Deregulation of Scribble Promotes Mammary Tumorigenesis and Reveals a Role for Cell Polarity in Carcinoma

Zhan, Lixing, Rosenberg, Avi, Bergami, Kenneth C., Yu, Min, Xuan, Zhenyu, Jaffe, Aron B., Allred, Craig, Muthuswamy, Senthil K.·2008·Cell

Cited by (436)

Items 401–436 of 436

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  2. Data from Basal but not Luminal Mammary Epithelial Cells Require PI3K/mTOR Signaling for Ras-Driven Overgrowth
    Kristin A. Plichta, Jessica L. Mathers, Shelley A. Gestl, Adam B. Glick, Edward J. Gunther · 2023
  3. Data from The Predominant WT1 Isoform (+KTS) Encodes a DNA-Binding Protein Targeting the Planar Cell Polarity Gene Scribble in Renal Podocytes
    Julie Wells, Miguel N. Rivera, Woo Jae Kim, Kristen D. Starbuck, Daniel A. Haber · 2023
  4. Data from The Predominant WT1 Isoform (+KTS) Encodes a DNA-Binding Protein Targeting the Planar Cell Polarity Gene Scribble in Renal Podocytes
    Julie Wells, Miguel N. Rivera, Woo Jae Kim, Kristen D. Starbuck, Daniel A. Haber · 2023
  5. Drug Resistance Mechanism of Tri-ple-Negative Breast Cancer and Research Progress with DLG5
    旭升 王 · 2023 · Advances in Clinical Medicine
  6. Polarity protein Par3L deletion causes chromosomal segregation defects and tumorigenesis
    Weili Zhang, Fengyan Dai, Yindan Hong, Chenyue Gao, Jiangchao Li, Lijun Dai, Yuxiang Liang, 義夫 田中, Yongliang Huo · 2025 · Journal of Biological Chemistry
  7. Interactions of the human papillomavirus E6 protein and their role in the persistence of viral episomes
    Lietta Nicolaides · 2011 · UCL Discovery (University College London)
  8. HUGL and the Role of Polarity in Breast Cancer
    Atlantis Dawn Russ · 2013 · UA Campus Repository (The University of Arizona)
  9. Additional file 1 of Integrative multi-omic sequencing reveals the MMTV-Myc mouse model mimics human breast cancer heterogeneity
    Carson D. Broeker, Mylena M.O. Ortiz, Murillo, Michael S., Eran R. Andrechek · 2023 · Figshare
  10. Additional file 2 of Integrative multi-omic sequencing reveals the MMTV-Myc mouse model mimics human breast cancer heterogeneity
    Carson D. Broeker, Mylena M.O. Ortiz, Murillo, Michael S., Eran R. Andrechek · 2024 · Figshare
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  12. Caractérisation du récepteur de la polarité planaire Vangl2 dans les cancers du sein
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  13. Cell polarity in hepatic cells physiopathology
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  14. Rôle de Scribble1 dans la formation des synapses glutamatergiques et le trafic des récepteurs NMDA
    Nicolas H. Piguel · 2010 · theses.fr (ABES)
  15. Etude de la polarité apico-basale dans les cellules épithéliales et son implication dans le cholangiocarcinome intrahépatique : contribution de l'inositol 5-phosphatase SHIP2
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  16. The Scrib1 Interactome and its relevance for synaptic plasticity & neurodevelopmental disorders
    Vera Lúcia Margarido Pinheiro · 2014 · theses.fr (ABES)
  17. Identification and functional characterization of a novel Scribble phosphorylation site
    Mônica Silveira Wagner · 2019 · theses.fr (ABES)
  18. Rôle de Lano/LRRC1 dans le cancer du sein et influence sur les cellules souches cancéreuses
    Léonor Lopez Almeida · 2017
  19. Understanding the synergy between Notch and the polarity determinant Scribble during neoplasia
    Rémi Logeay · 2017
  20. La souris humanisée : modèle d'étude in vivo du processus leucémogène induit par HTLV-1
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  21. Importance of AJ and cell polarity in the regulation of Fas signaling
    Hala Awina · 2019 · theses.fr (ABES)
  22. L'oncogène aPKCi, nouvel acteur de la dissémination tumorale précoce
    Clémentine Villeneuve · 2019
  23. Molecular and functional characterization of the PDZ-binding motif (PBM) of the planar cell polarity (PCP) VANGL2 protein
    Marta Montserrat gomez · 2020 · theses.fr (ABES)
  24. Étude moléculaire et ciblage de la protéine de la polarité planaire VANGL2 dans les cancers du sein
    Alexandra Walton · 2020 · theses.fr (ABES)
  25. TGFβ Controls the Apico-Basolateral Orientation of Tumor Spheres and Is Correlated With Patient Outcome in Colorectal Cancer
    Charlotte Canet-Jourdan · 2021
  26. Contrôle de l'évolution des tumeurs épithéliales par les propriétés mécaniques et la mort cellulaire
    Marianne Montemurro · 2023 · theses.fr (ABES)
  27. The Par complex regulates apical-basal cell polarity through modulation of FAK signaling homeostasis
    Meiai He, Lining Liang, Yulu Wang, Yongyu Chen, Han Sun, Lin Guo, Changpeng Li, Jingcai He, Yanhua Wu, Shiyu Chen et al. · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
  28. FGF21 suppresses hepatocellular carcinoma by driving competitive cell-cell interactions
    Motoyuki Ogawa, Takao Fujisawa, Satoshi Takenaka, Mina Yano, Masafumi Kuroda, Daisuke Taniguchi, Ziwei Wang, Toru Hiratsuka, Akinori Kanai, Yutaka Suzuki et al. · 2026 · Cell Reports
  29. The Par complex regulates apical-basal cell polarity through modulation of FAK signaling homeostasis
    Meiai He, Lining Liang, Yue Wang, Yongyu Chen, Hao Sun, Lin Guo, Changpeng Li, Jingcai He, Yanhua Wu, Shiyu Chen et al. · 2026 · eLife
  30. The Par complex regulates apical-basal cell polarity through modulation of FAK signaling homeostasis
    Meiai He, Lining Liang, Yulu Wang, Yongyu Chen, Hao Sun, Lin Guo, Changpeng Li, Jingcai He, Yanhua Wu, Shiyu Chen et al. · 2026 · eLife
  31. A distinctive PDZ:β-hairpin interaction mediates AFDN complex with SCRIB and promotes binding to KRAS
    Chang Hwa Jo, Regina Strakhova, Marilyn Goudreault, Gabriela Bernal Astrain, Matthew James Smith · 2026 · Biochemical Journal
  32. Immunohistochemical and Molecular Analysis of Occludin, Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Catalytic Subunit Beta Isoform and Scribble Planar Cell Polarity Protein in Oral Squamous Cell Carcinoma Progression: A Three-Marker Exploratory Study
    Priya Devi, Ayushi Jain, Ankit Sharma, Arushi Tomar, Priyanka Singh, Shalini Gupta · 2026 · Bratislavské lekárske listy/Bratislava medical journal
  33. LRRC1 promotes hepatocellular carcinoma progression via FASN-dependent reprogramming of lipid metabolism
    Bo Ding, Junru Chen, Xinyu Xu, Kai Ni, Keyi Du, Beng Yang, Wendi Hu, Haiyang Xie, Shusen Zheng, Chaofeng Ding et al. · 2026 · Genes & Diseases
  34. Deficient NAT10-mediated ac4C modification destabilizes SCRIB mRNA and impairs endometrial decidualization in recurrent spontaneous abortion
    Zhongjia Gu, Weixu Ma, Zhenping Yan, Yingyu Liang, Siying Lai, Luoyao Huang, Xinling Li, Mingxing Liu, Pei Xu, Han Lin et al. · 2026 · International Journal of Biological Macromolecules
  35. Role of the cJun NH2-Terminal Kinase (JNK) in Cancer: A Dissertation
    Cristina Cellurale · 2010 · eScholarship@UMassChan
  36. Scribble as a Possible Binding Partner for the MAP Kinases ERK2 and ERK6
    William R. Allen · 2009 · VCU Scholars Compass (Virginia Commonwealth University)