Deregulation of Scribble Promotes Mammary Tumorigenesis and Reveals a Role for Cell Polarity in Carcinoma

Zhan, Lixing, Rosenberg, Avi, Bergami, Kenneth C., Yu, Min, Xuan, Zhenyu, Jaffe, Aron B., Allred, Craig, Muthuswamy, Senthil K.·2008·Cell

DOI 10.1016/j.cell.2008.09.045

Cited by (436)

Items 101–200 of 436

Tumor suppressor scribble regulates assembly of tight junctions in the intestinal epithelium
Ivanov, Andrei I., Young, Cheryl, Beste, Kyle Den, Capaldo, Christopher T., Humbert, Patrick O., Brennwald, Patrick, Parkos, Charles A., Nusrat, Asma · 2010 · The American Journal of Pathology
Analysis of Multiple HPV E6 PDZ Interactions Defines Type-Specific PDZ Fingerprints That Predict Oncogenic Potential
Miranda Thomas, Michael P. Myers, Paola Massimi, Corrado Guarnaccia, Lawrence Banks · 2016 · PLoS Pathogens
The planar polarity protein Scribble1 is essential for neuronal plasticity and brain function
Moreau, M. M., Piguel, N., Papouin, T., Koehl, M., Durand, C. M., Rubio, M. E., Loll, F., Richard, E. M., Mazzocco, C., Racca, C. et al. · 2010 · Journal of Neuroscience
The role of TGF-β and its crosstalk with RAC1/RAC1b signaling in breast and pancreas carcinoma
Catharina Melzer, Ralf Hass, Juliane von der Ohe, Hendrik Lehnert, Hendrik Ungefroren · 2017 · Cell Communication and Signaling
An interaction between Scribble and the NADPH oxidase complex controls M1 macrophage polarization and function
Zheng, Weiyue, Umitsu, Masataka, Jagan, Ishaan, Tran, Charles W., Ishiyama, Noboru, BeGora, Michael, Araki, Kiyomi, Ohashi, Pamela S., Ikura, Mitsuhiko, Muthuswamy, Senthil K. · 2016 · Nature Cell Biology
Junctional Adhesion Molecules in Cancer: A Paradigm for the Diverse Functions of Cell–Cell Interactions in Tumor Progression
Lauko, Adam, Mu, Zhaomei, Gutmann, David H., Naik, Ulhas P., Lathia, Justin D. · 2020 · Cancer Research
Hepatitis C viral protein NS5A induces EMT and participates in oncogenic transformation of primary hepatocyte precursors
Leila Akkari, Damien Grégoire, Nicolas Floc’h, Marie Moreau, Céline Hernandez, Yannick Simonin, Arielle R. Rosenberg, Patrice Lassus, Urszula Hibner · 2012 · Journal of Hepatology
Zebrafish neural tube morphogenesis requires Scribble-dependent oriented cell divisions
Žigman, Mihaela, Trinh, Le A., Fraser, Scott E., Moens, Cecilia B. · 2011 · Current Biology
Roles of Cadherins and Catenins in Cell−Cell Adhesion and Epithelial Cell Polarity
William James Nelson, Daniel J. Dickinson, William I. Weis · 2013 · Progress in molecular biology and translational science
The Cdc42/Par6/aPKC Polarity Complex Regulates Apoptosis-Induced Compensatory Proliferation in Epithelia
Stephen J. Warner, Hanako Yashiro, Gregory D. Longmore · 2010 · Current Biology
The protein kinase Pak4 disrupts mammary acinar architecture and promotes mammary tumorigenesis
Yingchao Liu, Ning Chen, Xinge Cui, Xi Zheng, L Deng, S Price, Vassiliki Karantza, Audrey Minden · 2010 · Oncogene
Cell competition: Emerging mechanisms to eliminate neighbors
Rina Nagata, Tatsushi Igaki · 2018 · Development Growth & Differentiation
Loss of DLG5 promotes breast cancer malignancy by inhibiting the Hippo signaling pathway
Liu, Jie, Li, Juan, Li, Pingping, Wang, Yaochun, Liang, Zheyong, Jiang, Yina, Li, Jing, Feng, Chen, Wang, Ruiqi, Chen, He et al. · 2017 · Scientific Reports
Physical stimuli-emitting scaffolds: The role of piezoelectricity in tissue regeneration
Carmen Alvarez‐Lorenzo, Mariana Zarur, Alejandro Seijo-Rabina, Bárbara Blanco‐Fernandez, Isabel Rodríguez‐Moldes, Ángel Concheiro · 2023 · Materials Today Bio
Human tumour viruses and the deregulation of cell polarity in cancer
Lawrence Banks, David Pim, Miranda Thomas · 2012 · Nature reviews. Cancer
The Human PDZome: A Gateway to PSD95-Disc Large-Zonula Occludens (PDZ)-mediated Functions
Edwige Belotti, Jolanta Polanowska, Avais M. Daulat, Stéphane Audebert, Virginie Thomé, Jean‐Claude Lissitzky, Frédérique Lembo, Karim Blibek, Shizue Omi, Nicolas Lenfant et al. · 2013 · Molecular & Cellular Proteomics
The Scribble family in cancer: twentieth anniversary
Santoni, Marie-Josée, Kashyap, Rudra, Camoin, Luc, Borg, Jean-Paul · 2020 · Oncogene
Reinterpreting polarity and cancer: The changing landscape from tumor suppression to tumor promotion
Yasuhiro Saito, Ridhdhi Desai, Senthil K. Muthuswamy · 2018 · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
Polarity Protein Complex Scribble/Lgl/Dlg And Epithelial Cell Barriers
Wen-Hui Su, Dolores D. Mruk, Elissa W.P. Wong, Wing‐Yee Lui, C. Yan Cheng · 2013 · Advances in experimental medicine and biology
Caveolar domain organization and trafficking is regulated by Abl kinases and mDia1
Asier Echarri, Olivia Muriel, Dácil María Pavón, Hind Azegrouz, Fernando Escolar, María Carmen Terrón, Fátima Sánchez‐Cabo, Fernando Martínez, Marı́a C. Montoya, Óscar Llorca et al. · 2012 · Journal of Cell Science
Roles for the Conserved Spc105p/Kre28p Complex in Kinetochore-Microtubule Binding and the Spindle Assembly Checkpoint
Cinzia Pagliuca, Viji M. Draviam, Eugenio Marco, Peter Karl Sorger, Peter De Wulf · 2009 · PLoS ONE
K-Ras and B-Raf oncogenes inhibit colon epithelial polarity establishment through up-regulation of c-myc
Kirti A. Magudia, Aurelia Lahoz, Alan Hall · 2012 · The Journal of Cell Biology
EZH2-Mediated Downregulation of the Tumor Suppressor DAB2IP Maintains Ovarian Cancer Stem Cells
Xingyue Zong, Weini Wang, Ali Özeş, Fang Fang, George Earl Sandusky, Kenneth P. Nephew · 2020 · Cancer Research
Scrib heterozygosity predisposes to lung cancer and cooperates with KRas hyperactivation to accelerate lung cancer progression in vivo
Elsum, I A, Yates, L L, Pearson, H B, Phesse, T J, Long, F, O'Donoghue, R, Ernst, M, Cullinane, C, Humbert, P O · 2014 · Oncogene
Cell polarity changes in cancer initiation and progression
Florent Péglion, Sandrine Etienne‐Manneville · 2023 · The Journal of Cell Biology
The planar cell polarity pathway in vertebrate development
Carolien Wansleeben, Frits C. P. W. Meijlink · 2011 · Developmental Dynamics
Progressive polarity loss and luminal collapse disrupt tissue organization in carcinoma
Ruba Halaoui, Carlis A. Rejon, Sudipa June Chatterjee, Joseph Szymborski, Sarkis H. Meterissian, William J. Muller, Atilla Ömeroğlu, Luke Martin McCaffrey · 2017 · Genes & Development
Scribble modulates the MAPK/Fra1 pathway to disrupt luminal and ductal integrity and suppress tumour formation in the mammary gland
Godde, Nathan J., Sheridan, Julie M., Smith, Lorey K., Pearson, Helen B., Britt, Kara L., Galea, Ryan C., Yates, Laura L., Visvader, Jane E., Humbert, Patrick O. · 2014 · PLoS Genetics
Normal morphogenesis of epithelial tissues and progression of epithelial tumors
Chun‐Chao Wang, Leen Jamal, Kevin A. Janes · 2011 · WIREs Systems Biology and Medicine
Muscle Stem Cell Fate Is Controlled by the Cell-Polarity Protein Scrib
Yusuke Ono, Yoshishige Urata, Shinji Goto, Shunsuke Nakagawa, Patrick Orson Humbert, Tao‐Sheng Li, Peter S. Zammit · 2015 · Cell Reports
Aberrant Overexpression of the Cell Polarity Module Scribble in Human Cancer
Valentina Vaira, Alice Faversani, Takehiko Dohi, Marco Maggioni, Mario Nosotti, Delfina Tosi, Dario C. Altieri, Silvano Bòsari · 2011 · American Journal Of Pathology
Tissue Polarity-Dependent Control of Mammary Epithelial Homeostasis and Cancer Development: an Epigenetic Perspective
Sophie A. Lelièvre · 2010 · Journal of Mammary Gland Biology and Neoplasia
Metformin suppresses proliferation and invasion of drug‐resistant breast cancer cells by activation of the Hippo pathway
Jie Liu, Juan Li, He Chen, Ruiqi Wang, Pingping Li, Yi Miao, Peijun Liu · 2020 · Journal of Cellular and Molecular Medicine
Developmental stratification of the mammary epithelium occurs through symmetry-breaking vertical divisions of apically positioned luminal cells
Robert J. Huebner, Terry Lechler, Andrew J. Ewald · 2014 · Development
Sleeping Beauty and the Microenvironment Enchantment: Microenvironmental Regulation of the Proliferation-Quiescence Decision in Normal Tissues and in Cancer Development
Ana Paula Zen Petisco Fiore, Pedro de Freitas Ribeiro, Alexandre Bruni‐Cardoso · 2018 · Frontiers in Cell and Developmental Biology
Aberrant Splicing of Hugl-1 Is Associated with Hepatocellular Carcinoma Progression
Xuefeng Lü, Xiujing Feng, Xiaobo Man, Guang Yang, Liang Tang, Dan Du, Fan Zhang, Hai‐Xin Yuan, Qin Huang, Zhe Zhang et al. · 2009 · Clinical Cancer Research
Loss of Scribble confers cisplatin resistance during NSCLC chemotherapy via Nox2/ROS and Nrf2/PD-L1 signaling
Na Wang, Lele Song, Yi Xu, Longfu Zhang, Yanjun Wu, Jingyu Guo, Weiwei Ji, Li Li, Jingya Zhao, Xin Zhang et al. · 2019 · EBioMedicine
The cytologic criteria of malignancy
Andrew H. Fischer, Chengquan Zhao, Qing Kay Li, Karen S. Gustafson, Isam-Eldin A. Eltoum, Rosemary Tambouret, Barbara D. Benstein, Lynnette C. Savaloja, Peter Kulesza · 2010 · Journal of Cellular Biochemistry
Cell Adhesion and Transcriptional Activity — Defining the Role of the Novel Protooncogene LPP
Thomas G. P. Grünewald, Saskia M. Pasedag, Elke Butt · 2009 · Translational Oncology
Putting into Practice Domain-Linear Motif Interaction Predictions for Exploration of Protein Networks
Katja Luck, Sadek Fournane, Bruno Kieffer, Murielle Masson, Yves Nominé, Gilles Travé · 2011 · PLoS ONE
Noncoding RNAs in breast cancer
Pang‐Kuo Lo, Benjamin Wolfson, Xipeng Zhou, Nadire Duru, Ramkishore Gernapudi, Qun Yong Zhou · 2015 · Briefings in Functional Genomics
Role of the polarity protein Scribble for podocyte differentiation and maintenance
Hartleben, Björn, Widmeier, Eugen, Wanner, Nicola, Schmidts, Miriam, Kim, Sung Tae, Schneider, Lisa, Mayer, Britta, Kerjaschki, Dontscho, Miner, Jeffrey H., Walz, Gerd et al. · 2012 · PLoS ONE
Emerging role of cell polarity proteins in breast cancer progression and metastasis
Luke Martin McCaffrey, Sudipa June Chatterjee · 2014 · Breast Cancer Targets and Therapy
Regulation of actin dynamics and protein trafficking during spermatogenesis – Insights into a complex process
Wenhui Su, Dolores D. Mruk, C. Yan Cheng · 2013 · Critical Reviews in Biochemistry and Molecular Biology
Cell polarity in morphogenesis and metastasis
Ian G. Macara, Luke Martin McCaffrey · 2013 · Philosophical Transactions of the Royal Society B Biological Sciences
Scrib is required for epithelial cell identity and prevents epithelial to mesenchymal transition in the mouse
Yamben, Idella F., Rachel, Rivka A., Shatadal, Shalini, Copeland, Neal G., Jenkins, Nancy A., Warming, Soren, Griep, Anne E. · 2013 · Developmental Biology
CRKL regulates alternative splicing of cancer-related genes in cervical cancer samples and HeLa cell
Qingling Song, Fengtao Yi, Yuhong Zhang, Daniel K. Jun Li, Yaxun Wei, Han Yu, Yi Zhang · 2019 · BMC Cancer
Label-Free Analysis of Breast Tissue Polarity by Raman Imaging of Lipid Phase
Shuhua Yue, Juan Manuel Cárdenas-Mora, Lesley S. Chaboub, Sophie A. Lelièvre, Ji‐Xin Cheng · 2012 · Biophysical Journal
Roles of the PDZ ‐binding motif of HPV 16 E6 protein in oncogenic transformation of human cervical keratinocytes
Yuki Yoshimatsu, Tomomi Nakahara, Katsuyuki Tanaka, 悠紀稲川, Mako Narisawa‐Saito, Takashi Yugawa, Shinichi Ohno, Masatoshi Fujita, Hitoshi Nakagama, Tohru Kiyono · 2017 · Cancer Science
Proteome profiling of triple negative breast cancer cells overexpressing NOD1 and NOD2 receptors unveils molecular signatures of malignant cell proliferation
Fernando Janczur Velloso, Alexandre Rosa Campos, Mari Cleide Sogayar, Ricardo G. Correa · 2019 · BMC Genomics
Tracking cells in epithelial acini by light sheet microscopy reveals proximity effects in breast cancer initiation
Ashna Alladin, Lucas Martins Chaible, Lucia Garcia del Valle, Sabine Reither, Monika Löschinger, Malte Wachsmuth, Jean-Karim Hèriché, Christian Tischer, Martin Jechlinger · 2020 · eLife
CDC42 controlled apical-basal polarity regulates intestinal stem cell to transit amplifying cell fate transition via YAP-EGF-mTOR signaling
Zheng Zhang, Feng Zhang, Ashley Kuenzi Davis, Mei Xin, Gerd Walz, Weidong Tian, Yi Zheng · 2022 · Cell Reports
Polarity proteins as regulators of cell junction complexes: Implications for breast cancer
Dana Bazzoun, Sophie A. Lelièvre, Rabih Talhouk · 2013 · Pharmacology & Therapeutics
Context dependent reversion of tumor phenotype by connexin-43 expression in MDA-MB231 cells and MCF-7 cells: Role of β-catenin/connexin43 association
Rabih Talhouk, Mohamed-Bilal Fares, Gilbert J. Rahme, Hanaa H. Hariri, Tina El Rayes, Hashem A. Dbouk, Dana Bazzoun, Dania Al Labban, Marwan Eid El-Sabban · 2013 · Experimental Cell Research
The cJUN NH2-terminal kinase (JNK) signaling pathway promotes genome stability and prevents tumor initiation
Nomeda Girnius, Yvonne J. K. Edwards, David S. Garlick, Roger J. Davis · 2018 · eLife
Endothelial Cell Migration and Vascular Endothelial Growth Factor Expression Are the Result of Loss of Breast Tissue Polarity
Amy Yen-Chi Chen, Ileana Cuevas, Paraic A. Kenny, Hiroshi Miyake, Kimberley Mace, Cyrus Michael Ghajar, Aaron Boudreau, Mina J. Bissell, Nancy J. Boudreau · 2009 · Cancer Research
Loss of Scribble Promotes Snail Translation through Translocation of HuR and Enhances Cancer Drug Resistance
Yi Zhou, Renxu Chang, Weiwei Ji, Na Wang, Meiyan Qi, Yi Xu, Jingyu Guo, Lixing Zhan · 2015 · Journal of Biological Chemistry
Defining the role of TRIP6 in cell physiology and cancer
Semjon Manuel Willier, Elke Butt, Günther H.S. Richter, Stefan E.G. Burdach, Thomas G. P. Grünewald · 2011 · Biology of the Cell
p120-catenin is essential for terminal end bud function and mammary morphogenesis
Sarah J. Kurley, Brian Bierie, Robert H. Carnahan, Nichole A. Lobdell, Michael A. Davis, Ilse Hofmann, Harold L. Moses, William J. Muller, Albert B. Reynolds · 2012 · Development
DEAR1 Is a Dominant Regulator of Acinar Morphogenesis and an Independent Predictor of Local Recurrence-Free Survival in Early-Onset Breast Cancer
Steven T. Lott, Nanyue Chen, Dawn S. Chandler, Qifeng Yang, Luo Wang, Marivonne Rodriguez, Hongyan Xie, Seetharaman Balasenthil, Thomas A. Buchholz, Ayşegül A. Şahin et al. · 2009 · PLoS Medicine
FRA-1 as a Regulator of EMT and Metastasis in Breast Cancer
Laura Casalino, Francesco Talotta, Ilenia Matino, Pasquale Verde · 2023 · International Journal of Molecular Sciences
Profiling and inhibiting reversible palmitoylation
Jeannie L. Hernandez, Jaimeen D. Majmudar, Brent R. Martin · 2012 · Current Opinion in Chemical Biology
miR-296/Scribble axis is deregulated in human breast cancer and miR-296 restoration reduces tumour growth in vivo
Federica Savi, Irene Forno, Alice Faversani, Andrea Luciani, S. Caldiera, Stefano Gatti, Paolo Foa, Dario Ricca, Gaetano Bulfamante, Valentina Vaira et al. · 2014 · Clinical Science
SCRIB Promotes Proliferation and Metastasis by Targeting Hippo/YAP Signalling in Colorectal Cancer
Hengyang Shen, Changzhi Huang, Jingyu Wu, Jie Li, Tao Hu, Zhenling Wang, Hongqiang Zhang, Yu Shao, Zan Fu · 2021 · Frontiers in Cell and Developmental Biology
Intramitochondrial Src kinase links mitochondrial dysfunctions and aggressiveness of breast cancer cells
Marie‐Ange Djeungoue‐Petga, Olivier Lurette, Stéphanie Jean, Geneviève Hamel-Côté, Rebeca Martín-Jiménez, Marine Bou, Astrid Cannich, Patrick Roy, Étienne Hébert-Chatelain · 2019 · Cell Death and Disease
Expression of Polarity Genes in Human Cancer
Wan‐Hsin Lin, Yan W. Asmann, Panos Z. Anastasiadis · 2015 · Cancer Informatics
A novel role for 14–3–3σ in regulating epithelial cell polarity
Chen Ling, Dongmei Zuo, Bin Xue, Senthil K. Muthuswamy, William J. Muller · 2010 · Genes & Development
CD74-dependent deregulation of the tumor suppressor Scribble in human epithelial and breast cancer cells
Metodieva, Gergana, Nogueira-de-Souza, Naiara Correa, Greenwood, Christina, Al-Janabi, Khalid, Leng, Lin, Bucala, Richard, Metodiev, Metodi V · 2013 · Neoplasia
Differential expression of PDZ domain‐containing proteins in human diseases – challenging topics and novel issues
Florencia Facciuto, Ana Laura Cavatorta, Marina Bugnon Valdano, Federico Marziali, Daniela Gardiol · 2012 · FEBS Journal
The cell polarity protein Scrib functions as a tumor suppressor in liver cancer
Shweta Kapil, Bal Krishan Sharma, Mallikarjun Patil, Sawsan Elattar, Jinling Yuan, Xianyu Steven Hou, Ravindra B Kolhe, Satyanarayana Ande · 2017 · Oncotarget
Loss of MMP-8 in ductal carcinoma in situ (DCIS)-associated myoepithelial cells contributes to tumour promotion through altered adhesive and proteolytic function
Müge Sarper, Michael D. Allen, Jenny Gomm, Linda Haywood, Julie V. Decock, Sally Thirkettle, Ahsen Ustaoglu, Shah‐Jalal Sarker, John F. Marshall, Dylan R. Edwards et al. · 2017 · Breast Cancer Research
The polarity protein Scrib mediates epidermal development and exerts a tumor suppressive function during skin carcinogenesis
Pearson, Helen B., McGlinn, Edwina, Phesse, Toby J., Schlüter, Holger, Srikumar, Anuratha, Gödde, Nathan J., Woelwer, Christina B., Ryan, Andrew, Phillips, Wayne A., Ernst, Matthias et al. · 2015 · Molecular Cancer
Genomic and epigenomic analysis of high-risk prostate cancer reveals changes in hydroxymethylation and TET1
Lien Spans, Thomas Van den Broeck, Elien Smeets, Stefan Preković, Bernard Thienpont, Diether Lambrechts, Robert Jeffrey Karnes, Nicholas Erho, Mohammed Alshalalfa, Elai Davicioni et al. · 2016 · Oncotarget
RasV12; scrib−/− Tumors: A Cooperative Oncogenesis Model Fueled by Tumor/Host Interactions
Dillard, Caroline, Reis, José Gerardo Teles, Rusten, Tor Erik · 2021 · International Journal of Molecular Sciences
PKCζ regulates cell polarisation and proliferation restriction during mammary acinus formation
Jacqueline Whyte, Laura Thornton, Sara McNally, Sarah S. McCarthy, Fiona T. Lanigan, William M. Gallagher, Torsten Stein, Finian Martin · 2010 · Journal of Cell Science
Nutrient-Dependent Changes of Protein Palmitoylation: Impact on Nuclear Enzymes and Regulation of Gene Expression
Matteo Spinelli, Salvatore Fusco, Claudio Grassi · 2018 · International Journal of Molecular Sciences
Mechanism of tumor‐suppressive cell competition in flies
Hiroshi Kanda, Tatsushi Igaki · 2020 · Cancer Science
Oriented cell division in vertebrate embryogenesis
Irinka Castanon, Marcos González‐Gaitán · 2011 · Current Opinion in Cell Biology
Loss of GM130 in breast cancer cells and its effects on cell migration, invasion and polarity
Francesco Baschieri, Edith Uetz-von Allmen, Daniel F. Legler, Hesso Farhan · 2015 · Cell Cycle
Structural basis for the differential interaction of Scribble PDZ domains with the guanine nucleotide exchange factor β-PIX
Lim, Krystle Y.B., Gödde, Nathan J., Humbert, Patrick O., Kvansakul, Marc · 2017 · Journal of Biological Chemistry
Modelling Cooperative Tumorigenesis in Drosophila
Helena E. Richardson, Marta Portela · 2018 · BioMed Research International
Deficiency of Erbin induces resistance of cervical cancer cells to anoikis in a STAT3-dependent manner
Y Hu, H Chen, Chenyang Duan, D Liu, Qian Lü, Zhengyan Yang, Liang Guo, Lina Song, M Yu, Meiqin Hu et al. · 2013 · Oncogenesis
NOS1AP Functionally Associates with YAP To Regulate Hippo Signaling
Leanne Clattenburg, Michael Wigerius, Jiansong Qi, Jan K. Rainey, Jillian L. Rourke, Shanmugam Muruganandan, Christopher J. Sinal, James P. Fawcett · 2015 · Molecular and Cellular Biology
Maximum Entropy Reconstructions of Dynamic Signaling Networks from Quantitative Proteomics Data
Jason W. Locasale, Alejandro Wolf‐Yadlin · 2009 · PLoS ONE
Structural centrosome aberrations favor proliferation by abrogating microtubule-dependent tissue integrity of breast epithelial mammospheres
Dominik Schnerch, Erich A. Nigg · 2015 · Oncogene
A Novel Interaction between hScrib and PP1γ Downregulates ERK Signaling and Suppresses Oncogene-Induced Cell Transformation
Kazunori Nagasaka, Takayuki Seiki, Aki Yamashita, Paola Massimi, Vanitha Krishna Subbaiah, Miranda Thomas, Christian Kranjec, Kei Kawana, Shunsuke Nakagawa, Tetsu Yano et al. · 2013 · PLoS ONE
MCC, a new interacting protein for Scrib, is required for cell migration in epithelial cells
Camille Arnaud, Michaël Sebbagh, Sébastien Nola, Stéphane Audebert, Ghislain Bidaut, Aurélie Hermant, Odile Gayet, Nelson Dusetti, Vincent Ollendorff, Marie-Josée Santoni et al. · 2009 · FEBS Letters
Loss of the Polarity Protein PAR3 Activates STAT3 Signaling via an Atypical Protein Kinase C (aPKC)/NF-κB/Interleukin-6 (IL-6) Axis in Mouse Mammary Cells
Richard A. Guyer, Ian G. Macara · 2015 · Journal of Biological Chemistry
Cell Polarity and Migration: Emerging Role for the Endosomal Sorting Machinery
Viola Hélène Lobert, Harald Stenmark · 2011 · Physiology
Noise during mouthbrooding impairs maternal care behaviors and juvenile development and alters brain transcriptomes in the African cichlid fish Astatotilapia burtoni
Julie M. Butler, Karen P. Maruska · 2020 · Genes Brain & Behavior
Scribble1 plays an important role in the pathogenesis of neural tube defects through its mediating effect of Par-3 and Vangl1/2 localization
Kharfallah, Fares, Guyot, Marie Claude, El Hassan, Abdul Rahman, Allache, Redouane, Merello, Elisa, De Marco, Patrizia, Di Cristo, Graziella, Capra, Valeria, Kibar, Zoha · 2017 · Human Molecular Genetics
Phosphorylation state regulates the localization of Scribble at adherens junctions and its association with E-cadherin–catenin complexes
Ken Yoshihara, Junichi Ikenouchi, Yasushi Izumi, Masaya Akashi, Shöichiro Tsukita, Mikio Furuse · 2010 · Experimental Cell Research
Repression of SRF target genes is critical for Myc‐dependent apoptosis of epithelial cells
Katrin E. Wiese, Heidi M. Haikala, Björn von Eyß, Elmar Wolf, Cyril Esnault, Andreas Rosenwald, Richard Treisman, Juha T. Klefström, Martin Eilers · 2015 · The EMBO Journal
Molecular mechanisms of OLIG2 transcription factor in brain cancer
Igor F. Tsigelny, Valentina L. Kouznetsova, Nathan Lian, Santosh Kesari · 2016 · Oncotarget
The polarity protein Scribble positions DLC3 at adherens junctions to regulate Rho signaling
Hendrick, Janina, Franz-Wachtel, Mirita, Moeller, Yvonne, Schmid, Simone, Macek, Boris, Olayioye, Monilola A. · 2016 · Journal of Cell Science
Connexin 43 Loss Triggers Cell Cycle Entry and Invasion in Non-Neoplastic Breast Epithelium: A Role for Noncanonical Wnt Signaling
Sabreen F. Fostok, Mirvat El‐Sibai, Dana Bazzoun, Sophie A. Lelièvre, Rabih Talhouk · 2019 · Cancers
Disruption of epithelial architecture caused by loss of PTEN or by oncogenic mutant p110α/PIK3CA but not by HER2 or mutant AKT1
Fredrik M. Berglund, Nimmi R. Weerasinghe, L Davidson, Jina Lim, Britta Johanna Eickholt, Nicholas R. Leslie · 2012 · Oncogene
Transcriptome dynamics in the asexual cycle of the chordate Botryllus schlosseri
Davide Campagna, Fabio Gasparini, Nicola Franchi, Nicola Vitulo, Francesca Ballin, Lucia Manni, Giorgio Valle, Loriano Ballarin · 2016 · BMC Genomics
Zinc transporter 2 interacts with vacuolar ATPase and is required for polarization, vesicle acidification, and secretion in mammary epithelial cells
Sooyeon Lee, Olivia C. Rivera, Shannon L. Kelleher · 2017 · Journal of Biological Chemistry
WIF1 is a frequent target for epigenetic silencing in squamous cell carcinoma of the cervix
Amber L. Delmas, Bridget M. Riggs, Carolina E. Pardo, Lisa M. Dyer, Russell P. Darst, Eugene G. Izumchenko, Mänette Monroe, Ardeshir Hakam, Michael P. Kladde, Erin M. Siegel et al. · 2011 · Carcinogenesis