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InterProScan 5: genome-scale protein function classification

Open access
Jones, Philip, Binns, David, Chang, Hsin-Yu, Fraser, Matthew, Li, Weizhong, McAnulla, Craig, McWilliam, Hamish, Maslen, John, Mitchell, Alex, Nuka, Gift, Pesseat, Sebastien, Quinn, Antony F., Sangrador-Vegas, Amaia, Scheremetjew, Maxim, Yong, Siew-Yit, Lopez, Rodrigo, Hunter, Sarah·2014·Bioinformatics

Abstract

Motivation: Robust large-scale sequence analysis is a major challenge in modern genomic science, where biologists are frequently trying to characterize many millions of sequences. Here, we describe a new Java-based architecture for the widely used protein function prediction software package InterProScan. Developments include improvements and additions to the outputs of the software and the complete reimplementation of the software framework, resulting in a flexible and stable system that is able to use both multiprocessor machines and/or conventional clusters to achieve scalable distributed data analysis. InterProScan is freely available for download from the EMBl-EBI FTP site and the open source code is hosted at Google Code. Availability and implementation: InterProScan is distributed via FTP at ftp://ftp.ebi.ac.uk/pub/software/unix/iprscan/5/ and the source code is available from http://code.google.com/p/interproscan/. Contact: http://www.ebi.ac.uk/support or interhelp@ebi.ac.uk or mitchell@ebi.ac.uk

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Research works printed but not linked: 23

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Metadata

Authors
Jones, P., Binns, D., Chang, H.-Y., Fraser, M., Li, W., McAnulla, C., McWilliam, H., Maslen, J., Mitchell, A., Nuka, G., Pesseat, S., Quinn, A. F., Sangrador-Vegas, A., Scheremetjew, M., Yong, S.-Y., Lopez, R., & Hunter, S.
Venue
Bioinformatics
Published
2014-01-29
Volume
30
Issue
9
Pages
1236-1240
ISSN
  • 1367-4803 (ISSN-L)
  • 1367-4811
OpenAlex
W2101291993
Cited by
9,301
References
3
FWCI
111.46
Type
journal article
Language
en
Open access
hybrid

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CoChat. (2026). Citation check: InterProScan 5: genome-scale protein function classification. https://app.cochat.ai/papers/10.1093/bioinformatics/btu031
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Jones, P., Binns, D., Chang, H.-Y., Fraser, M., Li, W., McAnulla, C., McWilliam, H., Maslen, J., Mitchell, A., Nuka, G., Pesseat, S., Quinn, A. F., Sangrador-Vegas, A., Scheremetjew, M., Yong, S.-Y., Lopez, R., & Hunter, S. (2014). InterProScan 5: genome-scale protein function classification. Bioinformatics. https://doi.org/10.1093/bioinformatics/btu031

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