Widespread and Functional RNA Circularization in Localized Prostate Cancer

Chen, Sujun, Huang, Vincent, Xu, Xin, Livingstone, Julie, Soares, Fraser, Jeon, Jouhyun, Zeng, Yong, Hua, Junjie Tony +41 more·2019·Cell

Cited by (591)

Items 201–300 of 591

  1. Circular RNAs: Potential Star Molecules Involved in Diabetic Retinopathy
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  2. Characterization of circular RNAs with advanced sequencing technologies in human complex diseases
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  3. Investigating the Underlying Mechanisms of Circular RNAs and Their Application in Clinical Research of Cervical Cancer
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  4. The Role of Circular RNAs in DNA Damage Response and Repair
    Angelos Papaspyropoulos, Orsalia Georgia Hazapis, Nefeli Lаgopati, Aikaterini Polyzou, Anastasios D. Papanastasiou, Michalis Liontos, Vassilis G. Gorgoulis, Athanassios Kotsinas · 2021 · Cancers
  5. Intraductal Carcinoma of the Prostate as a Cause of Prostate Cancer Metastasis: A Molecular Portrait
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  6. MAGCDA: A Multi-Hop Attention Graph Neural Networks Method for CircRNA-Disease Association Prediction
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  7. Biological Roles and Clinical Significance of Exosome-Derived Noncoding RNAs in Bladder Cancer
    Yonghua Tong, Xiao Liu, Xia Ding, Ejun Peng, Xiaoqi Yang, Hailang Liu, Tao Ye, Xinguang Wang, Yu He, Hua Xu et al. · 2021 · Frontiers in Oncology
  8. Perspectives on Circular RNAs as Prostate Cancer Biomarkers
    Jiajie Fang, Jianfei Qi, Xuesen Dong, Jindan Luo · 2020 · Frontiers in Cell and Developmental Biology
  9. Identification of epithelial-mesenchymal transition-related circRNA-miRNA-mRNA ceRNA regulatory network in breast cancer
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  10. Circ_0040039 May Aggravate Intervertebral Disk Degeneration by Regulating the MiR-874-3p-ESR1 Pathway
    Yongjin Li, Xuke Wang, Haiwei Xu, Guowang Li, Zhenxin Huo, Lilong Du, Kaihui Zhang, Li Shen, Hao Li, Baoshan Xu · 2021 · Frontiers in Genetics
  11. Hsa_circ_0063329 inhibits prostate cancer growth and metastasis by modulating the miR-605-5p/tgif2 axis
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  12. Extracellular circular RNA profiles in plasma and urine of healthy, male college athletes
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  13. Identification of non-canonical peptides with moPepGen
    Chenghao Zhu, Lydia Liu, Annie Ha, Takafumi N. Yamaguchi, Helen He Zhu, Rupert Hugh-White, Julie M. Livingstone, Yash Patel, Thomas Kislinger, Paul Christopher Boutros · 2025 · Nature Biotechnology
  14. Identification and characterization of circular RNAs as novel putative biomarkers to predict anti-PD-1 monotherapy response in metastatic melanoma patients – Knowledge from two independent international studies
    Jian‐Guo Zhou, Rui Liang, Hai-Tao Wang, Su‐Han Jin, Wei Hu, Benjamin Frey, Rainer Fietkau, Markus Hecht, Hu Ma, Udo S. Gaipl · 2023 · Neoplasia
  15. Deep learning exploration of single-cell and spatially resolved cancer transcriptomics to unravel tumour heterogeneity
    Raid Halawani, Michael Büchert, Yi‐Ping Phoebe Chen · 2023 · Computers in Biology and Medicine
  16. CircAKT3 alleviates postoperative cognitive dysfunction by stabilizing the feedback cycle of miR-106a-5p/HDAC4/MEF2C axis in hippocampi of aged mice
    Xuan Wang, Xiaole Tang, Pengfei Zhu, Dong-Yu Hua, Zheng Xie, Mingke Guo, Mengxin Que, Jing Yan, Xing Li, Q. Xia et al. · 2024 · Cellular and Molecular Life Sciences
  17. METTL3-mediated m6A modification of circGLIS3 promotes prostate cancer progression and represents a potential target for ARSI therapy
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  18. Comprehensive scRNA-seq analysis to identify new markers of M2 macrophages for predicting the prognosis of prostate cancer
    Yitian Ou, Chengxing Xia, Chunwei Ye, Mingming Liu, Haiyang Jiang, Yong Zhu, Delin Yang · 2024 · Annals of Medicine
  19. Circular RNAs and Their Linear Transcripts as Diagnostic and Prognostic Tissue Biomarkers in Prostate Cancer after Prostatectomy in Combination with Clinicopathological Factors
    Hannah Rochow, Monika Jung, Sabine Weickmann, Bernhard Ralla, Carsten Stephan, Sefer Elezkurtaj, Ergin Kilic, Zhongwei Zhao, Klaus Jung, Annika Fendler et al. · 2020 · International Journal of Molecular Sciences
  20. CircGNG4 Promotes the Progression of Prostate Cancer by Sponging miR-223 to Enhance EYA3/c-myc Expression
    Shengxian Xu, Zhenpeng Lian, Siyang Zhang, Yong Jie Xu, Hongtuan Zhang · 2021 · Frontiers in Cell and Developmental Biology
  21. Prostate cancer multiparametric magnetic resonance imaging visibility is a tumor-intrinsic phenomena
    Amanda Khoo, Lydia Liu, Taylor Y. Sadun, Amirali Salmasi, Aydin H. Pooli, Ely Richard Felker, Kathleen E. Houlahan, Vladimir Ignatchenko, Steven S. Raman, Anthony E. JR. Sisk et al. · 2022 · Journal of Hematology & Oncology
  22. CircMiner: accurate and rapid detection of circular RNA through splice-aware pseudo-alignment scheme
    Hossein Asghari, Yen‐Yi Lin, Yang Xu, Ehsan Haghshenas, Colin C. Collins, Faraz Hach · 2020 · Bioinformatics
  23. A Novel Circular RNA circCSPP1 Promotes Liver Cancer Progression by Sponging miR-1182
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  24. Therapeutic SHPRH-146aa encoded by circ-SHPRH dynamically upregulates P21 to inhibit CDKs in neuroblastoma
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  25. Regulation of circGOLPH3 and its binding protein CBX7 on the proliferation and apoptosis of prostate cancer cells
    Lifeng Gong, Yu Tang, Jiang Li, Wei Tang, Shengjun Luo · 2020 · Bioscience Reports · Retracted
  26. RETRACTED ARTICLE: miR-217-5p Inhibits Invasion and Metastasis of Prostate Cancer by Targeting Clusterin
    Wanli Zhao, Xiuli Wang, Yuqing Jiang, Xiaopeng Jia, Yuexian Guo · 2021 · Mammalian Genome · Retracted
  27. Comprehensive analysis of circRNA expression pattern and circRNA-miRNA-mRNA network in oral squamous cell carcinoma
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  28. Identification of a Novel Angiogenesis Signalling circSCRG1/miR-1268b/NR4A1 Pathway in Atherosclerosis and the Regulatory Effects of TMP-PF In Vitro
    Rong Yuan, Qiqi Xin, Xiaochang Ma, Meng Yu, Yu Miao, Keji Chen, Weihong Cong · 2023 · Molecules
  29. Circ_BMP2K enhances the regulatory effects of miR-455-3p on its target gene SUMO1 and thereby inhibits the activation of cardiac fibroblasts
    Lei Zhang, Yunfei Bian, Rui Bai, Xiao-sun Song, Bin Liang, Chuanshi Xiao · 2020 · Biochemistry and Cell Biology
  30. Clinical utility of cerebrospinal fluid-derived circular RNAs in lung adenocarcinoma patients with brain metastases
    Zhen Wang, Ruoying Yu, Xiaoxi Chen, Hua Bao, Ran Cao, Anna Li, Qiuxiang Ou, Hai‐Yan Tu, Qing Hua Zhou, Xue Wu et al. · 2022 · Journal of Translational Medicine
  31. Prostate cancer in omics era
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  32. Overview of CircRNAs Roles and Mechanisms in Liver Fibrosis
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  33. RETRACTED: circPHIP promotes oral squamous cell carcinoma progression by sponging miR-142-5p and regulating PHIP and ACTN4 expression
    Wen Su, Yuehong Shen, Yufan Wang, Feng Wang, Hong Xia, Yuling Chen, Yuntao Lin, Hongyu Yang · 2020 · Molecular Therapy — Nucleic Acids · Retracted
  34. Genomic Features and Clinical Implications of Intraductal Carcinoma of the Prostate
    Minyong Kang, Hyunwoo Lee, Sun‐ju Byeon, Ghee Young Kwon, Seong Soo Jeon · 2021 · International Journal of Molecular Sciences
  35. Circ_0004676 exacerbates triple-negative breast cancer progression through regulation of the miR-377-3p/E2F6/PNO1 axis
    Guoli Shao, Xulong Fan, Pusheng Zhang, Xuewen Liu, Lei Huang, Shufeng Ji · 2022 · Cell Biology and Toxicology
  36. Prostate cancer: Novel genetic and immunologic biomarkers
    Mohammad Samare‐Najaf, Hosein Kouchaki, Seyed Moein Mahini, Masoumeh Saberi Rounkian, Yasaman Tavakoli, Ali N. Samareh, Mohammad Karim Azadbakht, Navid Jamali · 2024 · Clinica Chimica Acta
  37. Oncogenic ETS fusions promote DNA damage and proinflammatory responses via pericentromeric RNAs in extracellular vesicles
    Peter Ruzanov, Valentina E. Evdokimova, Manideep C. Pachva, Alon Minkovich, Zhenbo Zhang, Sofya Langman, Hendrik Gassmann, Uwe Thiel, Marija Orlic-Milacic, Syed Hassan Ejaz Zaidi et al. · 2024 · Journal of Clinical Investigation
  38. Emerging role of circular RNA in intervertebral disc degeneration: Knowns and unknowns (Review)
    Yongjin Li, Suzhe Zhou, Peng Peng, Xuke Wang, Lilong Du, Zhenxin Huo, Baoshan Xu · 2020 · Molecular Medicine Reports
  39. Immune-focused multi-omics analysis of prostate cancer: leukocyte Ig-Like receptors are associated with disease progression
    Benjamin Vittrant, Alain Bergeron, Oscar Eduardo Molina, Mickaël Leclercq, Xavier-Philippe Légaré, Hélène Hovington, Valérie Picard, Marie‐Laure Martin‐Magniette, Julie M. Livingstone, Paul Christopher Boutros et al. · 2020 · OncoImmunology
  40. DEBKS: A Tool to Detect Differentially Expressed Circular RNAs
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  41. Fusion transcripts and their genomic breakpoints in polyadenylated and ribosomal RNA–minus RNA sequencing data
    Youri Hoogstrate, Malgorzata A. Komor, René Böttcher, Job van Riet, Harmen J.G. van de Werken, Stef van Lieshout, Ralf Hoffmann, Evert van den Broek, Anne S. Bolijn, Natasja F. J. Dits et al. · 2021 · GigaScience
  42. The Germline and Somatic Origins of Prostate Cancer Heterogeneity
    Takafumi N. Yamaguchi, Kathleen E. Houlahan, Helen Zhu, Natalie Jayne Kurganovs, Julie M. Livingstone, Natalie S. Fox, Jiapei Yuan, Jocelyn Sietsma Penington, Chol-Hee Jung, Tommer Schwarz et al. · 2025 · Cancer Discovery
  43. NSUN2-mediated m5C modification of circFAM190B promotes lung cancer progression by inhibiting cellular autophagy
    Sixian Chen, Dunyu Cai, Qingyun Zhao, Jiaxi Wu, Xiaodong Zhou, Haotian Xu, Xiaofei Li, Ruirui Zhang, Wenyi Peng, Gang Li et al. · 2025 · International Journal of Biological Macromolecules
  44. The emerging role of circular RNAs in Parkinson’s disease
    Jiajia Liao, Qinxin Zhang, Jinjun Huang, Honghu He, Jiang Lei, Yuefei Shen, Jin Wang, Yousheng Xiao · 2023 · Frontiers in Neuroscience
  45. Circular RNA circARHGEF28 inhibited the progression of prostate cancer via the miR ‐671‐5p/ LGALS3BP / NF‐κB axis
    Kaixuan Guo, Juanyi Shi, Zhuang Tang, Cong Lai, Cheng Liu, Kuiqing Li, Zhuohang Li, Kewei Xu · 2023 · Cancer Science
  46. N6‐Methyladenosine Reader YTHDF2 Enhances Non‐Small‐Cell Lung Cancer Cell Proliferation and Metastasis through Mediating circ_SFMBT2 Degradation
    Jing Xu, Yan Shang, Xiong Qin, Yun Gai, Feng Cai, Hua Xiao, Chen Zhou, Youhui Fu, Xiahui Ge · 2022 · Contrast Media & Molecular Imaging
  47. The circRAB3IP Mediated by eIF4A3 and LEF1 Contributes to Enzalutamide Resistance in Prostate Cancer by Targeting miR-133a-3p/miR-133b/SGK1 Pathway
    Dong Chen, Yaqin Wang, Feiya Yang, Adili Keranmu, Qingxin Zhao, Liyuan Wu, Sujun Han, Nianzeng Xing · 2021 · Frontiers in Oncology
  48. Systematic loss-of-function screens identify pathway-specific functional circular RNAs
    Ling Liu, Matthew Neve, Laura Perlaza-Jiménez, Xinqi Xi, Jacob Purcell, Azelle Hawdon, Simon J. Conn, Jennifer Zenker, Pablo Tamayo, Gregory J. Goodall et al. · 2024 · Nature Cell Biology
  49. Silencing of circDPP4 suppresses cell progression of human prostate cancer and enhances docetaxel cytotoxicity through regulating the miR‐564/ZIC2 axis
    Hao Gu, Zhongqi Duan · 2021 · The Journal of Gene Medicine
  50. Prostate Cancer Transcriptomic Regulation by the Interplay of Germline Risk Alleles, Somatic Mutations, and 3D Genomic Architecture
    Jiapei Yuan, Kathleen E. Houlahan, Susmita Gurjar Ramanand, Sora Lee, GuemHee Baek, Yang Yang, Yong Chen, Douglas W. Strand, Michael Q. Zhang, Paul Christopher Boutros et al. · 2022 · Cancer Discovery
  51. The significance of PA28γ and U2AF1 in oral mucosal carcinogenesis
    Fengying Yin, Jiongke Wang, Kui Zhao, Chuan Xin, Yujie Shi, Xin Ying Zeng, Hao Ying Xu, Jing Li, Qianming Chen · 2019 · Oral Diseases
  52. hsa_circRNA6448-14 promotes carcinogenesis in esophageal squamous cell carcinoma
    Yaowen Zhang, Xiang Yuan, Ning Jeff Yue, Lidong Wang, Junqi Liu, Ningtao Dai, Haijun Yang, Ruitai Fan, Fuyou Zhou · 2020 · Aging
  53. Gene Expression Signatures of a Preclinical Mouse Model during Colorectal Cancer Progression under Low-Dose Metronomic Chemotherapy
    Hung Ho-Xuan, Gerhard J. Lehmann, Petar Glažar, Foivos Gypas, Norbert Eichner, Kevin Heizler, Hans Jürgen Schlitt, Mihaela Zavolan, Nikolaus Rajewsky, Gunter Meister et al. · 2020 · Cancers
  54. Roles of circRNAs in prostate cancer: Expression, mechanism, application and potential
    Chunlei Zhang, Qi Yang, Weiping Li, Yindong Kang, Fenghai Zhou, Dehui Chang · 2021 · The International Journal of Biochemistry & Cell Biology
  55. Deregulated expression and subcellular localization of CPSF6, a circRNA-binding protein, promote malignant development of esophageal squamous cell carcinoma
    Shichao Guo, Guangchao Wang, Zitong Zhao, Dan Li, Yongmei Song, Qimin Zhan · 2022 · Chinese Journal of Cancer Research
  56. Circular and Fusion RNAs in Medulloblastoma Development
    Ani Azatyan, Peter G. Zaphiropoulos · 2022 · Cancers
  57. SpliceV: analysis and publication quality printing of linear and circular RNA splicing, expression and regulation
    Nathan Ungerleider, Erik K. Flemington · 2019 · BMC Bioinformatics
  58. Tip of the iceberg: roles of circRNAs in hematological malignancies.
    Shanshan Guo, Bixia Li, Duobing Zou, Shu-Jun Yang, Lixia Sheng, Guifang Ouyang, Qitian Mu, He Huang · 2020 · PubMed Central
  59. Adipose exosomal noncoding RNAs: Roles and mechanisms in metabolic diseases
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  60. CD105+CAF-derived exosomes CircAMPK1 promotes pancreatic cancer progression by activating autophagy
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  61. CircUBA2 promotes the cancer stem cell-like properties of gastric cancer through upregulating STC1 via sponging miR-144-5p
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  62. Prostate cancer disease recurrence after radical prostatectomy is associated with HLA type and local cytomegalovirus immunity
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  63. CRIT: Identifying RNA-binding protein regulator in circRNA life cycle via non-negative matrix factorization
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  64. The RNA interactome in the Hallmarks of Cancer
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  65. circHIPK3 nucleates IGF2BP2 and functions as a competing endogenous RNA
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  66. Recent insights on the clinical, pathological, and molecular features of intraductal carcinoma of the prostate
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  67. The Emerging Role of Circular RNAs in Prostate Cancer: A Systematic Review
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  68. CircRNAs in Malignant Tumor Radiation: The New Frontier as Radiotherapy Biomarkers
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  69. The regulation of hsacirc_004413 promotes proliferation and drug resistance of gastric cancer cells by acting as a competing endogenous RNA for miR-145-5p
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  70. Gene Regulation Network Analysis on Human Prostate Orthografts Highlights a Potential Role for the JMJD6 Regulon in Clinical Prostate Cancer
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  74. CircAGFG1 absence decreases PKM2 expression to enhance oxaliplatin sensitivity in colorectal cancer in a miR-7-5p-dependent manner
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  76. Targeting PLOD2 suppresses invasion and metastatic potential in radiorecurrent prostate cancer
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  77. Modeling circRNA expression pattern with integrated sequence and epigenetic features demonstrates the potential involvement of H3K79me2 in circRNA expression
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  78. Circular RNA NF1-419 Inhibits Proliferation and Induces Apoptosis by Regulating Lipid Metabolism in Astroglioma Cells
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  80. An Integrative Transcriptomic and Methylation Approach for Identifying Differentially Expressed Circular RNAs Associated with DNA Methylation Change
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  81. Correction: Circ_BMP2K enhances the regulatory effects of miR-455-3p on its target gene SUMO1 and thereby inhibits the activation of cardiac fibroblasts
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  82. A detection model of testis‐derived circular RNAs in serum for predicting testicular sperm retrieval rate in non‐obstructive azoospermia patients
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  84. Circular RNA profiling identifies circ_0001522, circ_0001278, and circ_0001801 as predictors of unfavorable prognosis and drivers of triple-negative breast cancer hallmarks
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  85. Junction-targeting designs limit the application of CRISPR-Cas13d in circular RNA perturbation studies
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  86. CircRNome‐wide characterisation reveals the promoting role of circAATF in anti‐PD‐L1 immunotherapy of gallbladder carcinoma
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  87. Dysregulation of global circular RNA abundance regulated by spliceosomes predicts prognosis in hepatocellular carcinoma
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  88. A novel intronic circular RNA circFGFR1int2 up-regulates FGFR1 by recruiting transcriptional activators P65/FUS and suppressing miR-4687-5p to promote prostate cancer progression
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  89. CRISPRs in the human genome are differentially expressed between malignant and normal adjacent to tumor tissue
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  90. Emerging Functions and Roles of circRNAs in Cancer
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  91. Patient-matched analysis identifies deregulated networks in prostate cancer to guide personalized therapeutic intervention
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  93. Extracellular vesicle-mediated transmission of circPDLIM5 promotes lymphatic metastasis in prostate cancer
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  95. circHIPK3 nucleates IGF2BP2 and functions as a competing endogenous RNA
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  96. Circ_0006949 as a potential non-invasive diagnosis biomarker promotes the proliferation of NSCLC cells via miR-4673/GLUL axis
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  97. Long-range alternative splicing contributes to neoantigen specificity in glioblastoma
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  98. Dysregulated circular RNA and long non-coding RNA-Mediated regulatory competing endogenous RNA networks (ceRNETs) in ovarian and cervical cancers: A non-coding RNA-Mediated mechanism of chemotherapeutic resistance with new emerging clinical capacities
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  99. circEZH2E2 / E3 is a dual suppressor of miR363 / miR708 to promote EZH2 expression and prostate cancer progression
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  100. CircTENM3 inhibites tumor progression via the miR-558/RUNX3 axis in prostate cancer
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