Cellular and Molecular Probing of Intact Human Organs

Zhao, Shan, Todorov, Mihail Ivilinov, Cai, Ruiyao, -Maskari, Rami AI, Steinke, Hanno, Kemter, Elisabeth, Mai, Hongcheng, Rong, Zhouyi +15 more·2020·Cell

Cited by (292)

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    Tingting Yu, Xiang Zhong, Dongyu Li, Jingtan Zhu, Valery Victorovich Tuchin, Dan Zhu · 2024 · Advanced Drug Delivery Reviews
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  7. Fundamental Neurochemistry Review: Incorporating a greater diversity of cell types, including microglia, in brain organoid cultures improves clinical translation
    Tyler J. Wenzel, Jennifer Le, Jim He, Jane Alcorn, Darrell D. Mousseau · 2022 · Journal of Neurochemistry
  8. Light sheet fluorescence microscopy of cleared human eyes
    Marie Darche, Ysé Borella, Anna Verschueren, Ivana Gantar, Stéphane Pagès, Laura Batti, Michel Pâques · 2023 · Communications Biology
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  10. Cellular maps of gastrointestinal organs: getting the most from tissue clearing
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  11. The Potential of OMICs Technologies for the Treatment of Immune-Mediated Inflammatory Diseases
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  12. Optical angiography for diabetes-induced pathological changes in microvascular structure and function: An overview
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  13. Placenta-derived factors contribute to human iPSC-liver organoid growth
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  14. Common principles in the lateralization of auditory cortex structure and function for vocal communication in primates and rodents
    Philip Ruthig, Marc Schönwiesner · 2022 · European Journal of Neuroscience
  15. 3D imaging of human organs with micrometer resolution - applied to the endocrine pancreas
    Max Hahn, Christoffer Nord, Maria Eriksson, Federico Morini, Tomas Alanentalo, Olle Korsgren, Ulf Ahlgren · 2021 · Communications Biology
  16. VIVIT: Resolving trans-scale volumetric biological architectures via ionic glassy tissue
    Yixiao Gao, Fengyuan Xin, Tao Wang, Chengjun Shao, Ying Hu, Zhuoya Chen, Yiwei Wang, Fenghua Xie, Tianyu Li, Sijie Li et al. · 2025 · Cell
  17. MarShie: a clearing protocol for 3D analysis of single cells throughout the bone marrow at subcellular resolution
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  18. Multi-omics and 3D-imaging reveal bone heterogeneity and unique calvaria cells in neuroinflammation
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  19. Diffusion tensor imaging‐based studies at the group‐level applied to animal models of neurodegenerative diseases
    Müller, Hans-Peter, Roselli, Francesco, Rasche, Volker, Kassubek, Jan · 2020 · Frontiers in Neuroscience
  20. High-Throughput Strategy for Profiling Sequential Section With Multiplex Staining of Mouse Brain
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  21. Unlocking the potential of large-scale 3D imaging with tissue clearing techniques
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  22. Perspectives in systems nephrology
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  23. Dec-DISCO: decolorization DISCO clearing for seeing through the biological architectures of heme-rich organs
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  24. Three-dimensional Imaging Coupled with Topological Quantification Uncovers Retinal Vascular Plexuses Undergoing Obliteration
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    Manako Yamaguchi, Kosuke Yoshihara, Nozomi Yachida, Kazuaki Suda, Ryo Tamura, Tatsuya Ishiguro, Takayuki Enomoto · 2021 · Journal of Personalized Medicine
  26. Multiplexed and scalable cellular phenotyping toward the standardized three-dimensional human neuroanatomy
    Tatsuya C. Murakami, Nathaniel Heintz · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
  27. 3D light-sheet fluorescence microscopy in preclinical and clinical drug discovery
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  28. Advances of novel hydrogels in the healing process of alveolar sockets
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  29. Organ-specific features of human kidney lymphatics are disrupted in chronic transplant rejection
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  32. 3D Whole-Brain Imaging Approaches to Study Brain Tumors
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  33. Tissue clearing and 3D imaging – putting immune cells into context
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  34. SUMIC: A Simple Ultrafast Multicolor Immunolabelling and Clearing Approach for Whole-Organ and Large Tissue 3D Imaging
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  35. Tissue Optical Clearing: State of the Art and Prospects
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  37. Whole‐Tumor Clearing and Imaging of Intratumor Microbiota in Three Dimensions with miCDaL Strategy
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  38. Unbiased analysis of obesity related, fat depot specific changes of adipocyte volumes and numbers using light sheet fluorescence microscopy
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  39. METGAN: Generative Tumour Inpainting and Modality Synthesis in Light Sheet Microscopy
    Izabela Horvath, Johannes Christian Paetzold, Oliver Schoppe, Rami Al-Maskari, Ivan Ezhov, Suprosanna Shit, Hongwei Li, Ali Ertürk, Bjoern H. Menze · 2022 · IEEE Winter Conference on Applications of Computer Vision
  40. Recent progress in optical clearing of eye tissues
    Wenhan Lu, Zhenle Pei, Wei Hu, Chen Tan, Xiaoyu Tong, Yi Feng, Xinghuai Sun · 2021 · Experimental Eye Research
  41. Hierarchical Random Walker Segmentation for Large Volumetric Biomedical Images
    Dominik Drees, Florian Eilers, Xiaoyi Jiang · 2022 · IEEE Transactions on Image Processing
  42. Maximizing content across scales: Moving multimodal microscopy and mesoscopy toward molecular imaging
    Sebastian Munck, Jim Swoger, Montserrat Coll‐Lladó, Nicola Gritti, Greetje Vande Velde · 2021 · Current Opinion in Chemical Biology
  43. Multidimensional Imaging of Breast Cancer
    Anne C. Rios, Jacco van Rheenen, Colinda L. G. J. Scheele · 2022 · Cold Spring Harbor Perspectives in Medicine
  44. Volume imaging to interrogate cancer cell-tumor microenvironment interactions in space and time
    Jorge Almagro, Hendrik A. Messal · 2023 · Frontiers in Immunology
  45. Mapping cellular targets of covalent cancer drugs in the entire mammalian body
    Zhengyuan Pang, Verina H. Leung, Cailynn C. Wang, Ahmadreza Attarpour, Anthony Rinaldi, Hanbing Shen, María Dolores Moya-Garzón, Logan H. Sigua, Claire Rammel, Alexandra Selke et al. · 2025 · Cell
  46. COMBINe enables automated detection and classification of neurons and astrocytes in tissue-cleared mouse brains
    Yuheng Cai, Xuying Zhang, Chen Li, H. Troy Ghashghaei, Alon Greenbaum · 2023 · Cell Reports Methods
  47. Three-dimensional mapping in multi-samples with large-scale imaging and multiplexed post staining
    Siqi Chen, Guangcai Liu, Anan Li, Zhixiang Liu, Ben Long, Xiao‐Quan Yang, Hui Gong, Xiangning Li · 2023 · Communications Biology
  48. Mapping the arterial vascular network in an intact human kidney using hierarchical phase-contrast tomography
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  49. Tissue Clearing Approaches in Atherosclerosis
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  50. Applications of tissue clearing in the spinal cord
    Ting Tian, Xiaoguang Li · 2020 · European Journal of Neuroscience
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    Mingqiang Lai, Wu Zhou, Wenchong Zou, Lianlian Qiu, Zhaoyu Liang, Wanyi Chen, Yiqing Wang, Bin Guo, Chaoran Zhao, Zhisheng Zhang et al. · 2025 · Nature Communications
  52. The Human Organ Atlas
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  53. Testing the suitability of neuroanatomical tracing method in human fetuses with long years of postmortem delay
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  55. Revealing intact neuronal circuitry in centimeter-sized formalin-fixed paraffin-embedded brain
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    Lingxi Meng, Xinyu Song, Junyi Wang, Wenxuan Shi, Liheng Gao, Xinquan Jiang, Wenjie Zhang · 2024 · BMEMat
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  59. A Cellular Ground Truth to Develop MRI Signatures in Glioma Models by Correlative Light Sheet Microscopy and Atlas-Based Coregistration
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  61. The Human Lung Cell Atlas: a transformational resource for cells of the respiratory system
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  63. Decoding the Mouse Spinal Cord Locomotor Neural Network Using Tissue Clearing, Tissue Expansion and Tiling Light Sheet Microscopy Techniques
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  64. Mapping the blood vasculature in an intact human kidney using hierarchical phase-contrast tomography
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  72. Seeing the Full Picture: Advances in 3D Cell Culture Microscopy
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