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Cited by 826

The DOI matches its Crossref record; 87 of the 87 references it cites were found in a registry or an index.

Nitric oxide signaling in health and disease

Open access
Lundberg, Jon O., Weitzberg, Eddie·2022·Cell

Abstract

The surprising discovery that the diatomic gas nitric oxide (NO) is generated by mammalian cells and serves to regulate a multitude of physiological processes has continued to fascinate biologists for almost four decades. The biochemistry of NO is complex, and novel insights into the control of NO biosynthesis and mechanisms of signal transduction are continuously emerging. NO is a key regulator of cardiovascular function, metabolism, neurotransmission, immunity, and more, and aberrant NO signaling is a central feature of many major disorders including cardiovascular disease, diabetes, and cancer. Here, we discuss the basics of NO biology emphasizing recent advances in the field including novel means of increasing NO bioactivity with therapeutic and nutritional implications.

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Crossref · 10.1016/j.cell.2022.06.010

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Metadata

Authors
Lundberg, J. O., & Weitzberg, E.
Venue
Cell
Publisher
Elsevier BV
Published
2022-08
Volume
185
Issue
16
Pages
2853-2878
ISSN
0092-8674 (ISSN-L)
OpenAlex
W4289890883
Cited by
826
References
87
FWCI
83.03
Type
journal article
Language
en
Open access
hybrid

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CoChat. (2026). Citation check: Nitric oxide signaling in health and disease. https://app.cochat.ai/papers/10.1016/j.cell.2022.06.010
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Lundberg, J. O., & Weitzberg, E. (2022). Nitric oxide signaling in health and disease. Cell. https://doi.org/10.1016/j.cell.2022.06.010

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.