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The Immunology of Multisystem Inflammatory Syndrome in Children with COVID-19
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Abstract
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is typically very mild and often asymptomatic in children. A complication is the rare multisystem inflammatory syndrome in children (MIS-C) associated with COVID-19, presenting 4-6 weeks after infection as high fever, organ dysfunction, and strongly elevated markers of inflammation. The pathogenesis is unclear but has overlapping features with Kawasaki disease suggestive of vasculitis and a likely autoimmune etiology. We apply systems-level analyses of blood immune cells, cytokines, and autoantibodies in healthy children, children with Kawasaki disease enrolled prior to COVID-19, children infected with SARS-CoV-2, and children presenting with MIS-C. We find that the inflammatory response in MIS-C differs from the cytokine storm of severe acute COVID-19, shares several features with Kawasaki disease, but also differs from this condition with respect to T cell subsets, interleukin (IL)-17A, and biomarkers associated with arterial damage. Finally, autoantibody profiling suggests multiple autoantibodies that could be involved in the pathogenesis of MIS-C.
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“MIS-C has distinct immunological features different from the two with respect to circulating cytokine profiles and composition of the T cell compartment”
From COVID-19 and the human innate immune system (2021) · cites this paper as Consiglio et al., 2020
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Cites
Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2
Love, M. I., Huber, W., & Anders, S. (2014) · Genome Biology · doi:10.1186/s13059-014-0550-8 · Cited by 95,106
Subramanian, A., Tamayo, P., Mootha, V. K., Mukherjee, S., Ebert, B. L., Gillette, M. A., Paulovich, A., Pomeroy, S. L., Golub, T. R., Lander, E. S., et al. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0506580102 · Cited by 53,625
Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China
Huang, C., Wang, Y., Li, X., Ren, L., Zhao, J., Hu, Y., Zhang, L., Fan, G., Xu, J., Gu, X., et al. (2020) · The Lancet · doi:10.1016/s0140-6736(20)30183-5 · Cited by 48,884
Self-citationlimma powers differential expression analyses for RNA-sequencing and microarray studies
Ritchie, M. E., Phipson, B., Wu, D., Hu, Y., Law, C. W., Shi, W., & Smyth, G. K. (2015) · Nucleic Acids Research · doi:10.1093/nar/gkv007 · Cited by 40,458
clusterProfiler: an R Package for Comparing Biological Themes Among Gene Clusters
Yu, G., Wang, L.-G., Han, Y., & He, Q.-Y. (2012) · OMICS: A Journal of Integrative Biology · doi:10.1089/omi.2011.0118 · Cited by 36,259
Tissue-based map of the human proteome
Uhlén, M., Fagerberg, L., Hallström, B. M., Lindskog, C., Oksvold, P., Mardinoglu, A., Sivertsson, Å., Kampf, C., Sjöstedt, E., Asplund, A., et al. (2015) · Science · doi:10.1126/science.1260419 · Cited by 15,286
Multisystem Inflammatory Syndrome in U.S. Children and Adolescents
Feldstein, L. R., Rose, E. B., Horwitz, S. M., Collins, J. P., Newhams, M. M., Son, M. B. F., Newburger, J. W., Kleinman, L. C., Heidemann, S. M., Martin, A., et al. (2020) · New England Journal of Medicine · doi:10.1056/nejmoa2021680 · Cited by 2,691
Hyperinflammatory shock in children during COVID-19 pandemic
Riphagen, S. D., Gomez, X., González-Martínez, C., Wilkinson, N. M., & Theocharis, P. (2020) · The Lancet · doi:10.1016/s0140-6736(20)31094-1 · Cited by 2,492
Verdoni, L., Mazza, A., Gervasoni, A., Martelli, L., Ruggeri, M., Ciuffreda, M., Bonanomi, E., & D’Antiga, L. (2020) · The Lancet · doi:10.1016/s0140-6736(20)31103-x · Cited by 2,426
SARS-CoV-2 Infection in Children
Lü, X., Zhang, L., Du, H. N., Zhang, J., Li, Y. Y., Qu, J., Zhang, W., Wang, Y., Bao, S., Li, Y., et al. (2020) · New England Journal of Medicine · doi:10.1056/nejmc2005073 · Cited by 2,423
Flagged first, then by citations
Research works printed but not linked: 2
- Anft, 2020, COVID-19 progression is potentially driven by T cell immunopathogenesis, medRxiv
- Moraleda, 2020, Multi-Inflammatory Syndrome in Children related to SARS-CoV-2 in Spain, Clin. Infect. Dis.
Cited by
Sorted by citations
Items 801–900 of 917
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da Silva, E., & Santos, R. L. (2023) · doi:10.22533/at.ed.939232505
Maqsood, M. (2023) · International Journal of Advances in Medicine · doi:10.18203/2349-3933.ijam20231459
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Fernandes, L. J., Araújo, L. C. N., de Aguiar, C., de Sousa, S. J., Martins, C., Whitaker, M. C. O., de Camargo, C. L., de Oliveira, N. S., Costa, G. S. R., Gonçalves, M. T., et al. (2023) · doi:10.22533/at.ed.9392325054
Cardoso, F. M., de Almeida, C. F., Benedito, J. G., de Almeida, I. S., Depret, D. G., Quites, B. F., Nunes, Y. D. R., de Moraes, D., de Carvalho, L. Q., Duarte, M. A., et al. (2023) · doi:10.22533/at.ed.93923250511
Barroso-Santos, J., Robledo-Martínez, A. I., Espinosa‐Padilla, S. E., Angel, R., Arteaga-García, F., Langarica-Bulos, M., Madrid-Gómez-Tagle, J. A., Sánchez-Reyes, B. A., Hernández-Cadena, S. E., Suárez-Soto, J. I., et al. (2023) · Pediatric Reports · doi:10.3390/pediatric15020030
Valdivia-Tapia, M. D. C., Vargas-Vega, A. M., Ramirez-Cortez, G., & Carreazo, N. Y. (2022) · Revista del Cuerpo Médico Hospital Nacional Almanzor Aguinaga Asenjo · doi:10.35434/rcmhnaaa.2022.154.1624
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Upadhyay, S., & Devkota, S. (2023) · Annals of Medicine and Surgery · doi:10.1097/ms9.0000000000001178
Camerini, D., Arrieta, A. C., Randall, A. Z., Gach, J. S., Maecker, H. T., Hoang, J., Imfeld, K. L., Osborne, S., Enriquez, C., Hung, C., et al. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.08.28.555120
(2021) · Pediatric Pulmonology · doi:10.1002/ppul.25497
Sözeri, B. (2023) · Ümraniye Pediatri Dergisi - Journal of Umraniye Pediatrics · doi:10.14744/upd.2023.03511
Cárdenas, P. M. C., & Toledo, A. R. (2023) · Revista Ecuatoriana de Pediatría · doi:10.52011/220
Uygun, H., Yavuz, S., Şahin, T., Erdem, N., & Turğut, M. (2023) · Journal of Pediatric Infectious Diseases · doi:10.1055/s-0043-1774781
Mentor, G., Farrar, D. S., Chiara, C. D., Dufour, M. K., Valois, S., Taillefer, S., Drouin, O., Renaud, C., & Kakkar, F. (2023) · Research Square · doi:10.21203/rs.3.rs-3356347/v1
Konstantinovа, Y. E., Vilnits, A. A., Бехтерева, М. К., Alekseeva, L. A., Glotov, O. S., & Егорова, Е. С. (2023) · Medicine of Extreme Situations · doi:10.47183/mes.2023.040
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Scatolão, L. S. (2023) · Uniedusul Editora eBooks · doi:10.51324/54180429.8
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[Multisystem inflammatory syndrome in children in the context of coronavirus disease 2019 pandemic].
Zhou, B., Huang, Y.-K., Hong, S.-X., Jiao, F., & Xie, K.-S. (2024) · PubMed Central · doi:10.7499/j.issn.1008-8830.2306093
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Al‐Antary, E. T., Arar, R., Persaud, Y., Fathalla, B. M., Rajpurkar, M., & Bhambhani, K. J. (2024) · doi:10.22541/au.170667471.10889406/v1
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Schöbi, N., Sanchez, C., Atkinson, A., Andre, M. C., Rohner, G. B., Perez, M., Trück, J., Welzel, T., Schlapbach, L. J., Bielicki, J. A., et al. (2024) · Intensive Care Medicine – Paediatric and Neonatal · doi:10.1007/s44253-024-00057-y
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COVID-19 ԸՆԹԱՑՔԻ ԱՌԱՆՁՆԱՀԱՏԿՈՒԹՅՈՒՆՆԵՐԸ ԵՐԵԽԱՆԵՐԻ ՏԱՐԲԵՐ ՏԱՐԻՔԱՅԻՆ ԽՄԲԵՐՈՒՄ (ԳՐԱԿԱՆՈՒԹՅԱՆ ԱԿՆԱՐԿ)
Ա.Գ., Կ. (2025) · MEDICINE SCIENCE AND EDUCATION · doi:10.56936/18291775-2025.40-29
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Acevedo, L., Piñeres-Olave, B. E., Niño-Serna, L. F., Vega, L. M., Gómez, I., Chacón, S., Jaramillo-Bustamante, J. C., Mulett-Hoyos, H., González-Pardo, O., Zemanate, E., et al. (2021) · Figshare · doi:10.6084/m9.figshare.17047026
Santos-Rebouças, C. B., Piergiorge, R. M., Ferreira, C. D. S., Seixas Zeitel, R. D., Gerber, A. L., Rodrigues, M. C. F., Guimarães, A. P. D. C., Silva, R. M., Fonseca, A. R., Souza, R. C., et al. (2023) · Figshare · doi:10.6084/m9.figshare.22608310
Santos-Rebouças, C. B., Piergiorge, R. M., Ferreira, C. D. S., Seixas Zeitel, R. D., Gerber, A. L., Rodrigues, M. C. F., Guimarães, A. P. D. C., Silva, R. M., Fonseca, A. R., Souza, R. C., et al. (2023) · Figshare · doi:10.6084/m9.figshare.22608307
Santos-Rebouças, C. B., Piergiorge, R. M., Ferreira, C. D. S., Seixas Zeitel, R. D., Gerber, A. L., Rodrigues, M. C. F., Guimarães, A. P. D. C., Silva, R. M., Fonseca, A. R., Souza, R. C., et al. (2023) · Figshare · doi:10.6084/m9.figshare.22608319
Santos-Rebouças, C. B., Piergiorge, R. M., Ferreira, C. D. S., Seixas Zeitel, R. D., Gerber, A. L., Rodrigues, M. C. F., Guimarães, A. P. D. C., Silva, R. M., Fonseca, A. R., Souza, R. C., et al. (2023) · Figshare · doi:10.6084/m9.figshare.22608304
Namale, P. E., Boloko, L., Vermeulen, M., Haigh, K. A., Bagula, F., Maseko, A., Sossen, B., Lee-Jones, S., Msomi, Y., McIlleron, H., et al. (2024) · London School of Economics and Political Science Theses Online (London School of Economics and Political Science) · doi:10.6084/m9.figshare.25779268
Patel, M. A., Fraser, D. D., Daley, M., Cepinskas, G., Veraldi, N., & Grazioli, S. (2024) · Figshare · doi:10.6084/m9.figshare.25632943
Qu, H., Sundberg, E., Aulin, C., Neog, M. K., Palmblad, K., Horne, A. C., Granath, F., Ek, A., Melén, E., Olsson, M., et al. (2021) · Figshare · doi:10.6084/m9.figshare.17701610
Castaldo, A., D’Anna, C., Gelzo, M., Giannattasio, A., Maglione, M., Muzzica, S., Raia, M., Scalia, G., Tripodi, L., Castaldo, G., et al. (2022) · Figshare · doi:10.6084/m9.figshare.20933437
Wolff, N., & Koutroulis, I. (2026) · Pediatric Research · doi:10.1038/s41390-025-04745-z
Gastrointestinal Symptoms in Kawasaki Disease and Multisystem Inflammatory Syndrome in Children
Fabi, M., Harahsheh, A. S., Raghuveer, G., Wehrmann, M. A., Portman, M. A., Dahdah, N., Sabati, A. A., Misra, N., Yamazaki‐Nakashimada, M. A., Khoury, M., et al. (2026) · Pediatric Cardiology · doi:10.1007/s00246-025-04097-9
Mahato, S., Naganur, S., Chauhan, N., Suthar, R., Nallasamy, K., & Angurana, S. K. (2026) · The Pediatric Infectious Disease Journal · doi:10.1097/inf.0000000000005357
Predicting recalcitrant hyperinflammatory disease course in children with Kawasaki disease and MIS-C
Şatırer, Ö., Eroğlu, F. K., Nordmeyer, J., Kumpf, M., Neunhoeffer, F., Icheva, V., Reiser, C., Buzoianu, O., Benseler, S. M., & Kuemmerle-Deschner, J. B. (2026) · Pediatric Rheumatology · doi:10.1186/s12969-026-01206-7
Amorim, G. C., da Costa, H. H. M., GOMES, C. H., Francisco, M. T., Bernedo‐Navarro, R. A., Sartorio, A. P., Pandey, R. P., Lindoso, J. Â. L., & Prudêncio, C. R. (2026) · Journal of Microbiological Methods · doi:10.1016/j.mimet.2026.107484
Randolph, H. E., Richardson, A., Buta, S., Samuels, J. G., Brodsky, N. N., Kim‐Schulze, S., Lucas, C. L., Trachtman, R. A., & Bogunovic, D. (2026) · medRxiv · doi:10.64898/2026.04.03.26350001
Dissecting human population variation in single-cell responses to SARS-CoV-2
Aquino, Y. (2023) · theses.fr (ABES) · doi:10.70675/061da45czf5e5z482dzb71dz92b95c997a05
Toczyłowski, K., Lewandowski, D., Martonik, D., & Sulik, A. (2026) · Research Square · doi:10.21203/rs.3.rs-7754190/v1
Overview of T-cell subsets and related cytokines in Kawasaki disease
Zhu, Y., & Xi, S. (2026) · Pediatric Research · doi:10.1038/s41390-026-04990-w
Kurt, Z. K., Torun, Y. T., Ibrahimkhanlı, L., & Ünal, K. (2026) · Journal of Neural Transmission · doi:10.1007/s00702-026-03162-8
Metadata
- Authors
- Consiglio, C. R., Cotugno, N., Sardh, F., Pou, C., Amodio, D., Rodriguez, L., Tan, Z., Zicari, S., Ruggiero, A., Pascucci, G. R., Santilli, V., Campbell, T., Bryceson, Y., Eriksson, D., Wang, J., Marchesi, A., Lakshmikanth, T., Campana, A., Villani, A., Rossi, P., Landegren, N., Palma, P., & Brodin, P.
- Affiliations
- Science for Life Laboratory (SE)
- University of Rome Tor Vergata (IT)
- Karolinska University Hospital (SE)
- Bambino Gesù Children's Hospital (IT)
- Karolinska Institutet (SE)
- Uppsala University (SE)
- Corresponding author
- Rossi, Paolo
- Landegren, Nils
- Brodin, Petter
- ORCID
- Consiglio, Camila Rosat
- Cotugno, Nicola
- Pou, Christian
- Amodio, Donato
- Rodriguez, Lucie
- Tan, Ziyang
- Zicari, Sonia
- Ruggiero, Alessandra
- Pascucci, Giuseppe Rubens
- Santilli, Veronica
- Campbell, Tessa
- Bryceson, Yenan
- Eriksson, Daniel
- Wang, Jun
- Marchesi, Alessandra
- Lakshmikanth, Tadepally
- Campana, Andrea
- Villani, Alberto
- Rossi, Paolo
- Landegren, Nils
- Palma, Paolo
- Brodin, Petter
- Venue
- Cell
- Publisher
- Elsevier BV
- Published
- 2020-11
- Volume
- 183
- Issue
- 4
- Pages
- 968-981.e7
- ISSN
- 0092-8674 (ISSN-L)
- PMC
- PMC7474869
- OpenAlex
- W3083424448
- Cited by
- 919
- References
- 58
- Citations by year
- 2026: 30 · 2025: 46 · 2024: 89 · 2023: 185 · 2022: 218 · 2021: 311 · 2020: 36
- FWCI
- 171.26
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Cell (publishedVersion, cc-by)
- medRxiv (acceptedVersion, cc-by-nc-nd)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Cineca Institutional Research Information System (Tor Vergata University) (submittedVersion, cc-by)
- Uppsala University Publications (Uppsala University) (submittedVersion, other-oa)
- Funders
- Knut och Alice Wallenbergs Stiftelse
- Topics
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Kawasaki Disease and Coronary Complications
- Health Sciences › Medicine › Infectious Diseases › COVID-19 Clinical Research Studies
- Health Sciences › Medicine › Hematology › Autoimmune and Inflammatory Disorders Research
- Keywords
- multisystem inflammatory syndrome in children, COVID-19 pandemic, SARS-CoV-2, Kawasaki disease, vasculitis, autoimmunity, cytokine storm, T cell subsets, IL-17A, autoantibodies, pediatric immunology, blood immune cells
- MeSH terms
- Betacoronavirus, COVID-19, SARS-CoV-2, Autoantibodies, Child, Child, Preschool, Female, Humans, Infant, Male, Mucocutaneous Lymph Node Syndrome, Pneumonia, Viral, Severity of Illness Index, T-Lymphocyte Subsets, Cytokines, Coronavirus Infections, Systemic Inflammatory Response Syndrome, Proteome, Principal Component Analysis, Immunity, Humoral, Pandemics
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