The DOI matches its Crossref record; 49 of the 49 references it cites were found in a registry or an index.
Mammalian Near-Infrared Image Vision through Injectable and Self-Powered Retinal Nanoantennae
Open accessAbstract
Mammals cannot see light over 700 nm in wavelength. This limitation is due to the physical thermodynamic properties of the photon-detecting opsins. However, the detection of naturally invisible near-infrared (NIR) light is a desirable ability. To break this limitation, we developed ocular injectable photoreceptor-binding upconversion nanoparticles (pbUCNPs). These nanoparticles anchored on retinal photoreceptors as miniature NIR light transducers to create NIR light image vision with negligible side effects. Based on single-photoreceptor recordings, electroretinograms, cortical recordings, and visual behavioral tests, we demonstrated that mice with these nanoantennae could not only perceive NIR light, but also see NIR light patterns. Excitingly, the injected mice were also able to differentiate sophisticated NIR shape patterns. Moreover, the NIR light pattern vision was ambient-daylight compatible and existed in parallel with native daylight vision. This new method will provide unmatched opportunities for a wide variety of emerging bio-integrated nanodevice designs and applications. VIDEO ABSTRACT.
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NIR II-responsive photon upconversion through energy migration in an ytterbium sublattice
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“However, many other potential technologies have been developed alongside, including exosomes/liposomes, antisense oligonucleotides (AONs), electroporation of naked DNA/RNA, or application of nanoparticles [12,13].”
Background
Metadata
- Authors
- Ma, Y., Bao, J., Zhang, Y., Li, Z., Zhou, X., Wan, C., Huang, L., Zhao, Y., Han, G., & Xue, T.
- Venue
- Cell
- Publisher
- Elsevier BV
- Published
- 2019-04
- Volume
- 177
- Issue
- 2
- Pages
- 243-255.e15
- ISSN
- 0092-8674 (ISSN-L)
- OpenAlex
- W2916441868
- Cited by
- 292
- References
- 49
- FWCI
- 15.46
- Type
- journal article
- Language
- en
- Open access
- bronze
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- The paper
- Ma, Y., Bao, J., Zhang, Y., Li, Z., Zhou, X., Wan, C., Huang, L., Zhao, Y., Han, G., & Xue, T. (2019). Mammalian Near-Infrared Image Vision through Injectable and Self-Powered Retinal Nanoantennae. Cell. https://doi.org/10.1016/j.cell.2019.01.038
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