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Microphthalmia-Associated Transcription Factor Is a Critical Transcriptional Regulator of Melanoma Inhibitor of Apoptosis in Melanomas

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The Hermansky-Pudlak Syndrome 1 (HPS1) and HPS4 Proteins Are Components of Two Complexes, BLOC-3 and BLOC-4, Involved in the Biogenesis of Lysosome-related Organelles

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Rab17 Localizes to Recycling Endosomes and Regulates Receptor-mediated Transcytosis in Epithelial Cells

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Trypsin IV or Mesotrypsin and p23 Cleave Protease-activated Receptors 1 and 2 to Induce Inflammation and Hyperalgesia

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A genomic screen identifies TYRO3 as a MITF regulator in melanoma

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Rab7 and Rab27a control two motor protein activities involved in melanosomal transport

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Junctional Adhesion Molecules (JAM)-B and -C Contribute to Leukocyte Extravasation to the Skin and Mediate Cutaneous Inflammation

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Glutathione transferase omega 1-1 (GSTO1-1) plays an anti-apoptotic role in cell resistance to cisplatin toxicity

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MC1R Variants Increase Risk of Melanomas Harboring BRAF Mutations

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GREB1 is a novel androgen‐regulated gene required for prostate cancer growth

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Plexin C1, A Receptor for Semaphorin 7A, Inactivates Cofilin and Is a Potential Tumor Suppressor for Melanoma Progression

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Revised Nomenclature for Mammalian Vacuolar-Type H+-ATPase Subunit Genes

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Confirmation of a BRAF mutation‐associated gene expression signature in melanoma

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Stress-induced regulation of eukaryotic elongation factor 2 kinase by SB 203580-sensitive and −insensitive pathways

Knebel, A., Haydon, C. E., MORRICE, N. A., & Cohen, P. (2002) · Biochemical Journal · doi:10.1042/bj20020916 · Cited by 80

Analysis of a Truncated Form of Cathepsin H in Human Prostate Tumor Cells

Waghray, A., Keppler, D., Sloane, B. F., Schuger, L. A., & Chen, Y. Q. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m109557200 · Cited by 74

The Microphthalmia Transcription Factor (Mitf) Controls Expression of the Ocular Albinism Type 1 Gene: Link between Melanin Synthesis and Melanosome Biogenesis

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Bmx tyrosine kinase regulates TLR4-induced IL-6 production in human macrophages independently of p38 MAPK and NFκB activity

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Novel Role for RGS1 in Melanoma Progression

Rangel, J., Nosrati, M., Leong, S. P. L., Haqq, C., Miller, J. R., Sagebiel, R. W., & Kashani–Sabet, M. (2008) · The American Journal of Surgical Pathology · doi:10.1097/pas.0b013e31816fd53c · Cited by 72

Identification of Survival Genes in Human Glioblastoma Cells by Small Interfering RNA Screening

Thaker, N. G., Zhang, F., McDonald, P. R., Shun, T. Y., Lewen, M. D., Pollack, I. F., & Lazo, J. S. (2009) · Molecular Pharmacology · doi:10.1124/mol.109.058024 · Cited by 72

The GTPase Rab3b/3c-positive recycling vesicles are involved in cross-presentation in dendritic cells

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The MICAL proteins and rab1: a possible link to the cytoskeleton?

Fischer, J., Weide, T., & Barnekow, A. (2005) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2004.12.182 · Cited by 67

CK2 phosphorylation of eukaryotic translation initiation factor 5 potentiates cell cycle progression

Homma, M. K., Wada, I., Suzuki, T., Yamaki, J., Krebs, E. G., & Homma, Y. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0506791102 · Cited by 64

Comparative evolutionary analysis of VPS33 homologues: genetic and functional insights

Gissen, P., Johnson, C. A., Gentle, D., Hurst, L. D., Doherty, A. J., O’Kane, C. J., Kelly, D. A., & Maher, E. R. (2005) · Human Molecular Genetics · doi:10.1093/hmg/ddi137 · Cited by 61

Cyclin B2 suppresses mitotic failure and DNA re-replication in human somatic cells knocked down for both cyclins B1 and B2

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DIXDC1 targets p21 and cyclin D1 via PI3K pathway activation to promote colon cancer cell proliferation

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Munc18-Syntaxin Complexes and Exocytosis in Human Platelets

Houng, A. K., Polgár, J., & Reed, G. L. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m212465200 · Cited by 52

Functioning methionine sulfoxide reductases A and B are present in human epidermal melanocytes in the cytosol and in the nucleus

Schallreuter, K. U., Rübsam, K., Chavan, B., Zothner, C., Gillbro, J. M., Spencer, J. D., & Wood, J. M. (2006) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2006.01.124 · Cited by 52

Simplet controls cell proliferation and gene transcription during zebrafish caudal fin regeneration

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JISTIC: Identification of Significant Targets in Cancer

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γ‐BAR, a novel AP‐1‐interacting protein involved in post‐Golgi trafficking

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GTP-dependent Secretion from Neutrophils Is Regulated by Cdk5

Rosales, J. L., Ernst, J., Hallows, J. L., & Lee, K. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m408467200 · Cited by 45

Targeting β2-Microglobulin Mediated Signaling as a Novel Therapeutic Approach for Human Renal Cell Carcinoma

Nomura, T., Huang, W., Seo, S., Zhau, H. E., Mimata, H., & Chung, L. W. K. (2007) · The Journal of Urology · doi:10.1016/j.juro.2007.03.007 · Cited by 44

RING-dependent tumor suppression and G2/M arrest induced by the TRC8 hereditary kidney cancer gene

Brauweiler, A. M., Lorick, K. L., Lee, J. P., Tsai, Y. C., Chan, D., Weissman, A. M., Drabkin, H. A., & Gemmill, R. M. (2006) · Oncogene · doi:10.1038/sj.onc.1210017 · Cited by 41

The Human Stress-Activated Protein kin17 Belongs to the Multiprotein DNA Replication Complex and Associates In Vivo with Mammalian Replication Origins

Miccoli, L., Frouin, I., Novac, O., Paola, D. D., Harper, F., Zannis‐Hadjopoulos, M., Maga, G., Biard, D. S. F., & Angulo, J. F. (2005) · Molecular and Cellular Biology · doi:10.1128/mcb.25.9.3814-3830.2005 · Cited by 35

Protein phosphatase 1H, overexpressed in colon adenocarcinoma, is associated with CSE1L

Sugiura, T., Noguchi, Y., Sakurai, K., & Hattori, C. (2008) · Cancer Biology & Therapy · doi:10.4161/cbt.7.2.5302 · Cited by 30

Characterisation of the human APC1 , the largest subunit of the anaphase-promoting complex

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Epithelial-specific transcription factor ESE-3 is involved in the development of monocyte-derived DCs.

Appel, S., Bringmann, A., Grünebach, F., Weck, M., Bauer, J., & Brossart, P. (2006) · Blood · doi:10.1182/blood-2005-06-2480 · Cited by 28

Commitment of 1-Methyl-4-phenylpyrinidinium Ion-induced Neuronal Cell Death by Proteasome-mediated Degradation of p35 Cyclin-dependent Kinase 5 Activator

Endo, R., Saito, T., Asada, A., Kawahara, H., Ohshima, T., & Hisanaga, S. (2009) · Journal of Biological Chemistry · doi:10.1074/jbc.m109.026443 · Cited by 27

Short-hairpin RNA-mediated stable silencing of Grb2 impairs cell growth and DNA synthesis

Fulvio, M. D., Henkels, K. M., & Gómez-Cambronero, J. (2007) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2007.04.013 · Cited by 18

KLF6 Gene and Early Melanoma Development in a Collagen I-Rich Extracellular Environment

Huh, S. J., Chen, Y.-L., Friedman, S. L., Liao, J., Huang, H., Cavenee, W. K., & Robertson, G. P. (2010) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/djq218 · Cited by 16

Cell growth stimulation by CRASH, an asparaginase-like protein overexpressed in human tumors and metastatic breast cancers.

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CDK5 activator p35 downregulates E‐cadherin precursor independently of CDK5

Lin, S., Wang, J., Ye, Z., Ip, N. Y., & Lin, S. (2008) · FEBS Letters · doi:10.1016/j.febslet.2008.02.053 · Cited by 12

New mutations identified in the ocular albinism type 1 gene

Roma, C., Ferrante, P., Guardiola, O., Ballabio, A., & Zollo, M. (2007) · Gene · doi:10.1016/j.gene.2007.07.020 · Cited by 5

Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET

Peinado, H., Alečković, M., Lavotshkin, S., Matei, I., Costa-Silva, B., Moreno-Bueno, G., Hergueta-Redondo, M., Williams, C., García-Santos, G., Ghajar, C. M., et al. (2012) · Nature Medicine · doi:10.1038/nm.2753 · Cited by 3,715

Data-Driven Phenotypic Dissection of AML Reveals Progenitor-like Cells that Correlate with Prognosis

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Multi-Omics Factor Analysis—a framework for unsupervised integration of multi-omics data sets

Argelaguet, R., Velten, B., Arnol, D., Dietrich, S., Zenz, T., Marioni, J. C., Buettner, F., Huber, W., & Stegle, O. (2018) · Molecular Systems Biology · doi:10.15252/msb.20178124 · Cited by 1,510

Methods of integrating data to uncover genotype-phenotype interactions

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Next-Generation Machine Learning for Biological Networks

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Theory An Integrated Approach to Uncover Drivers of Cancer

Akavia, U. D., Litvin, O., Kim, J., Sanchez-Garcia, F., Kotliar, D., & Causton, H. C. (2014)

Abstract B70: Conexic: A Bayesian framework to detect drivers and their function uncovers an endosomal signature in melanoma

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Abstract SY17-02: A systems approach to understanding tumor specific drug response

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Cancer driver gene discovery through an integrative genomics approach in a non-parametric Bayesian framework

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Abstract 3958: Multi-Reg: An integrative parallel approach to uncover drivers of cancer

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