Cited by 213

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A Global In Vivo Drosophila RNAi Screen Identifies NOT3 as a Conserved Regulator of Heart Function

Neely, G. Gregory, Kuba, Keiji, Cammarato, Anthony, Isobe, Kazuya, Amann, Sabine, Zhang, Liyong, Murata, Mitsushige, Elmén, Lisa, Gupta, Vaijayanti, Arora, Suchir, Sarangi, Rinku, Dan, Debasis, Fujisawa, Susumu, Usami, Takako, Xia, Cui-ping, Keene, Alex C., Alayari, Nakissa N., Yamakawa, Hiroyuki, Elling, Ulrich, Berger, Christian, Novatchkova, Maria, Koglgruber, Rubina, Fukuda, Keiichi, Nishina, Hiroshi, Isobe, Mitsuaki, Pospisilik, J. Andrew, Imai, Yumiko, Pfeufer, Arne, Hicks, Andrew A., Pramstaller, Peter P., Subramaniam, Sai, Kimura, Akinori, Ocorr, Karen, Bodmer, Rolf, Penninger, Josef M.·2010·Cell

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Crossref · 10.1016/j.cell.2010.02.023

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  • This hit rate is well above the reported hit rate (10%) of a genome-wide cardiac RNAi screen and comparable to the 53% of a targeted approach based on sequence information of CHD patients.

    “This is well above the reported hit rate (10%) of a genome-wide cardiac RNAi screen [43] and is comparable to the 53% of a targeted approach based on sequence information of CHD patients [42].”

    From A cis-regulatory-directed pipeline for the identification of genes involved in cardiac development and disease (2021) · cites this paper as [43]

    The Results report that approximately 10% of 80 randomly selected RNAi lines in a prescreen began to die at increased temperature. The paper did conduct a genome-wide cardiac RNAi screen, but the cited 10% figure describes the prescreen, not a reported hit rate for the genome-wide screen. The 53% figure is attributed to a different citation and is not assessed here. (LLM, conf=0.88)

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Research works printed but not linked: 50

  1. Alayari, 2009, Fluorescent Labeling of Drosophila Heart Structures, J. Vis. Exp., 10.3791/1423-v · DOI
  2. Albert, 2000, Isolation and characterization of human orthologs of yeast CCR4-NOT complex subunits, Nucleic Acids Res., 28, 809, 10.1093/nar/28.3.809 · DOI
  3. Behm-Ansmant, 2006, mRNA degradation by miRNAs and GW182 requires both CCR4:NOT deadenylase and DCP1:DCP2 decapping complexes, Genes Dev., 20, 1885, 10.1101/gad.1424106 · DOI
  4. Bodmer, 1995, Heart development in Drosophila and its relationship to vertebrates, Trends Cardiovasc. Med., 5, 21, 10.1016/1050-1738(94)00032-Q · DOI
  5. Cripps, 2002, Control of cardiac development by an evolutionarily conserved transcriptional network, Dev. Biol., 246, 14, 10.1006/dbio.2002.0666 · DOI
  6. Denis, 1984, Identification of new genes involved in the regulation of yeast alcohol dehydrogenase II, Genetics, 108, 833, 10.1093/genetics/108.4.833 · DOI
  7. Dietzl, 2007, A genome-wide transgenic RNAi library for conditional gene inactivation in Drosophila, Nature, 448, 151, 10.1038/nature05954 · DOI · Paper page
  8. Fink, 2009, A new method for detection and quantification of heartbeat parameters in Drosophila, zebrafish, and embryonic mouse hearts, Biotechniques, 46, 101, 10.2144/000113078 · DOI
  9. Gordon, 1977, Predicting coronary heart disease in middle-aged and older persons. The Framington study, JAMA, 238, 497, 10.1001/jama.1977.03280060041018 · DOI
  10. Han, 2005, Hand is a direct target of Tinman and GATA factors during Drosophila cardiogenesis and hematopoiesis, Development, 132, 3525, 10.1242/dev.01899 · DOI
  11. Hu, 2009, A genome-wide RNAi screen identifies a new transcriptional module required for self-renewal, Genes Dev., 23, 837, 10.1101/gad.1769609 · DOI
  12. Jayne, 2006, Involvement of the SMRT/NCoR-HDAC3 complex in transcriptional repression by the CNOT2 subunit of the human Ccr4-Not complex, Biochem. J., 398, 461, 10.1042/BJ20060406 · DOI
  13. Joza, 2005, Muscle-specific loss of apoptosis-inducing factor leads to mitochondrial dysfunction, skeletal muscle atrophy, and dilated cardiomyopathy, Mol. Cell. Biol., 25, 10261, 10.1128/MCB.25.23.10261-10272.2005 · DOI
  14. Kuba, 2007, Impaired heart contractility in Apelin gene-deficient mice associated with aging and pressure overload, Circ. Res., 101, e32, 10.1161/CIRCRESAHA.107.158659 · DOI
  15. Lakatta, 2003, Arterial and cardiac aging: major shareholders in cardiovascular disease enterprises: Part II: the aging heart in health: links to heart disease, Circulation, 107, 346, 10.1161/01.CIR.0000048893.62841.F7 · DOI
  16. Laribee, 2007, CCR4/NOT complex associates with the proteasome and regulates histone methylation, Proc. Natl. Acad. Sci. USA, 104, 5836, 10.1073/pnas.0607996104 · DOI
  17. Lo, 2001, A role for the COUP-TF-related gene seven-up in the diversification of cardioblast identities in the dorsal vessel of Drosophila, Mech. Dev., 104, 49, 10.1016/S0925-4773(01)00361-6 · DOI
  18. Morita, 2005, Genetic causes of human heart failure, J. Clin. Invest., 115, 518, 10.1172/JCI24351 · DOI
  19. Moss, 2005, Long QT syndrome: from channels to cardiac arrhythmias, J. Clin. Invest., 115, 2018, 10.1172/JCI25537 · DOI
  20. Mudd, 2008, Tackling heart failure in the twenty-first century, Nature, 451, 919, 10.1038/nature06798 · DOI
  21. Newton-Cheh, 2009, Common variants at ten loci influence QT interval duration in the QTGEN Study, Nature genetics, 41, 399, 10.1038/ng.364 · DOI
  22. Ocorr, 2007, Genetic control of heart function and aging in Drosophila, Trends Cardiovasc. Med., 17, 177, 10.1016/j.tcm.2007.04.001 · DOI
  23. Ocorr, 2007, KCNQ potassium channel mutations cause cardiac arrhythmias in Drosophila that mimic the effects of aging, Proc. Natl. Acad. Sci. USA, 104, 3943, 10.1073/pnas.0609278104 · DOI
  24. Paternostro, 2001, Age-associated cardiac dysfunction in Drosophila melanogaster, Circ. Res., 88, 1053, 10.1161/hh1001.090857 · DOI
  25. Peng, 2008, Regulators of cellular levels of histone acetylation in Saccharomyces cerevisiae, Genetics, 179, 277, 10.1534/genetics.107.085068 · DOI
  26. Pfeufer, 2009, Common variants at ten loci modulate the QT interval duration in the QTSCD Study, Nat. Genet., 41, 407, 10.1038/ng.362 · DOI
  27. Qian, 2009, Partial loss of GATA factor Pannier impairs adult heart function in Drosophila, Hum. Mol. Genet., 18, 3153, 10.1093/hmg/ddp254 · DOI
  28. Qian, 2008, Transcription factor neuromancer/TBX20 is required for cardiac function in Drosophila with implications for human heart disease, Proc. Natl. Acad. Sci. USA, 105, 19833, 10.1073/pnas.0808705105 · DOI
  29. Ray, 2005, Mutations in and deletions of the Ca2+ channel-encoding gene cacophony, which affect courtship song in Drosophila, have novel effects on heartbeating, J. Neurogenet., 19, 39, 10.1080/01677060590953066 · DOI
  30. Rusconi, 2007, Drosophila Mrityu encodes a BTB/POZ domain-containing protein and is expressed dynamically during development, Int. J. Dev. Biol., 51, 259, 10.1387/ijdb.062233jr · DOI
  31. Sanguinetti, 2006, hERG potassium channels and cardiac arrhythmia, Nature, 440, 463, 10.1038/nature04710 · DOI
  32. Sanyal, 2006, Conditional mutations in SERCA, the Sarco-endoplasmic reticulum Ca2+-ATPase, alter heart rate and rhythmicity in Drosophila, J. Comp. Physiol. [B], 176, 253, 10.1007/s00360-005-0046-7 · DOI
  33. Tucker, 2001, The transcription factor associated Ccr4 and Caf1 proteins are components of the major cytoplasmic mRNA deadenylase in Saccharomyces cerevisiae, Cell, 104, 377, 10.1016/S0092-8674(01)00225-2 · DOI
  34. Wang, 1996, Positional cloning of a novel potassium channel gene: KVLQT1 mutations cause cardiac arrhythmias, Nat. Genet., 12, 17, 10.1038/ng0196-17 · DOI
  35. Yusuf, 2001, Global burden of cardiovascular diseases: part I: general considerations, the epidemiologic transition, risk factors, and impact of urbanization, Circulation, 104, 2746, 10.1161/hc4601.099487 · DOI
  36. Akasaka, T., Klinedinst, S., Ocorr, K., Bustamante, E.L., Kim, S.K., and Bodmer, R. (2006). The ATP-sensitive potassium (KATP) channel-encoded dSUR gene is required for Drosophila heart function and is regulated by tinman. Proc. Natl. Acad. Sci. USA 103, 11999–12004. · DOI
  37. Alayari, N.N., Vogler, G., Taghli-Lamallem, O., Ocorr, K., Bodmer, R., and Cammarato, A. (2009). Fluorescent Labeling of Drosophila Heart Structures. J. Vis. Exp. 10.3791/1423. · DOI
  38. Cammarato, A., Dambacher, C.M., Knowles, A.F., Kronert, W.A., Bodmer, R., Ocorr, K., and Bernstein, S.I. (2008). Myosin transducer mutations differentially affect motor function, myofibril structure, and the performance of skeletal and cardiac muscles. Mol. Biol. Cell 19, 553–562. · DOI
  39. Cheung, P., Tanner, K.G., Cheung, W.L., Sassone-Corsi, P., Denu, J.M., and Allis, C.D. (2000). Synergistic coupling of histone H3 phosphorylation and acetylation in response to epidermal growth factor stimulation. Mol. Cell 5, 905–915. · DOI
  40. Dietzl, G., Chen, D., Schnorrer, F., Su, K.C., Barinova, Y., Fellner, M., Gasser, B., Kinsey, K., Oppel, S., Scheiblauer, S., et al. (2007). A genome-wide transgenic RNAi library for conditional gene inactivation in Drosophila. Nature 448, 151–156. · DOI · Paper page
  41. Fink, M., Callol-Massot, C., Chu, A., Ruiz-Lozano, P., Izpisua Belmonte, J.C., Giles, W., Bodmer, R., and Ocorr, K. (2009). A new method for detection and quantification of heartbeat parameters in Drosophila, zebrafish, and embryonic mouse hearts. Biotechniques 46, 101–113. · DOI
  42. Han, Z., and Olson, E.N. (2005). Hand is a direct target of Tinman and GATA factors during Drosophila cardiogenesis and hematopoiesis. Development 132, 3525–3536. · DOI
  43. Kuba, K., Zhang, L., Imai, Y., Arab, S., Chen, M., Maekawa, Y., Leschnik, M., Leibbrandt, A., Markovic, M., Makovic, M., et al. (2007). Impaired heart contractility in Apelin gene-deficient mice associated with aging and pressure overload. Circ. Res. 101, e32–e42. · DOI
  44. Kuzniar, A., van Ham, R.C., Pongor, S., and Leunissen, J.A. (2008). The quest for orthologs: finding the corresponding gene across genomes. Trends Genet. 24, 539–551. · DOI
  45. Lo, P.C., and Frasch, M. (2001). A role for the COUP-TF-related gene seven-up in the diversification of cardioblast identities in the dorsal vessel of Drosophila. Mech. Dev. 104, 49–60. · DOI
  46. Murakami, M., Ohba, T., Wu, T.W., Fujisawa, S., Suzuki, T., Takahashi, Y., Takahashi, E., Watanabe, H., Miyoshi, I., Ono, K., et al. (2007). Modified sympathetic regulation in N-type calcium channel null-mouse. Biochem. Biophys. Res. Commun. 354, 1016–1020. · DOI
  47. Ocorr, K., Reeves, N.L., Wessells, R.J., Fink, M., Chen, H.S., Akasaka, T., Yasuda, S., Metzger, J.M., Giles, W., Posakony, J.W., and Bodmer, R. (2007). KCNQ potassium channel mutations cause cardiac arrhythmias in Drosophila that mimic the effects of aging. Proc. Natl. Acad. Sci. USA 104, 3943–3948. · DOI
  48. Paternostro, G., Vignola, C., Bartsch, D.U., Omens, J.H., McCulloch, A.D., and Reed, J.C. (2001). Age-associated cardiac dysfunction in Drosophila melanogaster. Circ. Res. 88, 1053–1058. · DOI
  49. Pfeufer, A., Sanna, S., Arking, D.E., Müller, M., Gateva, V., Fuchsberger, C., Ehret, G.B., Orrú, M., Pattaro, C., Köttgen, A., et al. (2009). Common variants at ten loci modulate the QT interval duration in the QTSCD Study. Nat. Genet. 41, 407–414. · DOI
  50. Wolf, M.J., Amrein, H., Izatt, J.A., Choma, M.A., Reedy, M.C., and Rockman, H.A. (2006). Drosophila as a model for the identification of genes causing adult human heart disease. Proc. Natl. Acad. Sci. USA 103, 1394–1399. · DOI

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Metadata

Authors
Neely, G. G., Kuba, K., Cammarato, A., Isobe, K., Amann, S., Zhang, L., Murata, M., Elmén, L., Gupta, V., Arora, S., Sarangi, R., Dan, D., Fujisawa, S., Usami, T., Xia, C.-P., Keene, A. C., Alayari, N. N., Yamakawa, H., Elling, U., Berger, C., Novatchkova, M., Koglgruber, R., Fukuda, K., Nishina, H., Isobe, M., Pospisilik, J. A., Imai, Y., Pfeufer, A., Hicks, A. A., Pramstaller, P. P., Subramaniam, S., Kimura, A., Ocorr, K., Bodmer, R., & Penninger, J. M.
Venue
Cell
Publisher
Elsevier BV
Published
2010-04
Volume
141
Issue
1
Pages
142-153
ISSN
0092-8674
Cited by
213
References
4
Language
en

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