Deregulation of Scribble Promotes Mammary Tumorigenesis and Reveals a Role for Cell Polarity in Carcinoma
Zhan, Lixing, Rosenberg, Avi, Bergami, Kenneth C., Yu, Min, Xuan, Zhenyu, Jaffe, Aron B., Allred, Craig, Muthuswamy, Senthil K.·2008·Cell
Cited by (436)
Items 401–436 of 436
- The cell adhesion receptor TMIGD1 recruits Scribble to the basolateral membrane via direct interactionKlaus Ebnet, Eva-Maria Thüring, Christian Hartmann, Janesha C. Maddumage, Airah Javorsky, Birgitta E. Michels, Volker Gerke, Lawrence Banks, Patrick Orson Humbert, Marc Kvansakul · 2023 · Research Square
- Data from Basal but not Luminal Mammary Epithelial Cells Require PI3K/mTOR Signaling for Ras-Driven OvergrowthKristin A. Plichta, Jessica L. Mathers, Shelley A. Gestl, Adam B. Glick, Edward J. Gunther · 2023
- Data from The Predominant WT1 Isoform (+KTS) Encodes a DNA-Binding Protein Targeting the Planar Cell Polarity Gene Scribble in Renal PodocytesJulie Wells, Miguel N. Rivera, Woo Jae Kim, Kristen D. Starbuck, Daniel A. Haber · 2023
- Data from The Predominant WT1 Isoform (+KTS) Encodes a DNA-Binding Protein Targeting the Planar Cell Polarity Gene Scribble in Renal PodocytesJulie Wells, Miguel N. Rivera, Woo Jae Kim, Kristen D. Starbuck, Daniel A. Haber · 2023
- Drug Resistance Mechanism of Tri-ple-Negative Breast Cancer and Research Progress with DLG5旭升 王 · 2023 · Advances in Clinical Medicine
- Polarity protein Par3L deletion causes chromosomal segregation defects and tumorigenesisWeili Zhang, Fengyan Dai, Yindan Hong, Chenyue Gao, Jiangchao Li, Lijun Dai, Yuxiang Liang, 義夫 田中, Yongliang Huo · 2025 · Journal of Biological Chemistry
- Interactions of the human papillomavirus E6 protein and their role in the persistence of viral episomesLietta Nicolaides · 2011 · UCL Discovery (University College London)
- HUGL and the Role of Polarity in Breast CancerAtlantis Dawn Russ · 2013 · UA Campus Repository (The University of Arizona)
- Additional file 1 of Integrative multi-omic sequencing reveals the MMTV-Myc mouse model mimics human breast cancer heterogeneityCarson D. Broeker, Mylena M.O. Ortiz, Murillo, Michael S., Eran R. Andrechek · 2023 · Figshare
- Additional file 2 of Integrative multi-omic sequencing reveals the MMTV-Myc mouse model mimics human breast cancer heterogeneityCarson D. Broeker, Mylena M.O. Ortiz, Murillo, Michael S., Eran R. Andrechek · 2024 · Figshare
- Le transporteur d’iode NIS dans la carcinogenèse non thyroïdienne : nouvelles fonctions, nouveaux enjeuxClaire Lacoste · 2011
- Caractérisation du récepteur de la polarité planaire Vangl2 dans les cancers du seinEdwige Belotti · 2010 · theses.fr (ABES)
- Cell polarity in hepatic cells physiopathologyLeila Akkari · 2010
- Rôle de Scribble1 dans la formation des synapses glutamatergiques et le trafic des récepteurs NMDANicolas H. Piguel · 2010 · theses.fr (ABES)
- Etude de la polarité apico-basale dans les cellules épithéliales et son implication dans le cholangiocarcinome intrahépatique : contribution de l'inositol 5-phosphatase SHIP2Ola Hamze komaiha · 2017
- The Scrib1 Interactome and its relevance for synaptic plasticity & neurodevelopmental disordersVera Lúcia Margarido Pinheiro · 2014 · theses.fr (ABES)
- Identification and functional characterization of a novel Scribble phosphorylation siteMônica Silveira Wagner · 2019 · theses.fr (ABES)
- Rôle de Lano/LRRC1 dans le cancer du sein et influence sur les cellules souches cancéreusesLéonor Lopez Almeida · 2017
- Understanding the synergy between Notch and the polarity determinant Scribble during neoplasiaRémi Logeay · 2017
- La souris humanisée : modèle d'étude in vivo du processus leucémogène induit par HTLV-1Éléonore Pérès · 2017 · theses.fr (ABES)
- Importance of AJ and cell polarity in the regulation of Fas signalingHala Awina · 2019 · theses.fr (ABES)
- L'oncogène aPKCi, nouvel acteur de la dissémination tumorale précoceClémentine Villeneuve · 2019
- Molecular and functional characterization of the PDZ-binding motif (PBM) of the planar cell polarity (PCP) VANGL2 proteinMarta Montserrat gomez · 2020 · theses.fr (ABES)
- Étude moléculaire et ciblage de la protéine de la polarité planaire VANGL2 dans les cancers du seinAlexandra Walton · 2020 · theses.fr (ABES)
- TGFβ Controls the Apico-Basolateral Orientation of Tumor Spheres and Is Correlated With Patient Outcome in Colorectal CancerCharlotte Canet-Jourdan · 2021
- Contrôle de l'évolution des tumeurs épithéliales par les propriétés mécaniques et la mort cellulaireMarianne Montemurro · 2023 · theses.fr (ABES)
- The Par complex regulates apical-basal cell polarity through modulation of FAK signaling homeostasisMeiai He, Lining Liang, Yulu Wang, Yongyu Chen, Han Sun, Lin Guo, Changpeng Li, Jingcai He, Yanhua Wu, Shiyu Chen et al. · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
- FGF21 suppresses hepatocellular carcinoma by driving competitive cell-cell interactionsMotoyuki Ogawa, Takao Fujisawa, Satoshi Takenaka, Mina Yano, Masafumi Kuroda, Daisuke Taniguchi, Ziwei Wang, Toru Hiratsuka, Akinori Kanai, Yutaka Suzuki et al. · 2026 · Cell Reports
- The Par complex regulates apical-basal cell polarity through modulation of FAK signaling homeostasisMeiai He, Lining Liang, Yue Wang, Yongyu Chen, Hao Sun, Lin Guo, Changpeng Li, Jingcai He, Yanhua Wu, Shiyu Chen et al. · 2026 · eLife
- The Par complex regulates apical-basal cell polarity through modulation of FAK signaling homeostasisMeiai He, Lining Liang, Yulu Wang, Yongyu Chen, Hao Sun, Lin Guo, Changpeng Li, Jingcai He, Yanhua Wu, Shiyu Chen et al. · 2026 · eLife
- A distinctive PDZ:β-hairpin interaction mediates AFDN complex with SCRIB and promotes binding to KRASChang Hwa Jo, Regina Strakhova, Marilyn Goudreault, Gabriela Bernal Astrain, Matthew James Smith · 2026 · Biochemical Journal
- Immunohistochemical and Molecular Analysis of Occludin, Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Catalytic Subunit Beta Isoform and Scribble Planar Cell Polarity Protein in Oral Squamous Cell Carcinoma Progression: A Three-Marker Exploratory StudyPriya Devi, Ayushi Jain, Ankit Sharma, Arushi Tomar, Priyanka Singh, Shalini Gupta · 2026 · Bratislavské lekárske listy/Bratislava medical journal
- LRRC1 promotes hepatocellular carcinoma progression via FASN-dependent reprogramming of lipid metabolismBo Ding, Junru Chen, Xinyu Xu, Kai Ni, Keyi Du, Beng Yang, Wendi Hu, Haiyang Xie, Shusen Zheng, Chaofeng Ding et al. · 2026 · Genes & Diseases
- Deficient NAT10-mediated ac4C modification destabilizes SCRIB mRNA and impairs endometrial decidualization in recurrent spontaneous abortionZhongjia Gu, Weixu Ma, Zhenping Yan, Yingyu Liang, Siying Lai, Luoyao Huang, Xinling Li, Mingxing Liu, Pei Xu, Han Lin et al. · 2026 · International Journal of Biological Macromolecules
- Role of the cJun NH2-Terminal Kinase (JNK) in Cancer: A DissertationCristina Cellurale · 2010 · eScholarship@UMassChan
- Scribble as a Possible Binding Partner for the MAP Kinases ERK2 and ERK6William R. Allen · 2009 · VCU Scholars Compass (Virginia Commonwealth University)