Genomic Hallmarks and Structural Variation in Metastatic Prostate Cancer

Quigley, David A., Dang, Ha X., Zhao, Shuang G., Lloyd, Paul, Aggarwal, Rahul, Alumkal, Joshi J., Foye, Adam, Kothari, Vishal +55 more·2018·Cell

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  1. Platinum Chemotherapy After PARP Inhibition in HRR-Deficient Metastatic Castration-Resistant Prostate Cancer
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  2. DNA Repair Capacity and Clinicopathological Characteristics in Puerto Rican Hispanic/Latino Patients with Metastatic Castration-Resistant Prostate Cancer
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  5. CDK12 Deficiency Induces BRD4S to Promote Cancer Metastasis by Enhancing Phase Separation and Chromatin Engagement
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  8. Unravelling TPX2-centered co-expression networks as key drivers of aggressive prostate cancer
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  10. Assessing the Detection Power of Genome-Wide Copy Number Variation Profiles in Prostate Cancer Using Simulated Shallow Whole-Genome Sequencing Data
    Samhita Pamidimarri Naga, Peter H. J. Slootbeek, Sofie H. Tolmeijer, Christian Gilissen, Marjolijn J. L. Ligtenberg, Niven Mehra, Richarda M. de Voer · 2026 · JCO Clinical Cancer Informatics
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  13. Targeting the RNA-binding motif protein 15 suppresses prostate cancer progression and hormone therapy resistance by promoting androgen receptor degradation
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  14. Integrative molecular analyses of lineage identity and morphology in aggressive variant prostate cancer
    Chennan Li, JuanJuan Yin, Melissa L. Abel, Dana S. Vargas Solivan, Kinjal P. Bhadresha, Sumeyra Kartal, Samantha Nichols, Kanak Parmar, Joseph D. Twohig, Tri M. Truong et al. · 2026 · npj Precision Oncology
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  24. Personalized Medicine: Leave no Patient Behind; Report From the 2024 Coffey‐Holden Prostate Cancer Academy Meeting
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  30. Separating the Dreadful from the Merely Bad: Towards Prognostic and Predictive Biomarkers in Metastatic Castration-resistant Prostate Cancer
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  31. The Telomere Length Landscape of Prostate Cancer
    Julie M. Livingstone, Yu-Jia Shiah, Takafumi N. Yamaguchi, Lawrence E. Heisler, Vincent Huang, Robert Lesurf, Tsumugi Gebo, Benjamin Carlin, Stefan E. Eng, Erik Drysdale et al. · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
  32. Unravelling the Role of Iroquois Homeobox 4 and its Interplay with Androgen Receptor in Prostate Cancer
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  33. Dosage Amplification Dictates Oncogenic Regulation by the NKX2-1 Lineage Factor in Lung Adenocarcinoma
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  34. Genomic and epigenomic analysis of plasma cell-free DNA identifies stemness features associated with worse survival in AR -altered lethal prostate cancer
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  35. Increased chromatin accessibility mediated by nuclear factor I drives transition to androgen receptor splice variant dependence in castration-resistant prostate cancer
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  36. Molecular consequences of acute versus chronic CDK12 loss in prostate carcinoma nominates distinct therapeutic strategies
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  37. TMPRSS2-ERG confers resistance to antiandrogens: mechanism and therapeutic implications
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  38. Molecular consequences of acute versus chronic CDK12 loss in prostate carcinoma nominates distinct therapeutic strategies
    Sander B. Frank, Thomas W. Persse, Ilsa Coleman, Armand Bankhead, Dapei Li, Navonil De Sarkar, Divin Wilson, Dmytro Rudoy, Manasvita Vashisth, Patty Galipeau et al. · 2025 · eLife
  39. Molecular decoupling of lineage identity and morphology in aggressive variant prostate cancer
    Chennan Li, JuanJuan Yin, Melissa L. Abel, Dana S. Vargas Solivan, Kinjal P. Bhadresha, Sumeyra Kartal, Samantha Nichols, Kanak Parmar, Joseph D. Twohig, Tri M. Truong et al. · 2026 · medRxiv
  40. Chromatin reprogramming as adaptation mechanism in advanced prostate cancer
    Alfonso Urbanucci · 2018 · European Urology Supplements
  41. Towards a New Classification for Metastatic Prostate Cancer
    Joaquı́n Mateo, Joan Carles · 2018 · European Urology
  42. Clinical implications of genetic aberrations in metastatic prostate cancer
    Zachery Roger Reichert, Rana R. McKay · 2019 · Current Opinion in Urology
  43. Genomic aberration based molecular signatures efficiently characterize homologous recombination deficiency in prostate cancer
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  44. Single-cell dissection of a rare human prostate basal cell carcinoma
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  45. AR Gain: Resistance Mechanism or Measure of Tumor Burden?
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  46. Low ribosomal RNA genes copy number provoke genomic instability and chromosomal segment duplication events that modify global gene expression and plant-pathogen response
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  50. Genomic Analysis And Engineering Of Chinese Hamster Ovary Cells For Improved Therapeutic Protein Production
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