The DOI matches its Crossref record; 132 of the 133 references it cites were found in a registry or an index.
Signal transduction of bone morphogenetic protein receptors
Abstract
Bone morphogenetic proteins (BMPs) play a crucial role during all stages of embryonic development. Although only two major signaling pathways have been characterized (the p38 and Smad pathways), the BMP signaling is complex and includes several negative feedback mechanisms. This article reviews the current state of BMP receptor signaling and provides a summary of the crosstalk of the BMP receptor pathway with other major signaling pathways.
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“The GAA triplet-repeat expansion in the frataxin gene was shown to interfere with frataxin gene transcription (223) because of a self-associated triplex formation at long GAA:TTC repeats (sticky DNA) (22, 193, 267, 268).”
From Intracellular iron transport and storage: from molecular mechanisms to health implications (2008) · cites this paper as [223]
Citations
Cites
Massagué, J. (1998) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.67.1.753 · Cited by 7,571
Bone: Formation by Autoinduction
Urist, M. R. (1965) · Science · doi:10.1126/science.150.3698.893 · Cited by 5,529
Mechanism of activation of the TGF-β receptor
Wrana, J. L., Attisano, L., Wieser, R., Ventura, F., & Massagué, J. (1994) · Nature · doi:10.1038/370341a0 · Cited by 2,340
Identification of Smad7, a TGFβ-inducible antagonist of TGF-β signalling
Nakao, A., Afrakhte, M., Morn, A., Nakayama, T., Christian, J. L., Heuchel, R. L., Itoh, S., Kawabata, M., Heldin, N., Heldin, C., et al. (1997) · Nature · doi:10.1038/39369 · Cited by 1,796
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Growth differentiation factor-9 is required during early ovarian folliculogenesis
Dong, J., Albertini, D. F., Nishimori, K., Kumar, T. R., Lu, N., & Matzuk, M. M. (1996) · Nature · doi:10.1038/383531a0 · Cited by 1,652
Identification of a Member of the MAPKKK Family as a Potential Mediator of TGF-β Signal Transduction
Yamaguchi, T., Shirakabe, K., Shibuyà, H., Irie, K., Oishi, I., Ueno, N., Taniguchi, T., Nishida, E., & Matsumoto, K. (1995) · Science · doi:10.1126/science.270.5244.2008 · Cited by 1,344
Hayashi, H., Abdollah, S., Qiu, Y., Cai, J., Xu, Y., Grinnell, B. W., Richardson, M. A., Topper, J. N., Gimbrone, M. A., Wrana, J. L., et al. (1997) · Cell · doi:10.1016/s0092-8674(00)80303-7 · Cited by 1,322
TGF‐β receptor‐mediated signalling through Smad2, Smad3 and Smad4
Nakao, A., Imamura, T., Souchelnytskyi, S., Kawabata, M., Ishisaki, A., Oeda, E., Tamaki, K., Hanai, J., Heldin, C., Miyazono, K., et al. (1997) · The EMBO Journal · doi:10.1093/emboj/16.17.5353 · Cited by 1,071
Smad6 inhibits signalling by the TGF-β superfamily
Imamura, T., Takase, M., Nishihara, A., Oeda, E., Hanai, J., Kawabata, M., & Miyazono, K. (1997) · Nature · doi:10.1038/39355 · Cited by 1,023
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1 of the 133 references couldn’t be matched to a known paper.
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Moustakas, A., & Heldin, C.-H. (2005) · Journal of Cell Science · doi:10.1242/jcs.02554 · Cited by 958
Dorsomorphin inhibits BMP signals required for embryogenesis and iron metabolism
Yu, P. B., Hong, C. C., Sachidanandan, C., Babitt, J. L., Deng, D. Y., Hoyng, S. A., Lin, H. Y.-F., Bloch, K. D., & Peterson, R. T. (2007) · Nature Chemical Biology · doi:10.1038/nchembio.2007.54 · Cited by 1,059
Bone morphogenetic proteins: a critical review
Bragdon, B., Moseychuk, O., Saldanha, S., King, D., Julian, J., & Nohe, A. (2011) · Cellular Signalling · doi:10.1016/j.cellsig.2010.10.003 · Cited by 691
Self-citationMechanisms of Anabolic Therapies for Osteoporosis
CANALIS, E. M., Giustina, A., & Bilezikian, J. P. (2007) · New England Journal of Medicine · doi:10.1056/nejmra067395 · Cited by 675
An, J., Yang, H., Zhang, Q., Liu, C., Zhao, J., Zhang, L., & Chen, B. (2016) · Life Sciences · doi:10.1016/j.lfs.2016.01.024 · Cited by 536
Metadata
- Authors
- Nohe, A.
- Affiliations
- Western University (CA)
- Corresponding author
- Nohe, A
- ORCID
- Nohe, A
- Venue
- Cellular Signalling
- Publisher
- Elsevier BV
- Published
- 2004-03
- Volume
- 16
- Issue
- 3
- Pages
- 291-299
- ISSN
- 0898-6568 (ISSN-L)
- OpenAlex
- W2093271566
- Cited by
- 514
- References
- 133
- Citations by year
- 2026: 3 · 2025: 5 · 2024: 11 · 2023: 7 · 2022: 17 · 2021: 10 · 2020: 12 · 2019: 9 · 2018: 17 · 2017: 16 · 2016: 30 · 2015: 31 · 2014: 22 · 2013: 26 · 2012: 31
- FWCI
- 7.24
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Cellular Signalling (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › TGF-β signaling in diseases
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Developmental Biology and Gene Regulation
- Health Sciences › Medicine › Rheumatology › Heterotopic Ossification and Related Conditions
- Keywords
- bone morphogenetic proteins, BMP receptors, signal transduction, Smad signaling, p38 MAPK pathway, negative feedback regulation, signaling crosstalk, embryonic development
- MeSH terms
- Animals, Carrier Proteins, DNA-Binding Proteins, Models, Biological, Signal Transduction, Trans-Activators, Receptors, Growth Factor, Mitogen-Activated Protein Kinases, MAP Kinase Signaling System, Feedback, Physiological, p38 Mitogen-Activated Protein Kinases, Adaptor Proteins, Signal Transducing, Smad Proteins, Bone Morphogenetic Protein Receptors
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