A Vitamin D Receptor/SMAD Genomic Circuit Gates Hepatic Fibrotic Response

Ding, Ning, Yu, Ruth T., Subramaniam, Nanthakumar, Sherman, Mara H., Wilson, Caroline, Rao, Renuka, Leblanc, Mathias, Coulter, Sally, He, Mingxiao, Scott, Christopher, Lau, Sue L., Atkins, Annette R., Barish, Grant D., Gunton, Jenny E., Liddle, Christopher, Downes, Michael, Evans, Ronald M.·2013·Cell

DOI 10.1016/j.cell.2013.03.028

Cited by (622)

Items 401–500 of 622

Absence of vitamin D receptor (VDR)‐mediated PPARγ suppression causes alopecia in VDR‐null mice
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Differential modulation of hepatitis C virus replication and innate immune pathways by synthetic calcitriol-analogs
Maged Saleh, Christoph Welsch, Chengcong Cai, Claudia Döring, Jérôme Gouttenoire, Judith Friedrich, Katrin Haselow, Christoph Sarrazin, Klaus W. J. Badenhoop, Darius Moradpour et al. · 2018 · The Journal of Steroid Biochemistry and Molecular Biology
A Lipid-Based Nanocarrier Containing Active Vitamin D3 Ameliorates NASH in Mice via Direct and Intestine-Mediated Effects on Liver Inflammation
Yunmei Mu, Jinting Li, Jeong‐Hun Kang, Hinako Eto, Khadijah Zai, Akihiro Kishimura, Fuminori Hyodo, Takeshi Mori, Yoshiki Katayama · 2020 · Biological and Pharmaceutical Bulletin
Effect of vitamin D supplementation in patients with chronic hepatitis C after direct-acting antiviral treatment: a randomized, double-blind, placebo-controlled trial
Supachaya Sriphoosanaphan, Kessarin Thanapirom, Stephen John Kerr, Sirinporn Suksawatamnuay, Panarat M. Thaimai, Sukanya Sittisomwong, Kanokwan Sonsiri, Nunthiya Srisoonthorn, Nicha Teeratorn, Natthaporn Tanpowpong et al. · 2021 · PeerJ
Overview of studies of the vitamin D/vitamin D receptor system in the development of non-alcoholic fatty liver disease
Flavia Agata Cimini, Ilaria Barchetta, Simone Carotti, Sergio Morini, Maria Gisella Cavallo · 2019 · World Journal of Gastrointestinal Pathophysiology
SIRT7 affects autophagy and activation of hepatic stellate cells by regulating the acetylation level of high mobility group protein 1
Zhi-Hua Xiao, Zhengyuan Xie, Qing Wang, Hui Juan Lu, Heng-Wei Cao · 2022 · Immunobiology
The Influence of Single Nucleotide Polymorphisms on Vitamin D Receptor Protein Levels and Function in Chronic Liver Disease
Evanthia Tourkochristou, Efthymios P. Tsounis, Haralampos Tzoupis, Ioanna Aggeletopoulou, Aggeliki Tsintoni, Theoni Lourida, Γεωργία Διαμαντοπούλου, Konstantinos Zisimopoulos, Theodora Kafentzi, Anne-Lise de Lastic et al. · 2023 · International Journal of Molecular Sciences
The chromatin remodeling protein BRG1 regulates HSC-myofibroblast differentiation and liver fibrosis
Yuwen Zhu, Aoqi Kang, Yameng Kuai, Yan Guo, Xiulian Miao, Li Zhu, Ming Kong, Nan Li · 2023 · Cell Death and Disease
25(OH) D3 alleviate liver NK cytotoxicity in acute but not in chronic fibrosis model of BALB/c mice due to modulations in vitamin D receptor
Ahmad Salhab, Johnny Amer, Yinying Lu, Rifaat Safadi · 2020 · BMC Gastroenterology
Bioinformatic approaches to interrogating vitamin D receptor signaling
Moray J. Campbell · 2017 · Molecular and Cellular Endocrinology
Reversing Epigenetic Alterations Caused by Alcohol: A Promising Therapeutic Direction for Alcoholic Liver Disease
Xiu‐Xian Lin, Guanghui Lian, Shifang Peng, Qing Zhao, Ying Xu, Dongsheng Ouyang, Wei Zhang, Yao Chen · 2018 · Alcoholism Clinical and Experimental Research
Discovery of fused bicyclic derivatives of 1H-pyrrolo[1,2-c]imidazol-1-one as VDR signaling regulators
Bin Xu, Mo‐Yu Ding, Zhibing Weng, Zheng-Qing Li, Feng Li, Xia Sun, Qiuling Chen, Yitao Wang, Ying Wang, Guo‐Chun Zhou · 2019 · Bioorganic & Medicinal Chemistry
Cholangiopathy aggravation is caused by VDR ablation and alleviated by VDR-independent vitamin D signaling in ABCB4 knockout mice
Ester Gonzalez‐Sanchez, Haquima El Mourabit, Marion Jäger, Marie-Annick A Clavel, Sophie Moog, Javier Vaquero, Tatiana Ledent, Axelle Cadoret, Jérémie Gautheron, Laura Fouassier et al. · 2021 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
From Influenza Virus Infections to Lupus: Synchronous Estrogen Receptor α and RNA Polymerase II Binding Within the Immunoglobulin Heavy Chain Locus
Bart G. Jones, Robert E. Sealy, Rhiannon R. Penkert, Sherri L. Surman, Barbara K. Birshtein, Beisi Xu, Geoffrey A. M. Neale, Robert W. Maul, Patricia J. Gearhart, Julia L. Hurwitz · 2020 · Viral Immunology
Illuminating liver fibrosis with vitamin D
Delphine Firrincieli, Thomas Braescu, Chantal Housset, Nicolas Chignard · 2013 · Clinics and Research in Hepatology and Gastroenterology
Frontline Science: Concanavalin A-induced acute hepatitis is attenuated in vitamin D receptor knockout mice with decreased immune cell function
Naoki Umeda, Kaori Endo‐Umeda, Hiroyuki Nakashima, Shigeaki Kato, Shuhji Seki, Makoto Makishima · 2019 · Journal of Leukocyte Biology
Changes in hepatic fibrosis and vitamin D levels after viral hepatitis C eradication using direct-acting antiviral therapy
Supachaya Sriphoosanaphan, Kessarin Thanapirom, Sirinporn Suksawatamnuay, Panarat M. Thaimai, Sukanya Sittisomwong, Kanokwan Sonsiri, Nunthiya Srisoonthorn, Nicha Teeratorn, Nattaporn Tanpowpong, Bundit Chaopathomkul et al. · 2020 · BMC Gastroenterology
Cytokine Production and Signaling in Stellate Cells
Fabio Marra, Alessandra Caligiuri · 2015 · Elsevier eBooks
Decreased circulating vitamin D reflects adverse outcomes of hepatitis C virus infection: A systematic review and meta-analysis
Wanvisa Udomsinprasert, Jiraphun Jittikoon, Sorraya Sukkho, Nicha Pojarassangkul, Sermsiri Sangroongruangsri, Usa Chaikledkaew · 2020 · Journal of Infection
Ameliorative effects of Qingganjiuwei powder, a traditional Mongolian medicine, against CCl4-induced liver fibrosis in rats
Hongyan Ge, Anqing Wang, Ya Su, Chunlei Yu, Lu Gao, Yuxin Li · 2020 · Journal of Ethnopharmacology
Roles of nuclear receptors in hepatic stellate cells
Shiyun Pu, Hongjing Zhou, Yan Liu, Jiao Liu, Yuanxin Guo, Houfeng Zhou · 2021 · Expert Review of Gastroenterology & Hepatology
Impaired bile acid handling and aggravated liver injury in mice expressing a hepatocyte-specific RXRα variant lacking the DNA-binding domain
Astrid Kosters, Julio C. Felix, Moreshwar S. Desai, Saul J. Karpen · 2013 · Journal of Hepatology
Design, synthesis, and anti-liver fibrosis activity of novel non-steroidal vitamin D receptor agonists based on open-ring steroid scaffold
Fei Gao, Chun Guan, Nuo Cheng, Yichen Liu, Yue Wu, Bingyue Shi, Jiayi Huang, Sitong Li, Yu Tong, Yi Gao et al. · 2025 · European Journal of Medicinal Chemistry
Bromodomain protein 4 is a key molecular driver of TGFβ1-induced hepatic stellate cell activation
Feifan Xu, Sidan Lu, Nachuan Pan, Feifei Zhao, Xin Jia, Shouwei Wang, Yali Zhang, Yajun Zhou · 2023 · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
TGF-β1 stimulation and VDR-dependent activation modulate calcitriol action on skeletal muscle fibroblasts and Smad signalling-associated fibrogenesis
Ratchakrit Srikuea, Muthita Hirunsai · 2023 · Scientific Reports
New Roles for Vitamin D Superagonists: From COVID to Cancer
David J. Easty, Christine J. Farr, Bryan T. Hennessy · 2021 · Frontiers in Endocrinology
Skeletal and hepatic changes induced by chronic vitamin A supplementation in cats
Ronald Jan Corbee, Marianna A. Tryfonidou, Guy C. M. Grinwis, Baukje A. Schotanus, Martijn R. Molenaar, George Voorhout, Arie B. Vaandrager, Henri C. M. Heuven, Herman A.W. Hazewinkel · 2014 · The Veterinary Journal
Effect of Vitamin D Serum Levels and GC Gene Polymorphisms in Liver Fibrosis Due to Chronic Hepatitis C
Laura Alencastro de Azevedo, Úrsula da Silveira Matte, Themis Reverbel da Silveira, Jacqueline Weis Bonfanti, Juliana Paula BRUCH, Mário Reis Álvares‐da‐Silva · 2017 · Annals of Hepatology
Higher Serum 25-Hydroxyvitamin D Is Associated with Lower All-Cause and Cardiovascular Mortality among US Adults with Nonalcoholic Fatty Liver Disease
Yuxiong Chen, Siqin Feng, Zhen’ge Chang, Yakun Zhao, Yanbo Liu, Jia Fu, Yijie Liu, Siqi Tang, Yitao Han, Shuyang Zhang et al. · 2022 · Nutrients
Design, synthesis and anti-hepatic fibrosis activity of novel diphenyl vitamin D receptor agonists
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Vitamin D receptor agonists inhibit liver fibrosis by disrupting the interaction between hepatic stellate cells and neutrophil extracellular traps
Xuwentai Liu, Yue Wu, Chun Guan, Nuo Cheng, Xueting Wang, Yichen Liu, Jihai Chen, Cong Wang · 2025 · Biochemical Pharmacology
Role of Vitamin D Supplementation in Chronic Liver Disease: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Petrana Martineková, Mahmoud Obeidat, Mihaela Topala, Szilárd Váncsa, Dániel Sándor Veres, Ádám Zolcsák, Miheller Pál, László Földvári-Nagy, Peter Bánovčin, Bálint Mihály Erőss et al. · 2025 · Nutrition Reviews
Proteomic-genomic adjustments and their confluence for elucidation of pathways and networks during liver fibrosis
Hadiya Husain, Riaz Ahmad, Anish Khan, Inamuddin Inamuddin, Abdullah Mohamed Asiri · 2018 · International Journal of Biological Macromolecules
Antifibrotic Effects of 1,25(OH)2D3 on Nonalcoholic Steatohepatitis in Female Mice
Lingyun Ma, Masatoshi Ishigami, Takashi Honda, Shinya Yokoyama, Kenta Yamamoto, Yoji Ishizu, Teiji Kuzuya, Kazuhiko Hayashi, Yoshiki Hirooka, Hidemi Goto · 2019 · Digestive Diseases and Sciences
Photoaging Protective Effects of Ranunculus bulumei Methanol Extract
Yo Han Hong, Ji Hye Kim, Jae Youl Cho · 2020 · Evidence-based Complementary and Alternative Medicine
Repeated acute stress modulates hepatic inflammation and markers of macrophage polarisation in the rat
Jereme G. Spiers, Natasha Steiger, Arun Khadka, Juliani Juliani, Andrew Francis Hill, Nickolas A. Lavidis, Stephen T. Anderson, Hsiao‐Jou Cortina Chen · 2020 · Biochimie
Liganded Vitamin D Receptor Through Its Interacting Repressor Inhibits the Expression of Type I Collagen α1
Lin‐Yan Wan, Yanqiong Zhang, Junming Li, He-Qing Tang, Meng-Di Chen, Yi‐Ran Ni, He Huang, Chang-Bai Liu, Jiangfeng Wu · 2016 · DNA and Cell Biology
Regulation of the CCN genes by vitamin D: A possible adjuvant therapy in the treatment of cancer and fibrosis
Richard T. Piszczatowski, Nathan H. Lents · 2016 · Cellular Signalling
Nano‐calcipotriol as a potent anti‐hepatic fibrosis agent
Yina Zhang, Liying Wang, Jiajia Shao, Yanning Liu, Yining Lu, Jing Yang, Siduo Xu, Jingkang Zhang, Minwei Li, Xiangrui Liu et al. · 2023 · MedComm
The effect of high oral loading dose of cholecalciferol in non-alcoholic fatty liver disease patients. A randomized placebo controlled trial
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Vitamin D3 analogue calcipotriol inhibits the profibrotic effects of transforming growth factor- β1 on pancreatic stellate cells
Meifang Zheng, Hongyan Li, Yanhang Gao, David R. Brigstock, Runping Gao · 2023 · European Journal of Pharmacology
The regulatory role and mechanism of exosomes in hepatic fibrosis
Youli Yao, Da Chen, Zengchang Yue · 2023 · Frontiers in Pharmacology
Aging and a long-term diabetes mellitus increase expression of 1 α-hydroxylase and vitamin D receptors in the rat liver
Ana Vuica, Lejla Ferhatović Hamzić, Katarina Vukojević, Milka Jerić, Livia Puljak, Ivica Grković, Natalija Filipović · 2015 · Experimental Gerontology
RETRACTED: Ameliorative potential of linagliptin and/or calcipotriol onbleomycin-induced lung fibrosis: In vivo and in vitro study
Ahmed M. Kabel, Maaly A. Abd Elmaaboud, Aliaa Atef, Mohammed H. Baali · 2017 · Environmental Toxicology and Pharmacology · Retracted
The role of vitamin D receptor polymorphisms in the course of chronic hepatitis C infection
Efthymios P. Tsounis · 2022 · Annals of Gastroenterology
Cumulative Erythemal Ultraviolet Radiation and Risk of Cancer in 3 Large US Prospective Cohorts
Michael S. Chang, Rebecca Ivy Hartman, Nicole Trepanowski, Edward L. Giovannucci, Hongmei Nan, Xin Li · 2022 · American Journal of Epidemiology
Antagonizing EZH2 combined with vitamin D3 exerts a synergistic role in anti‐fibrosis through bidirectional effects on hepatocytes and hepatic stellate cells
Qinghui Zhang, Rongrong Jia, Minjie Chen, Jianjun Wang, Feng Huang, Min Shi, Huiming Sheng, Ling Xu · 2023 · Journal of Gastroenterology and Hepatology
Overexpression of GSN could decrease inflammation and apoptosis in EAE and may enhance vitamin D therapy on EAE/MS
Ji-Fang Gao, Zhaoyu Qin, Xin-Yuan Guan, Juan-juan Guo, Hua-Qing Wang, Shi-Lian Liu · 2017 · Scientific Reports
Vitamin D Signaling in Gastro-Rheumatology: From Immuno-Modulation to Potential Clinical Applications
Cristiano Pagnini, Andrea Picchianti Diamanti, Vincenzo Bruzzese, Roberto Lorenzetti, Michele Maria Luchetti, L.S. Martin Martin, Roberta Pica, Palma Scolieri, Maria Lia Scribano, Costantino Zampaletta et al. · 2021 · International Journal of Molecular Sciences
RAB18 modulates autophagy in human stellate cells
Soumik BasuRay · 2019 · Journal of clinical lipidology
Harnessing nuclear receptors to modulate hepatic stellate cell activation for liver fibrosis resolution
Yaxin Sun, Xiaoyan Yuan, Zhenhua Hu, Yuanyuan Li · 2024 · Biochemical Pharmacology
Ginsenoside AD-2 Ameliorating Lipopolysaccharide-Induced Activation in HSC-T6 Cells and Carbon Tetrachloride-Induced Hepatic Fibrosis in Mice via Regulation of VD-VDR Axis
Yu Chen, Lizhen Lin, Chunhong Yang, Tao Li, Yuan Li, Jian Wang, Yan‐Ling Wu, Yuqing Zhao, Guangyue Su · 2023 · Journal of Agricultural and Food Chemistry
Vitamin D Receptor Regulates Liver Regeneration After Partial Hepatectomy in Male Mice
Harendran Elangovan, Rebecca Stokes, Jeremy Keane, Sarinder Chahal, Caroline Flora Samer, Miguel Agoncillo, Josephine Yu, Jennifer Chen, Michael Downes, Ronald M. Evans et al. · 2024 · Endocrinology
Unorthodox Transcriptional Mechanisms of Lipid-Sensing Nuclear Receptors in Macrophages: Are We Opening a New Chapter?
Zsolt Czimmerer, László Halász, László Nagy · 2020 · Frontiers in Endocrinology
A New Modified Experimental Meibomian Gland Injury Model: Partial Loss of Gland Due to Orifice Cauterization and the Alleviating Potential of 22-Oxacalcitriol
Kai Jin, Motoko Kawashima, Masataka Ito, Reiko Arita, Kokoro Sano, Kazuo Tsubota · 2020 · Journal of Clinical Medicine
Relationship of Vitamin D Deficiency and Fatty Liver in Children as Defined by Multiple Imaging and Histologic Endpoints
Bryan Rudolph, Tyler M. Selig, Yingjie Li, Nadia Ovchinsky, Debora Kogan‐Liberman, Mark C. Liszewski, Terry L. Levin, Michelle R. Ewart, Qiang Liu, V. Shankar et al. · 2021 · JPGN Reports
Cancer-associated fibroblasts in neoadjuvant setting for solid cancers
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Cardiac effect of vitamin D receptor modulators in uremic rats
Masahide Mizobuchi, Etsuro Ogata, Ai Yamazaki-Nakazawa, Nozomu Hosaka, Fumiko Kondo, Fumihiko Koiwa, Eriko Kinugasa, Takanori Shibata · 2016 · The Journal of Steroid Biochemistry and Molecular Biology
The Incidental Use of High-Dose Vitamin D3 in Pancreatic Cancer
Timothy Lewis Cannon, Joel Ford, Danubia Hester, Donald L. Trump · 2016 · Case Reports in Pancreatic Cancer
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Lei Xiao, Hua Zhang, Xin Nian Yang, Shaya Mahati, Ge Wu, Xiaheding Yiliyaer, Yongxing Bao, Hui Xiao · 2020 · The Kaohsiung Journal of Medical Sciences
Vitamin D Attenuates Non-Alcoholic Fatty Liver Disease in High-Fat Diet-Induced Obesity Murine Model
Sook In Chung, Lin Liang, Heejae Han, Kyung Hee Park, Jae-Hyun Lee, Jung‐Won Park · 2024 · Yonsei Medical Journal
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B cell deficiency limits exercise capacity by remodeling liver glutamate metabolism
Youxiang Mao, Ziyan Xia, Xu Pan, Wenjun Xia, Peng Jiang · 2026 · Cell
Expression pattern of CYP24 in liver during ageing in long-term diabetes
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Vitamin D 3 exacerbates steatosis while calcipotriol inhibits inflammation in non-alcoholic fatty liver disease in Sod1 knockout mice: a comparative study of two forms of vitamin D
Aolin Yang, Yanmei Chen, Yizhen Gao, Qingqing Lv, Yao Li, Fengna Li, Ruirui Yu, Ziyu Han, Shimiao Dai, Junying Zhu et al. · 2024 · Food & Function
Comparison of the role of vitamin D in normal organs and those affected by COVID-19
Peramaiyan Rajendran, Anthony Josephine, Sureka Varalakshmi, Ashok Kumar Sekar, Enas Mohamed Ali, Sallah A. Al‐Hashedi, Basem M. Abdallah · 2024 · International Journal of Medical Sciences
Genome-Wide Perspectives on Vitamin D Receptor–Mediated Control of Gene Expression in Target Cells
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VDR rs7975232/ApaI genetic variation predicts sustained HBsAg loss in HBeAg‐positive chronic hepatitis B patients treated with pegylated interferon
Ben Shan, Jun Yan Wang, Xia Wang, Juan Fu, Li Li, Xiucheng Pan, Jian Jun Li, Xian Tuan Tang · 2018 · Journal of Medical Virology
SMAD3 interacts with vitamin D receptor and affects vitamin D‐mediated oxidative stress to ameliorate cerebral ischaemia–reperfusion injury
Hang Yu, Yuxiang Xie, Mingming Dai, Yuxiang Pan, Chengzhi Xie · 2022 · European Journal of Neuroscience
Serum vitamin D status in sick cats with and without cholestatic liver disease
Lesli N. Kibler, Cailin R. Heinze, Cynthia R. L. Webster · 2020 · Journal of Feline Medicine and Surgery
PYCR1-dependent proline synthesis in cancer-associated fibroblasts is required for the deposition of pro-tumorigenic extracellular matrix
Emily Jane Kay, Karla Paterson, Carla Riero Domingo, David P. Sumpton, Henry Daebritz, Saverio Tardito, Claudia Boldrini, Juan Ramon Hernandez-Fernaud, Dimitris Athineos, Sandeep Dhayade et al. · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
Design, Synthesis, and Evaluation of Antifibrotic Activity of Nonsteroidal VDR Agonists Featuring 1,6-Naphthol as a CD-Ring Surrogate
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Tianzhen Wang, Liyun Duan, Beiying Zhao, Jingbin Zhang, Yongjiang Yu, Jin-Yue Zhao · 2025 · Frontiers in Immunology
Bile acids as gatekeepers: Orchestrating gut-liver axis for metabolic and immune balance
Qiang Chen, Xin LIU, Zi-Hao Jiang · 2026 · Hepatobiliary & pancreatic diseases international
Gemcitabine and nab-paclitaxel with or without the VDR agonist paricalcitol for metastatic pancreatic cancer: a randomized, multiarm, run-in phase trial
Kimberly J. Perez, Andressa Dias Costa, Alexander Jordan, Thomas Benjamin Karasic, Dalia Elganainy, Suryun Kim, Chen Yuan, Dan Y. Gui, Runzi Tan, Sung Chul Hong et al. · 2026 · Nature Cancer
Granulocyte-macrophage colony-stimulating factor (GM-CSF) shows therapeutic effect on dimethylnitrosamine (DMN)-induced liver fibrosis in rats
Mrigendra Bir Karmacharya, Binika Hada, So Ra Park, Kil Hwan Kim, Byung Hyune Choi · 2022 · PLoS ONE
Genomically anchored vitamin D receptor mediates an abundance of bioprotective actions elicited by its 1,25-dihydroxyvitamin D hormonal ligand
Mark R. Haussler, Carol A. Haussler, Peter W. Jurutka · 2023 · Vitamins and hormones
Hepatic connective tissue growth factor expression and regulation differ between non-steatotic and non-alcoholic steatotic livers from brain-dead donor
Dongjing Yang, Jihua Shi, Zongping Xia, Wen-Zhi Guo, Mohammed Shakil Ahmed, Shuijun Zhang · 2021 · Scientific Reports
The role of Vitamin D3 in ocular fibrosis and its therapeutic potential for the glaucomatous trabecular meshwork
Alexander Morelli-Batters, Hannah C. Lamont, Mirna Elghobashy, Imran Masood, Lisa J. Hill · 2022 · Frontiers in Ophthalmology
Diagnosis, Management, and Prognosis of Cystic Fibrosis-Related Liver Disease in Children
Dana-Teodora Anton-Păduraru, Alice Nicoleta Azoicai, Felicia Trofin, Alina Mariela Murgu, Dana Elena Mîndru, Ana Simona Bocec, Codruța-Olimpiada Halițchi-Iliescu, Gabriela Rusu Zota, Diana Păduraru, Eduard Vasile Năstase · 2024 · Diagnostics
Proteomic analysis of serum samples of paracoccidioidomycosis patients with severe pulmonary sequel
Amanda Ribeiro dos Santos, Aline Salgado Dionizio, Mileni da Silva Fernandes, Marília Afonso Rabelo Buzalaf, Beatriz Aparecida Soares Pereira, Débora de Fátima Almeida Donanzam, Sérgio Marrone Ribeiro, Anamaria Mello Miranda Paniago, Ricardo de Souza Cavalcante, Rinaldo Pôncio Mendes et al. · 2021 · PLoS neglected tropical diseases
Andrographolide derivative as antagonist of vitamin D receptor to induce lipidation of microtubule associate protein 1 light chain 3 (LC3)
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Effects of Hypocalcemic Vitamin D Analogs in the Expression of DNA Damage Induced in Minilungs from hESCs: Implications for Lung Fibrosis
E. Magro-López, Irene Chamorro-Herrero, Alberto Zambrano · 2021 · International Journal of Molecular Sciences
Activated Fibroblast Program Orchestrates Tumor Initiation and Progression; Molecular Mechanisms and the Associated Therapeutic Strategies
Go J Yoshida, Arata Azuma, Yukiko Miura, Akira Orimo · 2020 · Vide Leaf, Hyderabad eBooks
Role of alarmin cytokines and microRNAs in the host-schistosome interaction
Xing He, Weiqing Pan · 2018 · F1000Research
Alcoholic liver disease and vitamin D deficiency
Gianni Testino, Silvia Leone, Sharmila Fagoonee · 2018 · Minerva Medica
Calcipotriol abrogates TGF-β1/pSmad3-mediated collagen 1 synthesis in pancreatic stellate cells by downregulating RUNX1
Meifang Zheng, Hongyan Li, Li Sun, Shiyuan Cui, Wei Zhang, Yanhang Gao, Runping Gao · 2024 · Toxicology and Applied Pharmacology
Precision Targeting of Hepatic Stellate Cells: Nanotherapeutic Strategies for Liver Fibrosis Regression
Xinying Ma, Dawei Chen, Ming Zhao, Haiyang Hu · 2026 · Wiley Interdisciplinary Reviews Nanomedicine and Nanobiotechnology
Hepatocellular carcinoma and vitamin D metabolism: novel targets and therapeutic strategies
Hanlin Gao, Li He, Zhi Chen, Gang Wang · 2026 · Cellular Oncology
Heterogeneity in Pancreatitis
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Associations of vitamin D-related single nucleotide polymorphisms with post-stroke depression among ischemic stroke population
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Identification and Characterization of a Novel Nanobody Against Human CTGF to Reveal Its Antifibrotic Effect in an in vitro Model of Liver Fibrosis
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Serum 25-hydroxyvitamin D levels and risk of overall and site-specific cancers in Korean adults: results from two prospective cohort studies
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Vitamin D and Renal Disease
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Effect of the combination between empagliflozin and calcipotriol on cadmium-induced testicular toxicity in rats
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A-kinase anchoring protein 13 interacts with the vitamin D receptor to alter vitamin D-dependent gene activation in uterine leiomyoma cells
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Analysis of key genes and related transcription factors in liver fibrosis based on bioinformatic technology.
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