Human ADAR1 Prevents Endogenous RNA from Triggering Translational Shutdown

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Items 401–500 of 529

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  12. ADAR1 loss-of-function variants altering RNA editing define a new interferon-dependent psoriasis subtype
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  15. Overexpression of Egr1 Transcription Regulator Contributes to Schwann Cell Differentiation Defects in Neural Crest-Specific Adar1 Knockout Mice
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  24. Hippocampal adenosine-to-inosine RNA editing in sepsis: dynamic changes and influencing factors
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  26. RNA: An Introduction
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  28. A hepatitis B virus RNA-sensing and RNA-editing-dependent reporter system
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  29. Cromolyn as a novel pharmacophore of the Zα domain of the RNA ‐editing enzyme ADAR1p150
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  30. SARS-CoV-2 Infection-Induced Alterations in ADAR Editing Patterns Differ Between Patients Who Developed Critical Compared to Non-Critical COVID-19
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  31. A dynamic RNA editing landscape in porcine spleen highlights a post-transcriptional mechanism for immune maturation
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  32. Depletion of the RNA‐Editing Enzyme ADAR1 Invigorates the Antitumor Immunity of NK Cells
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  36. ADAR1 Controls Macrophage Scavenging and Lipid‐Buffering Programs in Metabolic Tissues
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  37. Targeting ADAR1 lactylation activates innate immune and overcomes chemoresistance in ovarian cancer
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  40. Viral mimicry escape as a necessary feature of malignant transformation
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  41. ZBP1 specifically binds pre-formed Z-RNA, limiting its potential pool of nucleic acid ligands compared to ADAR1
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  42. Interfering with interferon by RNA editing
    Eytan Zlotorynski · 2018 · Nature Reviews Molecular Cell Biology
  43. Generation of three induced pluripotent stem cell lines from individuals with Aicardi-Goutières syndrome caused by a c.3019G>A (p.G1007R) autosomal dominant pathogenic variant in ADAR1
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  44. Loss of ADAR1 protein induces changes in small RNA landscape in hepatocytes
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  45. Epitranscriptome-wide profiling identifies RNA editing events regulated by ADAR1 that are associated with DNA repair mechanisms in human TK6 cells
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  49. 3’ untranslated regions of Marburg and Ebola virus mRNAs possess negative regulators of translation that are modulated by ADAR1 editing
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  50. RNA-Editing-Initiated MAVS Signaling is a Key Epitranscriptomic Alteration in Human B Cell Lymphoma
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  52. ADAR1p150 RNA binding, independent of A-to-I RNA editing, buffers immunogenicity from the tonic type I IFN induced transcriptome in vivo
    Jacki E. Heraud-Farlow, Scott Taylor, Ankita Goradia, Alistair M. Chalk, Paul Francis Harrison, Zhen Liang, Monique F. M. A. Smeets, David J. Izon, Shi-Bin Hu, Jin Billy Li et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
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  62. WITHDRAWN: Changes in ADAR1 activity during Plasmodium infection contribute to protection from malaria
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  80. Additional file 2 of RNA editing in cancer impacts mRNA abundance in immune response pathways
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  81. Additional file 1 of Characterization of tumor microenvironment and tumor immunology based on the double-stranded RNA-binding protein related genes in cervical cancer
    Li, Jin, Chong Wan, Li, Xiaoqi, Quan, Chenlian, Li, Xiaoqiu, Wu, Xiaohua · 2024 · Figshare
  82. Additional file 5 of Dysregulated RNA editing of EIF2AK2 in polycystic ovary syndrome: clinical relevance and functional implications
    Kong, Fan-Sheng, Feng, Junjie, Yao, Jin-Ping, Lu, Yinghua, Guo, Tao, Sun, Meng, Ren, Chun-Yan, Jin, Yun-Yun, Ma, Yaping, Jian‐Huan Chen · 2024 · Figshare
  83. Additional file 2 of Characterization of tumor microenvironment and tumor immunology based on the double-stranded RNA-binding protein related genes in cervical cancer
    Li, Jin, Chong Wan, Li, Xiaoqi, Quan, Chenlian, Li, Xiaoqiu, Wu, Xiaohua · 2024 · Figshare
  84. Additional file 1 of Dysregulated RNA editing of EIF2AK2 in polycystic ovary syndrome: clinical relevance and functional implications
    Kong, Fan-Sheng, Feng, Junjie, Yao, Jin-Ping, Lu, Yinghua, Guo, Tao, Sun, Meng, Ren, Chun-Yan, Jin, Yun-Yun, Ma, Yaping, Jian‐Huan Chen · 2024 · Figshare
  85. Additional file 8 of Dysregulated RNA editing of EIF2AK2 in polycystic ovary syndrome: clinical relevance and functional implications
    Kong, Fan-Sheng, Feng, Junjie, Yao, Jin-Ping, Lu, Yinghua, Guo, Tao, Sun, Meng, Ren, Chun-Yan, Jin, Yun-Yun, Ma, Yaping, Jian‐Huan Chen · 2024 · Figshare
  86. Additional file 3 of RNA editing in cancer impacts mRNA abundance in immune response pathways
    Tracey W. Chan, Fu, Ting, Jae Hoon Bahn, Jun, Hyun-Ik, Lee, Jae-Hyung, Giovanni Quinones-Valdez, Cheng, Chonghui, Xinshu Grace Xiao · 2020 · Figshare
  87. Additional file 3 of Dysregulated RNA editing of EIF2AK2 in polycystic ovary syndrome: clinical relevance and functional implications
    Kong, Fan-Sheng, Feng, Junjie, Yao, Jin-Ping, Lu, Yinghua, Guo, Tao, Sun, Meng, Ren, Chun-Yan, Jin, Yun-Yun, Ma, Yaping, Jian‐Huan Chen · 2024 · Figshare
  88. Additional file 11 of Dysregulated RNA editing of EIF2AK2 in polycystic ovary syndrome: clinical relevance and functional implications
    Kong, Fan-Sheng, Feng, Junjie, Yao, Jin-Ping, Lu, Yinghua, Guo, Tao, Sun, Meng, Ren, Chun-Yan, Jin, Yun-Yun, Ma, Yaping, Jian‐Huan Chen · 2024 · Figshare
  89. Additional file 9 of Dysregulated RNA editing of EIF2AK2 in polycystic ovary syndrome: clinical relevance and functional implications
    Kong, Fan-Sheng, Feng, Junjie, Yao, Jin-Ping, Lu, Yinghua, Guo, Tao, Sun, Meng, Ren, Chun-Yan, Jin, Yun-Yun, Ma, Yaping, Jian‐Huan Chen · 2024 · Figshare
  90. Additional file 7 of Dysregulated RNA editing of EIF2AK2 in polycystic ovary syndrome: clinical relevance and functional implications
    Kong, Fan-Sheng, Feng, Junjie, Yao, Jin-Ping, Lu, Yinghua, Guo, Tao, Sun, Meng, Ren, Chun-Yan, Jin, Yun-Yun, Ma, Yaping, Jian‐Huan Chen · 2024 · Figshare
  91. Additional file 4 of Dysregulated RNA editing of EIF2AK2 in polycystic ovary syndrome: clinical relevance and functional implications
    Kong, Fan-Sheng, Feng, Junjie, Yao, Jin-Ping, Lu, Yinghua, Guo, Tao, Sun, Meng, Ren, Chun-Yan, Jin, Yun-Yun, Ma, Yaping, Jian‐Huan Chen · 2024 · Figshare
  92. Additional file 6 of Dysregulated RNA editing of EIF2AK2 in polycystic ovary syndrome: clinical relevance and functional implications
    Kong, Fan-Sheng, Feng, Junjie, Yao, Jin-Ping, Lu, Yinghua, Guo, Tao, Sun, Meng, Ren, Chun-Yan, Jin, Yun-Yun, Ma, Yaping, Jian‐Huan Chen · 2024 · Figshare
  93. Additional file 2 of Dysregulated RNA editing of EIF2AK2 in polycystic ovary syndrome: clinical relevance and functional implications
    Kong, Fan-Sheng, Feng, Junjie, Yao, Jin-Ping, Lu, Yinghua, Guo, Tao, Sun, Meng, Ren, Chun-Yan, Jin, Yun-Yun, Ma, Yaping, Jian‐Huan Chen · 2024 · Figshare
  94. Additional file 10 of Dysregulated RNA editing of EIF2AK2 in polycystic ovary syndrome: clinical relevance and functional implications
    Kong, Fan-Sheng, Feng, Junjie, Yao, Jin-Ping, Lu, Yinghua, Guo, Tao, Sun, Meng, Ren, Chun-Yan, Jin, Yun-Yun, Ma, Yaping, Jian‐Huan Chen · 2024 · Figshare
  95. ADAR1 upregulates the translation of cytochrome c via the inhibition of translocation into stress granules, facilitating apoptosis by an anticancer agent
    Motoki Isono, Tomoka Yamakawa, Kyoka Nagaoka, Masataka Nakano, Tatsuki Fukami, M NAKAJIMA · 2026 · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
  96. Mitochondrial dsRNA: A Hidden Source of Immunogenic RNA in ADAR1 Deficiency
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  97. Contrasting functions of ATP hydrolysis by MDA5 and LGP2 in viral RNA sensing
    Singh, Rahul, Wu, Yuan, Herrero del Valle, Alba, Leigh, Kendra E., Cheng, Mark T. K., Ferguson, Brian J., Modis, Yorgo · 2023
  98. Primate lineage specification requires suppression of Alu hyperediting
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  99. Editome profiling and cross-cohort validation reveal A-to-I RNA editing dysregulation in the hippocampus and prefrontal cortex of sepsis patients
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  100. Molecular Context of ADAR-Mediated Editing of Coding RNA in Colorectal and Lung Cancers
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