The DOI matches its Crossref record; 56 of the 56 references it cites were found in a registry or an index.
Whitefly hijacks a plant detoxification gene that neutralizes plant toxins
Open accessAbstract
Plants protect themselves with a vast array of toxic secondary metabolites, yet most plants serve as food for insects. The evolutionary processes that allow herbivorous insects to resist plant defenses remain largely unknown. The whitefly Bemisia tabaci is a cosmopolitan, highly polyphagous agricultural pest that vectors several serious plant pathogenic viruses and is an excellent model to probe the molecular mechanisms involved in overcoming plant defenses. Here, we show that, through an exceptional horizontal gene transfer event, the whitefly has acquired the plant-derived phenolic glucoside malonyltransferase gene BtPMaT1. This gene enables whiteflies to neutralize phenolic glucosides. This was confirmed by genetically transforming tomato plants to produce small interfering RNAs that silence BtPMaT1, thus impairing the whiteflies' detoxification ability. These findings reveal an evolutionary scenario whereby herbivores harness the genetic toolkit of their host plants to develop resistance to plant defenses and how this can be exploited for crop protection.
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Metadata
- Authors
- Xia, J., Guo, Z., Yang, Z., Han, H., Wang, S., Xu, H., Yang, X., Yang, F., Wu, Q., Xie, W., Zhou, X., Dermauw, W., Turlings, T. C. J., & Zhang, Y.
- Venue
- Cell
- Publisher
- Elsevier BV
- Published
- 2021-04
- Volume
- 184
- Issue
- 7
- Pages
- 1693-1705.e17
- ISSN
- 0092-8674 (ISSN-L)
- OpenAlex
- W3139030413
- Cited by
- 298
- References
- 56
- FWCI
- 33.22
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Xia, J., Guo, Z., Yang, Z., Han, H., Wang, S., Xu, H., Yang, X., Yang, F., Wu, Q., Xie, W., Zhou, X., Dermauw, W., Turlings, T. C. J., & Zhang, Y. (2021). Whitefly hijacks a plant detoxification gene that neutralizes plant toxins. Cell. https://doi.org/10.1016/j.cell.2021.02.014
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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