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Cited by 353

The DOI matches its Crossref record; 8 of the 8 references it cites were found in a registry or an index.

Mechanochemical Feedback Loops in Development and Disease

Open access
Hannezo, Edouard, Heisenberg, Carl-Philipp·2019·Cell

Abstract

There is increasing evidence that both mechanical and biochemical signals play important roles in development and disease. The development of complex organisms, in particular, has been proposed to rely on the feedback between mechanical and biochemical patterning events. This feedback occurs at the molecular level via mechanosensation but can also arise as an emergent property of the system at the cellular and tissue level. In recent years, dynamic changes in tissue geometry, flow, rheology, and cell fate specification have emerged as key platforms of mechanochemical feedback loops in multiple processes. Here, we review recent experimental and theoretical advances in understanding how these feedbacks function in development and disease.

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Metadata

Authors
Hannezo, E., & Heisenberg, C.-P.
Venue
Cell
Publisher
Elsevier BV
Published
2019-06
Volume
178
Issue
1
Pages
12-25
ISSN
0092-8674 (ISSN-L)
OpenAlex
W2955418269
Cited by
353
References
8
FWCI
17.84
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Mechanochemical Feedback Loops in Development and Disease. https://app.cochat.ai/papers/10.1016/j.cell.2019.05.052
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Hannezo, E., & Heisenberg, C.-P. (2019). Mechanochemical Feedback Loops in Development and Disease. Cell. https://doi.org/10.1016/j.cell.2019.05.052

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.