Leukemia Propagating Cells Rebuild an Evolving Niche in Response to Therapy

Hallmarks of Cancer: The Next Generation

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Mesenchymal stromal cells contribute to quiescence of therapy‐resistant leukemic cells in acute myeloid leukemia

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Bone Marrow Aging and the Leukaemia-Induced Senescence of Mesenchymal Stem/Stromal Cells: Exploring Similarities

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Macro-scale, scaffold-assisted model of the human bone marrow endosteal niche using hiPSC-vascularized osteoblastic organoids

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Phenotypic and Functional Alterations of Hematopoietic Stem and Progenitor Cells in an In Vitro Leukemia-Induced Microenvironment

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Phenotypic, genotypic, and functional characterization of normal and acute myeloid leukemia-derived marrow endothelial cells

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Young donor hematopoietic stem cells revitalize aged or damaged bone marrow niche by transdifferentiating into functional niche cells

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BCL6 modulation of acute lymphoblastic leukemia response to chemotherapy

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Driver Mutations in Leukemia Promote Disease Pathogenesis through a Combination of Cell-Autonomous and Niche Modulation

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Targeting DNA polymerase β elicits synthetic lethality with mismatch repair deficiency in acute lymphoblastic leukemia

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Targeted Therapies: Friends or Foes for Patient’s NK Cell-Mediated Tumor Immune-Surveillance?

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Distinct and targetable role of calcium-sensing receptor in leukaemia

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Molecular mechanisms for stemness maintenance of acute myeloid leukemia stem cells

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Recent progress on targeting leukemia stem cells

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Distinct stromal cell populations define the B-cell acute lymphoblastic leukemia microenvironment

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Combination of cabazitaxel and plicamycin induces cell death in drug resistant B-cell acute lymphoblastic leukemia

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The Immune Checkpoint ICOSLG is a Relapse-Predicting Biomarker and Therapeutic Target in Infant t(4;11) Acute Lymphoblastic Leukemia

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B- and T-cell acute lymphoblastic leukemias evade chemotherapy at distinct sites in the bone marrow

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Dormancy Stems the Tide of Chemotherapy

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B-cell precursor acute lymphoblastic leukemia elicits an interferon-α/β response in bone marrow-derived mesenchymal stroma

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The evolution of leukaemia from pre‐leukaemic and leukaemic stem cells

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Expression of the fetal hematopoiesis regulator FEV indicates leukemias of prenatal origin

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Pediatric precursor B acute lymphoblastic leukemia: are T helper cells the missing link in the infectious etiology theory?

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The role of microenvironment in the initiation and evolution of B-cell precursor acute lymphoblastic leukemia

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Post‐hematopoietic stem cell transplantation relapse: Role of checkpoint inhibitors

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High expression of connective tissue growth factor accelerates dissemination of leukaemia

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Leukaemic alterations of IKZF1 prime stemness and malignancy programs in human lymphocytes

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DEX‐Induced SREBF1 Promotes BMSCs Differentiation into Adipocytes to Attract and Protect Residual T‐Cell Acute Lymphoblastic Leukemia Cells After Chemotherapy

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FEV Maintains Homing and Expansion by Activating ITGA4 Transcription in Primary and Relapsed AML

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Cancer-associated fibroblasts in acute leukemia

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Establishment and characterization of HXWMF-1: the first mouse fibroblastic tumor cell line derived from leukemia-associated fibroblasts

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Sensitization to Drug Treatment in Precursor B-Cell Acute Lymphoblastic Leukemia Is Not Achieved by Stromal NF-κB Inhibition of Cell Adhesion but by Stromal PKC-Dependent Inhibition of ABC Transporters Activity

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A proinflammatory response and polarized differentiation of stromal elements characterizes the murine myeloma bone marrow niche

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Drug-tolerant persister cells in acute myeloid leukemia: pressing challenge and promising new strategies for treatment

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Cancer associated fibroblasts in tumors: focusing on solid tumors and hematological malignancies

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Nestin+ Mesenchymal Stromal Cells Fibrotic Transition Mediated by CD169+ Macrophages in Bone Marrow Chronic Graft-versus-Host Disease

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Extracellular Vesicles Derived from Human Bone Marrow Stem Cells Inhibit Acute Lymphoblastic Leukemia Cell Growth by Inhibiting MAPK Pathway via the miR-29b-3p/GDF15 Axis

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Nanoparticle-encapsulated retinoic acid for the modulation of bone marrow hematopoietic stem cell niche

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Defined, serum/feeder-free conditions for expansion and drug screening of primary B-acute lymphoblastic leukemia

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Characteristics and Therapeutic Targeting of Minimal Residual Disease in Childhood Acute Lymphoblastic Leukemia

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MRD in Acute Leukemias: Lessons Learned from Acute Promyelocytic Leukemia

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Towards deciphering the bone marrow microenvironment with spatial multi-omics

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Bone marrow T helper cells with a Th1 phenotype induce activation and proliferation of leukemic cells in precursor B acute lymphoblastic leukemia patients

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Cortactin Expression is a Novel Biomarker for Risk Stratification of T-Cell Acute Lymphoblastic Leukemia

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A human mesenchymal spheroid prototype to replace moderate severity animal procedures in leukaemia drug testing

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Innovative combinatory approaches with dendritic cell-based vaccines: bridging preclinical insights and clinical challenges

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A human mesenchymal spheroid prototype to replace moderate severity animal procedures in leukaemia drug testing

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High-throughput formulation of reproducible 3D cancer microenvironments for drug testing in myeloid leukemia

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Chemotherapy-initiated cysteine-rich protein 61 decreases acute B-lymphoblastic leukemia chemosensitivity

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Bone Marrow Stromal Niche: A New Master Regulator of Hematological Myeloid Malignancies

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Leukemic Cells Infiltrate the Ovaries Without Damaging Ovarian Reserve in an Acute Myeloid Leukemia Mouse Model

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Nonionotropic action of an acid-sensing ion channel inhibits leukemogenesis in the acidic bone marrow niche

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Clonal evolution in leukemia: preleukemia, evolutionary models, and clinical implications

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Translating molecular insights into clinical success: alkaloid-based therapies for leukemia

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Residual Disease in a Novel Xenograft Model of RUNX1-Mutated, Cytogenetically Normal Acute Myeloid Leukemia

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Patient-Derived Tumor Xenografts in Hematologic Disorders

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Relapsed Acute Lymphoblastic Leukemia of Childhood

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Cancer research driven by cutting-edge multi-disciplinary technologies

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High-throughput formulation of reproducible 3D cancer microenvironments for drug testing in myelogenous leukemiaPreprint

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Leukemia cell mobilization: a road to eradication?

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Advances in the application of patient-derived xenograft models in acute leukemia resistance

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Favorable and poor prognosis B‐cell precursor acute lymphoblastic leukemia subtypes reveal distinct leukemic cell properties when interacting with mesenchymal stem cells, differentially modifying their cell stemness and leukemia chemoresistance

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Interleukin-27 remodels the bone marrow niche to suppress B-cell development and leukaemia progression in mouse models

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Updated Landscape of the Tumor Microenvironment and Targeting Strategies in an Era of Precision Medicine

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Post-Irradiation Hyperamylasemia Is a Prognostic Marker for Allogeneic Hematopoietic Stem Cell Transplantation Outcomes in Pediatric Population: A Retrospective Single-Centre Cohort Analysis

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Neoplasms in the bone marrow niches: disturbance of the microecosystem

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A Forecast of Targeting Leukemia Stem Cells by Nanomedicine

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The Hematopoietic Niche and Bone

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Co-culture with leukemia cells decreases proliferation and increases chemoprotective capacity of normal mesenchymal stromal cellsPreprint

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Tunnelling nanotubules are druggable mediators of cancer-niche crosstalkPreprint

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Macrophage-secreted Pyrimidine Metabolites Confer Chemotherapy Resistance in Acute Myeloid Leukemia (AML)Preprint

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Bone Marrow Microenvironment regulation of BCL6 in Acute Lymphoblastic Leukemia

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Defining the Mode of Medulloblastoma Growth using the Ptch1 Heterozygous Mouse Model

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The role of miRNAs in niche regulation of ALL phenotype

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A vérképzőőssejt-niche szerepe a hematológiai neopláziák iniciációjában és progressziójában

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ALL the comforts of homing: lymphoblasts find cerebrospinal fluid inhospitable without meningeal cell contact

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The Role of Bone Stem Cell Niches in Bone Metastasis

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Acute lymphoblastic leukemia and the bone marrow microenvironment

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