Secretion of Wnt Ligands Requires Evi, a Conserved Transmembrane Protein
Bartscherer, Kerstin, Pelte, Nadège, Ingelfinger, Dierk, Boutros, Michael·2006·Cell
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- Brain transcriptome variation among behaviorally distinct strains of zebrafish (Danio rerio)Robert E Drew, Matthew Lee Settles, Erin Churchill, Shayna M. Williams-Burris, Soniya Balli, Barrie D. Robison · 2012 · BMC Genomics
- ERAD‐dependent control of the Wnt secretory factor EviKathrin Glaeser, Manuela B. Urban, Emma J. Fenech, Oksana Voloshanenko, Dominique Kranz, Federica Lari, John C. Christianson, Michael Boutros · 2018 · The EMBO Journal
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- Schisandrin A inhibits triple negative breast cancer cells by regulating Wnt/ER stress signaling pathwayXiaohong Xu, Vinothakumar Rajamanicham, Sujing Xu, Zhoudi Liu, Tao Yan, Guang Liang, Guilong Guo, Huiping Zhou, Yi Wang · 2019 · Biomedicine & Pharmacotherapy
- An RNAi screen identifies USP2 as a factor required for TNF‐α‐induced NF‐κB signalingMarie Oliver Metzig, Dorothee Nickles, Christina Falschlehner, Judith Lehmann‐Koch, Beate Katharina Straub, Wilfried Roth, Michael Boutros · 2011 · International Journal of Cancer
- Application of an integrated physical and functional screening approach to identify inhibitors of the Wnt pathwayBryan W Miller, Garnet Lau, Chris Grouios, Emanuela Mollica, Miriam Barrios‐Rodiles, Yongmei Liu, Alessandro Datti, Quaid Morris, Jeffrey L. Wrana, Liliana Attisano · 2009 · Molecular Systems Biology
- WlsProvides a New Compartmental View of the Rhombic Lip in Mouse Cerebellar DevelopmentJoanna Yeung, Thomas J Ha, Douglas J. Swanson, Kunho Choi, Yiai Tong, Dan Goldowitz · 2014 · Journal of Neuroscience
- Rab8a vesicles regulate Wnt ligand delivery and Paneth cell maturation at the intestinal stem cell nicheSoumyashree Das, Shiyan Yu, Ryotaro Sakamori, Pavan Vedula, Qiang Feng, Juan Flores, Andrew Hoffman, Jiang Fu, Ewa Stypulkowski, Alexis Rodriguez et al. · 2015 · Development
- WNT signalling events near the cell membrane and their pharmacological targeting for the treatment of cancerElse Driehuis, Hans C. Clevers · 2017 · British Journal of Pharmacology
- Loss of epidermal Evi/Wls results in a phenotype resembling psoriasiform dermatitisIris Augustin, Julia Christina Gross, Daniel Baumann, Claudia Korn, Gráinne Kerr, Tamara Grigoryan, Cornelia Mauch, Walter Birchmeier, Michael Boutros · 2013 · The Journal of Experimental Medicine
- Robust Wnt signaling is maintained by a Wg protein gradient and Fz2 receptor activity in the developing Drosophila wingVarun Chaudhary, Swapnil Hingole, Jana Frei, F. Port, D. Strutt, M. Boutros · 2019 · Development
- Wnt signal from multiple tissues and lin-3 /EGF signal from the gonad maintain vulval precursor cell competence in Caenorhabditis elegansToshia R. Myers, Iva Greenwald · 2007 · Proceedings of the National Academy of Sciences
- Drugging the Cancer Stem Cell Compartment: Lessons Learned from the Hedgehog and Wnt Signal Transduction PathwaysMichael E. Dodge, Lawrence Lum · 2011 · The Annual Review of Pharmacology and Toxicology
- WLS-Wnt signaling promotes neuroendocrine prostate cancerTyler Bland, Jing Wang, Lijuan Yin, Tianjie Pu, Jingjing Li, Jin Gao, Tzu-Ping Lin, Allen C. Gao, Boyang Jason Wu · 2020 · iScience
- The role of cnidarian developmental biology in unraveling axis formation and Wnt signalingThomas W. Holstein · 2022 · Developmental Biology
- β-catenin-independent regulation of Wnt target genes by RoR2 and ATF2/ATF4 in colon cancer cellsOksana Voloshanenko, Uwe Schwartz, Dominique Kranz, Benedikt Rauscher, Michael Linnebacher, Iris Augustin, Michael Boutros · 2018 · Scientific Reports
- A Human Pleiotropic Multiorgan Condition Caused by Deficient Wnt SecretionGuoliang Chai, Emmanuelle Szenker‐Ravi, Changuk Chung, Zhen Li, Lu Wang, Muznah Khatoo, Trevor G Marshall, Nan Jiang, Xiaoxu Yang, Jennifer McEvoy‐Venneri et al. · 2021 · New England Journal of Medicine
- Wnt Signaling in Cardiac DiseaseKevin C.M. Hermans, W. Matthijs Blankesteijn · 2015 · Comprehensive physiology
- Wnt Signaling Regulates Pulp Volume and Dentin ThicknessWon Hee Lim, Bo Liu, Du Cheng, Daniel J. Hunter, Zhendong A. Zhong, Daniel M. Ramos, Bart O. Williams, Paul Thomas Sharpe, Claire Bardet, Su‐Jung Mah et al. · 2013 · Journal of Bone and Mineral Research
- High‐throughput RNAi screening to dissect cellular pathways: A how‐to guideChristina Falschlehner, Sandra Steinbrink, Gerrit Erdmann, Michael Boutros · 2010 · Biotechnology Journal
- Wnt signaling in hydroid development: ectopic heads and giant buds induced by GSK-3beta inhibitorsWerner de Andrade Müller, Uri Frank A, Regina Teo, Ofer Mokady, Christina Guette, Günter Plickert · 2007 · The International Journal of Developmental Biology
- A Large-Scale RNAi Screen Identifies Deaf1 as a Regulator of Innate Immune Responses in DrosophilaDavid Kuttenkeuler, Nadège Pelte, Anan Ragab, Viola Gesellchen, Lena Schneider, Claudia Blass, Elin Axelsson, Wolfgang K. Huber, Michael Boutros · 2009 · Journal of Innate Immunity
- Peripheral nerve morphogenesis induced by scaffold micropatterningFederica Cerri, Luca Salvatore, Danish Memon, Filippo Martinelli Boneschi, Marta Madaghiele, Paola Brambilla, Ubaldo Del Carro, Carla Taveggia, Nilo Riva, Amelia Trimarco et al. · 2014 · Biomaterials
- PORCN Moonlights in a Wnt-Independent Pathway That Regulates Cancer Cell ProliferationTracy M. Covey, Simran Jeet Kaur, Tina Tan Ong, Kyle David Proffitt, Yonghui Wu, Patrick B. O. Tan, David M. Virshup · 2012 · PLoS ONE
- Wnt signalling requires MTM‐6 and MTM‐9 myotubularin lipid‐phosphatase function in Wnt‐producing cellsMarie Macůrková, Fillip Port, Martin Harterink, Konrad Basler, Hendrik C. Korswagen · 2010 · The EMBO Journal
- Oncogenic Functions of Secreted Frizzled-Related Protein 2 in Human Renal CancerSoichiro Yamamura, Kazumori Kawakami, Hiroshi Hirata, Koji Ueno, Sharanjot Saini, Shahana Majid, Rajvir Dahiya · 2010 · Molecular Cancer Therapeutics
- PDZRN3 destabilizes endothelial cell-cell junctions through a PKCζ-containing polarity complex to increase vascular permeabilityRaj Nayan Sewduth, Héléna Kovacic, Béatrice Jaspard‐Vinassa, Vincent Jecko, Thomas Wavasseur, Nicolas Fritsch, Mathieu Pernot, Sylvie Jeanningros, Étienne Roux, Pascale Dufourcq et al. · 2017 · Science Signaling
- Dissecting Wnt Signaling for Melanocyte Regulation during Wound HealingQi Sun, Piul S. Rabbani, Makoto Takeo, Soung-Hoon Lee, Chae Ho Lim, EN-Nekema Shandi Noel, Makoto Mark Taketo, Peggy S. Myung, Sarah E. Millar, Mayumi Ito · 2018 · Journal of Investigative Dermatology
- Stem Cells, Patterning and Regeneration in Planarians: Self-Organization at the Organismal ScaleJochen Christian Rink · 2018 · Methods in molecular biology
- Sailing with the Wnt: Charting the Wnt processing and secretion routeMagdalena Joanna Lorenowicz, Hendrik C. Korswagen · 2009 · Experimental Cell Research
- Development and migration of the C. elegans Q neuroblasts and their descendantsTeije Corneel Middelkoop, Hendrik C. Korswagen · 2014 · WormBook
- Genetic architecture of natural variation in visual senescence in DrosophilaMary Anna Carbone, Yamamoto Ah, Wen Huang, Rachel A. Lyman, Tess Brune Meadors, Ryoan Yamamoto, Robert R. H. Anholt, Trudy F. C. Mackay · 2016 · Proceedings of the National Academy of Sciences
- Wnt signaling in the heart fields: Variations on a common themeAdrián Ruiz‐Villalba, Stefan Hoppler, Maurice J.B. van den Hoff · 2015 · Developmental Dynamics
- Regulatory mechanisms of sclerostin expression during bone remodelingMasanori Koide, Yasuhiro Kobayashi · 2018 · Journal of Bone and Mineral Metabolism
- Wnt/β-Catenin signaling pathway in hepatocellular carcinoma: pathogenic role and therapeutic targetZekun Zhao, Tenglu Cui, Fengxian Wei, Zhiming Zhou, Yuan Sun, Chaofeng Gao, Xiaodong Xu, Huihan Zhang · 2024 · Frontiers in Oncology
- Live imaging of active fluorophore labelled Wnt proteinsTatjana Holzer, Katrin Liffers, Karolin Rahm, Benjamin Trageser, Suat Özbek, Dietmar Gradl · 2012 · FEBS Letters
- Differences in the secretion and transport of Wnt proteinsShinji Takada, Sayumi Fujimori, Takuma Shinozuka, Ritsuko Takada, Yusuke Mii · 2016 · The Journal of Biochemistry
- Epigenetic regulation of the Hedgehog and Wnt pathways in cancer.L. Wils, M. Bijlsma · 2018 · Critical reviews in oncology/hematology
- Distinct Requirements for Cranial Ectoderm and Mesenchyme-Derived Wnts in Specification and Differentiation of Osteoblast and Dermal ProgenitorsLawrence Henry Goodnough, Gregg J. Dinuoscio, James W. Ferguson, Trevor Williams, Richard A. Lang, Radhika P. Atit · 2014 · PLoS Genetics
- EpCAM+ Liver Cancer Stem-Like Cells Exhibiting Autocrine Wnt Signaling Potentially Originate in Cirrhotic PatientsRitu Khosla, Archana Rastogi, Gayatri Ramakrishna, Viniyendra Pamecha, Ashok Mukhopadhyay, Madavan Vasudevan, Shiv Kumar Sarin, Nirupma Trehanpati · 2017 · Stem Cells Translational Medicine
- Synaptic Activity-Regulated Wnt Signaling in Synaptic Plasticity, Glial Function and Chronic PainShao‐Jun Tang · 2014 · CNS & Neurological Disorders - Drug Targets
- Widespread Rewiring of Genetic Networks upon Cancer Signaling Pathway ActivationMaximilian Billmann, Varun Chaudhary, Mostafa F. ElMaghraby, Bernd Fischer, Michael Boutros · 2017 · Cell Systems
- Positional information specifies the site of organ regeneration and not tissue maintenance in planariansEric M. Hill, Christian P. Petersen · 2018 · eLife
- Flying at the head of the pack: Wnt biology in DrosophilaAmy Bejsovec · 2006 · Oncogene
- Endocytosis and Signaling during DevelopmentChristian Bökel, Michael Brand · 2014 · Cold Spring Harbor Perspectives in Biology
- Wnt Signaling: Role in Regulation of HaematopoiesisRam Babu Undi, Usha Gutti, Itishri Sahu, Shilpa Sarvothaman, Satya Ratan Pasupuleti, Ravinder Kandi, Ravi Kumar Gutti · 2015 · Indian Journal of Hematology and Blood Transfusion
- Wls Is Expressed in the Epidermis and Regulates Embryonic Hair Follicle Induction in MiceSixia Huang, Xuming Zhu, Yanfang Liu, Yixin Tao, Guoyin Feng, Lin He, Xizhi Guo, Gang Ma · 2012 · PLoS ONE
- Gpr177, a novel locus for bone mineral density and osteoporosis, regulates osteogenesis and chondrogenesis in skeletal developmentTakamitsu Maruyama, Ming Jiang, Wei Hsu · 2012 · Journal of Bone and Mineral Research
- Wnt Signaling in Adult Epithelial Stem Cells and CancerSi Hui Tan, Nick Barker · 2018 · Progress in molecular biology and translational science
- Osteogenesis and Bone RegenerationHaisheng Yang · 2019 · IntechOpen eBooks
- Molecular basis of Wnt biogenesis, secretion, and Wnt7-specific signalingQi, Xiaofeng, Hu, Qinli, Elghobashi-Meinhardt, Nadia, Long, Tao, Chen, Hongwen, Li, Xiaochun · 2023 · Cell
- Molecular dissection of Wnt3a-Frizzled8 interaction reveals essential and modulatory determinants of Wnt signaling activitySumit Kumar, Mihaela Žigman, Trushar R. Patel, Benjamin Trageser, Julia Christina Gross, Karolin Rahm, Michael Boutros, Dietmar Gradl, Herbert Steinbeißer, Thomas W. Holstein et al. · 2014 · BMC Biology
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- Mesenchymal TGF-βSignaling Orchestrates Dental Epithelial Stem Cell Homeostasis Through Wnt SignalingGuan Yang, Jian Zhou, Yan Teng, Jing Xie, Jingting Lin, Xizhi Guo, Yuanrong Gao, Miao He, Xiao Yi Yang, Songlin Wang · 2014 · Stem Cells
- Proteomics analyses of microvesicles released by Drosophila Kc167 and S2 cellsTim Koppen, Andreas Weckmann, Stefan Müller, Simon Staubach, Wilhelm Bloch, R. Jürgen Dohmen, Tilo Schwientek · 2011 · PROTEOMICS
- The Pathophysiology of Osteoporosis after Spinal Cord InjuryRamsha Shams, Kelsey P. Drasites, Vandana Zaman, Denise D Matzelle, Donald C. Shields, Dena P. Garner, Christopher J. Sole, Azizul Haque, Naren Lal Banik · 2021 · International Journal of Molecular Sciences
- Vertebrate Wnt5a – At the crossroads of cellular signallingSally L. Rogers, Steffen Scholpp · 2021 · Seminars in Cell and Developmental Biology
- Lipid-modified morphogens: functions of fatsJosefa Steinhauer, Jessica E. Treisman · 2009 · Current Opinion in Genetics & Development
- Wnt Signaling Directs Neuronal Polarity and Axonal GrowthEliana Stanganello, Eitan Erez Zahavi, Mithila Burute, Jasper Smits, Ingrid Jordens, Madelon M. Maurice, Lukas C. Kapitein, Casper C. Hoogenraad · 2019 · iScience
- TMEM132A, a Novel Wnt Signaling Pathway Regulator Through Wntless (WLS) InteractionBinbin Li, Lee Ann Niswander · 2020 · Frontiers in Cell and Developmental Biology
- A novel Wnt5a‐Frizzled4 signaling pathway mediates activity‐independent dendrite morphogenesis via the distal PDZ motif of Frizzled 4Wen-Jie Bian, Wanying Miao, Shunji He, Zong‐Fang Wan, Zhen‐Ge Luo, Xiang Yu · 2014 · Developmental Neurobiology
- Differential Palmit(e)oylation of Wnt1 on C93 and S224 Residues Has Overlapping and Distinct ConsequencesLisa M. Galli, Laura W. Burrus · 2011 · PLoS ONE
- Gpr177 regulates pulmonary vasculature developmentMing Zuo Jiang, Wei-Yao Ku, Jiang Fu, Stefan Offermanns, Wei Hsu, Jianwen Que · 2013 · Development
- Roles of WNT, NOTCH, and Hedgehog signaling in the differentiation and function of innate and innate-like lymphocytesJessica C. Kling, Antje Blumenthal · 2016 · Journal of Leukocyte Biology
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- Therapeutic Potential of Naturally Occurring Small Molecules to Target the Wnt/β-Catenin Signaling Pathway in Colorectal CancerLuiz Fernando Silva Oliveira, Danilo Predes, Helena L. Borges, José G. Abreu · 2022 · Cancers
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- Molecular Pharmacology of Class F Receptor ActivationPaweł Kozielewicz, Ainoleena Turku, Gunnar Schulte · 2019 · Molecular Pharmacology
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- The Targeting of Native Proteins to the Endoplasmic Reticulum-Associated Degradation (ERAD) Pathway: An Expanding Repertoire of Regulated SubstratesDeepa Kumari, Jeffrey L. Brodsky · 2021 · Biomolecules
- Expression of GPR177 (Wntless/Evi/Sprinter), a highly conserved Wnt‐transport protein, in rat tissues, zebrafish embryos, and cultured human cellsJay Jin, Megan Morse, Colleen Frey, Jessica Petko, Robert G. Levenson · 2010 · Developmental Dynamics
- The Function of Wnt Ligands on Osteocyte and Bone RemodelingDu, J.H., Lin, S.X., Wu, X.L., Yang, S.M., Cao, L.Y., Zheng, A., Wu, J.N., Jiang, X.Q. · 2019 · Journal of Dental Research
- Hepatic sinusoids versus central veins: Structures, markers, angiocrines, and roles in liver regeneration and homeostasisKi Mark Mak, Da Wi Shin · 2020 · The Anatomical Record
- Vertebrate Axial Patterning: From Egg to AsymmetryDouglas W. Houston · 2016 · Advances in experimental medicine and biology
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- Xenopus Wntless and the Retromer Complex Cooperate To Regulate XWnt4 SecretionHyunjoon Kim, Seong-Moon Cheong, Jihae Ryu, Hwajin Jung, Eek‐hoon Jho, Jin‐Kwan Han · 2009 · Molecular and Cellular Biology
- Expression of Gpr177, a Wnt trafficking regulator, in mouse embryogenesisHsiao‐Man Ivy Yu, Ying Jin, Jiang Fu, Wei Hsu · 2010 · Developmental Dynamics
- Drosophila p24 and Sec22 regulate Wingless trafficking in the early secretory pathwayXue Li, Yihui Wu, Chenghao Shen, Tatyana Y. Belenkaya, Lorraine Ray, Xinhua Lin · 2015 · Biochemical and Biophysical Research Communications
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- The Roles of Secreted Wnt Ligands in CancerJohannes Werner, Kim E. Boonekamp, Tianzuo Zhan, Michael Boutros · 2023 · International Journal of Molecular Sciences
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- Wnt signalling in mouse mesenchymal stem cells: impact on proliferation, invasion and MMP expressionMarisa Karow, Tanja Popp, Virginia Egea, Christian Ries, Marianne Jochum, Peter Neth · 2008 · Journal of Cellular and Molecular Medicine
- Adipose- and muscle-derived Wnts trigger pancreatic β-cell adaptation to systemic insulin resistanceKamil Koziński, Magdalena Jazurek, Paweł Dobrzyń, Justyna Janikiewicz, Katarzyna Kolczyńska, Anna Gajda, Agnieszka Dobrzyń · 2016 · Scientific Reports
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- Retromer-Mediated Trafficking of Transmembrane Receptors and TransportersStine Christensen Klinger, Piotr Siupka, Morten Schallburg Nielsen · 2015 · Membranes
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- A Wnt-Independent LGR4–EGFR Signaling Axis in Cancer MetastasisFei Yue, Weiyu Jiang, Amy Tsu Ku, Adelaide I.J. Young, Weijie Zhang, Eric P. Souto, Yankun Gao, Zihan Yu, Yi Wang, Chad J. Creighton et al. · 2021 · Cancer Research
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