Acetate is a bioenergetic substrate for human glioblastoma and brain metastases

Mashimo, Tomoyuki, Pichumani, Kumar, Vemireddy, Vamsidhara, Hatanpaa, Kimmo J., Singh, Dinesh Kumar, Sirasanagandla, Shyam, Nannepaga, Suraj, Piccirillo, Sara G. +9 more·2014·Cell

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Items 301–400 of 763

  1. Cancer metabolism as a central driving force of glioma pathogenesis
    Kenta Masui, Webster K. Cavenee, Paul S. Mischel · 2016 · Brain Tumor Pathology
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