Aging and reprogramming: a two-way street

Mahmoudi, Salah, Brunet, Anne·2012·Current Opinion in Cell Biology

Cited by (179)

Items 101–179 of 179

  1. Induced pluripotent stem cells in companion animals: how can we move the field forward?
    Laura Barrachina, Tarlan Eslami Arshaghi, Aisling O’Brien, Ana Ivanovska, Frank Barry · 2023 · Frontiers in Veterinary Science
  2. Epigenetic reprogramming for ocular aging and disease: Mechanisms, biomarkers, and the road to the clinic
    Junwon Lee, Minseok Han, Kaixiang Wang, L.Rainer Butler, David A. Sinclair · 2026 · Progress in Retinal and Eye Research
  3. Regenerative medicine: Induced pluripotent stem cells and their benefits on accelerated bone tissue reconstruction using scaffolds
    Nowsheen Goonoo, Archana Bhaw‐Luximon · 2018 · Journal of materials research/Pratt's guide to venture capital sources
  4. Human adult pluripotency: Facts and questions
    Luminita Simion Labusca, Kaveh Mashayekhi · 2019 · World Journal of Stem Cells
  5. Use of human pluripotent stem cells to study and treat retinopathies
    Karim Ben M’Barek · 2015 · World Journal of Stem Cells
  6. Restoration of angiogenic capacity in senescent endothelial cells by a pharmacological reprogramming approach
    Katrin Kalies, Kai Knöpp, Susanne Koch, Claudia Pilowski, Leonie Wurmbrand, Daniel Sedding · 2025 · PLoS ONE
  7. Ectopic expression of CITED2 prior to reprogramming, promotes and homogenises the conversion of somatic cells into induced pluripotent stem cells
    João Charneca, Ana Catarina Matias, Ana Luísa Escapa, Catarina Fernandes, André Alves, João Miguel Almeida Santos, Rita Nascimento, José Bragança · 2017 · Experimental Cell Research
  8. Modeling neurodegenerative disorders in adult somatic cells: A critical review
    An Nhien Truong, Emily Si, Thomas Duncan, Michael Valenzuela · 2016 · Frontiers in Biology
  9. Novel Strategy in Searching for Natural Compounds with Anti-Aging and Rejuvenating Potential
    Andrey V. Koptyug, Ю. Г. Суховей, Елена Геннадьевна Костоломова, Irina Unger, Kozlov Va · 2023 · International Journal of Molecular Sciences
  10. Overcoming barriers to reprogramming and differentiation in nonhuman primate induced pluripotent stem cells
    Jacob J. Hemmi, Anuja Mishra, Peter J. Hornsby · 2017 · Primate Biology
  11. Recent progress in the identification and in vitro culture of skin organoids
    Yanan Huang, Qing Ye, Jiyuan Wang, Zhu Kaimin, Haojie Yang, Xiaoping Jiang, Meihua Shen · 2025 · Regenerative Therapy
  12. Stem Cell–Derived Islet Transplantation in Patients With Type 2 Diabetes: Can Diabetes Subtypes Guide Implementation?
    Kevin K. Verhoeff, Braulio A. Marfil‐Garza, Zofia Czarnecka, Nerea Cuesta‐Gomez, Ila Tewari Jasra, Nidheesh Dadheech, Peter Alexander Senior, Andrew M. James Shapiro · 2023 · The Journal of Clinical Endocrinology & Metabolism
  13. Xeno-free generation of human induced pluripotent stem cells from donor-matched fibroblasts isolated from dermal and oral tissues
    Hassan R. W. Ali, Salwa Suliman, Tarig Osman, Manuel Carrasco, Ove Bruland, Daniela Elena Costea, Helge Ræder, Kamal Mustafa · 2023 · Stem Cell Research & Therapy
  14. Human-Induced Pluripotent Stem Cell-Derived Mesenchymal Stem Cells as an Individual-Specific and Renewable Source of Adult Stem Cells
    Glen Lester Sequiera, Saravanan Sekaran, Sanjiv Dhingra · 2017 · Methods in molecular biology
  15. In silico clinical trials for anti-aging therapies
    Javier Abel Menéndez, Elisabet Cuyàs, Núria Folguera-Blasco, Sara Verdura, Begoña Martı́n-Castillo, Jorge Joven, Tomás Alarcón · 2019 · Aging
  16. Detection of Soluble and Insoluble Protein Species in Patient-Derived iPSCs
    Stephanie Santarriaga, Ian W. Luecke, Allison D. Ebert · 2022 · Methods in molecular biology
  17. Effect of Vitamin D Supplementation on Insulin, Fasting Blood Glucose, and Waist-Hip Ratio in Young Females with Pre-existing Vitamin D Deficiency
    Mona Hmoud AlSheikh, Shayma Ibrahim Almubayadh · 2019 · The Indonesian Biomedical Journal
  18. Vasculogenic tissue nanotransfection accelerates functional recovery after peripheral nerve injury
    Ana I. Salazar‐Puerta, Sara Kheirkhah, Jonathan P. Stranan, Hallie N. Harris, Nada Khattab, Megumi Fukuda, Grant Barringer, Carlos A Vasquez-Martinez, Samuel Cortes, Neil Ott et al. · 2026 · Science Advances
  19. Computational systems biology approaches to cellular aging—Integrating network maps and dynamical models
    Hetian Su, Nan Hao · 2025 · Quantitative Biology
  20. Direct conversion of fibroblast into neurons for Alzheimer's disease research: a systematic review
    Sattarov, Roman, Toresson, Håkan, Orbjörn, Camilla, Mattsson-Carlgren, Niklas · 2023 · Journal of Alzheimer’s Disease
  21. The promising prospect of human hair follicle regeneration in the shadow of new tissue engineering strategies
    arezoo karamivandishi, Ali Esmaeili, Niloofar Taghipour · 2024 · Tissue and Cell
  22. Accelerated neuronal aging in vitro ∼melting watch ∼
    Emi Inagaki, Sho Yoshimatsu, Hideyuki Okano · 2022 · Frontiers in Aging Neuroscience
  23. Expansion of the neocortex and protection from neurodegeneration by in vivo transient reprogramming
    Y Shen, Sofía Zaballa, Xavier Bech, Anna Sancho‐Balsells, Carmen Díaz-Cifuentes, Goenuel Seyit-Bremer, Iván Ballasch, Noelia Alcázar, Jordi Alberch, María Abad et al. · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
  24. Elevated p16Ink4a Expression Enhances Tau Phosphorylation in Neurons Differentiated From Human‐Induced Pluripotent Stem Cells
    Kristopher Holloway, Kashfia Neherin, Yingduo Song, Kazuhito Sato, Andrew Houston, Feng Chen, Ding Li, Hong Zhang · 2025 · Aging Cell
  25. Epigenetic regulation of Hutchinson-Gilford progeria syndrome: from molecular mechanisms to targeted interventions
    Xuan Liu, Shuhui Yang, Jiaxiao Jiang, Shasha Dong, Yu Zhang · 2025 · Oral Science and Homeostatic Medicine
  26. Deciphering reprogramming efficiency in human induced pluripotent stem cells: insights from the generation of 150 cell lines
    Bernd Kuebler, Silvia Selvitella, Begoña Arán, Angel Alcaide Raya, Anna Veiga · 2026 · Frontiers in Immunology
  27. In vitro modelling of extracellular matrix changes during skin aging: from static 2D to 3D dynamic microphysiological systems
    Yao Yu, Zilin Zhang, Jing Zhang, Yuan Gao, Xiaoran Li, Keyu Yang, Nuo Si, Zaozao Chen, Zhongze Gu, Ningbei Yin · 2026 · Microsystems & Nanoengineering
  28. A new hypothesis of aging
    Amalia Gabriela Diaconeasa, Mariana Rachita, Raluca‐Ioana Stefan‐van Staden · 2015 · Medical Hypotheses
  29. Early Life Reprogramming-Based Treatment Promotes Longevity
    Patrizia Pessina, Bruno Di Stefano · 2023 · Cellular Reprogramming
  30. Are reprogrammed cells a useful tool for studying dopamine dysfunction in psychotic disorders? A review of the current evidence
    Ulrich Sauerzopf, Roberto Sacco, Gaia Novarino, Marco Niello, Ana Weidenauer, Nicole Praschak-Rieder, Harald H. Sitte, Matthäus Willeit · 2016 · European Journal of Neuroscience
  31. Old fibroblasts secrete inflammatory cytokines that drive variability in reprogramming efficiency and may affect wound healing between old individuals
    Salah Mahmoudi, Elena Mancini, Alessandra L. Moore, Lucy Xu, Fereshteh Jahanbani, Katja Hebestreit, Rajini Srinivasan, Xiyan Li, Keerthana Devarajan, Laurie Prélot et al. · 2018 · bioRxiv (Cold Spring Harbor Laboratory)
  32. Identifying novel age-modulating compounds and quantifying cellular aging using novel computational framework for evaluating transcriptional age
    Chao Zhang, Nathalie G. Saurat, Daniela Cornacchia, Sun Young Chung, Trisha Sikder, Andrew P. Minotti, Lorenz Studer, Doron Betel · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
  33. Bioengineering strategies for regeneration of skin integrity: A literature review
    Makoto Shiraishi, Yoshihiro Sowa, Ataru Sunaga, Kenta Yamamoto, Mutsumi Okazaki · 2024 · Regenerative Therapy
  34. Targeted partial reprogramming as a novel therapeutic strategy for age-related decline
    Max Rose, Eli Y. Adashi · 2025 · Ageing Research Reviews
  35. Introducing Cellular Senescence in Human Induced Pluripotent Stem Cells and Differentiated Neural Lineage for Modeling of Age‐Associated Diseases
    Kashfia Neherin, Kristopher Holloway, Yingduo Song, Andrew Houston, Feng Chen, Li Ding, Hong Zhang · 2026 · Advanced Biology
  36. Bioinformatic and Genomic Analyses of Cellular Reprogramming and Direct Lineage Conversion
    M. Kareta · 2016 · Current Pharmacology Reports
  37. Non-ionizing radiation-induced cellular senescence and age-related diseases
    Haiying Wang, Jian Tong, Yi Cao · 2024 · Radiation Medicine and Protection
  38. The Interplay between Cellular Senescence and Side Population Stem Cells
    Vadim E. Fraifeld, Maria Boichuck, Anna Knyazer, Ekaterina A. Rudnitskaya, Alex Braiman, Orly Gershoni‐Yahalom, Benyamin Rosental, Yael Segev, Marina Wolfson, Khachik K. Muradian et al. · 2025
  39. Repair, regeneration and rejuvenation require un-entangling pluripotency from senescence
    SIAMAK S. TABIBZADEH · 2022 · Ageing Research Reviews
  40. The Aging Epigenome and The Rejuvenation Strategies
    Anna Meiliana, Nurrani Mustika Dewi, Andi Wijaya · 2022 · The Indonesian Biomedical Journal
  41. Senescence Model Theories from In Vitro through In Vivo
    Merve Alpay · 2024 · Düzce Tıp Fakültesi Dergisi
  42. Insights for producing and future use of induced pluripotent stem cells from the small red brocket deer (Mazama jucunda)
    Luana Scarpelini Rosa, Laís Vicari de Figueirêdo Pessôa, Nayanne Sant Clair Cardoso da Silva, Jenyffer Mairely Rosero, Kaiana Recchia, José Maurício Barbanti Duarte, Fabiana Fernandes Bressan · 2026 · Theriogenology Wild
  43. Main Phenotype Subphases in Reprogramming Somatic Cells as a Model of Cellular Differentiation Process
    Víctor Valdespino, Patricia Margarita Valdespino-Castillo, Victor Valdespino Junio · 2013 · American Journal of Biomedical Research
  44. Aging and stability of cardiomyocytes
    Shouvik Chakravarty, Johnson Rajasingh, Satish Ramalingam · 2021 · Elsevier eBooks
  45. The versatile applications of human pluripotent stem cell-derived microglia and microglia-containing brain organoids
    Junjiao Wu, Yu Tang · 2023 · Ageing and Neurodegenerative Diseases
  46. Use of Induced Pluripotent Stem Cells in Aging Research
    Ken‐ichi Isobe · 2015 · Springer eBooks
  47. Fleeting factors, turning back time
    Thomas A. Rando · 2017 · Nature Biotechnology
  48. Mir-195: Roadblock for Reprogramming Aged Cells
    Lin Hong Jiang, Yigang Wang · 2017 · Single Cell Biology
  49. The Relevance of Induced Pluripotent Stem Cells for the Study of Physiological and Premature Aging
    Dido Carrero, Carlos López-Otı́n · 2018 · Springer eBooks
  50. Assessing the Effect of Epigenetic Dysregulation on Oncogenesis and Immunocompetence in a Mouse Model
    Joseph Rosenthal · 2018 · Digital Access to Scholarship at Harvard (DASH) (Harvard University)
  51. Attaining Epigenetic Rejuvenation: Challenges Ahead
    Jogeswar Satchidananda Purohit, Neetika Singh, Shah Saddad Hussain, Madan Mohan Chaturvedi · 2020 · Springer eBooks
  52. Injury and regeneration in renal aging
    Janka Bábíčková, Haichun Yang, Agnes B. Fogo · 2021 · Elsevier eBooks
  53. Dipping a toe in the fountain of youth
    Arianna Markel, George Q. Daley · 2022 · Nature Aging
  54. Faculty Opinions recommendation of Influence of donor age on induced pluripotent stem cells.
    Oliver Brüstle · 2019 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
  55. Elimination of damaged cells-dependent antiaging strategy
    Rayees Ahmad Naik, Vinodinee Dubey, Roshni Rajpoot, Debabrata Dash, Nidhi Gupta, Raj Kumar Koiri · 2022 · Elsevier eBooks
  56. Xeno-free generation of human induced pluripotent stem cells from donor-matched fibroblasts isolated from dermal and oral tissues
    Hassan R. W. Ali, Salwa Suliman, Tarig Osman, Manuel Carrasco, Ove Bruland, Daniela Elena Costea, Helge Ræder, Kamal Mustafa · 2023 · Research Square
  57. Additional file 6 of Altered neuronal physiology, development, and function associated with a common chromosome 15 duplication involving CHRNA7
    Kesavan Meganathan, Ramachandran Prakasam, Dustin Baldridge, Paul M. Gontarz, Bo Zhang, Fumihiko Urano, Azad Bonni, Susan E. Maloney, Tychele N. Turner, James E. Huettner et al. · 2021 · Figshare
  58. Additional file 13 of Altered neuronal physiology, development, and function associated with a common chromosome 15 duplication involving CHRNA7
    Kesavan Meganathan, Ramachandran Prakasam, Dustin Baldridge, Paul M. Gontarz, Bo Zhang, Fumihiko Urano, Azad Bonni, Susan E. Maloney, Tychele N. Turner, James E. Huettner et al. · 2021 · Figshare
  59. Additional file 5 of Altered neuronal physiology, development, and function associated with a common chromosome 15 duplication involving CHRNA7
    Kesavan Meganathan, Ramachandran Prakasam, Dustin Baldridge, Paul M. Gontarz, Bo Zhang, Fumihiko Urano, Azad Bonni, Susan E. Maloney, Tychele N. Turner, James E. Huettner et al. · 2021 · Figshare
  60. Additional file 10 of Altered neuronal physiology, development, and function associated with a common chromosome 15 duplication involving CHRNA7
    Kesavan Meganathan, Ramachandran Prakasam, Dustin Baldridge, Paul M. Gontarz, Bo Zhang, Fumihiko Urano, Azad Bonni, Susan E. Maloney, Tychele N. Turner, James E. Huettner et al. · 2021 · Figshare
  61. Additional file 4 of Altered neuronal physiology, development, and function associated with a common chromosome 15 duplication involving CHRNA7
    Kesavan Meganathan, Ramachandran Prakasam, Dustin Baldridge, Paul M. Gontarz, Bo Zhang, Fumihiko Urano, Azad Bonni, Susan E. Maloney, Tychele N. Turner, James E. Huettner et al. · 2021 · Figshare
  62. Additional file 8 of Altered neuronal physiology, development, and function associated with a common chromosome 15 duplication involving CHRNA7
    Kesavan Meganathan, Ramachandran Prakasam, Dustin Baldridge, Paul M. Gontarz, Bo Zhang, Fumihiko Urano, Azad Bonni, Susan E. Maloney, Tychele N. Turner, James E. Huettner et al. · 2021 · Figshare
  63. Additional file 2 of Xeno-free generation of human induced pluripotent stem cells from donor-matched fibroblasts isolated from dermal and oral tissues
    Hassan R. W. Ali, Salwa Suliman, Tarig Osman, Manuel Carrasco, Ove Bruland, Daniela Elena Costea, Helge Ræder, Kamal Mustafa · 2023 · Figshare
  64. Additional file 2 of Altered neuronal physiology, development, and function associated with a common chromosome 15 duplication involving CHRNA7
    Kesavan Meganathan, Ramachandran Prakasam, Dustin Baldridge, Paul M. Gontarz, Bo Zhang, Urano, Fumihiko, Azad Bonni, Susan E. Maloney, Tychele N. Turner, James E. Huettner et al. · 2021 · Figshare
  65. Additional file 3 of Altered neuronal physiology, development, and function associated with a common chromosome 15 duplication involving CHRNA7
    Kesavan Meganathan, Ramachandran Prakasam, Dustin Baldridge, Paul M. Gontarz, Bo Zhang, Urano, Fumihiko, Azad Bonni, Susan E. Maloney, Tychele N. Turner, James E. Huettner et al. · 2021 · Figshare
  66. Additional file 1 of Automating iPSC generation to enable autologous photoreceptor cell replacement therapy
    Laura R. Bohrer, Nicholas E. Stone, Nathaniel K. Mullin, Andrew P. Voigt, Kristin R. Anfinson, Jessica L. Fick, Viviane Luangphakdy, Bradley Hittle, Kimerly A. Powell, George F. Muschler et al. · 2024 · Figshare
  67. Additional file 9 of Altered neuronal physiology, development, and function associated with a common chromosome 15 duplication involving CHRNA7
    Kesavan Meganathan, Ramachandran Prakasam, Dustin Baldridge, Paul M. Gontarz, Bo Zhang, Urano, Fumihiko, Azad Bonni, Susan E. Maloney, Turner, Tychele N., James E. Huettner et al. · 2021 · Figshare
  68. Additional file 1 of Xeno-free generation of human induced pluripotent stem cells from donor-matched fibroblasts isolated from dermal and oral tissues
    Hassan R. W. Ali, Salwa Suliman, Osman, Tarig Al-Hadi, Manuel Carrasco, Ove Bruland, Costea, Daniela-Elena, Helge Ræder, Mustafa, Kamal · 2023 · Figshare
  69. Additional file 1 of Altered neuronal physiology, development, and function associated with a common chromosome 15 duplication involving CHRNA7
    Kesavan Meganathan, Ramachandran Prakasam, Dustin Baldridge, Paul M. Gontarz, Bo Zhang, Urano, Fumihiko, Azad Bonni, Susan E. Maloney, Tychele N. Turner, James E. Huettner et al. · 2021 · Figshare
  70. Additional file 11 of Altered neuronal physiology, development, and function associated with a common chromosome 15 duplication involving CHRNA7
    Kesavan Meganathan, Ramachandran Prakasam, Dustin Baldridge, Paul M. Gontarz, Bo Zhang, Urano, Fumihiko, Azad Bonni, Susan E. Maloney, Tychele N. Turner, James E. Huettner et al. · 2021 · Figshare
  71. Additional file 12 of Altered neuronal physiology, development, and function associated with a common chromosome 15 duplication involving CHRNA7
    Kesavan Meganathan, Ramachandran Prakasam, Dustin Baldridge, Paul M. Gontarz, Bo Zhang, Urano, Fumihiko, Azad Bonni, Susan E. Maloney, Tychele N. Turner, James E. Huettner et al. · 2021 · Figshare
  72. Additional file 14 of Altered neuronal physiology, development, and function associated with a common chromosome 15 duplication involving CHRNA7
    Kesavan Meganathan, Ramachandran Prakasam, Dustin Baldridge, Paul M. Gontarz, Bo Zhang, Urano, Fumihiko, Azad Bonni, Susan E. Maloney, Tychele N. Turner, James E. Huettner et al. · 2021 · Figshare
  73. Additional file 7 of Altered neuronal physiology, development, and function associated with a common chromosome 15 duplication involving CHRNA7
    Kesavan Meganathan, Ramachandran Prakasam, Dustin Baldridge, Paul M. Gontarz, Bo Zhang, Urano, Fumihiko, Azad Bonni, Susan E. Maloney, Tychele N. Turner, James E. Huettner et al. · 2021 · Figshare
  74. Multi-Omics Reprogramming Drives a Counterintuitive Reversal of Disease Susceptibility During Ageing
    A. Valdivieso, Léo Duperret, Bruno Petton, Gaëlle Courtay, Océane Romatif, Juliette Pouzadoux, Sylvain Henry, Andrei Turtoï, Ève Toulza, Arnaud Lagorce et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
  75. Développement d’un modèle d’étude du vieillissement tissulaire basé sur l’utilisation de cellules souches à pluripotence induite par reprogrammation cellulaire.
    Nafissa Aït-Hamou · 2016 · theses.fr (ABES)
  76. Génération de cellules souches pluripotentes induites de patients Alzheimer et production d'un modèle de culture en trois dimensions de neurones pour les recherches diagnostiques et thérapeutiques de la maladie d’Alzheimer
    Laura Auboyer · 2018 · theses.fr (ABES)
  77. Functional rejuvenation of endothelial cell aging by transient reprogramming
    Katrin Kalies, Kai Knoepp, Laura Hehl, Simon Guerlach, Laura Sandiano, Andreas Simm, Jochen Dutzmann, Daniel Sedding · 2026 · Basic Research in Cardiology
  78. Direct neuronal reprogramming by transdifferentiation and application of induced neurons
    Vaishnavi Anathanarayana, Tanu Suma Narayanappa, Subashchandrabose Chinnathambi · 2026 · Methods in enzymology on CD-ROM/Methods in enzymology
  79. Organoids in drug discovery and development: emerging technologies to transition beyond animal models
    Jolene Phelps, Amanda Orr, Stephanie Michelle Willerth · 2026 · Expert Opinion on Drug Discovery