Systematic Discovery of TLR Signaling Components Delineates Viral-Sensing Circuits

Cited by (181)

Items 101–181 of 181

  1. Interactions of human galectins with Trypanosoma cruzi: Binding profile correlate with genetic clustering of lineages
    Miguel A. Pineda, Laura Corvo, Manuel Soto, Manuel Fresno, Pedro Bonay · 2014 · Glycobiology
  2. Multiple centrosomes enhance migration and immune cell effector functions of mature dendritic cells
    Ann-Kathrin Weier, Mirka Homrich, Stephanie Ebbinghaus, Pavel Jůda, Eliška Miková, Robert Hauschild, Lili Zhang, Thomas Quast, Elvira Mass, Andreas Schlitzer et al. · 2022 · The Journal of Cell Biology
  3. Recent strategies and progress in identifying host factors involved in virus replication
    Renate König, Silke Stertz · 2015 · Current Opinion in Microbiology
  4. TLR3-Mediated CD8+ Dendritic Cell Activation Is Coupled with Establishment of a Cell-Intrinsic Antiviral State
    Lajos Széles, Felix Meissner, Isabelle Dunand-Sauthier, Christoph Thelemann, Micha Hersch, Simon Singovski, Sergio Haller, Florian Gobet, Silvia A. Fuertes Marraco, Matthias Mann et al. · 2015 · The Journal of Immunology
  5. Validity of the MPTP-Treated Mouse as a Model for Parkinson’s Disease
    Cornelius J. H. M. Klemann, Gerard J.M. Martens, Geert Poelmans, Jasper E. Visser · 2015 · Molecular Neurobiology
  6. A systems framework for vaccine design
    Michael A. Mooney, Shannon K. McWeeney, Glenda Canderan, Rafick‐Pierre Sékaly · 2013 · Current Opinion in Immunology
  7. MicroRNA-376b-3p Promotes Porcine Reproductive and Respiratory Syndrome Virus Replication by Targeting Viral Restriction Factor TRIM22
    Jing Chen, Shijie Zhao, Zhiying Cui, Wen Li, Pengli Xu, Huimin Liu, Xinyong Miao, Yu Chen, Fangfang Han, Hongying Zhang et al. · 2021 · Journal of Virology
  8. Transcriptomic profiling of Tibetan highland fish (Gymnocypris przewalskii) in response to the infection of parasite ciliate Ichthyophthirius multifiliis
    Fei Tian, Chao Tong, Chenguang Feng, Kunyuan Wanghe, Kai Xuan Zhao · 2017 · Fish & Shellfish Immunology
  9. A Comprehensive Map of the Monocyte-Derived Dendritic Cell Transcriptional Network Engaged upon Innate Sensing of HIV
    Jarrod S. Johnson, Nicholas De Veaux, Alexander W. Rives, Xavier Lahaye, Sasha Y. Lucas, Brieuc P. Pérot, Marine Luka, Victor Garcia-Paredes, Lynn M. Amon, Aaron Watters et al. · 2020 · Cell Reports
  10. Systems Approaches towards Molecular Profiling of Human Immunity
    Julie G. Burel, Simon Hall Apte, Denise L. Doolan · 2015 · Trends in Immunology
  11. Polo-Like Kinase 1 (PLK1) Is Involved in Toll-like Receptor (TLR)-Mediated TNF-α Production in Monocytic THP-1 Cells
    Jinyue Hu, Guihua Wang, Xueting Liu, Lina Zhou, Manli Jiang, Yang Li · 2013 · PLoS ONE
  12. Molecular Mechanisms of Sepsis-Associated Acute Kidney Injury
    Takashi Hato, Pierre C. Dagher · 2025 · Journal of the American Society of Nephrology
  13. PLK1 inhibition dampens NLRP3 inflammasome–elicited response in inflammatory disease models
    Marta Baldrighi, Christian Doreth, Yang Li, Xiaohui Zhao, Emily F. Warner, Hannah Chenoweth, Kamal Kishore, Yagnesh Umrania, David‐Paul Minde, Sarah Thome et al. · 2023 · Journal of Clinical Investigation
  14. Systematically characterizing the roles of E3-ligase family members in inflammatory responses with massively parallel Perturb-seq
    Kathryn Geiger-Schuller, Basak Eraslan, Olena Kuksenko, Kushal K. Dey, Karthik A. Jagadeesh, Pratiksha I. Thakore, Özge Karayel, Andrea R. Yung, Anugraha R. Rajagopalan, Ana M. Meireles et al. · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
  15. Tumor Progression Locus 2 Promotes Induction of IFNλ, Interferon Stimulated Genes and Antigen-Specific CD8+ T Cell Responses and Protects against Influenza Virus
    Teneema Kuriakose, Ralph A. Tripp, Wendy Tharpe Watford · 2015 · PLoS Pathogens
  16. Understanding Th17 cells through systematic genomic analyses
    Anneli Peters, Nir Yosef · 2014 · Current Opinion in Immunology
  17. Analysis of Autofluorescence in Polymorphonuclear Neutrophils: A New Tool for Early Infection Diagnosis
    Antoine Monsel, Sandrine Lécart, Antoine Roquilly, Alexis H. Broquet, Cédric Jacqueline, Tristan Mirault, Thibaut Troude, Marie‐Pierre Fontaine‐Aupart, Karim Asehnoune · 2014 · PLoS ONE
  18. Antiviral innate immunity through the lens of systems biology
    Shashank Tripathi, Adolfo García‐Sastre · 2015 · Virus Research
  19. The multi-output incoherent feedforward loop constituted by the transcriptional regulators LasR and RsaL confers robustness to a subset of quorum sensing genes in Pseudomonas aeruginosa
    Roslen Bondì, Francesca Longo, Marco Messina, Francesca D’Angelo, Paolo Visca, Livia Leoni, Giordano Rampioni · 2017 · Molecular BioSystems
  20. Lipopolysaccharide Promotes Inflammatory Response via Enhancing IFIT1 Expression in Human Umbilical Vein Endothelial Cells
    Jiali Wang, Fen Cai, Xuehui Liu, Limin Li, Xin He, Xiumei Hu, Chun‐Min Kang, Huan‐Lan Bai, Ruyi Zhang, Chang-Meng Wu et al. · 2020 · DNA and Cell Biology
  21. Pan-cancer analysis of oncogenic TNFAIP2 identifying its prognostic value and immunological function in acute myeloid leukemia
    Meisi Lin, Hui-Yun Zhong, Rita Yim, Qiyan Chen, Hongling Du, Haoqi He, Ke Lin, Peng Zhao, Ru Gao, Fei Gao et al. · 2022 · BMC Cancer
  22. Diagnostic value of cytokines in severe childhood Mycoplasma pneumoniae pneumonia combined with Adenovirus infection
    Xiaowen Yi, Wanyu Jia, Wanying Li, Canyang Jia, Chunlan Song · 2024 · The Italian Journal of Pediatrics/Italian journal of pediatrics
  23. Identifying gnostic predictors of the vaccine response
    W. Nicholas Haining, Bali Pulendran · 2012 · Current Opinion in Immunology
  24. Genome-wide Chromatin Profiling ofLegionella pneumophila–Infected Human Macrophages Reveals Activation of the Probacterial Host Factor TNFAIP2
    Ilona Du Bois, Annalisa Marsico, Wilhelm Bertrams, Michal R. Schweiger, Brian Edward Caffrey, Alexandra Sittka-Stark, Martin Eberhardt, Julio Vera, Martin Vingron, Bernd Schmeck · 2016 · The Journal of Infectious Diseases
  25. Signaling events induced by lipopolysaccharide-activated Toll in response to bacterial infection in shrimp
    Sheng Wang, Haoyang Li, Qinyao Li, Bin Yin, Sedong Li, Jianguo He, Chaozheng Li · 2023 · Frontiers in Immunology
  26. Interleukin-1 and Interferon-γ Orchestrate β-Glucan-Activated Human Dendritic Cell Programming via IκB-ζ Modulation
    Marco Cardone, Amiran Dzutsev, Hongchuan Li, Nicolas Riteau, Franca Gerosa, Kevin Shenderov, Robin T. Winkler-Pickett, Lisa Provezza, Elena Riboldi, Robert M. Leighty et al. · 2014 · PLoS ONE
  27. Highlights of the advances in basic immunology in 2011
    Juan Liu, Shuxun Liu, Xuetao Cao · 2012 · Cellular and Molecular Immunology
  28. Systems approaches to human autoimmune diseases
    Romain Banchereau, Alma‐Martina Cepika, Virginia Pascual · 2013 · Current Opinion in Immunology
  29. M-sec regulates polarized secretion of inflammatory endothelial chemokines and facilitates CCL2-mediated lymphocyte transendothelial migration
    Sagi Barzilai, Ronnie Blecher‐Gonen, Zohar Barnett‐Itzhaki, Ayelet Zauberman, Yaeli Lebel-Haziv, Ido Amit, Ronen Alon · 2015 · Journal of Leukocyte Biology
  30. Genome-wide siRNA screen of genes regulating the LPS-induced TNF-α response in human macrophages
    Jing Sun, Samuel Katz, Bhaskar Dutta, Ze Wang, Iain D. C. Fraser · 2017 · Scientific Data
  31. Translation of TNFAIP2 is tightly controlled by upstream open reading frames
    Anica Scholz, Peter Rappl, Nicola Martina Böffinger, Ana Carolina Mota, Bernhard Brüne, Tobias Schmid · 2019 · Cellular and Molecular Life Sciences
  32. Decoding dendritic cell function through module and network analysis
    Gaurav Shankar Pandey, Ariella T. Cohain, Jennifer C. Miller, Miriam Mérad · 2012 · Journal of Immunological Methods
  33. Collective behaviors of mammalian cells on amine-coated silicon nanowires
    So Yeon Kim, Eun Gyeong Yang · 2013 · Nanotechnology
  34. Suppression of interferon β gene transcription by inhibitors of bromodomain and extra-terminal (BET) family members
    Nazma Malik, Stefan Vollmer, Sambit K. Nanda, Marta López‐Peláez, Alan R. Prescott, Nathanael S. Gray, Philip Cohen · 2015 · Biochemical Journal
  35. TimeXNet: Identifying active gene sub-networks using time-course gene expression profiles
    Ashwini Patil, Kenta Nakai · 2014 · BMC Systems Biology
  36. Type I and III Interferon Productions Are Impaired in X-Linked Agammaglobulinemia Patients Toward Poliovirus but Not Influenza Virus
    Anderson Dik Wai Luk, Ke Ni, Yuet Wu, Kwok-Tai Lam, Koon Wing Chan, Pamela P. W. Lee, Wenwei Tu, Huawei Mao, YL Lau · 2018 · Frontiers in Immunology
  37. Polo-like kinase 2 promotes microglial activation via regulation of the HSP90α/IKKβ pathway
    Junjie Cheng, Lei Wu, Xiaowan Chen, Shuai Li, Zhirou Xu, Renjuan Sun, Yiwei Huang, Peng Wang, Jiawei Ouyang, Panpan Pei et al. · 2024 · Cell Reports
  38. Exposure to microbial products followed by loss of Tet2 promotes myelodysplastic syndrome via remodeling HSCs
    Takako Yokomizo‐Nakano, Ai Hamashima, Sho Kubota, Jie Bai, Supannika Sorin, Yuqi Sun, Kenta Kikuchi, Mihoko Iimori, Mariko Morii, Akinori Kanai et al. · 2023 · The Journal of Experimental Medicine
  39. The DIONESUS algorithm provides scalable and accurate reconstruction of dynamic phosphoproteomic networks to reveal new drug targets
    Mark F. Ciaccio, Vincent C. Chen, Richard Baker Jones, Neda Bagheri · 2015 · Integrative Biology
  40. microRNA-Mediated Encoding and Decoding of Time-Dependent Signals in Tumorigenesis
    Simone Tealdi, Elsi Ferro, Carlo Cosimo Campa, Carla Bosia · 2022 · Biomolecules
  41. Foot-and-Mouth Disease Virus Capsid Protein VP1 Antagonizes TPL2-Mediated Activation of the IRF3/IFN-β Signaling Pathway to Facilitate the Virus Replication
    Junhong Hao, Chaochao Shen, Nannan Wei, Minghao Yan, Xuegang Zhang, Guowei Xu, Dajun Zhang, Jing Hou, Weijun Cao, Jin Ye et al. · 2021 · Frontiers in Immunology
  42. Uptake of nanowires by human lung adenocarcinoma cells
    Laura Abariūtė, Mercy Lard, Elke Hebisch, Christelle N. Prinz · 2019 · PLoS ONE
  43. Genome-wide siRNA screen of genes regulating the LPS-induced NF-κB and TNF-α responses in mouse macrophages
    Ning Li, Samuel Katz, Bhaskar Dutta, Zachary L. Benet, Jing Sun, Iain D. C. Fraser · 2017 · Scientific Data
  44. Regulation of PKR-dependent RNA translation inhibition by TRIM21 upon virus infection or other stress
    Huiyi Li, Shun Liu, Qing Feng, Rilin Deng, Jingjing Wang, Xintao Wang, Renyun Tian, Yan Xu, Shengwen Chen, Qian Liu et al. · 2023 · PLoS Pathogens
  45. m6A methylation dynamically participates in the immune response against Vibrio anguillarum in half-smooth tongue sole (Cynoglossus semilaevis)
    Suxu Tan, Wenwen Wang, Sen Han, Ruixue Zhang, Kunpeng Shi, Shaoqing Zang, Zhendong Wu, Zhenxia Sha · 2024 · Fish & Shellfish Immunology
  46. Putative link between Polo-like kinases (PLKs) and Toll-like receptor (TLR) signaling in transformed and primary human immune cells
    Souhayla El Maadidi, Alexander N.R. Weber, Precious G. Motshwene, Moritz Schüssler, Daniel Backes, Sabine Dickhöfer, Hui Wang, Xiao Liu, Magno Delmiro Garcia, Christoph Täumer et al. · 2019 · Scientific Reports
  47. Charting protein dephosphorylation triggered by Toll-like receptor (TLR) signaling in macrophages and its role in health and disease
    Aristóbolo M. Silva, Thomas S. Postler · 2021 · International review of cytology
  48. Topology, dynamics, and heterogeneity in immune signaling
    J. Taylor Webb, Marcelo Behar · 2015 · WIREs Systems Biology and Medicine
  49. Multiomics and Systems Biology Are Needed to Unravel the Complex Origins of Chronic Disease
    David Martino, Rym Ben-Othman, Danny J. Harbeson, Anthony Bosco · 2019 · Challenges
  50. Omics and systems view of innate immune pathways
    Deepali Rathore, Matthew J. Marino, Aleksandra Nita‐Lazar · 2023 · PROTEOMICS
  51. Microwestern Arrays for Systems-Level Analysis of SH2 Domain-Containing Proteins
    Mark F. Ciaccio, Richard Baker Jones · 2017 · Methods in molecular biology
  52. TIR-Domain-Containing Adapter-Inducing Interferon-β (TRIF)-Dependent Antiviral Responses Protect Mice against Ross River Virus Disease
    Xiang Liu, Adam Taylor, Yee Suan Poo, Wern Hann Ng, Lara J. Herrero, Patrick Chun Hean Tang, Ali Zaid, Suresh Mahalingam · 2022 · mBio
  53. From data to discovery: AI-guided analysis of disease-relevant molecules in spinal muscular atrophy (SMA)
    Ines Tapken, Daniela Kühn, Nico Hoffmann, Nora Tula Detering, Tobias Schüning, Jean-Noël Billaud, Stuart Tugendreich, Nadine Schlüter, Jeff Green, A. Krämer et al. · 2024 · Human Molecular Genetics
  54. Integrated interactome and transcriptome analysis reveals key host factors critical for SARS-CoV-2 infection
    Jie Sheng, Lili Li, Xueying Lv, Meiling Gao, Ziyi Chen, Zhuo Long Zhou, Jingfeng Wang, Aiping Wu, Taijiao Jiang · 2023 · Virologica Sinica
  55. Interfacing Biology Systems with Nanoelectronics for Nanodevices
    Loutfy H. Madkour · 2019 · Advanced structured materials
  56. Nanotechnologies for the Bioelectronic Interface
    Benjamin W. Avants, Hongkun Park, Jacob T. Robinson · 2016 · Wiley eBooks
  57. A Chemical Proteomics Approach to Discover Regulators of Innate Immune Signaling
    Andrew P. Kurland, Boris Bonaventure, Jeffrey R. Johnson · 2023 · Viruses
  58. Systems Immunology
    Melissa Lever, Thiago Dominguez Crespo Hirata, Pedro S. T. Russo, Helder Imoto Nakaya · 2018 · Computational biology
  59. Approaching complexity: systems biology and ms-based techniques to address immune signaling
    Joseph Gillen, Caleb Bridgwater, Aleksandra Nita‐Lazar · 2020 · Expert Review of Proteomics
  60. m6A methylation dynamically participates in the immune response against Vibrio anguillarum in half-smooth tongue sole ( Cynoglossus semilaevis )
    Suxu Tan, Wenwen Wang, Sen Han, Kunpeng Shi, Shaoqing Zang, Zhendong Wu, Zhenxia Sha · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
  61. Susceptibility of TNFAIP8 , TNFAIP8L1 , and TNFAIP2 Gene Polymorphisms on Cancer Risk: A Comprehensive Review and Meta-Analysis of Case–Control Studies
    Khokon Kanti Bhowmik, Md Abdul Barek, Md. Abdul Aziz, Mohammad Safiqul Islam · 2022 · Technology in Cancer Research & Treatment
  62. Regulation of oxidoreductase enzymes during inflammation
    Sonia Ingram · 2018
  63. Systems Immunology
    Mark M. Davis, Shai S. Shen-Orr · 2012 · Elsevier eBooks
  64. Genomic Approaches to Dissect Innate Immune Pathways
    Mark N. Lee · 2013 · Digital Access to Scholarship at Harvard (DASH) (Harvard University)
  65. Nanowire Biosensors
    John F. Zimmerman, Bozhi Tian · 2014 · Royal Society of Chemistry eBooks
  66. Electrical interfacing of nanowire devices with cells and tissues
    M. Paul, Graeme F. Murray, Bozhi Tian · 2015 · Elsevier eBooks
  67. Dynamic profiling of the protein life cycle in response to pathogens
    Marko Jovanović, P. Mertins, Dariusz Przybylski, Nicolas Chevrier, R. Satija, Edwin H. Rodriguez, Alexander P. Fields, Schraga Schwartz, Raktima Raychowdhury, Max Mumbach et al. · 2014 · DSpace@MIT (Massachusetts Institute of Technology)
  68. Pairwise Interactions in Adjuvant Combinations Dictate Immune Responses and Inform Cancer Immunotherapy Design
    Surya Pandey, Adam Gruenbaum, Tamara Kanashova, Philipp Mertins, Philippe Cluzel, Nicolas Chevrier · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
  69. Faculty Opinions recommendation of Perturb-Seq: Dissecting Molecular Circuits with Scalable Single-Cell RNA Profiling of Pooled Genetic Screens.
    Roderic Guigó · 2018 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
  70. Regulation of protein translation by TRIM21
    Huiyi Li, Shun Liu, Qing Feng, Rilin Deng, Jingjing Wang, Xintao Wang, Renyun Tian, Yan Xu, Shengwen Chen, Qian Liu et al. · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
  71. Nanobiotechnology
    2022 · Wiley eBooks
  72. Additional file 1 of Pan-cancer analysis of oncogenic TNFAIP2 identifying its prognostic value and immunological function in acute myeloid leukemia
    Meisi Lin, Hui-Yun Zhong, Rita Yim, Qiyan Chen, Hongling Du, Haoqi He, Ke Lin, Peng Zhao, Ru Gao, Fei Gao et al. · 2022 · Figshare
  73. Pediatrics advances in 2024: choices in allergy, cardiology, critical care, endocrinology, gastroenterology, immunology, infectious diseases, neonatology, nephrology, neurology, nutrition, palliative care respiratory tract illnesses, and social media
    Carlo Caffarelli, Elena Bozzola, Ettore Piro, Bertrand Tchana, Enrico Vito Buono, Daniela Cunico, Sergio Bernasconi, Giovanni Corsello · 2025 · The Italian Journal of Pediatrics/Italian journal of pediatrics
  74. Additional file 5 of Pan-cancer analysis of oncogenic TNFAIP2 identifying its prognostic value and immunological function in acute myeloid leukemia
    Meisi Lin, Zhong, Hui-Yun, Rita Yim, Chen, Qi-Yan, Du, Hong-ling, He, Hao-qi, Lin, Ke, Zhao, Peng, Gao, Ru, Gao, Fei et al. · 2022 · Figshare
  75. Additional file 4 of Pan-cancer analysis of oncogenic TNFAIP2 identifying its prognostic value and immunological function in acute myeloid leukemia
    Meisi Lin, Zhong, Hui-Yun, Rita Yim, Chen, Qi-Yan, Du, Hong-ling, He, Hao-qi, Lin, Ke, Zhao, Peng, Gao, Ru, Gao, Fei et al. · 2022 · Figshare
  76. Additional file 2 of Pan-cancer analysis of oncogenic TNFAIP2 identifying its prognostic value and immunological function in acute myeloid leukemia
    Meisi Lin, Zhong, Hui-Yun, Rita Yim, Chen, Qi-Yan, Du, Hong-ling, He, Hao-qi, Lin, Ke, Zhao, Peng, Gao, Ru, Gao, Fei et al. · 2022 · Figshare
  77. Additional file 3 of Pan-cancer analysis of oncogenic TNFAIP2 identifying its prognostic value and immunological function in acute myeloid leukemia
    Meisi Lin, Zhong, Hui-Yun, Rita Yim, Chen, Qi-Yan, Du, Hong-ling, He, Hao-qi, Lin, Ke, Zhao, Peng, Gao, Ru, Gao, Fei et al. · 2022 · Figshare
  78. Rôle immunorégulateur de la protéine GILZ dans les cellules dendritiques pendant l’infection virale chronique par le VIH-1 et perspectives dans des stratégies vaccinales
    Thomas Barbin · 2017 · theses.fr (ABES)
  79. The Molecular Machinery of Synaptic Plasticity and Its Potential Role in the Aetiology of Schizophrenia
    BRIAN J. MORRIS · 2026 · Molecular Neurobiology
  80. miRNA delivery via nanowires restores functional responses in aged T cells
    Zhonghao Dai, Shaylyn Grier, Zhe Zhong, Ameya Dravid, Joscelyn C. Mejías, Jean Louise Koff, Andrés J. Garcı́a, Ankur K. Singh · 2026 · Cell Biomaterials
  81. Response of human MDDCs to HIV
    Mickael Menager, Jarrod Johnson, Nicholas De Veaux, Alexander Rives, Lynn Amon, Nicolas Manel, Alan Aderem, Dan Littman, Richard Bonneau · 2021 · ImmPort