The DOI matches its Crossref record; 8 of the 8 references it cites were found in a registry or an index.
Mechanochemical Feedback Loops in Development and Disease
Open accessAbstract
There is increasing evidence that both mechanical and biochemical signals play important roles in development and disease. The development of complex organisms, in particular, has been proposed to rely on the feedback between mechanical and biochemical patterning events. This feedback occurs at the molecular level via mechanosensation but can also arise as an emergent property of the system at the cellular and tissue level. In recent years, dynamic changes in tissue geometry, flow, rheology, and cell fate specification have emerged as key platforms of mechanochemical feedback loops in multiple processes. Here, we review recent experimental and theoretical advances in understanding how these feedbacks function in development and disease.
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Cites
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Cited by
Mechanics and functional consequences of nuclear deformations
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Programmed and self-organized flow of information during morphogenesis
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Rigidity percolation uncovers a structural basis for embryonic tissue phase transitions
Petridou, N. I., Corominas-Murtra, B., Heisenberg, C.-P., & Hannezo, E. (2021) · Cell · doi:10.1016/j.cell.2021.02.017 · Cited by 222
Self-citationCell fate coordinates mechano-osmotic forces in intestinal crypt formation
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Metadata
- Authors
- Hannezo, E., & Heisenberg, C.-P.
- Venue
- Cell
- Publisher
- Elsevier BV
- Published
- 2019-06
- Volume
- 178
- Issue
- 1
- Pages
- 12-25
- ISSN
- 0092-8674 (ISSN-L)
- OpenAlex
- W2955418269
- Cited by
- 353
- References
- 8
- FWCI
- 17.84
- Type
- journal article
- Language
- en
- Open access
- bronze
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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