COLD1 Confers Chilling Tolerance in Rice
Open accessAbstract
Rice is sensitive to cold and can be grown only in certain climate zones. Human selection of japonica rice has extended its growth zone to regions with lower temperature, while the molecular basis of this adaptation remains unknown. Here, we identify the quantitative trait locus COLD1 that confers chilling tolerance in japonica rice. Overexpression of COLD1(jap) significantly enhances chilling tolerance, whereas rice lines with deficiency or downregulation of COLD1(jap) are sensitive to cold. COLD1 encodes a regulator of G-protein signaling that localizes on plasma membrane and endoplasmic reticulum (ER). It interacts with the G-protein α subunit to activate the Ca(2+) channel for sensing low temperature and to accelerate G-protein GTPase activity. We further identify that a SNP in COLD1, SNP2, originated from Chinese Oryza rufipogon, is responsible for the ability of COLD(jap/ind) to confer chilling tolerance, supporting the importance of COLD1 in plant adaptation.
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Pyramiding multiple genes involved in salt stress responses is important to improve crop salt tolerance.
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- Authors
- Ma, Y., Dai, X., Xu, Y., Luo, W., Zheng, X., Zeng, D., Pan, Y., Lin, X., Liu, H., Zhang, D., Xiao, J., Guo, X., Xu, S., Niu, Y., Jin, J., Zhang, H., Xu, X., Li, L., Wang, W., Qian, Q., Ge, S., & Chong, K.
- Affiliations
- Chinese Academy of Sciences (CN)
- Chinese Academy of Agricultural Sciences (CN)
- Capital Normal University (CN)
- Kunming Institute of Zoology (CN)
- Corresponding author
- Chong, Kang
- ORCID
- Venue
- Cell
- Publisher
- Elsevier BV
- Published
- 2015-03
- Volume
- 160
- Issue
- 6
- Pages
- 1209-1221
- ISSN
- 0092-8674 (ISSN-L)
- OpenAlex
- W2149875871
- Cited by
- 1,048
- References
- 71
- Citations by year
- 2026: 106 · 2025: 137 · 2024: 132 · 2023: 119 · 2022: 126 · 2021: 129 · 2020: 96 · 2019: 53 · 2018: 66 · 2017: 35 · 2016: 37 · 2015: 12
- FWCI
- 60.39
- Type
- journal article
- Language
- en
- Update notices
- erratum (2015-07-02)
- Open access
- bronze
- doi.org
- Licence
- Locations
- Cell (publishedVersion)
- PubMed (publishedVersion)
- Institute of Botany, CAS Institutional Repository (submittedVersion)
- Topics
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Plant Stress Responses and Tolerance
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Rice Cultivation and Yield Improvement
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Plant Molecular Biology Research
- Keywords
- chilling tolerance, rice, Oryza sativa subsp. japonica, quantitative trait loci, G protein signaling, G protein alpha subunit, calcium channels, GTPase activity, endoplasmic reticulum, plasma membrane, Oryza rufipogon, cold adaptation
- MeSH terms
- Amino Acid Sequence, Breeding, Cold Temperature, Endoplasmic Reticulum, Molecular Sequence Data, Mutation, Plant Proteins, Oryza, Sequence Alignment, Gene Expression Regulation, Plant, GTP-Binding Proteins, Polymorphism, Single Nucleotide, Plants, Genetically Modified, Quantitative Trait Loci, Cold Shock Proteins and Peptides
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