Cardiovascular Disease

Major outcomes in high-risk hypertensive patients randomized to angiotensin-converting enzyme inhibitor or calcium channel blocker vs diuretic: the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT)

The ALLHAT Officers and Coordinators for the ALLHAT Collaborative Research Group (2002) · JAMA: The Journal of the American Medical Association · doi:10.1001/jama.288.23.2981 · Cited by 5,664 · see citing works

A mechanistic link between an inherited and an acquird cardiac arrthytmia: HERG encodes the IKr potassium channel

Sanguinetti, M. C., Jiang, C., Curran, M. E., & Keating, M. T. (1995) · Cell · doi:10.1016/0092-8674(95)90340-2 · Cited by 2,422 · see citing works

Prevalence of Hypertrophic Cardiomyopathy in a General Population of Young Adults

Maron, B. J., Gardin, J. M., Flack, J. M., Gidding, S. S., Kurosaki, T., & Bild, D. E. (1995) · Circulation · doi:10.1161/01.cir.92.4.785 · Cited by 2,274 · see citing works

Genetic basis and molecular mechanism for idiopathic ventricular fibrillation

Chen, Q., Kirsch, G. E., Zhang, D., Brugada, R., Brugada, J., Brugada, P., Potenza, D. R., Moya‐Mitjans, À., Borggrefe, M., BREITHARDT, G. E., et al. (1998) · Nature · doi:10.1038/32675 · Cited by 1,823 · see citing works

Pharmacogenomics — Drug Disposition, Drug Targets, and Side Effects

Evans, W. E., & McLeod, H. L. (2003) · New England Journal of Medicine · doi:10.1056/nejmra020526 · Cited by 1,773 · see citing works

Coassembly of KVLQT1 and minK (IsK) proteins to form cardiac IKS potassium channel

Sanguinetti, M. C., Curran, M. E., Zou, A., Shen, J., Specter, P. S., Atkinson, D. L., & Keating, M. T. (1996) · Nature · doi:10.1038/384080a0 · Cited by 1,765 · see citing works

Molecular Mechanisms of Human Hypertension

Lifton, R. P., Gharavi, A. G., & Geller, D. S. (2001) · Cell · doi:10.1016/s0092-8674(01)00241-0 · Cited by 1,686 · see citing works

SCN5A mutations associated with an inherited cardiac arrhythmia, long QT syndrome

Wang, Q. K., Shen, J., Splawski, I., Atkinson, D. L., Li, Z., Robinson, J. L., Moss, A. J., Towbin, J. A., & Keating, M. T. (1995) · Cell · doi:10.1016/0092-8674(95)90359-3 · Cited by 1,682 · see citing works

Accumulation of Dietary Cholesterol in Sitosterolemia Caused by Mutations in Adjacent ABC Transporters

Berge, K. E., Tian, H., Graf, G. A., Yu, L., Grishin, N. V., Schultz, J. R., Kwiterovich, P. O., Shan, B., Barnes, R., & Hobbs, H. H. (2000) · Science · doi:10.1126/science.290.5497.1771 · Cited by 1,645 · see citing works

KvLQT1 and IsK (minK) proteins associate to form the IKS cardiac potassium current

Barhanin, J., Lesage, F., Guillemare, E., Fink, M., Lazdunski, M., & Romey, G. (1996) · Nature · doi:10.1038/384078a0 · Cited by 1,614 · see citing works

Characterization of single-nucleotide polymorphisms in coding regions of human genes

Cargill, M., Altshuler, D., Ireland, J., Sklar, P., Ardlie, K., Patil, N., Lane, C. R., Lim, E. P., Kalyanaraman, N., Nemesh, J., et al. (1999) · Nature Genetics · doi:10.1038/10290 · Cited by 1,547 · see citing works

Human Hypertension Caused by Mutations in WNK Kinases

Wilson, F. H., Disse-Nicodème, S., Choate, K. A., Ishikawa, K., Nelson-Williams, C. J., Desitter, I., Günel, M., Milford, D. V., Lipkin, G. W., Achard, J., et al. (2001) · Science · doi:10.1126/science.1062844 · Cited by 1,466 · see citing works

A molecular basis for familial hypertrophic cardiomyopathy: A β cardiac myosin heavy chain gene missense mutation

Geisterfer-Lowrance, A. A. T., Kass, S., Tanigawa, G., Vosberg, H.-P., McKenna, W., Seidman, C. E., & Seidman, J. G. (1990) · Cell · doi:10.1016/0092-8674(90)90274-i · Cited by 1,380 · see citing works

MiRP1 Forms IKr Potassium Channels with HERG and Is Associated with Cardiac Arrhythmia

Abbott, G. W., Sesti, F., Splawski, I., Buck, M. E., Lehmann, M. H., Timothy, K. W., Keating, M. T., & Goldstein, S. A. N. (1999) · Cell · doi:10.1016/s0092-8674(00)80728-x · Cited by 1,353 · see citing works

Liddle's syndrome: Heritable human hypertension caused by mutations in the β subunit of the epithelial sodium channel

Shimkets, R. A., Warnock, D. G., Bositis, C. M., Nelson-Williams, C. J., Hansson, J. H., Schambelan, M., Gill, J. R., Ulick, S., Milora, R. V., Findling, J. W., et al. (1994) · Cell · doi:10.1016/0092-8674(94)90250-x · Cited by 1,256 · see citing works

Venous thrombosis due to poor anticoagulant response to activated protein C: Leiden Thrombophilia Study

Koster, T., Vandenbroucke, J. P., Rosendaal, F. R., de Ronde, H., Briët, E., & Bertina, R. M. (1993) · The Lancet · doi:10.1016/s0140-6736(05)80081-9 · Cited by 1,236 · see citing works

Spectrum of Mutations in Long-QT Syndrome Genes

Splawski, I., Shen, J., Timothy, K. W., Lehmann, M. H., Priori, S. G., Robinson, J. L., Moss, A. J., Schwartz, P. J., Towbin, J. A., Vincent, G. M., et al. (2000) · Circulation · doi:10.1161/01.cir.102.10.1178 · Cited by 1,231 · see citing works

Gitelman's variant of Barter's syndrome, inherited hypokalaemic alkalosis, is caused by mutations in the thiazide-sensitive Na–Cl cotransporter

Simon, D. B., Nelson-Williams, C. J., BIA, M. J., Ellison, D. H., Karet, F. E., Molina, A. M., Vaara, I., Iwata, F., Cushner, H. M., Koolen, M. I., et al. (1996) · Nature Genetics · doi:10.1038/ng0196-24 · Cited by 1,206 · see citing works

A chimaeric llβ-hydroxylase/aldosterone synthase gene causes glucocorticoid-remediable aldosteronism and human hypertension

Lifton, R. P., Dluhy, R. G., Powers, M., Rich, G. M., Cook, S., Ulick, S., & Lalouel, J.-M. (1992) · Nature · doi:10.1038/355262a0 · Cited by 1,158 · see citing works

Resistance to Activated Protein C as a Basis for Venous Thrombosis

Svensson, P. J., & Dahlbäck, B. (1994) · New England Journal of Medicine · doi:10.1056/nejm199402243300801 · Cited by 1,127 · see citing works

The Genetic Basis for Cardiomyopathy

Seidman, J. G., & Seidman, C. E. (2001) · Cell · doi:10.1016/s0092-8674(01)00242-2 · Cited by 1,043 · see citing works

Inheritance and Drug Response

Weinshilboum, R. M. (2003) · New England Journal of Medicine · doi:10.1056/nejmra020021 · Cited by 1,032 · see citing works

Mutation in the Gene Coding for Coagulation Factor V and the Risk of Myocardial Infarction, Stroke, and Venous Thrombosis in Apparently Healthy Men

Ridker, P. M., Hennekens, C. H., Lindpaintner, K., Stampfer, M. J., Eisenberg, P. R., & Miletich, J. P. (1995) · New England Journal of Medicine · doi:10.1056/nejm199504063321403 · Cited by 1,031 · see citing works

Molecular and Cellular Mechanisms of Cardiac Arrhythmias

Keating, M. T., & Sanguinetti, M. C. (2001) · Cell · doi:10.1016/s0092-8674(01)00243-4 · Cited by 1,003 · see citing works

High risk of thrombosis in patients homozygous for factor V Leiden (activated protein C resistance) [see comments]

Rosendaal, F. R., Koster, T., Vandenbroucke, J. P., & Reitsma, P. H. (1995) · Blood · doi:10.1182/blood.v85.6.1504.bloodjournal8561504 · Cited by 999 · see citing works

Complex promoter and coding region β 2 -adrenergic receptor haplotypes alter receptor expression and predict in vivo responsiveness

Drysdale, C. M., McGraw, D. W., Stack, C. B., Stephens, J. C., Judson, R., Nandabalan, K., Arnold, K., Ruaño, G., & Liggett, S. B. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.97.19.10483 · Cited by 964 · see citing works

Molecular mechanism for an inherited cardiac arrhythmia

Bennett, P. B., Yazawa, K., Makita, N., & George, A. L. (1995) · Nature · doi:10.1038/376683a0 · Cited by 959 · see citing works

The proliferation gene expression signature is a quantitative integrator of oncogenic events that predicts survival in mantle cell lymphoma

Rosenwald, A., Wright, G. W., Wiestner, A. U., Chan, W. C., Connors, J. M., Campo, E., Gascoyne, R. D., Grogan, T. M., Müller-Hermelink, H. K., Smeland, E. B., et al. (2003) · Cancer Cell · doi:10.1016/s1535-6108(03)00028-x · Cited by 905 · see citing works

Bartter's syndrome, hypokalaemic alkalosis with hypercalciuria, is caused by mutations in the Na–K–2CI cotransporter NKCC2

Simon, D. B., Karet, F. E., Hamdan, J. M., Pietro, A. D., Sanjad, S. A., & Lifton, R. P. (1996) · Nature Genetics · doi:10.1038/ng0696-183 · Cited by 898 · see citing works

Finding genes that underlie complex traits.

Glazier, A. M., Nadeau, J. H., & Aitman, T. J. (2002) · Science · doi:10.1126/science.1076641 · Cited by 855 · see citing works

Trends and Disparities in Coronary Heart Disease, Stroke, and Other Cardiovascular Diseases in the United States

Cooper, R., Cutler, J. A., Desvigne-Nickens, P. M., Fortmann, S. P., Friedman, L., Havlik, R. J., Hogelin, G. C., Marler, J. M., McGovern, P. C., Morosco, G. J., et al. (2000) · Circulation · doi:10.1161/01.cir.102.25.3137 · Cited by 830 · see citing works

Mutations in the Gene for Cardiac Myosin-Binding Protein C and Late-Onset Familial Hypertrophic Cardiomyopathy

Niimura, H., Bachinski, L. L., Sangwatanaroj, S., Watkins, H. C., Chudley, A. E., McKenna, W. J., Kristinsson, A., Roberts, R., Sole, M. J., Maron, B. J., et al. (1998) · New England Journal of Medicine · doi:10.1056/nejm199804303381802 · Cited by 757 · see citing works

Mutations in Sarcomere Protein Genes as a Cause of Dilated Cardiomyopathy

Kamisago, M., Sharma, S. D., DePalma, S. R., Solomon, S., Sharma, P., McDonough, B., Smoot, L., Mullen, M. P., Woolf, P. K., Wigle, E. D., et al. (2000) · New England Journal of Medicine · doi:10.1056/nejm200012073432304 · Cited by 720 · see citing works

Prediction of the Risk of Myocardial Infarction from Polymorphisms in Candidate Genes

Yamada, Y., Izawa, H., Ichihara, S., Takatsu, F., Ishihara, H., Hirayama, H., Sone, T., Tanaka, M., & Yokota, M. (2002) · New England Journal of Medicine · doi:10.1056/nejmoa021445 · Cited by 639 · see citing works

Cardiac conduction defects associate with mutations in SCN5A

Schott, J., Alshinawi, C., Kyndt, F., Probst, V., Hoorntje, T. M., Hulsbeek, M. M. F., Wilde, A. A. M., Escande, D., Mannens, M. M. A. M., & Marec, H. L. (1999) · Nature Genetics · doi:10.1038/12618 · Cited by 634 · see citing works

Primary structure and functional expression of the human cardiac tetrodotoxin-insensitive voltage-dependent sodium channel.

Gellens, M., George, A. L., Chen, L. Q., Chahine, M., HORN, R. C. V., Barchi, R. L., & Kallen, R. G. (1992) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.89.2.554 · Cited by 628 · see citing works

Autosomal Recessive Hypercholesterolemia Caused by Mutations in a Putative LDL Receptor Adaptor Protein

Garcia, C. K., Wilund, K., Arca, M., Zuliani, G., Fellin, R., Maioli, M., Calandra, S., Bertolini, S., Cossu, F., Grishin, N., et al. (2001) · Science · doi:10.1126/science.1060458 · Cited by 624 · see citing works

The Role of a Common Variant of the Cholesteryl Ester Transfer Protein Gene in the Progression of Coronary Atherosclerosis

Kuivenhoven, J. A., Jukema, J. W., Zwinderman, A. H., de Knijff, P., McPherson, R., Bruschke, A. V. G., Lie, K. I., & Kastelein, J. J. P. (1998) · New England Journal of Medicine · doi:10.1056/nejm199801083380203 · Cited by 623 · see citing works

Functional polymorphisms of the human multidrug-resistance gene: Multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo

Hoffmeyer, S. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.050585397 · Cited by 599 · see citing works

Mutations in the cardiac troponin I gene associated with hypertrophic cardiomyopathy

Kimura, A., Harada, H., Park, J.-E., Nishi, H., Satoh, M., Takahashi, M., Hiroi, S., Sasaoka, T., Ohbuchi, N., Nakamura, T., et al. (1997) · Nature Genetics · doi:10.1038/ng0897-379 · Cited by 576 · see citing works

Synergistic Polymorphisms of β1- and α2C-Adrenergic Receptors and the Risk of Congestive Heart Failure

Small, K. M., Wagoner, L. E., Levin, A. M., Kardia, S. L. R., & Liggett, S. B. (2002) · New England Journal of Medicine · doi:10.1056/nejmoa020803 · Cited by 524 · see citing works

Variant of SCN5A Sodium Channel Implicated in Risk of Cardiac Arrhythmia

Splawski, I., Timothy, K. W., Tateyama, M., Clancy, C. E., Malhotra, A., Beggs, A. H., Cappuccio, F. P., Sagnella, G. A., Kass, R. S., & Keating, M. T. (2002) · Science · doi:10.1126/science.1073569 · Cited by 523 · see citing works

A common polymorphism associated with antibiotic-induced cardiac arrhythmia

Sesti, F., Abbott, G. W., Wei, J., Murray, K. T., Saksena, S. V., Schwartz, P. J., Priori, S. G., Roden, D. M., George, A. L., & Goldstein, S. A. N. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.180223197 · Cited by 479 · see citing works

BeadArray ™ Technology: Enabling an Accurate, Cost-Effective Approach to High-Throughput Genotyping

Oliphant, A., Barker, D. L. A., Stuelpnagel, J., & Chee, M. S. (2002) · BioTechniques · doi:10.2144/jun0207 · Cited by 462 · see citing works

Activated protein C resistance as an additional risk factor for thrombosis in protein C-deficient families

Koeleman, B. P. C., Reitsma, P. H., Allaart, C. F., & Bertina, R. M. (1994) · Blood · doi:10.1182/blood.v84.4.1031.1031 · Cited by 442 · see citing works

Anticoagulant protein C pathway defective in majority of thrombophilic patients [see comments]

Griffin, J. H., Evatt, B. L., Wideman, C. S., & Fernandez, J. (1993) · Blood · doi:10.1182/blood.v82.7.1989.1989 · Cited by 415 · see citing works

A sodium-channel mutation causes isolated cardiac conduction disease

Tan, H. L., Bink‐Boelkens, M. T. E., Bezzina, C. R., Viswanathan, P. C., Beaufort‐Krol, G. C. M., van Tintelen, J. P., van den Berg, M. P., Wilde, A. A. M., & Balser, J. R. (2001) · Nature · doi:10.1038/35059090 · Cited by 398 · see citing works

A de novo missense mutation of the beta subunit of the epithelial sodium channel causes hypertension and Liddle syndrome, identifying a proline-rich segment critical for regulation of channel activity.

Hansson, J. H., Schild, L., Lu, Y., Wilson, T. A., Gautschi, I., Shimkets, R. A., Nelson-Williams, C. J., Rossier, B. C., & Lifton, R. P. (1995) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.92.25.11495 · Cited by 367 · see citing works

The Effect of Common Polymorphisms of the β2-Adrenergic Receptor on Agonist-Mediated Vascular Desensitization

Dishy, V., Sofowora, G. G., Xie, H., Kim, R. B., Byrne, D. W., Stein, C. M., & Wood, A. J. J. (2001) · New England Journal of Medicine · doi:10.1056/nejmoa010819 · Cited by 363 · see citing works

Hereditary hypertension caused by chimaeric gene duplications and ectopic expression of aldosterone synthase

Lifton, R. P., Dluhy, R. G., Powers, M., Rich, G. M., Gutkin, M. C., Fallo, F., Gill, J. R., Feld, L. G., Ganguly, A., Laidlaw, J. C., et al. (1992) · Nature Genetics · doi:10.1038/ng0992-66 · Cited by 329 · see citing works

MDR1 Genotype-Related Pharmacokinetics of Digoxin After Single Oral Administration in Healthy Japanese Subjects

Sakaeda, T., Nakamura, T., Horinouchi, M., Kakumoto, M., Ohmoto, N., Sakai, T., Morita, Y., Tamura, T., Aoyama, N., Hirai, M., et al. (2001) · Pharmaceutical Research · doi:10.1023/a:1012244520615 · Cited by 322 · see citing works

Role of the deletion of polymorphism of the angiotensin converting enzyme gene in the progression and therapeutic responsiveness of IgA nephropathy.

Yoshida, H., Mitarai, T., Kawamura, T., KITAJIMA, T., Miyazaki, Y., Nagasawa, R., Kawaguchi, Y., Kubo, H., Ichikawa, I., & Sakai, O. (1995) · Journal of Clinical Investigation · doi:10.1172/jci118270 · Cited by 318 · see citing works

Resistance to activated protein C as an additional genetic risk factor in hereditary deficiency of protein S

Zöller, B., Berntsdotter, A., de Frutos, P. G., & Dahlbäck, B. (1995) · Blood · doi:10.1182/blood.v85.12.3518.bloodjournal85123518 · Cited by 302 · see citing works

Single Nucleotide Polymorphisms in Multiple Novel Thrombospondin Genes May Be Associated With Familial Premature Myocardial Infarction

Topol, E. J., McCarthy, J. J., Gabriel, S., Moliterno, D. J., Rogers, W. J., Newby, L. K., Freedman, M., Metivier, J., Cannata, R., O’Donnell, C. J., et al. (2001) · Circulation · doi:10.1161/hc4701.100910 · Cited by 282 · see citing works

The Cholesterol Quartet

Goldstein, J. L., & Brown, M. S. (2001) · Science · doi:10.1126/science.1061815 · Cited by 242 · see citing works

The Apolipoprotein ε4 Allele Determines Prognosis and the Effect on Prognosis of Simvastatin in Survivors of Myocardial Infarction

Gerdes, L. U., Gerdes, C., Kervinen, K., Savolainen, M. J., Klausen, I. C., HANSEN, P. S., Kesäniemi, Y. A., & Færgeman, O. (2000) · Circulation · doi:10.1161/01.cir.101.12.1366 · Cited by 235 · see citing works

Factor V Leiden (FV R506Q) in Families with Inherited Antithrombin Deficiency

van Boven, H. H., Reitsma, P. H., Rosendaal, F. R., Bayston, T. A., Chowdhury, V., Borg, J. Y., Bauer, K. A., Scharrer, I., Conard, J., & Lane, D. A. (1996) · Thrombosis and Haemostasis · doi:10.1055/s-0038-1650289 · Cited by 227 · see citing works

Genotype-phenotype correlations in hypertrophic cardiomyopathy. Insights provided by comparisons of kindreds with distinct and identical beta-myosin heavy chain gene mutations.

Fananapazir, L., & Epstein, N. D. (1994) · Circulation · doi:10.1161/01.cir.89.1.22 · Cited by 226 · see citing works

Angiotensin-I Converting Enzyme Genotypes and Left Ventricular Hypertrophy in Patients With Hypertrophic Cardiomyopathy

Lechin, M. E., Quiñones, M. A., Omran, A., Hill, R., Yu, Q., Rakowski, H., Wigle, D., Liew, C. C., Sole, M. J., Roberts, R., et al. (1995) · Circulation · doi:10.1161/01.cir.92.7.1808 · Cited by 210 · see citing works

Pharmacogenetic Interactions Between β-Blocker Therapy and the Angiotensin-Converting Enzyme Deletion Polymorphism in Patients With Congestive Heart Failure

McNamara, D. M., Holubkov, R., Janosko, K. M., Palmer, A., Wang, J. J., MacGowan, G. A., Murali, S., Rosenblum, W. D., London, B., & Feldman, A. M. (2001) · Circulation · doi:10.1161/01.cir.103.12.1644 · Cited by 192 · see citing works

Apolipoprotein E genotype affects plasma lipid response to atorvastatin in a gender specific manner

Pedro‐Botet, J., Schaefer, E. J., Bakker-Arkema, R. G., Black, D. M., Stein, E., Corella, D., & Ordovás, J. M. (2001) · Atherosclerosis · doi:10.1016/s0021-9150(01)00410-5 · Cited by 173 · see citing works

β 2 -Adrenoceptor Polymorphism Determines Vascular Reactivity in Humans

Cockcroft, J. R., Gazis, A., Cross, D. J., Wheatley, A. P., Dewar, J. C., Hall, I. P., & Noon, J. P. (2000) · Hypertension · doi:10.1161/01.hyp.36.3.371 · Cited by 160 · see citing works

Effect of angiotensin-converting enzyme (ACE) gene polymorphism on progression of renal disease and the influence of ACE inhibition in IDDM patients: findings from the EUCLID Randomized Controlled Trial. EURODIAB Controlled Trial of Lisinopril in IDDM.

Penno, G., Chaturvedi, N., Talmud, P. J., Cotroneo, P., Manto, A., Nannipieri, M., Luong, L. A., & Fuller, J. (1998) · Diabetes · doi:10.2337/diabetes.47.9.1507 · Cited by 160 · see citing works

Homozygous Mutation in Cardiac Troponin T

Ho, C. Y., Lever, H. M., DeSanctis, R. W., Farver, C. F., Seidman, J. G., & Seidman, C. E. (2000) · Circulation · doi:10.1161/01.cir.102.16.1950 · Cited by 150 · see citing works

Insertion-Deletion Polymorphism of the ACE Gene Modulates Reversibility of Endothelial Dysfunction With ACE Inhibition

Prasad, A., Narayanan, S. N., Husain, S., Padder, F. A., Waclawiw, M. A., Epstein, N., & Quyyumi, A. A. (2000) · Circulation · doi:10.1161/01.cir.102.1.35 · Cited by 133 · see citing works

β2-Adrenergic Receptor Pharmacogenetics

Liggett, S. B. (2000) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.161.supplement_2.a1q4-10 · Cited by 130 · see citing works

Identification of genes differentially expressed in breast cancer cells treated with tamoxifen, using microarray-based expression profiling

Lee, A., Krishnasamy, A., Epstein, R. J., & Hong, G. S. (2001) · Nature Genetics · doi:10.1038/87170 · Cited by 126 · see citing works

Gene Expression Profiling of Human Stent-Induced Neointima by cDNA Array Analysis of Microscopic Specimens Retrieved by Helix Cutter Atherectomy

Zohlnhöfer, D., Klein, C. A., Richter, T., Brandl, R., Murr, A., Nührenberg, T. G., Schömig, A., Baeuerle, P. A., & Neumann, F. (2001) · Circulation · doi:10.1161/01.cir.103.10.1396 · Cited by 125 · see citing works

Left Ventricular Hypertrophy With Exercise and ACE Gene Insertion/Deletion Polymorphism

Myerson, S. G., Montgomery, H., Whittingham, M., Jubb, M., WORLD, M. J., Humphries, S. E., & Pennell, D. J. (2001) · Circulation · doi:10.1161/01.cir.103.2.226 · Cited by 124 · see citing works

AT 1 Receptor A/C 1166 Polymorphism Contributes to Cardiac Hypertrophy in Subjects With Hypertrophic Cardiomyopathy

Osterop, A. P. R. M., Kofflard, M. J. M., Sandkuijl, L. A., ten Cate, F. J., Krams, R., Schalekamp, M. A. D. H., & Danser, A. H. J. (1998) · Hypertension · doi:10.1161/01.hyp.32.5.825 · Cited by 122 · see citing works

Variability of Thrombosis among Homozygous Siblings with Resistance to Activated Protein C Due to an Arg-to-Gln Mutation in the Gene for Factor V

Greengard, J. S., Eichinger, S., Griffin, J. H., & Bauer, K. A. (1994) · New England Journal of Medicine · doi:10.1056/nejm199412083312305 · Cited by 119 · see citing works

The Influence of the Angiotensin I Converting Enzyme Genotype in Familial Hypertrophic Cardiomyopathy Varies with the Disease Gene Mutation

Tesson, F., Dufour, C., Moolman, J. C., Carrier, L., Al‐Mahdawi, S., Chojnowska, L., Dubourg, O., Soubrier, F., Brink, P. A., Michel Komajda, N., et al. (1997) · Journal of Molecular and Cellular Cardiology · doi:10.1006/jmcc.1996.0332 · Cited by 118 · see citing works

Genetic polymorphisms in the renin-angiotensin-aldosterone system associated with expression of left ventricular hypertrophy in hypertrophic cardiomyopathy: a study of five polymorphic genes in a family with a disease causing mutation in the myosin binding protein C gene

Ortlepp, J. R., Vosberg, H. P., Reith, S., Ohme, F., Mahon, N. G., Schröder, D., Klues, H. G., Hanrath, P., & McKenna, W. J. (2002) · Heart · doi:10.1136/heart.87.3.270 · Cited by 111 · see citing works

High-throughput screening for evidence of association by using mass spectrometry genotyping on DNA pools

Mohlke, K. L., Erdos, M. R., Scott, L. J., Fingerlin, T. E., Jackson, A., Silander, K., Hollstein, P. E., Boehnke, M., & Collins, F. S. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.262661399 · Cited by 105 · see citing works

Impact of Laboratory Molecular Diagnosis on Contemporary Diagnostic Criteria for Genetically Transmitted Cardiovascular Diseases: Hypertrophic Cardiomyopathy, Long-QT Syndrome, and Marfan Syndrome

Maron, B. J., Moller, J. H., Seidman, C. E., Vincent, G. M., Dietz, H. C., Moss, A. J., Towbin, J. A., Sondheimer, H. M., Pyeritz, R. E., McGee, G., et al. (1998) · Circulation · doi:10.1161/01.cir.98.14.1460 · Cited by 103 · see citing works

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