NF-κB c-Rel Is Crucial for the Regulatory T Cell Immune Checkpoint in Cancer

Grinberg-Bleyer, Yenkel, Oh, Hyunju, Desrichard, Alexis, Bhatt, Dev M., Caron, Rachel, Chan, Timothy A., Schmid, Roland M., Klein, Ulf +2 more·2017·Cell

DOI 10.1016/j.cell.2017.08.004

Cited by (297)

Items 101–200 of 297

Revisiting of TAMs in tumor immune microenvironment: Insight from NF-κB signaling pathway
Rui He, Yan He, Ran Du, Chenxin Liu, Zeran Chen, Anqi Zeng, Linjiang Song · 2023 · Biomedicine & Pharmacotherapy
The NF-κB signaling network in the life of T cells
M. Daniels, E. Teixeiro · 2025 · Frontiers in Immunology
Phenotypic and Functional Properties of Tumor-Infiltrating Regulatory T Cells
Gap Ryol Lee · 2017 · Mediators of Inflammation
Regulating the regulatory T cells as cell therapies in autoimmunity and cancer
Hamed Hosseinalizadeh, Fatemeh Rabiee, Negar Eghbalifard, Hamid Rajabi, Daniel J. Klionsky, Aryan Rezaee · 2023 · Frontiers in Medicine
The ratio of CD8 + lymphocytes to tumor-infiltrating suppressive FOXP3 + effector regulatory T cells is associated with treatment response in invasive breast cancer
Noriko Goda, Shinsuke Sasada, Hideo Shigematsu, Norio Masumoto, Koji Arihiro, Hiroyoshi Nishikawa, Shimon Sakaguchi, Morihito Okada, Takayuki Kadoya · 2022 · Discover Oncology
Immunometabolism of regulatory T cells in cancer
Jordy Saravia, Hongbo Chi · 2025 · Oncogene
MicroRNA-365a-3p inhibits c-Rel-mediated NF-κB signaling and the progression of pancreatic cancer
Libo Yin, Xi Xiao, Christina Georgikou, Yefeng Yin, Li Liu, Svetlana Karakhanova, Yiqiao Luo, Jury Gladkich, Jörg Fellenberg, Carsten Sticht et al. · 2019 · Cancer Letters
Whole-genome analysis of TET dioxygenase function in regulatory T cells
Xiaojing Yue, Daniela Samaniego‐Castruita, Edahí González‐Avalos, Xiang Li, Benjamin G. Barwick, Anjana Rao · 2021 · EMBO Reports
Negative intracellular regulators of T-cell receptor (TCR) signaling as potential antitumor immunotherapy targets
Vladimir Laletin, Pierre-Louis Bernard, Cathy Costa Da Silva, Geoffrey C. Guittard, Jacques A. Nunès · 2023 · Journal for ImmunoTherapy of Cancer
The function and potential drug targets of tumour-associated Tregs for cancer immunotherapy
Shanshan Yan, Yaguang Zhang, Bing Sun · 2019 · Science China Life Sciences
Targeting Regulatory T Cells by Addressing Tumor Necrosis Factor and Its Receptors in Allogeneic Hematopoietic Cell Transplantation and Cancer
Harald Wajant, Andreas Beilhack · 2019 · Frontiers in Immunology
Mechanisms of Resistance to Checkpoint Blockade Therapy
Hubing Shi, Jiang Lan, Jiqiao Yang · 2020 · Advances in experimental medicine and biology
Epigenetic regulation of HBV-specific tumor-infiltrating T cells in HBV-related HCC
Maojun You, Yanan Gao, Junliang Fu, Runze Xie, Zhenyu Zhu, Zhixian Hong, Lingzhan Meng, Shunda Du, Junliang Liu, Fu‐Sheng Wang et al. · 2023 · Hepatology
TNFR1 and TNFR2, Which Link NF-κB Activation, Drive Lung Cancer Progression, Cell Dedifferentiation, and Metastasis
Gongping Shi, Yinling Hu · 2023 · Cancers
The Molecular Aspect of Antitumor Effects of Protease Inhibitor Nafamostat Mesylate and Its Role in Potential Clinical Applications
Xi Chen, Zhijie Xu, Shuangshuang Zeng, Xiang Wang, Wanli Liu, Long Qian, Jie Wei, Xue Yang, Qiuying Shen, Zhicheng Gong et al. · 2019 · Frontiers in Oncology
Chronic arsenic exposure induces the time-dependent modulation of inflammation and immunosuppression in spleen
Nan Yan, Guowei Xu, Chenchen Zhang, Xuping Liu, Xin Li, Lin Sun, Wang Da, Xiaoxu Duan, Bing Jhang Li · 2020 · Cell & Bioscience
c-Rel orchestrates energy-dependent epithelial and macrophage reprogramming in fibrosis
Jack Leslie, Marina García Macia, Saimir Luli, Julie C. Worrell, William J. Reilly, Hannah L. Paish, Amber Knox, Ben S. Barksby, Lucy Gee, Marco Y. W. Zaki et al. · 2020 · Nature Metabolism
Expanding the Clinical and Immunological Phenotypes and Natural History of MALT1 Deficiency
Asena Pınar Sefer, Hassan Abolhassani, Franziska Ober, Başak Kayaoğlu, Sevgi Bilgiç Eltan, Altan Kara, Baran Erman, Naz Surucu Yilmaz, Çiğdem Aydoğmuş, Sezin Aydemir et al. · 2022 · Journal of Clinical Immunology
Calcitriol and Its Analogs Establish the Immunosuppressive Microenvironment That Drives Metastasis in 4T1 Mouse Mammary Gland Cancer
Agata Pawlik, Artur Anisiewicz, Beata Filip‐Psurska, Marcin Nowak, Eliza Turlej, Justyna Trynda, Joanna Banach, Paweł Gretkierewicz, Joanna Wietrzyk · 2018 · International Journal of Molecular Sciences
Inhibition of Glycolysis in Pathogenic TH17 Cells through Targeting a miR-21–Peli1–c-Rel Pathway Prevents Autoimmunity
Rong Qiu, Xiang Yu, Li Wang, Zhijun Han, Chao Yao, Yange Cui, Guojun Hou, Dai Dai, Wenfei Jin, Nan Shen · 2020 · The Journal of Immunology
Different subpopulations of regulatory T cells in human autoimmune disease, transplantation, and tumor immunity
Zhongyi Jiang, Haitao Zhu, Pusen Wang, Weitao Que, Lin Zhong, Xiao‐Kang Li, Futian Du · 2022 · MedComm
Combining precision oncology and immunotherapy by targeting the MALT1 protease
Thorsten R. Mempel, Daniel Krappmann · 2022 · Journal for ImmunoTherapy of Cancer
Current state of immune checkpoints therapy for glioblastoma
He Wang, Jing Yang, Xiangjun Li, Zhao Hai · 2024 · Heliyon
NF-κB signaling and the tumor microenvironment in osteosarcoma: implications for immune evasion and therapeutic resistance
Shaoyan Shi, Xuehai Ou, Chao Liu, Rui Li, Qianjin Zheng, Leiming Hu · 2025 · Frontiers in Immunology
Diversity of intratumoral regulatory T cells in B-cell non-Hodgkin lymphoma
Ivana Spasevska, Ankush Sharma, Chloé Beate Steen, Sarah E. Josefsson, Yngvild Nuvin Blaker, Arne Kolstad, Even Holth Rustad, Saskia Meyer, Kathrine T. Isaksen, Stalin Chellappa et al. · 2023 · Blood Advances
Tumor immune microenvironment and the current immunotherapy of cholangiocarcinoma (Review)
Siqi Yang, Rui-Qi Zou, Yu-Shi Dai, Ya-Fei Hu, Fu‐Yu Li, Hai‐Jie Hu · 2023 · International Journal of Oncology
Transcriptional regulation of Treg homeostasis and functional specification
Ke Wang, Wenxian Fu · 2020 · Cellular and Molecular Life Sciences
Noc4L-Mediated Ribosome Biogenesis Controls Activation of Regulatory and Conventional T Cells
Xueping Zhu, Wei Zhang, Jie Guo, Xuejie Zhang, Liping Li, Ting Wang, Jinghua Yan, Fuping Zhang, Baidong Hou, Ning Gao et al. · 2019 · Cell Reports
The Hippo Signaling Pathway: The Trader of Tumor Microenvironment
Duo Yang, Na Zhang, Meihua Li, Tao Hong, Wei Meng, Taohui Ouyang · 2021 · Frontiers in Oncology
Programmable Bispecific Nano-immunoengager That Captures T Cells and Reprograms Tumor Microenvironment
Lu Zhang, Ruonan Bo, Yi Wu, Longmeng Li, Zheng Gang Zhu, Ai‐Hong Ma, Wenwu Xiao, Yanyu Huang, Tatu Rojalin, Xingbin Yin et al. · 2022 · Nano Letters
Regulatory T cells promote adipocyte beiging in subcutaneous adipose tissue
Wenqian Fang, Zhiyong Deng, Feriel Benadjaoud, Dafeng Yang, Chongzhe Yang, Guo‐Ping Shi · 2020 · The FASEB Journal
Single-Cell Sequencing Reveals the Transcriptome and TCR Characteristics of pTregs and in vitro Expanded iTregs
Zhenzhen Hui, Jiali Zhang, Yu Zheng, Lili Yang, Wenwen Yu, Yang An, Feng Wei, Xiubao Ren · 2021 · Frontiers in Immunology
Regulatory T-Cells and Multiple Myeloma: Implications in Tumor Immune Biology and Treatment
Christina Hadjiaggelidou, Eirini Katodritou · 2021 · Journal of Clinical Medicine
The mechanisms on evasion of anti-tumor immune responses in gastric cancer
Junyang Wang, Tong Liu, Tao Huang, Mei Shang, Xudong Wang · 2022 · Frontiers in Oncology
Proteomic Analysis Reveals Inflammation Modulation of κ/ι-Carrageenan Hexaoses in Lipopolysaccharide-Induced RAW264.7 Macrophages
Juanjuan Guo, Jinghao Chen, Xu Lu, Zebin Guo, Zhiwei Huang, Shaoxiao Zeng, Yi Zhang, Baodong Zheng · 2018 · Journal of Agricultural and Food Chemistry
Mitochondria-specific gadolinium (III) porphyrinate as efficient ROS generator for MRI visualization and sonodynamic-immunotherapy of deep localized tumors
Xipeng Li, Qin Zeng, Ruijing Zhang, Jiajun Li, Da Xing, Tao Zhang · 2022 · Chemical Engineering Journal
Targeting NF-κB Signaling in Cancer Stem Cells: A Narrative Review
Barbara Kaltschmidt, Kaya E. Witte, Johannes F. W. Greiner, Florian Weißinger, Christian Kaltschmidt · 2022 · Biomedicines
Significance of regulatory T cells in cancer immunology and immunotherapy
Daisuke Sugiyama, Kunihiko Hinohara, Hiroyoshi Nishikawa · 2022 · Experimental Dermatology
Decidual RANKL/RANK interaction promotes the residence and polarization of TGF-β1-producing regulatory γδ T cells
Ruiqi Chang, Jun Shao, Yuhan Meng, Jian Wang, Da‐Jin Li, Ming-Qing Li · 2019 · Cell Death and Disease
NF-κB c-Rel is a critical regulator of TLR7-induced inflammation in psoriasis
Angela Rose Liu, Nandini Sarkar, Jordan D. Cress, Tristan J de Jesus, Ananya Vadlakonda, Joshua T Centore, Alexis D. Griffith, Bethany R. Rohr, Thomas S. McCormick, Kevin D. Cooper et al. · 2024 · EBioMedicine
Tumor Tolerance–Promoting Function of Regulatory T Cells Is Optimized by CD28, but Strictly Dependent on Calcineurin
Francesco Marangoni, Ruan Zhang, Vinidhra Mani, Martin Thelen, Noor J Ali Akbar, Ross D. Warner, Tarmo Äijö, Valentina Zappulli, Gustavo Martínez, Laurence A. Turka et al. · 2018 · The Journal of Immunology
Negative regulation of FOXP3 expression by c-Rel O-GlcNAcylation
Tristan J de Jesus, Jeffrey Alan Tomalka, Joshua T Centore, Franklin D. Staback Rodriguez, Ruchira A Agarwal, Angela R Liu, Timothy S. Kern, Parameswaran Ramakrishnan · 2021 · Glycobiology
NF-κB Mutations in Germinal Center B-Cell Lymphomas: Relation to NF-κB Function in Normal B Cells
Laura Pasqualucci, Ulf Klein · 2022 · Biomedicines
Role of the NF-κB Family Member RelB in Regulation of Foxp3+ Regulatory T Cells In Vivo
Junhui Li, Shuqiu Chen, Wenhao Chen, Qifa Ye, Yaling Dou, Yue Xiao, Lei Zhang, Laurie J. Minze, X.C. Li, Xiang Xiao · 2018 · The Journal of Immunology
Tumor Necrosis Factor Receptor Superfamily in T Cell Priming and Effector Function
James Muller, Audrey Baeyens, Michael Loran Dustin · 2018 · Advances in immunology
Pan-Cancer Analysis of the Characteristics of LY96 in Prognosis and Immunotherapy Across Human Cancer
Kechao Nie, Jing Li, Luqi Peng, Mei Zhang, Wei Huang · 2022 · Frontiers in Molecular Biosciences
The Unsolved Puzzle of c-Rel in B Cell Lymphoma
Maike Kober, Marc Schmidt‐Supprian · 2019 · Cancers
A Pan-Cancer Analysis Reveals the Prognostic and Immunotherapeutic Value of Stanniocalcin-2 (STC2)
Zhong-Hui Jiang, Xianfeng Shen, Yanhong Wei, Yongji Chen, Hongbo Chai, Lingyun Xia, Wei‐Dong Leng · 2022 · Frontiers in Genetics
Local T regulatory cells depletion by an integrated nanodrug system for efficient chem-immunotherapy of tumor
Fan Gao, Cheng Qian, Miao‐Deng Liu, Lei Rong, Chuan‐Jun Liu, Xian‐Zheng Zhang · 2019 · Science China Chemistry
Analysis of Circular RNA-Related Competing Endogenous RNA Identifies the Immune-Related Risk Signature for Colorectal Cancer
Wei Song, Jun Ren, Chuntao Wang, Yuhang Ge, Tao Fu · 2020 · Frontiers in Genetics
The NF-κB Transcription Factor c-Rel Modulates Group 2 Innate Lymphoid Cell Effector Functions and Drives Allergic Airway Inflammation
Barbara C. Mindt, Sai Sakktee Krisna, Claudia U. Duerr, Mathieu Mancini, Lara Richer, Silvia Marina Vidal, Steve Gerondakis, David Langlais, Jörg Hermann Fritz · 2021 · Frontiers in Immunology
NF-κB subunits RelA and c-Rel selectively control CD4+ T cell function in multiple sclerosis and cancer
Guilhem Lalle, Raphaëlle Lautraite, Khaled Bouherrou, Maud Plaschka, Aurora Pignata, Allison Voisin, Julie Twardowski, Marlène Perrin-Niquet, Pierre Stéphan, Sarah Durget et al. · 2024 · The Journal of Experimental Medicine
IKKα-deficient lung adenocarcinomas generate an immunosuppressive microenvironment by overproducing Treg-inducing cytokines
Na‐Young Song, Xin Li, Buyong Ma, Jami Willette‐Brown, Feng Zhu, Chengfei Jiang, Ling Su, Jyoti Shetty, Yongmei Zhao, Gongping Shi et al. · 2022 · Proceedings of the National Academy of Sciences
The many-sided contributions of NF-κB to T-cell biology in health and disease
Allison Voisin, Yenkel Grinberg‐Bleyer · 2020 · International review of cytology
Dihydroartemisinin Beneficially Regulates Splenic Immune Cell Heterogeneity Through the SOD3-JNK-AP-1 Axis
Yiwei Zhang, Qilong Li, Ning Jiang, Ziwei Su, Quan Yuan, Lei Lv, Xiaoyu Sang, Ran Chen, Ying Feng, Qijun Chen · 2021 · Science China Life Sciences
FOXP3 and Its Cofactors as Targets of Immunotherapies
Yasuhiro Nagai, Lian Lam, Mark Irwin Greene, Hongtao Zhang · 2019 · Engineering
Role of NF-kappaB2-p100 in regulatory T cell homeostasis and activation
Atika Dhar, Meenakshi Chawla, Somdeb Chattopadhyay, Neelam Oswal, Danish Umar, Suman Gupta, Vineeta Bal, Satyajit Rath, Anna George, Gopalakrishnan Aneeshkumar Arimbasseri et al. · 2019 · Scientific Reports
Attenuation of canonical NF‐κB signaling maintains function and stability of human Treg
Liesa S. Ziegler, Marlene C. Gerner, Ralf L. J. Schmidt, Doris Trapin, Peter Steinberger, Winfried Franz Pickl, Christian Sillaber, Gerda Egger, Ilse Schwarzinger, Klaus G. Schmetterer · 2020 · FEBS Journal
Blocking LTB4 signaling-mediated TAMs recruitment by Rhizoma Coptidis sensitizes lung cancer to immunotherapy
Jiangna Yan, Jinglin Zhu, Xiaolan Li, Ruijie Yang, Wei Xiao, Chao Huang, Chunli Zheng · 2023 · Phytomedicine
Epigenetic reprogramming of T cells: unlocking new avenues for cancer immunotherapy
Vipin Singh, Sandhik Nandi, Aritra Ghosh, Santanu Adhikary, Shravanti Mukherjee, Siddhartha Roy, Chandrima Das · 2024 · Cancer and Metastasis Reviews
p50 suppresses cytotoxic T lymphocyte effector function to regulate tumor immune escape and response to immunotherapy
Chunwan Lu, John David Klement, Alyssa D. Smith, Dafeng Yang, Jennifer L. Waller, Darren D. Browning, David H. Munn, Kebin Liu · 2020 · Journal for ImmunoTherapy of Cancer
Iron oxide-based enzyme mimic nanocomposite for dual-modality imaging guided chemical phototherapy and anti-tumor immunity against immune cold triple-negative breast cancer
Xiuhong Guan, Jiesong Li, Jiali Cai, Shihui Huang, Hong Liu, Sheng Wang, Xiaoyong Zhang, Yi Sun, Hongyan Liu, Guoxi Xie et al. · 2021 · Chemical Engineering Journal
Glut3 promotes cellular O-GlcNAcylation as a distinctive tumor-supportive feature in Treg cells
Amit Sharma, Garima Sharma, Zhen Gao, Ke Li, Ming‐Qing Li, Menglin Wu, Chan Johng Kim, Yingjia Chen, Anupam Gautam, Hong Bae Choi et al. · 2024 · Cellular and Molecular Immunology
Post-translational governance of NF-κB in cancer immunity: mechanisms and therapeutic horizons
Yue Hong, Ying Fu, Qian Long · 2025 · Frontiers in Immunology
Comprehensive Genetic Profiling Reveals Frequent Alterations of Driver Genes on the X Chromosome in Extranodal NK/T-cell Lymphoma
Yuta Ito, Amira Marouf, Yasunori Kogure, Junji Koya, Raphaël Liévin, Julie Bruneau, Mariko Tabata, Yuki Saito, Sumito Shingaki, Mitsuhiro Yuasa et al. · 2024 · Cancer Research
A Matter of Choice: Inhibition of c-Rel Shifts Neuronal to Oligodendroglial Fate in Human Stem Cells
Lucia Mercedes Ruiz-Perera, Johannes F. W. Greiner, Christian Kaltschmidt, Barbara Kaltschmidt · 2020 · Cells
Yolk sac-derived Pdcd11-positive cells modulate zebrafish microglia differentiation through the NF-κB-Tgfβ1 pathway
Ruimeng Yang, Ming Zhan, Miaomiao Guo, Hao Yuan, Yiqin Wang, Yiyue Zhang, Wenqing Zhang, Saijuan Chen, Hugues de Thé, Chen Hui Zhu et al. · 2020 · Cell Death and Differentiation
Differentiation and homeostasis of effector Treg cells are regulated by inositol polyphosphates modulating Ca <sup>2+</sup> influx
Min, Hyungyu, Kim, Wooseob, Hong, Sehoon, Lee, Sungkyu, Jeong, Jinguk, Kim, Seyun, Seong, Rho H. · 2022 · Proceedings of the National Academy of Sciences
NFκB1 inhibits memory formation and supports effector function of ILC2s in memory-driven asthma
Mukesh Verma, Divya Verma, Anand Sripada, Kapil Sirohi, Rangati Varma, Anita Sahu, Rafeul Alam · 2023 · Frontiers in Immunology
T Cells Instruct Immune Checkpoint Inhibitor Therapy Resistance in Tumors Responsive to IL1 and TNFα Inflammation
Nam Woo Cho, Sophia M. Guldberg, Barzin Y. Nabet, Jie Zeng, Eun Ji Kim, Kamir J. Hiam-Galvez, Jacqueline L. Yee, Rachel DeBarge, Iliana Tenvooren, Naa Asheley Ashitey et al. · 2024 · Cancer Immunology Research
Coley’s Toxin to First Approved Therapeutic Vaccine—A Brief Historical Account in the Progression of Immunobiology-Based Cancer Treatment
K. Devaraja, Manisha Singh, Krishna Sharan, Sadhna Aggarwal · 2024 · Biomedicines
NF-κB c-Rel Is Dispensable for the Development but Is Required for the Cytotoxic Function of NK Cells
Yorleny M. Vicioso, Derek P. Wong, Nand Kishor Roy, Nayanika Das, Keman Zhang, Parameswaran Ramakrishnan, Reshmi Parameswaran · 2021 · Frontiers in Immunology
Genetic engineering of T cells with chimeric antigen receptors for hematological malignancy immunotherapy
Dongdong Ti, Yunfei Niu, Zhiqiang Wu, Xiaobing Fu, Weidong Han · 2018 · Science China Life Sciences
Distinct immunophenotypic profiles and neutrophil heterogeneity in colorectal cancer
Minghua Bai, Yuzhao Jin, Zihao Jin, Yuhao Xie, Jinggang Chen, Qingping Zhong, Zhen‐Bo Wang, Qian Zhang, Yanmei Cai, FangYa Qun et al. · 2025 · Cancer Letters
Knockdown of LAP2α inhibits osteogenic differentiation of human adipose-derived stem cells by activating NF-κB
Yiman Tang, Xiao Zhang, Wenshu Ge, Yongsheng Zhou · 2020 · Stem Cell Research & Therapy
Targeting regulatory T cells
Sarah Crunkhorn · 2017 · Nature Reviews Drug Discovery
ZSCAN16 promotes proliferation, migration and invasion of bladder cancer via regulating NF-kB, AKT, mTOR, P38 and other genes
Xuanhao Li, Donghao Shang, Hongliang Shen, Jian Song, Gangyue Hao, Ye Tian · 2020 · Biomedicine & Pharmacotherapy
MALT1 protease function in regulatory T cells induces MYC activity to promote mitochondrial function and cellular expansion
Marc Rosenbaum, Theresa Schnalzger, Thomas Engleitner, Christin Weiß, Ritu Mishra, Cora Mibus, Theresa Mitterer, Roland Rad, Jürgen Ruland · 2021 · European Journal of Immunology
Identification and Validation of 17-lncRNA Related to Regulatory T Cell Heterogeneity as a Prognostic Signature for Head and Neck Squamous Cell Carcinoma
Qi Sun, Yumei Li, Xin Ling Yang, Xinxin Wu, Zhen Liu, Yakui Mou, Xicheng Song · 2021 · Frontiers in Immunology
scSTAR reveals hidden heterogeneity with a real-virtual cell pair structure across conditions in single-cell RNA sequencing data
Jie Hao, Jiawei Zou, Jiaqiang Zhang, Ke Chen, Duojiao Wu, Wei Cao, Guoguo Shang, Jean Yee Hwa Yang, KongFatt Wong‐Lin, Hourong Sun et al. · 2023 · Briefings in Bioinformatics
Translational Studies Using the MALT1 Inhibitor ( S )-Mepazine to Induce Treg Fragility and Potentiate Immune Checkpoint Therapy in Cancer
Mauro Di Pilato, Yun Gao, Yi Sun, Amina Fu, Carina Graß, Thomas Seeholzer, Regina Feederle, Irina B. Mazo, Samuel W. Kazer, Kevin Litchfield et al. · 2023 · Journal of Immunotherapy and Precision Oncology
FOXP3 and Tip60 Structural Interactions Relevant to IPEX Development Lead to Potential Therapeutics to Increase FOXP3 Dependent Suppressor T Cell Functions
Payal Grover, Peeyush N. Goel, Ciriaco A. Piccirillo, Mark Irwin Greene · 2021 · Frontiers in Pediatrics
Nanomaterials-involved strategies for reversing the immunosuppressive factors and improving antitumor immunotherapy
Fan Gao, JianHui Dong, Chun Xue, Lei An, Tian Zhang, Wen-Jun Wang, Changjin Ou, Xiaochen Dong · 2023 · Nano Today
TuBG1 promotes hepatocellular carcinoma via ATR/P53-apoptosis and cycling pathways
Yan Zhang, Zhenzhen Wang, An-Qi Han, Ming-Ya Yang, Lixin Zhu, Fa-Ming Pan, Yong Wang · 2023 · Hepatobiliary & pancreatic diseases international
Challenges and unanswered questions for the next decade of immune-oncology research in NSCLC
Niki Karachaliou, Manuel Fernández-Bruno, Jillian Wilhelmina Paulina Bracht, Rafael Rosell · 2018 · Translational Lung Cancer Research
Targeting NF-κB c-Rel in regulatory T cells to treat corneal transplantation rejection
Jiang Bian, Ting Wang, Jijun Sun, Xiaozhen He, Zhijiao Wu, Songmei Zhang, Hao Chi, Tingting Fan, Shaowen Wang, Weiyun Shi et al. · 2021 · American Journal of Transplantation
Immunoinhibitory effects of hypoxia-driven reprogramming of EGR1hi and EGR3 positive B cells in the nasopharyngeal carcinoma microenvironment
Yizhi Ge, Haitao Liu, Wenxuan Huang, Huanfeng Zhu, Dan Zong, Xia He · 2024 · Oral Oncology
Balancing Tumor Immunotherapy and Immune-Related Adverse Events: Unveiling the Key Regulators
Jianshang Huang, Lei Xiong, Sainan Tang, Junhao Zhao, Li Zuo · 2024 · International Journal of Molecular Sciences
NF‐ κ B‐Related Metabolic Gene Signature Predicts the Prognosis and Immunotherapy Response in Gastric Cancer
Qiuxiang Chen, Xiaojing Du, Sunkuan Hu, Qingke Huang · 2022 · BioMed Research International
Inflammatory cytokine‐enriched microenvironment plays key roles in the development of breast cancers
Yasuto Takeuchi, Noriko Gotoh · 2023 · Cancer Science
Critical Roles of Balanced T Helper 9 Cells and Regulatory T Cells in Allergic Airway Inflammation and Tumor Immunity
Muhua Huang, Jingcheng Dong · 2021 · Journal of Immunology Research
Locoregional therapies combined with immune checkpoint inhibitors for liver metastases
Xingchen Zhang, Yuwen Zhou, Gui-Xia Wei, Yiqiao Luo, Meng Qiu · 2024 · Cancer Cell International
Non-canonical PRC1.1 licenses transcriptional response to enable Treg plasticity in immune adaptation
Ting Li, Yingying Zhao, Qian Li, Zhaoran Sun, Ni Wang, Liangyu Xing, Nan Tang, Runyuan Mao, Yuxin Wang, Jiacheng Su et al. · 2025 · Molecular Cell
Systematic profiling of immune signatures identifies prognostic predictors in lung adenocarcinoma
Shuangshuang Mao, Yuan Li, Zhiliang Lu, Yun Che, Jianbing Huang, Yuanyuan Lei, Yalong Wang, Xin‐Feng Wang, Chengming Liu, Sufei Zheng et al. · 2020 · Cellular Oncology
Th2 polarization in target organs is involved in the alleviation of pathological damage mediated by transplanting granulocyte colony-stimulating factor-primed donor T cells
Yang Zhou, Leqing Cao, Huidong Guo, Yan Hong, Ming Wang, Ke Wang, Xiao‐Jun Huang, Ying‐Jun Chang · 2020 · Science China Life Sciences
Bcl‐3 suppresses differentiation of RORγt+ regulatory T cells
Wanhu Tang, Sun Saret, Ruxiao Tian, Hongshan Wang, Estefanı́a Claudio, Philip M. Murphy, Ulrich K. Siebenlist · 2021 · Immunology and Cell Biology
TRAF6 controls T cell homeostasis by maintaining the equilibrium of MALT1 scaffolding and protease functions
Thomas J. O’Neill, Andreas Gewies, Thomas Seeholzer, Daniel Krappmann · 2023 · Frontiers in Immunology
NFKB2 mediates colorectal cancer cell immune escape and metastasis in a STAT2/PD‐L1‐dependent manner
Jiwei Zhang, Fen Ma, Zhe Li, Yuan Li, Xun Sun, Mingxu Song, Fan Yang, Enjiang Wu, Xiaohui Wei, Zhengtao Wang et al. · 2024 · MedComm
The Role of Nuclear Factor-κB in Cancer Immunity and Immunoediting
Sumon Mukherjee, Subhadip Pati, Subhanki Dhar, Tania Sarkar, Silpita Paul, Udit Basak, Sourio Chakraborty, Gaurisankar Sa · 2025 · Cancer Control
NF-κB1 Regulates Immune Environment and Outcome of Notch-Dependent T-Cell Acute Lymphoblastic Leukemia
Paola Grazioli, Andrea Orlando, Nike Giordano, Claudia Noce, Giovanna Peruzzi, Gaia Scafetta, Isabella Screpanti, Antonio Francesco Campese · 2020 · Frontiers in Immunology