · Theranostics
18. Increased Expression of PHGDH and Prognostic Significance in Colorectal Cancer
    Xiao-qin Jia, Shu Zhang, Huijun Zhu, Wei Wang, Jinhong Zhu, Xudong Wang, Jianfeng Qiang · 2016 · Translational Oncology
19. Let-7a-5p inhibits triple-negative breast tumor growth and metastasis through GLUT12-mediated warburg effect
    Yajiao Shi, Yanan Zhang, Fang Ran, Jie Liu, Jing Lin, Xiaopeng Hao, Lihua Ding, Qinong Ye · 2020 · Cancer Letters
20. Histone lactylation bridges metabolic reprogramming and epigenetic rewiring in driving carcinogenesis: Oncometabolite fuels oncogenic transcription
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21. Influence of multidrug resistance and drug transport proteins on chemotherapy drug metabolism
    Helena Joyce, Andrew McCann, MARTIN M. CLYNES, Annemarie Larkin · 2015 · Expert Opinion on Drug Metabolism & Toxicology
22. Retinal Toxicity, in vivo and in vitro, Associated with Inhibition of Nicotinamide Phosphoribosyltransferase
    Tanja S. Zabka, Jatinder Singh, Preeti Dhawan, Bianca M. Liederer, Jason Oeh, M. Ariel Kauss, Yang Xiao, Mark Zak, Tori Lin, Bobbi McCray et al. · 2014 · Toxicological Sciences
23. Metastasis Suppressor KISS1 Seems to Reverse the Warburg Effect by Enhancing Mitochondrial Biogenesis
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24. A Phosphohistidine Proteomics Strategy Based on Elucidation of a Unique Gas-Phase Phosphopeptide Fragmentation Mechanism
    Rob Oslund, Jung‐Min Kee, Anthony D. Couvillon, Vivek N. Bhatia, David H. Perlman, Tom W. Muir · 2014 · Journal of the American Chemical Society
25. A Metabolism Toolbox for CAR T Therapy
    Xuequn Xu, JN Rashida Gnanaprakasam, John William Sherman, Ruoning Wang · 2019 · Frontiers in Oncology
26. Interactions between epigenetics and metabolism in cancers
    Yun, Jihye, Johnson, Jared L., Hanigan, Christin L., Locasale, Jason W. · 2012 · Frontiers in Oncology
27. Discovery and validation of urinary metabotypes for the diagnosis of hepatocellular carcinoma in West Africans
    Nimzing Gwamzhi Ladep, Anthony C. Dona, Matthew R. Lewis, Mary M.E. Crossey, Maud Lemoine, Edith Nonyelum Okeke, Yusuke Shimakawa, Mary John Duguru, Harr Freeya Njai, Haddy K. S. Fye et al. · 2014 · Hepatology
28. GC/TOF-MS-based metabolomic profiling in cultured fibroblast-like synoviocytes from rheumatoid arthritis
    Joong Kyong Ahn, Sooah Kim, Jiwon Hwang, Jungyeon Kim, Kyoung Heon Kim, Hoon‐Suk Cha · 2016 · Joint Bone Spine
29. B-Cell Metabolic Remodeling and Cancer
    Davide G. Franchina, Melanie Grusdat, Dirk Brenner · 2018 · Trends in cancer
30. Artemisinin and Its Synthetic Derivatives as a Possible Therapy for Cancer
    Enrique Konstat-Korzenny, Jorge Alberto Ascencio-Aragón, Sebastian Niezen, Rosalino Vázquez-López · 2018 · Medical Sciences
31. MicroRNA-129-5p Regulates Glycolysis and Cell Proliferation by Targeting the Glucose Transporter SLC2A3 in Gastric Cancer Cells
    Di Chen, Hui Wang, Jie Chen, Zhe Li, Shengli Li, Zhixiang Hu, Shenglin Huang, Yingjun Zhao, Xianghuo He · 2018 · Frontiers in Pharmacology
32. D-2-Hydroxyglutarate in Glioma Biology
    Fu-Ju Chou, Yang Liu, Fengchao Lang, Chunzhang Yang · 2021 · Cells
33. DNA Methylation: From Cancer Biology to Clinical Perspectives
    Chen Chen, Zehua Wang, Yi Ding, Lei Wang, Siyuan Wang, Haonan Wang, Yanru Qin · 2022 · Frontiers in Bioscience-Landmark
34. Cancer‐specific interruption of glucose metabolism by resveratrol is mediated through inhibition of Akt/GLUT1 axis in ovarian cancer cells
    HyeRan Gwak, Guy Haegeman, Benjamin K. Tsang, Yong Sang Song · 2014 · Molecular Carcinogenesis
35. Dependence of Tumor Cell Lines and Patient-Derived Tumors on the NAD Salvage Pathway Renders Them Sensitive to NAMPT Inhibition with GNE-618
    Yang Xiao, Kristi Elkins, Jenni Durieux, Leslie B. Lee, Jason Oeh, Lulu Yang, Xiaorong Liang, Chris DelNagro, Jarrod R. Tremayne, Mandy Kwong et al. · 2013 · Neoplasia
36. The amino acid transporter SLC6A14 in cancer and its potential use in chemotherapy
    Yangzom Doma Bhutia, Ellappan Babu, Puttur Devi Prasad, Vadivel Ganapathy · 2014 · Asian Journal of Pharmaceutical Sciences
37. Multiple roles of glyoxalase 1-mediated suppression of methylglyoxal glycation in cancer biology—Involvement in tumour suppression, tumour growth, multidrug resistance and target for chemotherapy
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38. miR-147b-mediated TCA cycle dysfunction and pseudohypoxia initiate drug tolerance to EGFR inhibitors in lung adenocarcinoma
    Wen Cai Zhang, Julie M. Wells, Kin-Hoe Chow, He Huang, Min Yuan, Tanvi Saxena, Mary Ann Melnick, Katerina A. Politi, John M. Asara, Daniel Botelho Costa et al. · 2019 · Nature Metabolism
39. Regulation of Metabolic Activity by p53
    Flöter, Jessica, Kaymak, Irem, Schulze, Almut · 2017 · Metabolites
40. Potent organo-osmium compound shifts metabolism in epithelial ovarian cancer cells
    Jessica M. Hearn, Isolda Romero‐Canelón, Alison F. Munro, Ying Fu, Ana M. Pizarro, Mathew J. Garnett, Ultan McDermott, Neil O. Carragher, Peter John Sadler · 2015 · Proceedings of the National Academy of Sciences
41. Interplay between sirtuins, MYC and hypoxia-inducible factor in cancer-associated metabolic reprogramming
    Bernadette M. M. Zwaans, David B. Lombard · 2014 · Disease Models & Mechanisms
42. Ginkgolic acid suppresses the development of pancreatic cancer by inhibiting pathways driving lipogenesis
    Jiguang Ma, Wanxing Duan, Suxia Han, Jianjun Lei, Qinhong Xu, Xin Chen, Zhengdong Jiang, Ligang Nan, Jiahui Li, Ke Chen et al. · 2015 · Oncotarget
43. MicroRNA‐124‐3p regulates cell proliferation, invasion, apoptosis, and bioenergetics by targeting PIM1 in astrocytoma
    Danni Deng, Lei Wang, Yao Chen, Bowen Li, Lian Xue, Nan Shao, Qiang Wang, Xiwei Xia, Yilin Yang, Feng Zhi · 2016 · Cancer Science
44. Mitochondrial Metabolism-Mediated Regulation of Adult Neurogenesis
    Ruth Beckervordersandforth · 2017 · Brain Plasticity
45. Methionine metabolism is essential for SIRT1‐regulated mouse embryonic stem cell maintenance and embryonic development
    Shuang Tang, Yi Fang, Gang Huang, Xiaojiang Xu, Elizabeth Padilla‐Banks, Wei Fan, Qing Xu, Sydney M. Sanderson, Julie F. Foley, Scotty Dowdy et al. · 2017 · The EMBO Journal
46. Tumor diversity and the trade-off between universal cancer tasks
    Jean Hausser, Pablo Székely, Noam Bar, Anat Zimmer, Hila Sheftel, Carlos Caldas, Uri Alon · 2019 · Nature Communications
47. Distinct metabolic hallmarks of WHO classified adult glioma subtypes
    Benny Björkblom, Carl Wibom, Maria Eriksson, A. Tommy Bergenheim, Rickard L. Sjöberg, Pär Jonsson, Thomas Brännström, Henrik Antti, Maria Sandström, Beatrice S. Melin · 2022 · Neuro-Oncology
48. Blocking glycine utilization inhibits multiple myeloma progression by disrupting glutathione balance
    Jiliang Xia, Jingyu Zhang, Xuan Wu, Wanqing Du, Yinghong Zhu, Xing Liu, Zhenhao Liu, Bin Meng, Jiaojiao Guo, Qin Zhao Yang et al. · 2022 · Nature Communications
49. Structure-Based Identification of Ureas as Novel Nicotinamide Phosphoribosyltransferase (Nampt) Inhibitors
    Xiaozhang Zheng, Paul Bauer, Timm Baumeister, Alexandre J. Buckmelter, Maureen Caligiuri, Karl H. Clodfelter, Bingsong Han, Yen‐Ching Ho, Nikolai Kley, Jian Lin et al. · 2013 · Journal of Medicinal Chemistry
50. Metabolism pathways in chronic lymphocytic leukemia
    Uri Rozovski, Inbal Hazan‐Halevy, Merav Barzilai, Michael J. Keating, Zeev E. Estrov · 2015 · Leukemia & lymphoma/Leukemia and lymphoma
51. Cyclin-Dependent Kinase Co-Ordinates Carbohydrate Metabolism and Cell Cycle in S. cerevisiae
    Gang Zhao, Yuping Chen, Lucas B. Carey, Bruce Futcher · 2016 · Molecular Cell
52. IL-1/inhibitory κB kinase ε–induced glycolysis augment epithelial effector function and promote allergic airways disease
    Xi Qian, Reem Aboushousha, Cheryl van de Wetering, Shi Biao Chia, Eyal Amiel, Robert W. Schneider, Jos L. J. van der Velden, Karolyn G. Lahue, Daisy A. Hoagland, Dylan T. Casey et al. · 2017 · Journal of Allergy and Clinical Immunology
53. Dysregulation of Glucose Metabolism by Oncogenes and Tumor Suppressors in Cancer Cells
    Casterland Marbaniang, Lakhan Kma · 2018 · Europe PMC (PubMed Central)
54. Heat Oscillations Driven by the Embryonic Cell Cycle Reveal the Energetic Costs of Signaling
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55. A Metabolic Landscape for Maintaining Retina Integrity and Function
    Filipe Viegas, Stephan C. F. Neuhauss · 2021 · Frontiers in Molecular Neuroscience
56. In silico development and clinical validation of novel 8 gene signature based on lipid metabolism related genes in colon adenocarcinoma
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57. The mixed blessing of AMPK signaling in Cancer treatments
    Mehrshad Sadria, Deokhwa Seo, Anita T. Layton · 2022 · BMC Cancer
58. INTEGRATE: Model-based multi-omics data integration to characterize multi-level metabolic regulation
    Marzia Di Filippo, Dario Pescini, Bruno G. Galuzzi, Marcella Bonanomi, Daniela Gaglio, Eleonora Mangano, Clarissa Consolandi, Lilia Alberghina, Marco Vanoni, Chiara Damiani · 2022 · PLoS Computational Biology
59. The Evolving, Multifaceted Roles of Autophagy in Cancer
    Jing Liu, Jayanta Debnath · 2016 · Advances in cancer research
60. Expression and putative role of mitochondrial transport proteins in cancer
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61. Quantitative proteomics by SWATH-MS reveals sophisticated metabolic reprogramming in hepatocellular carcinoma tissues
    Yanyan Gao, Xinzheng Wang, Zhihong Sang, Zongcheng Li, Feng Liu, Jie Mao, Dan Yan, Yongqiang Zhao, Hongli Wang, Ping Li et al. · 2017 · Scientific Reports
62. VersicanV1 promotes proliferation and metastasis of hepatocellular carcinoma through the activation of EGFR–PI3K–AKT pathway
    Guangyan Zhangyuan, Fei Wang, Haitian Zhang, Runqiu Jiang, Xuewen Tao, Decai Yu, Kangpeng Jin, Weiwei Yu, Yang Liu, Yin Yin et al. · 2019 · Oncogene
63. Bone marrow mesenchymal stem cell-derived exosomal miR-21a-5p alleviates renal fibrosis by attenuating glycolysis by targeting PFKM
    Shihao Xu, Yin Celeste Cheuk, Yichen Jia, Tian Chen, Juntao Chen, Yongsheng Luo, Yirui Cao, Jingjing Guo, Lijun Dong, Yi Zhang et al. · 2022 · Cell Death and Disease
64. Bistability in Glycolysis Pathway as a Physiological Switch in Energy Metabolism
    Bhanu Chandra Mulukutla, Andrew Yongky, Pródromos Daoutidis, Wei‐Shou Hu · 2014 · PLoS ONE
65. PHLPP regulates hexokinase 2-dependent glucose metabolism in colon cancer cells
    Xiaopeng Xiong, Yang‐An Wen, Mihail I. Mitov, Mary C Oaks, Shigeki Miyamoto, Tianyan Gao · 2017 · Cell Death Discovery
66. Clinical implications of the oncometabolite succinate in SDHx ‐mutation carriers
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67. Mass spectrometry imaging-based metabolomics to visualize the spatially resolved reprogramming of carnitine metabolism in breast cancer
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68. Moonlighting enzymes: when cellular context defines specificity
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69. Molecular Pathways: The Metabolic Regulator Estrogen-Related Receptor α as a Therapeutic Target in Cancer
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70. Biomarkers for hepatocellular carcinoma: progression in early diagnosis, prognosis, and personalized therapy
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71. Minireview: Obesity and Breast Cancer: A Tale of Inflammation and Dysregulated Metabolism
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72. Role of mitochondrial function in the invasiveness of human colon cancer cells
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73. Fatty acid oxidation is associated with proliferation and prognosis in breast and other cancers
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74. Sirtuins in Metabolic and Epigenetic Regulation of Stem Cells
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75. O-GlcNAcase targets pyruvate kinase M2 to regulate tumor growth
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76. Berberine and Emodin abrogates breast cancer growth and facilitates apoptosis through inactivation of SIK3-induced mTOR and Akt signaling pathway
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77. Introduction to the molecular basis of cancer metabolism and the Warburg effect
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78. Myoferlin regulates cellular lipid metabolism and promotes metastases in triple-negative breast cancer
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79. Sirtuin 4 Depletion Promotes Hepatocellular Carcinoma Tumorigenesis Through Regulating Adenosine‐Monophosphate–Activated Protein Kinase Alpha/Mammalian Target of Rapamycin Axis in Mice
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80. Next-Generation NAMPT Inhibitors Identified by Sequential High-Throughput Phenotypic Chemical and Functional Genomic Screens
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81. Exploiting tumor metabolism: challenges for clinical translation
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82. Systematic Analysis of the Expression of the Mitochondrial ATP Synthase (Complex V) Subunits in Clear Cell Renal Cell Carcinoma
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83. Engineering Supramolecular Nanomedicine for Targeted Near Infrared-triggered Mitochondrial Dysfunction to Potentiate Cisplatin for Efficient Chemophototherapy
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84. MicroRNAs as regulators of mitochondrial function: Role in cancer suppression
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85. Underestimation of the Maximal Capacity of the Mitochondrial Electron Transport System in Oligomycin-Treated Cells
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86. Histone demethylase LSD1 controls the phenotypic plasticity of cancer cells
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87. PDK1 promotes ovarian cancer metastasis by modulating tumor-mesothelial adhesion, invasion, and angiogenesis via α5β1 integrin and JNK/IL-8 signaling
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88. α-Ketoglutaramate: an overlooked metabolite of glutamine and a biomarker for hepatic encephalopathy and inborn errors of the urea cycle
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89. MicroRNAs and oncogenic transcriptional regulatory networks controlling metabolic reprogramming in cancers
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90. Metabolic Alterations in Cancer and Their Potential as Therapeutic Targets
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91. The anabolic role of the Warburg, Cori-cycle and Crabtree effects in health and disease
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92. Astrocytes: GABAceptive and GABAergic Cells in the Brain
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93. Targeting glycolysis in non-small cell lung cancer: Promises and challenges
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94. Primary clear cell renal carcinoma cells display minimal mitochondrial respiratory capacity resulting in pronounced sensitivity to glycolytic inhibition by 3-Bromopyruvate
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95. Autophagy-related gene 12 (ATG12) is a novel determinant of primary resistance to HER2-targeted therapies: Utility of transcriptome analysis of the autophagy interactome to guide breast cancer treatment
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96. Metabolic clusters of breast cancer in relation to gene- and protein expression subtypes
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97. Importance of the Microbiota Inhibitory Mechanism on the Warburg Effect in Colorectal Cancer Cells
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98. Links between cancer metabolism and cisplatin resistance
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99. Amino Acids and mTOR Mediate Distinct Metabolic Checkpoints in Mammalian G1 Cell Cycle
    Mahesh Saqcena, Deepak Menon, Deven Patel, Suman Mukhopadhyay, Victor Chow, David A. Foster · 2013 · PLoS ONE
100. Mitochondrial Targeting of Metformin Enhances Its Activity against Pancreatic Cancer
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