Defining the genetic, genomic, cellular, and diagnostic architectures of psychiatric disorders

Sullivan, Patrick F., Geschwind, Daniel H.·2019·Cell

Cited by (476)

Items 101–200 of 476

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    Nagahide Takahashi, Tomoko Nishimura, Taeko Harada, Akemi Okumura, Damee Choi, Toshiki Iwabuchi, Hitoshi Kuwabara, Shu Takagai, Yoko Nomura, Jeffrey H. Newcorn et al. · 2020 · Translational Psychiatry
  2. Genome‐wide analysis reveals genetic overlap between alcohol use behaviours, schizophrenia and bipolar disorder and identifies novel shared risk loci
    Erik D Wiström, Kevin Sean O’Connell, Naz Karadag, Shahram Bahrami, Guy Hindley, Aihua Lin, Weiqiu Cheng, Nils Eiel Steen, Alexey A. Shadrin, Oleksandr Frei et al. · 2021 · Addiction
  3. Multivariate genomic analysis of 1.5 million people identifies genes related to addiction, antisocial behavior, and health
    Richard Karlsson Linnér, T. Mallard, Peter B. Barr, S. Sanchez-Roige, J. Madole, Morgan N. Driver, H. Poore, A. Grotzinger, J. Tielbeek, E. Johnson et al. · 2020 · bioRxiv
  4. Genetic Identification of Cell Types Underlying Brain Complex Traits Yields Novel Insights Into the Etiology of Parkinson’s Disease
    Julien Bryois, Nathan Skene, Thomas Folkmann Hansen et al. · 2019 · bioRxiv (Cold Spring Harbor Laboratory)
  5. Focal adhesion is associated with lithium response in bipolar disorder: evidence from a network-based multi-omics analysis
    Vipavee Niemsiri, Sara Brin Rosenthal, Caroline M. Nievergelt, Adam X. Maihofer, Maria Carolina Marchetto, Renata Santos, Tatyana Shekhtman, Ney Alliey‐Rodriguez, Amit Anand, Yokesh Balaraman et al. · 2023 · Molecular Psychiatry
  6. An Atlas of Gene Regulatory Elements in Adult Mouse Cerebrum
    Li, Yang Eric, Preissl, Sebastian, Hou, Xiaomeng, Zhang, Ziyang, Zhang, Kai, Fang, Rongxin, Qiu, Yunjiang, Poirion, Olivier, Li, Bin, Liu, Hanqing et al. · 2020
  7. Genetic contributions to transdiagnostic symptom dimensions in patients with major depressive disorder, bipolar disorder, and schizophrenia spectrum disorders
    Friederike Sophie David, Frederike Stein, Till F. M. Andlauer, Fabian Streit, Stephanie H. Witt, Stefan Herms, Per Hoffmann, Stefanie Heilmann‐Heimbach, Nils Opel, Jonathan Repple et al. · 2023 · Schizophrenia Research
  8. Polygenic risk for schizophrenia and schizotypal traits in non-clinical subjects
    Igor Nenadić, Tina Meller, Simon Schmitt, Frederike Stein, Katharina Brosch, Johannes Mosebach, Ulrich Ettinger, Phillip S. Grant, Susanne Meinert, Nils Opel et al. · 2020 · Psychological Medicine
  9. How genetic analysis may contribute to the understanding of avoidant/restrictive food intake disorder (ARFID)
    Kennedy, Hannah L., Dinkler, Lisa, Kennedy, Martin A., Bulik, Cynthia M., Jordan, Jennifer · 2022 · Journal of Eating Disorders
  10. What next for eating disorder genetics? Replacing myths with facts to sharpen our understanding
    Laura M. Huckins, Rebecca H. Signer, Jessica Johnson, Ya‐Ke Wu, Karen S. Mitchell, Cynthia Marie Bulik · 2022 · Molecular Psychiatry
  11. Axin2 coupled excessive Wnt‐glycolysis signaling mediates social defect in autism spectrum disorders
    Mengmeng Wang, Panpan Xian, Weian Zheng, Zhenzhen Li, Andi Chen, Haoxiang Xiao, Chao Xu, Fei Wang, Honghui Mao, Han Meng et al. · 2023 · EMBO Molecular Medicine
  12. Big Data Begin in Psychiatry
    Myrna M. Weissman · 2020 · JAMA Psychiatry
  13. Prediction of Alzheimer’s disease-specific phospholipase c gamma-1 SNV by deep learning-based approach for high-throughput screening
    Sung-Hyun Kim, Sumin Yang, Key‐Hwan Lim, Euiseng Ko, Hyun‐Jun Jang, Mingon Kang, Pann‐Ghill Suh, Jae‐Yeol Joo · 2021 · Proceedings of the National Academy of Sciences
  14. Phenotypic complexities of rare heterozygous neurexin-1 deletions
    Michael B. Fernando, Yu Fan, Yanchun Zhang, Alex Tokolyi, Aleta Murphy, Sarah Kammourh, P. J. Michael Deans, Sadaf Ghorbani, Ryan Onatzevitch, Adriana Pero et al. · 2025 · Nature
  15. Refining Attention-Deficit/Hyperactivity Disorder and Autism Spectrum Disorder Genetic Loci by Integrating Summary Data From Genome-wide Association, Gene Expression, and DNA Methylation Studies
    Anke R. Hammerschlag, Enda M. Byrne, Mawussé D. T. Agbessi, Habibul Ahsan, Isabel Alves, Anand Kumar Andiappan, Wibowo Arindrarto, Philip Awadalla, Alexis J. Battle, Frank Beutner et al. · 2020 · Biological Psychiatry
  16. The benefit of diagnostic whole genome sequencing in schizophrenia and other psychotic disorders
    Anna Alkelai, Lior Greenbaum, Anna R. Docherty, Andrey A. Shabalin, Gundula Povysil, Ayan Malakar, Daniel Hughes, Shannon L. Delaney, Emma P. Peabody, James McNamara et al. · 2021 · Molecular Psychiatry
  17. Current challenges and possible future developments in personalized psychiatry with an emphasis on psychotic disorders
    Аnastasia Levchenko, Timur Nurgaliev, Alexander A Kanapin, Anastasia A. Samsonova, Raul R. Gainetdinov · 2020 · Heliyon
  18. Identifying pleiotropic genes for complex phenotypes with summary statistics from a perspective of composite null hypothesis testing
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  19. DNA methylation in regulatory elements of the FKBP5 and NR3C1 gene in mother-child binomials with depression
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  20. Recent Developments in Autism Genetic Research: A Scientometric Review from 2018 to 2022
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  21. A matter of space and time: Emerging roles of disease-associated proteins in neural development
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  22. Investigating genetic links between grapheme–colour synaesthesia and neuropsychiatric traits
    Amanda K. Tilot, Arianna Vino, Katerina S. Kucera, Duncan A. Carmichael, Loes van den Heuvel, Joery den Hoed, Anton V. Sidoroff-Dorso, Archie Campbell, David John Porteous, Beaté St Pourcain et al. · 2019 · Philosophical Transactions of the Royal Society B Biological Sciences
  23. A study of genetic heterogeneity in autism spectrum disorders based on plasma proteomic and metabolomic analysis: multiomics study of autism heterogeneity
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  24. Polygenic risk scores in psychiatry – Large potential but still limited clinical utility
    Olav Bjerkehagen Smeland, Ole A. Andreassen · 2021 · European Neuropsychopharmacology
  25. Structural variants identified using non-Mendelian inheritance patterns advance the mechanistic understanding of autism spectrum disorder
    David Kainer, Alan R. Templeton, Erica Teixeira Prates, Daniel Jacboson, Euan R.O. Allan, Sharlee Climer, Michael R. Garvin · 2022 · Human Genetics and Genomics Advances
  26. Lessons Learned From Parsing Genetic Risk for Schizophrenia Into Biological Pathways
    Giulio Pergola, Nora Penzel, Leonardo Sportelli, Alessandro Bertolino · 2022 · Biological Psychiatry
  27. IPRS: Leveraging Gene-Environment Interaction to Reconstruct Polygenic Risk Score
    Yingdan Tang, Dongfang You, Honggang Yi, Sheng Yang, Yang Zhao · 2022 · Frontiers in Genetics
  28. From Personalized Medicine to Precision Psychiatry?
    Češková E, Šilhán P · 2021 · DOAJ (DOAJ: Directory of Open Access Journals)
  29. Causal relationships between blood lipids and major psychiatric disorders: Univariable and multivariable mendelian randomization analysis
    Bozhi Li, Yue Qu, Zhixin Fan, Xiayu Gong, Hanfang Xu, Lili Wu, Can Yan · 2023 · BMC Medical Genomics
  30. Integrating CRISPR Engineering and hiPSC-Derived 2D Disease Modeling Systems
    Kristina Rehbach, Michael B. Fernando, Kristen Brennand · 2020 · Journal of Neuroscience
  31. Stimulating Wnt signaling reveals context-dependent genetic effects on gene regulation in primary human neural progenitors
    Nana Matoba, Brandon D. Le, Jordan M. Valone, Justin M. Wolter, Jessica T. Mory, Dan Liang, Nil Aygün, K. Alaine Broadaway, Marielle L. Bond, Karen L. Mohlke et al. · 2024 · Nature Neuroscience
  32. Targeted sequencing and integrative analysis of 3,195 Chinese patients with neurodevelopmental disorders prioritized 26 novel candidate genes
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  33. A single-nucleotide polymorphism influences brain morphology in drug-naïve patients with major depressive disorder
    Asuka Katsuki, Shingo Kakeda, Keita Watanabe, Ryohei Igata, Yuka Otsuka, Taro Kishi, LeHoa Nguyen, Issei Ueda, Nakao Iwata, Yukunori Korogi et al. · 2019 · Neuropsychiatric Disease and Treatment
  34. Broad transcriptomic dysregulation across the cerebral cortex in ASD
    Jillian R. Haney, Brie Wamsley, George T Chen, Sepideh Parhami, Prashant S. Emani, Nathan Chang, Gil D. Hoftman, Diego de Alba, Gaurav Prashant Kale, Gokul Ramaswami et al. · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
  35. Inferring cell-type-specific causal gene regulatory networks during human neurogenesis
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  36. Leveraging Base Pair Mammalian Constraint to Understand Genetic Variation and Human Disease
    Patrick F. Sullivan, Jennifer R. S. Meadows, Steven Gazal et al. · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
  37. Decreased nuclear Pten in neural stem cells contributes to deficits in neuronal maturation
    Shin Chung Kang, Ritika Jaini, Masahiro Hitomi, Hyunpil Lee, Nick Sarn, Stetson Thacker, Charis Eng · 2020 · Molecular Autism
  38. CRISPR for neuroscientists
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  39. What a finding of gene copy number variation can add to the diagnosis of developmental neuropsychiatric disorders
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  40. Present and Future Modeling of Human Psychiatric Connectopathies With Brain Organoids
    Jean‐Paul Urenda, Ashley Del Dosso, Marcella Birtele, Giorgia Quadrato · 2022 · Biological Psychiatry
  41. Identification of relevant hub genes for early intervention at gene coexpression modules with altered predicted expression in schizophrenia
    Julio A. Rodriguez‐Lopez, Manuel Arrojo, Eduardo Paz, Mario Páramo, Javier Costas · 2019 · Progress in Neuro-Psychopharmacology and Biological Psychiatry
  42. Focus on Causality in ESC/iPSC-Based Modeling of Psychiatric Disorders
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  43. Effect of pharmacogenomic testing on the clinical treatment of patients with depressive disorder: A randomized clinical trial
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  44. A genome-wide association study identifies a gene network associated with paranoid schizophrenia and antipsychotics-induced tardive dyskinesia
    Аnastasia Levchenko, Alexander A Kanapin, Anastasia A. Samsonova, Olga Y. Fedorenko, Elena G. Kornetova, Timur Nurgaliev, Galina Elevna Mazo, Arkadiy V. Semke, Alexander O. Kibitov, Nikolay A. Bokhan et al. · 2020 · Progress in Neuro-Psychopharmacology and Biological Psychiatry
  45. Recapitulation of Perturbed Striatal Gene Expression Dynamics of Donors’ Brains With Ventral Forebrain Organoids Derived From the Same Individuals With Schizophrenia
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  46. What Do We Know About the Genetic Architecture of Psychopathology?
    Evan J. Giangrande, Ramona S. Weber, Eric Turkheimer · 2022 · Annual Review of Clinical Psychology
  47. The “missing heritability”—Problem in psychiatry: Is the interaction of genetics, epigenetics and transposable elements a potential solution?
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  48. Nanoparticle Based Gene Therapy Approach: A Pioneering Rebellion in the Management of Psychiatric Disorders
    Saleha Rehman, Bushra Nabi, Faheem Hyder Pottoo, Sanjula Baboota, Javed Ali · 2020 · Current Gene Therapy
  49. Massively parallel characterization of psychiatric disorder-associated and cell-type-specific regulatory elements in the developing human cortex
    2023
  50. Cell-type specific effects of genetic variation on chromatin accessibility during human neuronal differentiation
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  51. Dissecting the biology of feeding and eating disorders
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  52. Genome‐wide analyses reveal novel opioid use disorder loci and genetic overlap with schizophrenia, bipolar disorder, and major depression
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  53. Genetic Risk Assessment in Psychiatry
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  54. Overlap of neuroanatomical involvement in frontotemporal dementia and primary psychiatric disorders: a Meta-analysis
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  56. Anxiety Genetics Goes Genomic
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  57. Integration of Multimodal Data for Deciphering Brain Disorders
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  58. Unveiling the Pathogenesis of Psychiatric Disorders Using Network Models
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  59. Sodium hydrogen exchanger 9 NHE9 ( SLC9A9 ) and its emerging roles in neuropsychiatric comorbidity
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  61. Polygenicity in Psychiatry—Like It or Not, We Have to Understand It
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  86. Identifying loci with different allele frequencies among cases of eight psychiatric disorders using CC-GWAS
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