Genomic Hallmarks and Structural Variation in Metastatic Prostate Cancer
Quigley, David A., Dang, Ha X., Zhao, Shuang G., Lloyd, Paul, Aggarwal, Rahul, Alumkal, Joshi J., Foye, Adam, Kothari, Vishal +55 more·2018·Cell
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- Clinical implications of homologous recombination repair mutations in prostate cancerPablo Cresta Morgado, Joaquı́n Mateo · 2022 · The Prostate
- Genomic Biomarkers and Genome-Wide Loss-of-Heterozygosity Scores in Metastatic Prostate Cancer Following Progression on Androgen-Targeting TherapiesAmado J. Zurita, Ryon P. Graf, Guillermo Javierre Villacampa, Kira Raskina, Ethan S. Sokol, Dexter X. Jin, Emmanuel S. Antonarakis, Gerald Li, Richard S.P. Huang, Irene Casanova‐Salas et al. · 2022 · JCO Precision Oncology
- Predicting response to enzalutamide and abiraterone in metastatic prostate cancer using whole-omics machine learningAnouk C. de Jong, Alexandra Danyi, Job van Riet, Ronald de Wit, Martin Sjöström, Felix Yi-Chung Feng, Jeroen de Ridder, Martijn P. Lolkema · 2023 · Nature Communications
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- High-Purity CTC RNA Sequencing Identifies Prostate Cancer Lineage Phenotypes Prognostic for Clinical OutcomesMarina Nasrin Sharifi, Jamie M. Sperger, Amy K. Taylor, Katharine E. Tippins, Shannon R. Reese, Viridiana Carreno, Katherine R. Kaufmann, Alex Hong Chang, Luke A. Nunamaker, Charlotte Linebarger et al. · 2025 · Cancer Discovery
- Long Non-coding RNA AGAP2-AS1 Silencing Inhibits PDLIM5 Expression Impeding Prostate Cancer Progression via Up-Regulation of MicroRNA-195-5pPingbo Xie, Mingsheng Liu, Fen Chen, Shaomei Wu, Tao Shao, Wei Ting Wang, Chenxiang Xu, Hongqing Zhou · 2020 · Frontiers in Genetics
- Epigenetic and transcriptional analysis reveals a core transcriptional program conserved in clonal prostate cancer metastasesTesa Severson, Yanyun Zhu, Angelo Michael De Marzo, Tracy Jones, Jonathan W. Simons, William G. Nelson, Srinivasan Yegnasubramanian, Matthew L. Freedman, Lodewyk F.A. Wessels, Andries Marinus Bergman et al. · 2021 · Molecular Oncology
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- Molecular Pathology of Prostate Cancerİbrahim Kulaç, Martine P. Roudier, Michael C. Haffner · 2024 · Clinics in Laboratory Medicine
- Intraindividual epigenetic heterogeneity underlying phenotypic subtypes of advanced prostate cancerKei Mizuno, Sheng‐Yu Ku, Varadha Balaji Venkadakrishnan, Martin K. Bakht, Michael Sigouros, Joanna Chan, Anna Trigos, Jordan H. Driskill, Jyothi Manohar, Abigail S. King et al. · 2025 · Nature Communications
- Perspectives on Circular RNAs as Prostate Cancer BiomarkersJiajie Fang, Jianfei Qi, Xuesen Dong, Jindan Luo · 2020 · Frontiers in Cell and Developmental Biology
- Association between pathogenic germline mutations in BRCA2 and ATM and tumor-infiltrating lymphocytes in primary prostate cancerHarsimar B. Kaur, Thiago Vidotto, Adrianna Amaral de Aragao Mendes, Daniela Correia Salles, William B. Isaacs, Emmanuel S. Antonarakis, Tamara Levin Lotan · 2021 · Cancer Immunology Immunotherapy
- Baseline Plasma Tumor DNA (ctDNA) Correlates with PSA Kinetics in Metastatic Castration-Resistant Prostate Cancer (mCRPC) Treated with Abiraterone or EnzalutamideVincenza Conteduca, Chiara Casadei, Emanuela Scarpi, Nicole Brighi, Giuseppe Schepisi, Cristian Lolli, Giorgia Gurioli, Ilaria Toma, Giulia Poti, Alberto Farolfi et al. · 2022 · Cancers
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- Integration of whole-exome and anchored PCR-based next generation sequencing significantly increases detection of actionable alterations in precision oncologyShaham Beg, Rohan Bareja, Kentaro Ohara, Kenneth Eng, David C. Wilkes, David J. Pisapia, Wael Al Zoughbi, Sarah Kudman, Wei Zhang, Rema A. Rao et al. · 2020 · Translational Oncology
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- Molecular Pathology of Prostate Cancerİbrahim Kulaç, Martine P. Roudier, Michael C. Haffner · 2021 · Surgical pathology clinics
- Nivolumab in Patients with Metastatic Castration-Resistant Prostate Cancer with and without DNA Repair DefectsPedro Isaacsson Velho, Diogo Assed Bastos, Pedro Tofani Saint’ana, Brenda Rigatti, Emily Tonin da Costa, David Queiroz Borges Muniz, Felipe Andreis, Rafael Dal Ponte Ferreira, Luana Giongo Pedrotti, Simone Maistro et al. · 2024 · Clinical Cancer Research
- Androgen receptor reprogramming demarcates prognostic, context-dependent gene sets in primary and metastatic prostate cancerTesa Severson, Xintao Qiu, Mohammed Alshalalfa, Martin Sjöström, David Alan Quigley, Andries Marinus Bergman, Henry W. Long, Felix Yi-Chung Feng, Matthew L. Freedman, Wilbert T. Zwart et al. · 2022 · Clinical Epigenetics
- The role of glutamine metabolism in castration-resistant prostate cancerBing Qiang Zhao, Jing Wang, Li Chen, Hong Wang, Chao-Zhao Liang, Jiaoti Huang, Lingfan Xu · 2023 · Asian Journal of Andrology
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- Current uses and resistance mechanisms of enzalutamide in prostate cancer treatmentCarly D. Miller, Pornlada Likasitwatanakul, Eamon Toye, Justin H. Hwang, Emmanuel S. Antonarakis · 2024 · Expert Review of Anticancer Therapy
- Plasma Cell–Free DNA Chromatin Immunoprecipitation Profiling Depicts Phenotypic and Clinical Heterogeneity in Advanced Prostate CancerJoonatan Sipola, Aslı D. Munzur, Edmond M. Kwan, Clara C. Y. Seo, Benjamin J. Hauk, Karan Parekh, Yi Jou Liao, Cecily Q. Bernales, Gráinne Donnellan, Ingrid Bloise et al. · 2024 · Cancer Research
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- Expanding cancer predisposition genes with ultra-rare cancer-exclusive human variationsRoni Rasnic, Nathan Linial, Michal Linial · 2020 · Scientific Reports
- Large remodeling of the Myc-induced cell surface proteome in B cells and prostate cells creates new opportunities for immunotherapyWentao Chen, Kurt Yun Mou, Paige E. Solomon, Rahul Raj Aggarwal, Kevin Leung, James A. Wells · 2021 · Proceedings of the National Academy of Sciences
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- Metastatic Castration-Resistant Prostate Cancer Remains Dependent on Oncogenic Drivers Found in Primary TumorsDavid Johnson Einstein, Seiji Arai, Carla Calagua, Fang Xie, Olga S. Voznesensky, Brian J. Capaldo, Christina I. Luffman, Jonathan L. Hecht, Steven P. Balk, Adam G. Sowalsky et al. · 2021 · JCO Precision Oncology
- Enzalutamide-induced signatures revealed by epigenetic plasticity using single-cell multi-omics sequencing in prostate cancerFan, Huihui, Li, Jinze, Manuel, Astrid M., Zhao, Zhongming · 2023 · Molecular Therapy - Nucleic Acids
- Real-world data on the prevalence of BRCA1/2 and HRR gene mutations in patients with primary and metastatic castration resistant prostate cancerMoritz Hommerding, Oliver Hommerding, Marit Bernhardt, Tobias Kreft, Christine Sanders, Verena Tischler, Patrick Basitta, Natalie Pelusi, Anna‐Lena Wulf, Carsten‐Henning Ohlmann et al. · 2024 · World Journal of Urology
- The Emerging Predictive and Prognostic Role of Aggressive-Variant-Associated Tumor Suppressor Genes Across Prostate Cancer StagesMartino Pedrani, Jessica Barizzi, Giuseppe Salfi, Alessandro Nepote, Irene Testi, Sara Merler, Luís Castelo-Branco, Ricardo Pereira Mestre, Fabio Turco, Luigi Tortola et al. · 2025 · International Journal of Molecular Sciences
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- Precision Targets for Intercepting the Lethal Progression of Prostate Cancer: Potential Avenues for Personalized TherapyMax Christenson, Chung Seog Song, Yaguang Liu, Bandana Chatterjee · 2022 · Cancers
- Metastatic Prostate Cancers with BRCA2 versus ATM Mutations Exhibit Divergent Molecular Features and Clinical OutcomesJustin H. Hwang, Xiaolei Shi, Andrew Elliott, Taylor E. Arnoff, Julie McGrath, Joanne Xiu, Phillip Walker, Hannah E. Bergom, Abderrahman Day, Shihab Ahmed et al. · 2023 · Clinical Cancer Research
- Genomic and Epigenomic Analysis of Plasma Cell-Free DNA Identifies Stemness Features Associated with Worse Survival in Lethal Prostate CancerPradeep S. Chauhan, Irfan Alahi, Savar D. Sinha, Elisa Marie Ledet, Ryan Mueller, Jessica Linford, Alexander L. Shiang, Jace B. Webster, Lilli J. Greiner, Breanna Yang et al. · 2024 · Clinical Cancer Research
- Genomic and transcriptomic features of androgen receptor signaling inhibitor resistance in metastatic castration-resistant prostate cancerXiaolin Zhu, Tatyanah Farsh, Daniël J. Vis, Ivan Pak Lok Yu, Haolong Li, Tianyi Liu, Martin Sjöström, Raunak Shrestha, Jeroen Kneppers, Tesa Severson et al. · 2024 · Journal of Clinical Investigation
- Increased nuclear factor I-mediated chromatin access drives transition to androgen receptor splice variant dependence in prostate cancerLarysa Poluben, Mannan Nouri, Jiaqian Liang, Shaoyong Chen, Andreas S. Varkaris, Betul Ersoy-Fazlioglu, Olga S. Voznesensky, Irene I. Lee, Xintao Qiu, Laura Cato et al. · 2024 · Cell Reports
- Multiplex Digital PCR to Detect Amplifications of Specific Androgen Receptor Loci in Cell-Free DNA for Prognosis of Metastatic Castration-Resistant Prostate CancerMeijun Du, Chiang‐Ching Huang, Winston W. Tan, Manish Kohli, Liang Wang · 2020 · Cancers
- The Role of PARP Inhibitors in the Treatment of Prostate Cancer: Recent Advances in Clinical TrialsMingyue Xia, Zhigang Guo, Zhigang Hu · 2021 · Biomolecules
- Clinical reliability of genomic data obtained from spinal metastatic tumor samplesOri Barzilai, Axel Martin, Anne S Reiner, Ilya Laufer, Adam M. Schmitt, Mark H Bilsky · 2022 · Neuro-Oncology
- Generation of prostate cancer assembloids modeling the patient-specific tumor microenvironmentJ.-H. Lee, Yun‐Hee Kim, Cheolmin Matthew Lee, Seong Soo Jeon, H.K. Seo, Jong Won Lee, Jungmin Choi, Minyong Kang, Eunjee Kim, Kunyoo Shin · 2025 · PLoS Genetics
- Emerging therapies to overcome antiandrogen resistance and beyond in lethal prostate cancerFurong Huang, Kexin Li, Jeffrey W. Shevach, Qianben Wang · 2025 · Journal of the National Cancer Center
- Non-drug efflux function of ABCC5 promotes enzalutamide resistance in castration-resistant prostate cancer via upregulation of P65/AR-V7Haojie Chen, Jia Luo, Shaojun Chen, Bowen Shi, Xiaocui Zheng, Haiying Ji, Xiaoqian Zhang, Yujia Yin, Kun Du, Jie Ding et al. · 2022 · Cell Death Discovery
- Androgen receptor signaling and spatial chromatin organization in castration-resistant prostate cancerTianyi Zhou, Qin Fu Feng · 2022 · Frontiers in Medicine
- PARP Inhibitors in Advanced Prostate Cancer in Tumors with DNA Damage SignaturesCiara S. McNevin, Karen Anne Cadoo, Anne‐Marie Baird, Stephen P. Finn, Ray McDermott · 2022 · Cancers
- Strategies to Re-Sensitize Castration-Resistant Prostate Cancer to Antiandrogen TherapyBelén Congregado Ruiz, Ines RIVERO BELENCHON, Guillermo Lendinez Cano, Rafael Antonio Medina López · 2023 · Biomedicines
- Autocrine activation of MAPK signaling mediates intrinsic tolerance to androgen deprivation in LY6D prostate cancer cellsIvana Steiner, Teresita del N.J. Flores-Téllez, Renaud Mével, Amin Ali, Pengbo Wang, Pietá Schofield, Caron Behan, Nicholas Forsythe, Garry Ashton, Cathy Taylor et al. · 2023 · Cell Reports
- Genomics and Artificial IntelligenceElyssa Y. Wong, Timothy N. Chu, Seyedeh‐Sanam Ladi‐Seyedian · 2023 · Urologic Clinics of North America
- The yin and yang of chromosomal instability in prostate cancerMarc Carceles‐Cordon, Jacob J. Orme, Josep M. Domingo Domenech, Verónica Rodríguez-Bravo · 2024 · Nature Reviews Urology
- N6-methyladenosine-modified circRPS6KC1 regulated cellular senescence in prostate cancer via FOXM1/PCNA axisXuan Shu, Jiahe Yi, Jiangfeng Li, Yufan Ying, Yijie Tang, Ziyan Chen, Jiaming Wang, Fenghao Zhang, Dingheng Lu, Yuqing Wu et al. · 2024 · Cellular Signalling
- Transcription and DNA replication collisions lead to large tandem duplications and expose targetable therapeutic vulnerabilities in cancerYang Yang, Michelle L. Badura, Patrick C. O’Leary, Henry M. Delavan, Troy M. Robinson, Emily A. Egusa, Xiaoming Zhong, Jason T. Swinderman, Haolong Li, Meng Zhang et al. · 2024 · Nature Cancer
- Acquired resistance to molecularly targeted therapies for cancerNolan M. Stubbs, Tyler J. Roady, Maximilian P. Schwermann, Elias O.U. Eteshola, William MacDonald, Connor Purcell, Dinara Ryspayeva, Nataliia Verovkina, Vida Tajiknia, Maryam Ghandali et al. · 2025 · Cancer Drug Resistance
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- Optical genome mapping identifies clinically relevant genomic rearrangements in prostate cancer biopsy sampleYeeun Shim, Jong Soo Lee, Ji-Eun Seo, Cheol Keun Park, Saeam Shin, Hyun Ho Han, Seung‐Tae Lee, Jong Rak Choi, Byung Ha Chung, Young Deuk Choi · 2022 · Cancer Cell International
- A correlative biomarker study and integrative prognostic model in chemotherapy‐naïve metastatic castration‐resistant prostate cancer treated with enzalutamideMaría Piedad Fernández-Pérez, Enrique Pérez, Teresa Alonso‐Gordoa, Vicenza Conteduca, Albert Font Pous, Sergio Vázquez‐Estévez, Aranzazu González del Alba, Daniel Wetterskog, Emmanuel S. Antonarakis, Begoña Mellado et al. · 2022 · The Prostate
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- Copy number architectures define treatment-mediated selection of lethal prostate cancer clonesA. M. Mahedi Hasan, Paolo Cremaschi, Daniel Wetterskog, Anuradha Jayaram, Stephen Q. Wong, Scott Williams, Anupama Pasam, Anna Trigos, Blanca Trujillo, Emily Grist et al. · 2023 · Nature Communications
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- Overexpression of Ubiquitin-Conjugating Enzyme E2C Is Associated with Worsened Prognosis in Prostate CancerXiaobo Wu, Xingbo Long, Chenkai Ma, Yin Celeste Cheuk, Mengbo Hu, Jimeng Hu, Haowen Jiang · 2022 · International Journal of Molecular Sciences
- A generalizable machine learning framework for classifying DNA repair defects using ctDNA exomesElie J. Ritch, Cameron Herberts, Evan W. Warner, Sarah W.S. Ng, Edmond M. Kwan, Jack V. W. Bacon, Cecily Q. Bernales, Elena Schönlau, Nicolette M. Fonseca, Veda N. Giri et al. · 2023 · npj Precision Oncology
- KLF4 as a rheostat of osteolysis and osteogenesis in prostate tumors in the boneEvelyne Tassone, Vivian Bradaschia-Corrêa, Xiaozhong Xiong, Ana Sastre-Perona, Anne Marie Josephson, Alireza Khodadadi‐Jamayran, Jonathan Melamed, Lei Bu, David J. Kahler, Liliana Ossowski et al. · 2019 · Oncogene
- Molecular Underpinnings Governing Genetic Complexity of ETS-Fusion-Negative Prostate CancerVipul Bhatia, Bushra Ateeq · 2019 · Trends in Molecular Medicine
- Cancer transcriptomic profiling from rapidly enriched circulating tumor cellsGareth J. Morrison, Alexander T. Cunha, Nita Jojo, Yucheng Xu, Yili Xu, Eric Kwok, Peggy S. Robinson, Tanya Barauskas Dorff, David I. Quinn, John David Carpten et al. · 2020 · International Journal of Cancer
- Copy Number Loss of 17q22 Is Associated with Enzalutamide Resistance and Poor Prognosis in Metastatic Castration-Resistant Prostate CancerXiangnan Guan, Duanchen Sun, Eric Lu, Joshua A. Urrutia, Robert Evan Reiter, Matthew B. Rettig, Christopher P. Evans, Primo N. Lara, Martin Edwin Gleave, Tomasz M. Beer et al. · 2020 · Clinical Cancer Research
- Searching thousands of genomes to classify somatic and novel structural variants using STIXMurad Chowdhury, Brent S. Pedersen, Fritz Joachim Sedlazeck, Aaron R. Quinlan, Ryan M. Layer · 2022 · Nature Methods
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- From genomics to functions: preclinical mouse models for understanding oncogenic pathways in prostate cancer.Chuan Yu, Kevin M. Hu, Daniel Nguyen, Zhu A. Wang · 2019 · PubMed Central
- A novel prognostic model for prostate cancer based on androgen biosynthetic and catabolic pathwaysAoyu Fan, Yunyan Zhang, Jiangting Cheng, Yunpeng Li, Wei Chen · 2022 · Frontiers in Oncology
- The Impact of Whole Genome Data on Therapeutic Decision-Making in Metastatic Prostate Cancer: A Retrospective AnalysisMegan Crumbaker, Eva K.F. Chan, Tingting Gong, Niall M. Corcoran, Weerachai Jaratlerdsiri, Ruth J. Lyons, Anne‐Maree Haynes, Anna Kulidjian, Anton M.F. Kalsbeek, Desiree C. Petersen et al. · 2020 · Cancers
- Big Data to Knowledge: Application of Machine Learning to Predictive Modeling of Therapeutic Response in CancerSukanya Panja, Sarra M. Rahem, Cassandra Chu, Antonina Mitrofanova · 2020 · Current Genomics
- Impact of concurrent tumour events on the prostate cancer outcomes of germline BRCA2 mutation carriersRebeca Lozano, Elena Castro, Fernando López‐Campos, Heather Thorne, M. Backhaus, Isabel M. Aragón, Ylenia Cendón, Ana Gutiérrez-Pecharromán, Daniela Correia Salles, Nuria Romero-Laorden et al. · 2023 · European Journal of Cancer
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- Canonical androgen response element motifs are tumor suppressive regulatory elements in the prostateXuanrong Chen, Michael A. Augello, Deli Liu, Kevin Lin, Alex Hakansson, Martin Sjöström, Francesca Khani, Lesa Dayal Deonarine, Yang Liu, Jaida Travascio-Green et al. · 2024 · Nature Communications
- CRISPR screening identifies regulators of enhancer-mediated androgen receptor transcription in advanced prostate cancerRachel R. Xiang, Shin-Ai Lee, Caroline F. Tyndall, Anusha R. Bhatia, JuanJuan Yin, Cassandra Singler, Benjamin J. Hauk, Matthew P. Kipp, David Yoshio Takeda · 2025 · Cell Reports
- Epigenetic profiling identifies markers of endocrine resistance and therapeutic options for metastatic castration-resistant prostate cancerTesa Severson, Emma Minnee, Yanyun Zhu, Karianne G. Schuurman, Holly M. Nguyen, Lisha G. Brown, Sini Hakkola, Renée X. de Menezes, Sebastian Gregoricchio, Yongsoo Kim et al. · 2025 · Cell Reports Medicine
- Germline and Somatic Defects in DNA Repair Pathways in Prostate CancerSara Arce‐Gallego, Alejandro Athie, Colin C. Pritchard, Joaquı́n Mateo · 2019 · Advances in experimental medicine and biology
- Continued androgen signalling inhibition improves cabazitaxel efficacy in prostate cancerLisanne Mout, Martin E. van Royen, Corrina de Ridder, Debra C. Stuurman, Wesley S. van de Geer, Rute B. Marques, Stefan A.J. Buck, Pim J. French, Harmen J.G. van de Werken, Ron H.J. Mathijssen et al. · 2021 · EBioMedicine
- Stat5 induces androgen receptor ( AR ) gene transcription in prostate cancer and offers a druggable pathway to target AR signalingCristina Maranto, Lavannya Sabharwal, Vindhya Udhane, Samuel P. Pitzen, Braedan M. McCluskey, Songyan Qi, Christine L. O’Connor, Savita Devi, Scott C. Johnson, Kenneth M. Jacobsohn et al. · 2024 · Science Advances
- Prostate Cancer Genomic SubtypesMichael E. Fraser, Alexandre Rouette · 2019 · Advances in experimental medicine and biology
- RGS2 is prognostic for development of castration resistance and cancer‐specific survival in castration‐resistant prostate cancerAnna Linder, Karin Larsson, Karin Welén, Jan‐Erik Damber · 2020 · The Prostate
- The androgen receptor-targeted proteolysis targeting chimera and other alternative therapeutic choices in overcoming the resistance to androgen deprivation treatment in prostate cancerLiuxun Li, Jiangli Xu · 2022 · Clinical & Translational Oncology
- Single cell multi-omics analysis of chromothriptic medulloblastoma highlights genomic and transcriptomic consequences of genome instabilityRodrigo Parra, Moritz Jakob Przybilla, Milena Simovic-Lorenz, Hana Sušak, Manasi Ratnaparkhe, John KL Wong, Verena Körber, Jan‐Philipp Mallm, Martin Sill, Thorsten Kolb et al. · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
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- The future of androgen receptor targeting in prostate cancer: third-generation inhibitors and beyondAlice Bernard‐Tessier, Natacha Naoun, Solenn Barraud, Ronan Flippot, Cédric Pobel, Macarena Rey, Capucine Baldini, Christophe Massard, Anna Patrikidou, Alina Cristina Fuerea et al. · 2025 · Therapeutic Advances in Medical Oncology
- Joint analysis of WES and RNA‐Seq identify signature genes related to metastasis in prostate cancerChongjun Xiang, Yue Li, Wenting Wang, Huiying Tao, Ning Liang, Shuang Wu, Tianxi Yu, Xin Cui, Yaqi Xie, Hongwei Zuo et al. · 2023 · Journal of Cellular and Molecular Medicine
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