Proteogenomic Characterization Reveals Therapeutic Vulnerabilities in Lung Adenocarcinoma
Gillette, Michael A., Satpathy, Shankha, Cao, Song, Dhanasekaran, Saravana M., Vasaikar, Suhas V., Krug, Karsten, Petralia, Francesca, Li, Yize +178 more·2020·Cell
Cited by (846)
Items 201–300 of 846
- Targeted Proteomic Quantitation of NRF2 Signaling and Predictive Biomarkers in HNSCCNathan T. Wamsley, Emily Wilkerson, Li Guan, Kyle M. LaPak, Travis Parke Schrank, Brittany Holmes, Robert W. Sprung, Petra Erdmann-Gilmore, Sophie P. Gerndt, Ryan S. Jackson et al. · 2023 · Molecular & Cellular Proteomics
- Mutant RB1 enhances therapeutic efficacy of PARPis in lung adenocarcinoma by triggering the cGAS/STING pathwayQi Dong, Tong Yu, Bo Chen, Mingyue Liu, Xiang Sun, Huiying Cao, Kaidong Liu, Huanhuan Xu, Yuquan Wang, Shuping Zhuang et al. · 2023 · JCI Insight
- Comprehensive multi-omics analysis reveals WEE1 as a synergistic lethal target with hyperthermia through CDK1 super-activationXiaohang Yang, Xingyuan Hu, Jingjing Yin, Wenting Li, Yu Fu, Bin Yang, Junpeng Fan, Funian Lu, Tianyu Qin, Xiaoyan Kang et al. · 2024 · Nature Communications
- Extracellular Matrix Remodeling Alleviates Memory Deficits in Alzheimer's Disease by Enhancing the Astrocytic Autophagy‐Lysosome PathwayQinghu Yang, Chengxiang Yan, Yahan Sun, Zhen Xie, Liang Yang, Ming Jiang, Junjun Ni, Beining Chen, Sen Xu, Zhaoyue Yuan et al. · 2024 · Advanced Science
- Unifying multi-sample network inference from prior knowledge and omics data with CORNETOPablo Rodríguez-Mier, Martín Garrido‐Rodríguez, Attila Gábor, Julio Sáez-Rodríguez · 2025 · Nature Machine Intelligence
- Proteomic Analyses Identify Differentially Expressed Proteins and Pathways Between Low-Risk and High-Risk Subtypes of Early-Stage Lung Adenocarcinoma and Their Prognostic ImpactsJuntuo Zhou, Bing Liu, Zhongwu Li, Li Yang, Xi Chen, Yuanyuan Ma, Shi Yan, Xin Yang, Lijun Zhong, Nan Wu · 2020 · Molecular & Cellular Proteomics
- Identification of transcriptional subtypes in lung adenocarcinoma and squamous cell carcinoma through integrative analysis of microarray and RNA sequencing dataFrançois Fauteux, Anuradha Surendra, Scott McComb, Youlian Pan, Jennifer J. Hill · 2021 · Scientific Reports
- Glutathione peroxidase 8 expression on cancer cells and cancer‐associated fibroblasts facilitates lung cancer metastasisYulian Xu, Luo‐Wei Yuan, Xiaoming Jiang, Min‐Xia Su, Mu‐Yang Huang, Yu‐Chi Chen, Lele Zhang, Xiuping Chen, Hong‐Jian Zhu, Jin‐Jian Lu · 2022 · MedComm
- Mitochondrial Aconitase ACO2 Links Iron Homeostasis with Tumorigenicity in Non–Small Cell Lung CancerShideh Mirhadi, Wen Zhang, Nhu‐An Pham, Fereshteh Karimzadeh, Melania Pintilie, Jiefei Tong, Paul P. Taylor, Jonathan R. Krieger, Bethany Pitcher, Jenna R. Sykes et al. · 2022 · Molecular Cancer Research
- Pan-Cancer Proteomics Analysis to Identify Tumor-Enriched and Highly Expressed Cell Surface Antigens as Potential Targets for Cancer TherapeuticsJixin Wang, Wen Yu, Rachel K. D’Anna, Anna Przybyła, Matt Wilson, Matthew S. Sung, John Bullen, Elaine M. Hurt, Gina D’Angelo, Ben S. Sidders et al. · 2023 · Molecular & Cellular Proteomics
- PARP4 interacts with hnRNPM to regulate splicing during lung cancer progressionYi Fei Lee, Cheryl Zi Jin Phua, Ju Yuan, Bin Zhang, May Yin Lee, Srinivasaraghavan Kannan, Yui Hei Jasper Chiu, Casslynn W.Q. Koh, Choon Kong Yap, Edwin Kok Hao Lim et al. · 2024 · Genome Medicine
- Aberrant cytoplasmic expression of UHRF1 restrains the MHC-I-mediated anti-tumor immune responseLianmei Tan, Tao Yin, Handan Xiang, Liuyang Wang, Poorva Mudgal, Junying Chen, Yi Ding, Guoping Wang, Bryan Jian Wei Lim, Yuqi Huang et al. · 2024 · Nature Communications
- Knowledge-Guided “Community Network” Analysis Reveals the Functional Modules and Candidate Targets in Non-Small-Cell Lung CancerFan Wang, Shuqing Han, Yang Ji, Wenying Yan, Guang Hu · 2021 · Cells
- Multi-omics characterization of esophageal squamous cell carcinoma identifies molecular subtypes and therapeutic targetsDengyun Zhao, Yaping Guo, Huifang Wei, Xuechao Jia, Yafei Zhi, Guiliang He, Wenna Nie, Limeng Huang, Penglei Wang, Kyle Vaughn Laster et al. · 2024 · JCI Insight
- Deciphering the dark cancer phosphoproteome using machine-learned co-regulation of phosphositesWen Jiang, Eric J. Jaehnig, Yuxing Liao, Zhiao Shi, Tomer M. Yaron, Jared Lee Johnson, Lewis C. Cantley, Bing Zhang · 2025 · Nature Communications
- Posttranslational Modification in Bone Homeostasis and OsteoporosisYuzhe Lin, Shide Jiang, Yuming Yao, Hengzhen Li, Hongfu Jin, Guang Yang, Bingzhou Ji, Yusheng Li · 2025 · MedComm
- Refining treatment strategies for non-small cell lung cancer lacking actionable mutations: insights from multi-omics studiesAndrea Rocca, Lucio Crinò, Luca Braga, F. Salton, B. Ruaro, M. Confalonieri, D. Generali, Paola Confalonieri · 2025 · British Journal of Cancer
- HSD17B6 downregulation predicts poor prognosis and drives tumor progression via activating Akt signaling pathway in lung adenocarcinomaTian Tian, Hong Yu Fu, Zhiwen Wang, Jiaru Hu, Ni Chen, Lei Lv, Qiyi Yi · 2021 · Cell Death Discovery
- A Brave New World: Virtual Reality and Augmented Reality in Systems BiologyBerk Turhan, Zeynep Hulya Gumus · 2022 · Frontiers in Bioinformatics
- A Metabolism-Related Gene Prognostic Index for Prediction of Response to Immunotherapy in Lung AdenocarcinomaBo Tang, Lanlin Hu, Tao Jiang, Yunchang Li, Huasheng Xu, Hang Zhou, Mei Lan, Ke Xu, Jun Yin, Chunxia Su et al. · 2022 · International Journal of Molecular Sciences
- Exploring the pan-cancer landscape of posttranscriptional regulationUmesh Ghoshdastider, Ataman Sendoel · 2023 · Cell Reports
- Identification of the consistently differential expressed hub mRNAs and proteins in lung adenocarcinoma and construction of the prognostic signature: a multidimensional analysisYiran Liu, Zhenyu Li, Qianyao Meng, Anhui Ning, Shenxuan Zhou, Siqi Li, Xiaobo Tao, Yutong Wu, Qiong Chen, Tian Tian et al. · 2023 · International Journal of Surgery
- Integration of proteomics in the molecular tumor boardJohanna Thiery, Matthias Fahrner · 2023 · PROTEOMICS
- A highly multiplexed quantitative phosphosite assay for biology and preclinical studiesHasmik Keshishian, E. Robert McDonald, Filip Mundt, Randy Melanson, Karsten Krug, DALE A. PORTER, Luke Wallace, Dominique Forestier, Bokang Rabasha, Sara Marlow et al. · 2021 · Molecular Systems Biology
- Epigenome signature as an immunophenotype indicator prompts durable clinical immunotherapy benefits in lung adenocarcinomaPan Xu, Caiyu Zhang, Junwei Wang, Peng Wang, Yue Gao, Shipeng Shang, Shuang Guo, Xin Li, Hui Zhi, Shangwei Ning · 2021 · Briefings in Bioinformatics
- Proteomic Stratification of Prognosis and Treatment Options for Small Cell Lung CancerZitian Huo, Yaqi Duan, Dongdong Zhan, Xizhen Xu, Nairen Zheng, Jing Cai, Ruifang Sun, Jianping Wang, Fang Cheng, Zhan Cheng Gao et al. · 2024 · Genomics Proteomics & Bioinformatics
- Obesity and survival in advanced non-small cell lung cancer patients treated with chemotherapy, immunotherapy, or chemoimmunotherapy: a multicenter cohort studyWei Nie, Jun Lü, Jie Qian, Shuyuan Wang, Lei Cheng, Zheng Liang, Guangyu Tao, Xueyan Zhang, Tianqing Chu, Baohui Han et al. · 2024 · BMC Medicine
- Comprehensive PTM profiling with SCASP-PTM uncovers mechanisms of p62 degradation and ALDOA-mediated tumor progressionZhan-Peng Lin, Guohong Gan, Xiao Xu, Chengwen Wen, Xin Ding, Xiangyu Chen, Kaijie Zhang, Wenyu Guo, Mingxin Lin, Yu-Yang Wang et al. · 2025 · Cell Reports
- Increased antioxidative defense and reduced advanced glycation end-product formation by metabolic adaptation in non-small-cell-lung-cancer patientsTamara Tomin, Sophie Elisabeth Honeder, Laura Liesinger, Daniela Gremel, Bernhard Retzl, Joerg Lindenmann, Luka Brčić, Matthias Schittmayer, Ruth Birner‐Gruenberger · 2025 · Nature Communications
- A cellular and spatial atlas of TP53-associated tissue remodeling defines a multicellular tumor ecosystem in lung adenocarcinomaWilliam Zhao, Thinh T. Nguyen, Atharva Bhagwat, Akhil Kumar, Bruno Giotti, Benjamin Kepecs, Jason L. Weirather, Navin R. Mahadevan, Åsa Segerstolpe, Komal Dolasia et al. · 2025 · Nature Cancer
- Altered expression of ACOX2 in non-small cell lung cancerJane Sze Yin Sui, Petra Martin, Anna Keogh, Pierre Murchan, Lisa Ryan, Siobhan A. Nicholson, Sinead D. Cuffe, Pilib Ó Broin, Stephen P. Finn, Gerard J. Fitzmaurice et al. · 2022 · BMC Pulmonary Medicine
- NAGS, CPS1, and SLC25A13 (Citrin) at the Crossroads of Arginine and Pyrimidines Metabolism in Tumor CellsMelissa Owusu-Ansah, Nikita Guptan, Dylon Alindogan, Michio Morizono, Ljubica Caldovic · 2023 · International Journal of Molecular Sciences
- Skeletal muscle omics signatures in cancer cachexia: perspectives and opportunitiesLinda Anne Gilmore, Traci L. Parry, Gwendolyn A. Thomas, Andy V. Khamoui · 2023 · JNCI Monographs
- Extracellular vesicles released by cancer-associated fibroblast-induced myeloid-derived suppressor cells inhibit T-cell functionCarlo P. Ramil, Handan Xiang, Peng Zhang, Aileen Cronin, Lisia Cabral, Zhizhang Yin, Josephine Hai, Huijun Wang, Benjamin Ruprecht, Yanlin Jia et al. · 2024 · OncoImmunology
- Tobacco Smoking Rewires Cell Metabolism by Inducing GAPDH Succinylation to Promote Lung Cancer ProgressionKun Wang, Jingzhuo Li, Hai Zhang, Hongyan Ma, Hong‐Yong Cui, Huai‐Qiang Ju, Jing Zhang, Qing-zhi Ma, Ming Zhao, Qing-mei Zeng et al. · 2025 · Cancer Research
- Hijacking ERAD for targeted degradation of transmembrane proteinsHaikun Song, Wei Wang, Tingfang Mei, Huiwen Zheng, Keni Ning, Xia Liu, Siulam Cheung, Zhiyuan Cao, Danqi Sheng, Xiaohan Mai et al. · 2026 · Cell
- SIMSI-Transfer: Software-Assisted Reduction of Missing Values in Phosphoproteomic and Proteomic Isobaric Labeling Data Using Tandem Mass Spectrum ClusteringFiras Hamood, Florian P Bayer, Mathias Wilhelm, Bernhard Küster, Matthew The · 2022 · Molecular & Cellular Proteomics
- Integrated Machine Learning and Bioinformatic Analyses Constructed a Network Between Mitochondrial Dysfunction and Immune Microenvironment of PeriodontitisHang Chen, Limin Peng, Zhenxiang Wang, Yujuan He, Xiaonan Zhang · 2023 · Inflammation
- PANOPLY: a cloud-based platform for automated and reproducible proteogenomic data analysisD.R. Mani, Myranda Maynard, Ramani Bhupendra Kothadia, Karsten Krug, Karen E. Christianson, David I. Heiman, Karl R. Clauser, Chet Birger, Gad A. Getz, Steven A. Carr · 2021 · Nature Methods
- Validating HMMR Expression and Its Prognostic Significance in Lung Adenocarcinoma Based on Data Mining and Bioinformatics MethodsXia Li, Haiwei Zuo, Li Zhang, Qiuwen Sun, Yong Xin, Longzhen Zhang · 2021 · Frontiers in Oncology
- Mapping the O-GlcNAc Modified Proteome: Applications for Health and DiseaseRajan A. Burt, Ibtihal M. Alghusen, Sophiya John Ephrame, M. T. Villar, A. Artigues, Chad Slawson · 2022 · Frontiers in Molecular Biosciences
- Comparative Proteomic Analysis of Glycolytic and Oxidative Muscle in PigsXiaofan Tan, Yu He, Yuqiao He, Zhiwei Yan, Jing Chen, Ruixue Zhao, Xin Sui, Lei Zhang, Xuehai Du, David M. Irwin et al. · 2023 · Genes
- Using long-read CAGE sequencing to profile cryptic-promoter-derived transcripts and their contribution to the immunopeptidomeJu Heon Maeng, H. Josh Jang, Alan Y. Du, Shin‐Cheng Tzeng, Ting Wang · 2023 · Genome Research
- Integrated proteomic and glycoproteomic analysis reveals heterogeneity and molecular signatures of brain metastases from lung adenocarcinomasYang Chun Zhao, Dainan Zhang, Bo Meng, Yong Zhang, Shunchang Ma, Jiaming Zeng, Xi Wang, Tao Peng, Xiaoyun Gong, Rui Zhai et al. · 2024 · Cancer Letters
- Exploration of the protein and pharmacological landscape of monkeypox virus treatment: from entry point to end pointCena Aram, Maryam Barancheshmeh, Ali Alishvandi, Mohammad H. Khodabandehloo, Alireza H. Shirvani, Amirhasan Fotohi, Mohammad Amin Ghezel, Amirhossein Borji, Masoud Keikha · 2025 · Molecular Diversity
- A community effort to identify and correct mislabeled samples in proteogenomic studiesSeungyeul Yoo, Zhiao Shi, Bo Wen, Soon Jye Kho, Renke Pan, Hanying Feng, Hong Chen, Anders Carlsson, Patrik Edén, Weiping Ma et al. · 2021 · Patterns
- A New Era of Integration between Multiomics and Spatio-Temporal Analysis for the Translation of EMT towards Clinical Applications in CancerAdilson Fonseca Teixeira, Siqi Wu, Rodney Brian Luwor, Hong‐Jian Zhu · 2023 · Cells
- A common druggable signature of oncogenic c-Myc, mutant KRAS and mutant p53 reveals functional redundancy and competition among oncogenes in cancerMaria Grzes, Akanksha Jaiswar, Marcin Grochowski, Weronika Wojtyś, Wojciech Kaźmierczak, Tomasz Olesiński, Małgorzata Lenarcik, Magdalena Nowak-Niezgoda, Małgorzata Kołos, Giulia Canarutto et al. · 2024 · Cell Death and Disease
- Proteogenomics offers a novel avenue in neoantigen identification for cancer immunotherapyYuqing Ren, Yi Yue, Xinyang Li, Siyuan Weng, Hui Xu, Long Liu, Quan Cheng, Peng Luo, Tengfei Zhang, Zaoqu Liu et al. · 2024 · International Immunopharmacology
- A multi-omics study links TNS3 and SEPT7 to long-term former smoking NSCLC survivalSipeng Shen, Yongyue Wei, Yi Li, Weiwei Duan, Xuesi Dong, Lijuan Lin, Dongfang You, Adonina Tardón, Chu Chen, John K. Field et al. · 2021 · npj Precision Oncology
- Transcriptome features of striated muscle aging and predictability of protein level changesHan Yu, Lauren Z. Li, Nikhitha Kastury, Cody T. Thomas, Maggie P. Y. Lam, Edward Lau · 2021 · Molecular Omics
- Comprehensive Analysis of CDK1-Associated ceRNA Network Revealing the Key Pathways LINC00460/LINC00525-Hsa-Mir-338-FAM111/ZWINT as Prognostic Biomarkers in Lung Adenocarcinoma Combined with ExperimentsWen Li, Shanshan Feng, Hao Wu, Jing Deng, Wang-Yan Zhou, Mingxi Jia, Yi Shi, Liang Ma, Xiaoxi Zeng, Zavuga Zuberi et al. · 2022 · Cells
- Proteomic analysis of brain metastatic lung adenocarcinoma reveals intertumoral heterogeneity and specific alterations associated with the timing of brain metastasesNicole Woldmar, A. Schwendenwein, Magdalena Kuras, Beáta Szeitz, Kristiina Boettiger, Anna Tisza, Viktória László, Lilla Reiniger, Attila György Bagó, Zoltán Szállási et al. · 2022 · ESMO Open
- Proteogenomic landscape of uterine leiomyomas from hereditary leiomyomatosis and renal cell cancer patientsNicholas W. Bateman, Christopher M. Tarney, Tamara S. Abulez, Anthony R. Soltis, Ming Zhou, Kelly A. Conrads, Tracy A. Litzi, Julie Oliver, Brian L. Hood, Paul H. Driggers et al. · 2021 · Scientific Reports
- BlackSheep: A Bioconductor and Bioconda Package for Differential Extreme Value AnalysisLili M. Blumenberg, Emily A. Kawaler, MacIntosh Cornwell, Shaleigh A. Smith, Kelly V. Ruggles, David Fenyö · 2021 · Journal of Proteome Research
- Proteome-based pathology: the next frontier in precision medicineMichael H. A. Roehrl, Victor B. Roehrl, Julia Y. Wang · 2020 · Expert Review of Precision Medicine and Drug Development
- Synergy of EGFR and AURKA Inhibitors in
<i>KRAS</i>
-mutated Non–small Cell Lung CancersBagnyukova, Tetyana, Egleston, Brian L., Pavlov, Valerii A., Serebriiskii, Ilya G., Golemis, Erica A., Borghaei, Hossein · 2024 · Cancer Research Communications
- Comparative analysis of integrative classification methods for multi-omics dataAlexei Novoloaca, Camilo Broc, Laurent Belœil, Wen‐Han Yu, Jérémie Becker · 2024 · Briefings in Bioinformatics
- Proteomics and EPS Compositional Analysis Reveals Desulfovibrio bisertensis SY-1 Induced Corrosion on Q235 Steel by Biofilm FormationYanan Wang, Ruiyong Zhang, Krishnamurthy Mathivanan, Yimeng Zhang, Luhua Yang, Fang Guan, Jizhou Duan · 2024 · Materials
- High-Throughput Proteomic and Phosphoproteomic Analysis of Formalin-Fixed Paraffin-Embedded TissuesMoe Haines, John R Thorup, Simone B. Gohsman, Claudia Ctortecka, Chelsea J. Newton, Daniel C. Rohrer, Galen H. Hostetter, D.R. Mani, Michael A. Gillette, Shankha Satpathy et al. · 2025 · Molecular & Cellular Proteomics
- Characterization of the extrinsic and intrinsic signatures and therapeutic vulnerability of small cell lung cancersGuizhen Wang, Zheng Wang, Shihao Bai, Yun Tan, Wen‐Zhao Zhong, Guogui Sun, Yutao Liu, Bo Pan, Chen Huang, Di Wang et al. · 2025 · Signal Transduction and Targeted Therapy
- An Interpretable Machine Learning Model for Predicting 5‐Year Survival in Breast Cancer Based on Integration of Proteomics and Clinical DataZhixuan Wu, Shengnan Yao, Lingli Jin, Xue Wu, Rongrong Zhang, Ouchen Wang, Erjie Xia · 2025 · iMetaMed
- Mastering the Complex Targeted Therapy for Non-small Cell Lung CancerSiddhartha H. K. Devarakonda, Ramaswamy Govindan, Daniel Morgensztern · 2020 · Cancer Cell
- Exploration of the Key Proteins of High-Grade Intraepithelial Neoplasia to Adenocarcinoma Sequence Using In-Depth Quantitative Proteomics AnalysisYin Zhang, Chunyuan Li, Meng Pan, Jingying Li, Wei Ge, Lai Xu, Yi Xiao · 2021 · Journal of Oncology
- Phosphoproteomic analysis of neoadjuvant breast cancer suggests that increased sensitivity to paclitaxel is driven by CDK4 and filamin ASilvana Andrea Mouron, María J. Bueno, Ana M. Lluch, Luís Manso, Isabel Calvo, Javier Cortés, José Á. García-Sáenz, Miguel Gil‐Gil, Noelia Martínez-Jáñez, Juan V. Apala et al. · 2022 · Nature Communications
- Prognostic and Immune Infiltration Value of Proteasome Assembly Chaperone (PSMG) Family Genes in Lung AdenocarcinomaDo Thi Minh Xuan, I‐Jeng Yeh, Che‐Yu Su, Hsin-Liang Liu, Hoang Dang Khoa Ta, Gangga Anuraga, Chung-Chieh Chiao, Chih‐Yang Wang, Meng‐Chi Yen · 2022 · International Journal of Medical Sciences
- Dichloroacetophenone biphenylsulfone ethers as anticancer pyruvate dehydrogenase kinase inhibitors in non-small cell lung cancer modelsYizhen Guo, Yan Zhou, Puhua Wu, Maoxin Ran, Ngai Xu, Wenying Shan, Ou Sha, Kin Yip Tam · 2023 · Chemico-Biological Interactions
- Proteogenomic Characterization Reveals Estrogen Signaling as a Target for Never-Smoker Lung Adenocarcinoma Patients without EGFR or ALK AlterationsSeung‐Jin Park, Shinyeong Ju, Sung‐Ho Goh, Byoung-Ha Yoon, Jong‐Lyul Park, Jeong‐Hwan Kim, Seonjeong Lee, Sang-Jin Lee, Yu Mi Kwon, Wonyeop Lee et al. · 2024 · Cancer Research
- Extracellular Matrix Sulfation in the Tumor Microenvironment Stimulates Cancer Stemness and InvasivenessAlican Kuşoğlu, Deniz Örnek, Aslı Dansık, Ceren Uzun, Sena Nur Özkan, Sevgi Sarıca, Kardelen Yangın, Şevval Özdinç, Duygu Turan Sorhun, Nuriye Solcan et al. · 2024 · Advanced Science
- Current Immunotherapeutic Strategies Targeting the PD-1/PD-L1 Axis in Non-Small Cell Lung Cancer with Oncogenic Driver MutationsIchidai Tanaka, Masahiro Morise · 2021 · International Journal of Molecular Sciences
- Curcumin: A potential therapeutic natural product for adenocarcinomasMahshid Moballegh Nasery, Mohammad Varzandeh, Saghar Pahlavanneshan, Neda Mohamadi, Solmaz Sarhadi, Hojjat Samareh Fekri, Reza Mohammadinejad, Kwang Seok Ahn · 2022 · Phytochemistry Letters
- Deep Learning and Its Applications in Computational PathologyHong, Runyu, Fenyö, David · 2022 · BioMedInformatics
- In Situ MXene-Controlled Synthesis of Polycrystalline TiO2 for Highly Efficient Enrichment of PhosphopeptidesFeifei Xu, Danyi Shang, Congcong Zhu, Gaohui Du, Jingchen Shi, Xuefang Dong, Xiuling Li, Xinmiao Liang · 2024 · ACS Applied Materials & Interfaces
- Cancer biomarkers discovered using pan-cancer plasma proteomic profilingLin Bai, Jiacheng Lyu, Jinwen Feng, Xiaoqiang Qiao, Yuanyuan Qu, Guojian Yang, Yuanxue Zhu, Lingxiao Liao, Hui Yuan Gao, Aimin Zang et al. · 2025 · Nature Biomedical Engineering
- Elucidating cellular origins and TME dynamic evolution in NSCLC through multi-omics technologiesNing Ning Chao, Li Zhang · 2025 · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
- Statistical Detection of Differentially Abundant Proteins in Experiments with Repeated Measures Designs and Isobaric LabelingTing C. Huang, Mateusz Staniak, Felipe da Veiga Leprevost, Amanda M. Figueroa‐Navedo, Alexander R. Ivanov, Alexey I. Nesvizhskii, Meena Choi, Olga Vitek A · 2023 · Journal of Proteome Research
- Microdissection of cancer-associated fibroblast infiltration subtypes unveils the secreted SERPINE2 contributing to immunosuppressive microenvironment and immuotherapeutic resistance in gastric cancer: A large-scale study integrating bulk and single-cell transcriptome profilingDong Zhang, Rui Sun, C. Di, Lin Li, Faming Zhao, Yu Han, Wenjie Zhang · 2023 · Computers in Biology and Medicine
- Tailoring pretext tasks to improve self-supervised learning in histopathologic subtype classification of lung adenocarcinomasRuiwen Ding, Anil Yadav, Erika F. Rodriguez, Ana Cristina Araújo Lemos da Silva, William W.Y. Hsu · 2023 · Computers in Biology and Medicine
- Cancer-Associated Endocrine Cells Participate in Pancreatic CarcinogenesisYuan Chen, Xinpeng Yin, Ruiyuan Xu, Rexiati Ruze, Jianlu Song, Chenxue Yin, Chenglin Hu, Chengcheng Wang, Qiang Xu, Zhao Yupei · 2024 · Gastroenterology
- ERO1A levels are a prognostic indicator in EGFR mutated non small cell lung cancerMaria A. Voronkova, B. Johnson, Nishant S. Gandhi, J. M. Koomen, M Patrick, Santhosh Shanthi Bhupathi, V. M. Wu, Andrew Elliott, Ari M. Vanderwalde, Balázs Halmos et al. · 2024 · npj Precision Oncology
- Integrated Proteomics-Based Physical and Functional Mapping of AXL Kinase Signaling Pathways and Inhibitors Define Its Role in Cell MigrationAnurima Majumder, Sina Hosseinian, Mia Stroud, Emma Adhikari, James Joseph Saller, Matthew A. Smith, Guolin Zhang, Shruti Agarwal, Marc Creixell, Benjamin S. Meyer et al. · 2022 · Molecular Cancer Research
- Genomic Landscape, Clinical Features and Outcomes of Non-Small Cell Lung Cancer Patients Harboring BRAF Alterations of Distinct Functional ClassesAlessandro Di Federico, Andrea De Giglio, Francesco Gelsomino, Dario de Biase, Francesca Giunchi, Arianna Palladini, Francesca Sperandi, Barbara Melotti, Andrea Ardizzoni · 2022 · Cancers
- MiRNA-144–5p down-modulates CDCA3 to regulate proliferation and apoptosis of lung adenocarcinoma cellsJing Wan Luo, Lilong Xia, Lei Zhang, Kaixiang Zhao, Chuanchuan Li · 2022 · Mutation research. Fundamental and molecular mechanisms of mutagenesis
- Angiogenesis goes computational – The future way forward to discover new angiogenic targets?Abhishek Subramanian, Pooya Zakeri, Mira Mousa, Halima Alnaqbi, Fatima Yousif Alshamsi, Leo Bettoni, Ernesto Damiani, Habiba S. AlSafar, Yvan Saeys, Peter Carmeliet · 2022 · Computational and Structural Biotechnology Journal
- Inflammation-related citrullination of matrisome proteins in human cancerPekka Rappu, Ujjwal Suwal, Elina Siljamäki, Jyrki Heino · 2022 · Frontiers in Oncology
- Analysis of the metabolic proteome of lung adenocarcinomas by reverse-phase protein arrays (RPPA) emphasizes mitochondria as targets for therapyLaura Torresano, Fulvio Santacatterina, Sonia Domínguez-Zorita, Cristina Nuevo‐Tapioles, Alfonso Núñez-Salgado, Pau B. Esparza‐Moltó, Lucía González-Llorente, Inés Romero-Carramiñana, Cristina Núñez de Arenas, Brenda Sánchez-Garrido et al. · 2022 · Oncogenesis
- BayesDeBulk: A Flexible Bayesian Algorithm for the Deconvolution of Bulk Tumor DataFrancesca Petralia, Azra Krek, Anna Pamela Calinawan, Daniel Charytonowicz, Robert Sebra, Song Feng, Sara J.C. Gosline, Pietro Pugliese, Amanda G. Paulovich, Jacob J. Kennedy et al. · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
- Cancer genomics and bioinformatics in Latin American countries: applications, challenges, and perspectivesErika Sofia Torres-Narvaez, D. González, Juan Andrés Artunduaga-Alvarado, Oscar Ortega‐Recalde · 2025 · Frontiers in Oncology
- Harnessing multi-omics approaches to decipher tumor evolution and improve diagnosis and therapy in lung cancerYi Cheng, Ling Bai, Jiuwei Cui · 2025 · Biomarker Research
- Proteome and Transcriptome Analysis of Gonads Reveals Intersex in Gigantidas haimaensisYu Shi, Gaoyou Yao, Hua Zhang, Huixia Jia, Panpan Xiong, Maoxian He · 2022 · BMC Genomics
- Differences in p38-STAT3-S100A11 signaling after the administration of aristolochic acid I and IVa may account for the disparity in their nephrotoxicityZhong Xian, Jingzhuo Tian, Yong Zhao, Yi Yan, Chunying Li, Jiayin Han, Yushi Zhang, Yuan Wang, Lianmei Wang, Suyan Liu et al. · 2023 · Phytomedicine
- POLRMT over‐expression is linked to WNT /beta‐catenin signaling, immune infiltration, and unfavorable outcomes in lung adenocarcinoma patientsYongkang Huang, Yajuan Qian, Yufei Xing, Yongjian Pei, Beilei Zhang, Ting Li, Xue Pan, Anyuan Zhong, Juan Du, Tong Zhou et al. · 2023 · Cancer Medicine
- Metabolic barriers in non-small cell lung cancer with LKB1 and/or KEAP1 mutations for immunotherapeutic strategiesIchidai Tanaka, Junji Koyama, Hideyuki Itoigawa, Shunsaku Hayai, Masahiro Morise · 2023 · Frontiers in Oncology
- Plasma Proteomic Signature Predicts Myeloid Neoplasm RiskDuc Tran, J. Scott Beeler, Jie Liu, Brian J. Wiley, Irenaeus C.C. Chan, Zilan Xin, Michael H. Kramer, Armel Landry Batchi-Bouyou, Xiaoyu Zong, Matthew J. Walter et al. · 2024 · Clinical Cancer Research
- Proteomics appending a complementary dimension to precision oncotherapyZhaokai Zhou, Ruiqi Zhang, Aoyang Zhou, Jinxiang Lv, Shuang Chen, Haijiao Zou, Ge Zhang, Ting Lin, Zhan Wang, Yuyuan Zhang et al. · 2024 · Computational and Structural Biotechnology Journal
- Pan‐cancer proteogenomic landscape of whole‐genome doubling reveals putative therapeutic targets in various cancer typesEunhyong Chang, Su‐Jung Kim, Hee Sang Hwang, Kyu Jin Song, Kwoneel Kim, Min‐Sik Kim, Se Jin Jang, Sungyong You, Kwang Pyo Kim, Joon‐Yong An · 2024 · Clinical and Translational Medicine
- Combination of transcriptomic and proteomic approaches helps unravel the mechanisms of luteolin in inducing liver cancer cell death via targeting AKT1 and SRCJunxia Ma, Jinggang Mo, Yifu Feng, Liezhi Wang, Hao Jiang, Junmin Li, Chong Jin · 2024 · Frontiers in Pharmacology
- Proteogenomic analysis of air-pollution-associated lung cancer reveals prevention and therapeutic opportunitiesHonglei Zhang, Chao Liu, Shuting Wang, Qing Wang, Feng Xu, Hua‐Wei Jiang, Xiao Li, Chao Luo, Lu Zhang, Fei Hou et al. · 2024 · eLife
- Xiaoqinglong decoction combined with Yupingfeng powder alleviates combined allergic rhinitis and asthma syndrome by regulating the JAK2-STAT1-MHC II signaling pathway to suppress B lymphocyte activationRuizhi Wang, Zhe Xiao, Xunqing Shi, Fan Ye, Junhai Chen, Min Dong, Huijun Qiu, Yana Zhang, Jianbo Shi, Min Zhou et al. · 2025 · Journal of Ethnopharmacology
- The Clinical Prediction Value of the Ubiquitination Model Reflecting the Immune Traits in LUADYinggang Che, Dongbo Jiang, Leidi Xu, Yuanjie Sun, Yingtong Wu, Yang Liu, Ning Chang, Jiangjiang Fan, Hangtian Xi, Dan Qiu et al. · 2022 · Frontiers in Immunology