New role of irisin in hepatocytes: The protective effect of hepatic steatosis in vitro

Park, Min-Jung, Kim, Dong-Il, Choi, Joo-Hee, Heo, Young-Ran, Park, Soo-Hyun·2015·Cellular Signalling

Cited by (170)

Items 101–170 of 170

  1. Analysis of Changes in Serum Levels and Gene Expression Profiles of Novel Adipocytokines (Omentin, Vaspin, Irisin and Visfatin) and Their Correlation with Serum C-reactive Protein Levels in Women Diagnosed with Endometriosis
    Ecem Kaya‐Sezginer, Omer Faruk Kırlangıç, Merve Didem Eşkin Tanrıverdi, Hasan Onur Topçu, Serap Gür · 2021 · Turkish Journal of Pharmaceutical Sciences
  2. Cardioprotective Effects of Exercise: The Role of Irisin and Exosome
    Yuehuan Wang, Yi Yang, Yanjuan Song · 2024 · Current Vascular Pharmacology
  3. Effects of Exercise Intervention in Subjects with Metabolic Dysfunction-Associated Steatotic Liver Disease
    Chieh Liu, Chun‐Jen Liu · 2025 · Journal of Obesity & Metabolic Syndrome
  4. The potential role of FNDC5/irisin in various liver diseases: awakening the sleeping beauties
    Xiaoyu Wang, Lihong Mao, Chaoqun Li, Yangyang Hui, Zihan Yu, Mingyu Sun, Yifan Li, Gaoyue Guo, Wanting Yang, Binxin Cui et al. · 2022 · Expert Reviews in Molecular Medicine
  5. Serum Irisin Concentrations in Severely Inflamed Patients
    Silvio Buscemi, Davide Corleo, Sonya Vasto, Carola Buscemi, Anna Maria Barile, Giuseppe Rosafio, Cristiana Randazzo, Walter Currenti, Fabio Galvano · 2020 · Hormone and Metabolic Research
  6. Polysaccharides from Cistanche deserticola Ma prevent alcoholic fatty liver disease by regulating hepatic lipid metabolism and gut microbiota in mice
    Kai Wang, Haichao Wang, Qihui Sun, Xuefang Kou, Pei Yang, Xinyuan Zhai, Yaying Li, Shangshen Yang, Xiaoming Wang · 2025 · International Immunopharmacology
  7. Irisin Attenuates Hepatic Stellate Cell Activation and Liver Fibrosis in Bile Duct Ligation Mice Model and Improves Mitochondrial Dysfunction
    Tin Pou Lai, So Young Park, Giang Thi Huong Nguyen, Phuc Nguyen Huu Pham, Seon Mee Kang, Jeana Hong, Jae‐Ho Lee, Seung‐Soon Im, Dae Hee Choi, Eun-Hee Cho · 2024 · Endocrinology and Metabolism
  8. Potential role of irisin in digestive system diseases
    Yueming Zhang, Linxian Zhao, Huan Gao, Jinghui Zhai, Yanqing Song · 2023 · Biomedicine & Pharmacotherapy
  9. Role of irisin in Chinese patients with hypothyroidism: an interventional study
    Ning Yang, Heng Zhang, Xia Gao, Miao Li, Zhi Jian Yao, Yuan Xu, Guang Wang · 2019 · Journal of International Medical Research
  10. Both high-intensity interval training and low-intensity endurance training decrease intrahepatic lipid deposits via alterations of the expression of HIF-1α, HIG2 in a murine model of non alcoholic fatty liver disease (NAFLD)
    Mohammad Hossein Bagheri, Akbar Azamian Jazi, Ebrahim Banitalebi, Fatemeh Kazeminasab, Mohammad Hossein Nasr‐Esfahani · 2020 · Science & Sports
  11. Effects of partial vascular occlusion on irisin responses to loaded muscle contractions
    Robert R. Kraemer, Allan H. Goldfarb, Greg V. Reeves, William A. Meachum, V. Daniel Castracane · 2015 · Applied Physiology, Nutrition, and Metabolism
  12. Construction of a Pichia pastoris strain efficiently secreting irisin and assessment of its bioactivity in HepG2 cells
    Xiaodan Li, Huikun Duan, Qiqi Liu, Muhammad Umar, Wenya Luo, Xingkai Yang, Jian‐Hong Zhu, Minggang Li · 2018 · International Journal of Biological Macromolecules
  13. Prophylactic role of Premna herbacea, a dietary leafy vegetable in managing hepatic steatosis via regulating AMPK/SREBP1/ACC/HMGCR signaling pathway
    Simanta Bharadwaj, Shalini Gurumayum, Pranamika Sarma, Barsha Deka, Sagar Barge, Bhaswati Kashyap, Yunus Sheikh, Prasenjit Manna, Jagat Chandra Borah, Narayan Chandra Talukdar · 2021 · Food Bioscience
  14. Maternal serum irisin levels in early and late-onset pre-eclamptic and healthy pregnancies
    Ayşegül Özel, Ebru Alıcı Davutoğlu, Asuman Akkaya Fırat, Hakan Erenel, Mehmet Fatih Karslı, Sevim Özge Korkmaz, Rıza Madazlı · 2018 · Journal of Obstetrics and Gynaecology
  15. Fasting Insulin and Alanine Amino Transferase, but not FGF21, Were Independent Parameters Related with Irisin Increment after Intensive Aerobic Exercising
    Viridiana Abigahy de la Torre-Saldaña, Miguel Ángel Gómez-Sámano, Francisco Javier Gomez-Perez, Juan Rosas-Saucedo, Andrés León‐Suárez, Mariana Grajales-Gómez, Jorge Oseguera-Moguel, Arturo Vega‐Beyhart, Daniel Cuevas Ramos · 2019 · Revista de investigaci�n Cl�nica
  16. Therapeutic role of FNDC5/irisin in attenuating liver fibrosis via inhibiting release of hepatic stellate cell-derived exosomes
    Xin Liao, Yilin Luo, Fang Gu, Wen Song, Xin Nie, Qin Yang · 2023 · Hepatology International
  17. The effect of 60 days of 6° head-down-tilt bed rest on circulating adropin, irisin, retinol binding protein-4 (RBP4) and individual metabolic responses in young, healthy males
    Kiera Ward, Edwin R. Mulder, Petra Frings‐Meuthen, Donal J. O’Gorman, Diane Cooper · 2024 · Frontiers in Physiology
  18. Deletion of PRAK Mitigates the Mitochondria Function and Suppresses Insulin Signaling in C2C12 Myoblasts Exposed to High Glucose
    Ling Zhang, Jianguo Wang, Yu Zhao, Patrycja M. Dubielecka, Gangjian Qin, Shougang Zhuang, Eugene Y. Chin, Paul Y. Liu, Ting Cun Zhao · 2021 · Frontiers in Pharmacology
  19. Role of exercise in the mechanisms ameliorating hepatic steatosis in non-alcoholic fatty liver disease
    Javier Russell‐Guzmán, L. Karachon, Tomás A. Gacitúa, Alejandro Freundlich, Carlos Poblete-Aro, Ramón Rodrigo · 2018 · Sport Sciences for Health
  20. Gamma-glutamyl carboxylated Gas6 facilitates the prophylactic effect of vitamin K in inhibiting hyperlipidemia-associated inflammatory pathophysiology via arresting MCP-1/ICAM-1 mediated monocyte-hepatocyte adhesion
    Jijnasa Bordoloi, Dibyajyoti Ozah, Thaneswar Bora, Jatin Kalita, Prasenjit Manna · 2021 · The Journal of Nutritional Biochemistry
  21. Chemical composite of indigenous whole grain scented joha rice varietal prevents type 2 diabetes in rats through ameliorating insulin sensitization by the IRS-1/AKT/PI3K signalling cascade
    Paramita Choudhury, Suman Kumar Samanta, Swarnali Bhattacharjee, Himangshu Sarma, Rajlakshmi Devi · 2022 · Food & Function
  22. Irisin promotes tilapia muscle cell growth and amino acid uptake via IGF-1 signaling
    Wenjun Deng, Mingyu Xu, Rui Dong, Yisha Yan, Quan Jiang · 2024 · Journal of Endocrinology
  23. Maternal irisin level in last trimester isolated intrauterine growth-restriction
    Esin Merve Erol Koç, Hatice Kansu-Celik, Dilek Şahın · 2020 · The Journal of Maternal-Fetal & Neonatal Medicine
  24. Increased FNDC5/IRISIN protein expression in breast cancer tissue is associated with obesity in postmenopausal women
    María Elena Tejeda, Patricia Canto, Alberto Tenorio‐Torres, Letica Orozco-Arguelles, Ramón Mauricio Coral‐Vázquez, Alejandro Zentella‐Dehesa, Marcela Leal-García, Claudia Cecilia Vega-García, Verónica Bautista‐Piña, Juan Pablo Méndez · 2021 · Journal of Clinical Pathology
  25. The Essential Role of PRAK in Preserving Cardiac Function and Insulin Resistance in High-Fat Diet-Induced Diabetes
    Jianfeng Du, Yu Zhao, Hao Wang, Ling X. Zhang, Gangjian Qin, Shougang Zhuang, Marshall E. Kadin, Yue Eugene Chin, Paul Y. Liu, Ting Cun Zhao · 2021 · International Journal of Molecular Sciences
  26. Gut-liver axis: An emerging target for exercise in obesity management
    Laura Alexia Ramos-da-Silva, Henrique Souza-Tavares, Gabriela Rodrigues Medeiros, Nathan Soares Dantas-Miranda, Gabrielle Lima-de-Figueiredo, Daiana Araújo Santana-Oliveira, Flávia Maria Silva-Veiga, Fabiane Ferreira Martins, Vanessa Souza‐Mello · 2025 · Clinics and Research in Hepatology and Gastroenterology
  27. Hepatoprotective effects of N-acetylcysteine on liver injury by irisin upregulation and oxidative stress reduction in diabetic rats
    Mehmet Mustafa Erdogan, Mehmet Ali Erdoğan, Süleyman Koç, Alper Yalçın, Ahmet Türk, Esra Akkuş Yetkin · 2023 · Egyptian Liver Journal
  28. Irisin-mediated KEAP1 degradation alleviates oxidative stress and ameliorates pancreatitis
    Nan Tang, Wendi Li, Hezhen Shang, Zhen Fan Yang, Zengyin Chen, Guangjun Shi · 2025 · Immunologic Research
  29. Serum Irisin
    Lin Tang, Bei Yu, Yongmei Liao, Siqi Long, Haoxiang Yan, Qingqing He, Changqiang Li · 2022 · Indian Journal of Dermatology
  30. The Hormone-like Myokines Irisin as Novel Biomarker for Cardiovascular Risk Stratification”,
    Alexander A. Berezin, D. P. Myrnyi, Sergii P. Myrnyi, Alexander Е. Berezin · 2021 · Pharmacophore
  31. Irisin in thyroid diseases
    Chen Qi, Jing Wang, Kang Li, Jun-Qin Luan, Jingmei Li, Ya-Ting Wang · 2024 · Clinica Chimica Acta
  32. Evaluating the Efficacy of Irisin Injection in Mimicking the Molecular Responses Induced by Endurance Exercise in Mouse Liver Tissue
    Shirin Shahabi, Fahimeh Esfarjani, Saeed Zamani, Fahimeh Zamani Rarani, Bahman Rashidi · 2024 · International Journal of Preventive Medicine
  33. Potential role of FNDC5 in exercise-induced improvement of cognitive function
    Ruobing Zhao, Xuchang Zhou, Dongxue Wang, Haifeng Tang, Guoxin Ni · 2025 · Journal of Zhejiang University SCIENCE B
  34. Irisin and its Effects on the Metabolic Diseases
    Mirza Fahad Baig, Muhammad Khalil Ahmad Khan, Mahnoor, Munazza Perveen, Muhammad Atif, Usman Younas, Sadia Sharif · 2023 · Pakistan BioMedical Journal
  35. AAV-mediated skeletal muscle specific irisin expression does not contribute to weight loss in mice
    Bernadette B. Bagon, Junhyeong Lee, Merc Emil Matienzo, Sangyi Lim, Jae-Il Park, Sohi Kang, Keon Kim, Chang-Min Lee, Changjong Moon, Dong‐Il Kim et al. · 2023 · Biochemical and Biophysical Research Communications
  36. Inflammatory Overtones of Organokines in Metabolic Syndrome and Type 2 Diabetes
    Suktara Guria, Soumyadeep Basu, Anupama Hoory, Sutapa Mukherjee, Satinath Mukhopadhyay · 2023 · Journal of the Indian Institute of Science
  37. Does irisin mediate metabolic effects of androgen deficiency? A cross-sectional study in men with chronic spinal cord injury
    Claudia Venditti, Veronica Carnicelli, Valentina Gizzi, Camilla Tonni, Daniele Tienforti, Luca Spagnolo, Giorgio Felzani, Mauro Maccarrone, Marco Giorgio Baroni, Arcangelo Barbonetti · 2024 · Spinal Cord
  38. Sustainable Solutions From Silkworms: Antheraea assamensis Helfer Oil Regulates Oxidative Stress, Lipid Metabolism, and Liver Health—Navigating Future Food Challenges
    Richa Dhakal, Anjum Dihingia, Prachurjya Dutta, Jatin Kalita · 2025 · Molecular Nutrition & Food Research
  39. Irisin inhibits adipogenic differentiation of bone marrow mesenchymal stem cells through the SIRT1/RANBP2/FTO signaling axis and protects against osteoporosis
    Junfei Chen, Jincheng Liu, Qingyang Fu, Mingyu Xu, Xu Zhai, Le Li, Wanlong Xu, Xinhui Wu, Kaidi Wang, Haipeng Si · 2026 · Cell Death Discovery
  40. Effects of Resistance Exercise and Whey Protein Supplementation on Irisin Levels in Patients with MASLD Under a Calorie-Restricted Diet
    Feng-Rui Zhang, Chae-Been Kim, Dohyun Ahn, Jinwoo Sung, Ju Hwan Oh, Hae Ri Heo, Eun‐Ah Jo, Hong-Soo Kim, Jung-Jun Park · 2026 · Nutrients
  41. Exercise as a Metabolic Therapy for MASLD: Beyond Weight Loss Toward Sustainable Exercise Strategies
    Hee‐Tae Roh, Ju Yong Bae · 2026 · Medicina
  42. The emerging role of the Hippo signaling pathway in interorgan crosstalk
    Gahyeon Song, Chaerin Lee, Eek‐hoon Jho · 2026 · FEBS Journal
  43. Sex specific effects of irisin on the skeleton
    Anika Shimonty, Lynda Faye Bonewald · 2026 · Bone Research
  44. Potential Effect of Irisin and/or Moderate Intensity Exercise on Metabolic Homeostasis in Obesity in Male Albino Rats
    Abeer A. Abozeid · 2019 · The Medical Journal of Cairo University/The Medical Journal of Cairo University
  45. Il muscolo come organo endocrino: focus su irisina
    Carla Santos de Souza Giordano, Roberta Amodei, Claudia Di Stefano · 2022 · L Endocrinologo
  46. Research Progress of Irisin in Obesity and Related Metabolic Diseases
    怡宁 张 · 2023 · Advances in Clinical Medicine
  47. Obesity-mediated insulin resistance in target tissues: role of adiponectin, fetuin-A, and irisin
    Sutapa Mukherjee, Snehasis Das, Dipanjan Chattopadhyay, Satinath Mukhopadhyay · 2024 · Elsevier eBooks
  48. Effects of Eight Weeks of Intense Aerobic Training and Cinnamon Extract on Gene Expression of SREBP-1c and LXRα in the Liver Tissue of Rats Fed with Fructose Diets
    F Mamashli, Saqqa Farajtabar Behrestaq, Babisan Askari, Atefeh Taghipour, Asra Askari · 2024 · Iṭṭilā’āt-i māhiyānah.
  49. Irisina: ruolo nell’omeostasi del glucosio
    Annalisa Natalicchio, Nicola Marrano, Francesco Giorgino · 2018 · L Endocrinologo
  50. IRISIN: A POTENTIAL PROMISING AGENT AGAINST NON-ALCOHOLIC FATTY LIVER DISEASE IN TYPE 2 DIABETIC RATS
    Hany A. Elkattawy, Wesam M. R. Ashour · 2019 · Al-Azhar Medical Journal
  51. Low serum irisin levels in newly diagnosed patients with type 2 diabetes mellitus: a meta-analysis
    I Gusti Ngurah Metta Nurcahya, Ayu Agung Pradnya Paramitha, Ida Bagus Indra Wibawa Putrawan, Dewi Catur Wulandari · 2023 · Intisari Sains Medis
  52. Both Aerobic and Resistance Exercise Ameliorate Nonalcoholic Fatty Liver Disease Even in the Absence of Weight Reduction in High-fat Diet-induced Obese Mice
    Ju Yong Bae · 2020 · Research Square
  53. Does Irisin Link Physical Exercise with Alzheimer’s Disease?
    Dewan Md. Sumsuzzman, Yunho Jin, Yonggeun Hong · 2017 · Preprints.org
  54. DJ-1 deficiency alleviates steatosis in cultured hepatocytes
    Harmesh N. Chaudhari, Jong Won Yun · 2015 · Biotechnology and Bioprocess Engineering
  55. Verbascoside, a Caffeoyl Phenylethanoid Glycoside Mediates the Prophylactic Role of Premna Herbacea, a Dietary Leafy Vegetable in Managing Hepatic Steatosis Via Regulating AMPK/SREBP1/ACC/HMGCR Signaling Pathway
    Simanta Bharadwaj, Gurumayum Shalini Devi, Pranamika Sarma, Barsha Deka, Sagar Barge, Bhaswati Kashyap, Yunus Sheikh, Prasenjit Manna, Jagat Chandra Borah, Narayan Chandra Talukdar · 2021 · SSRN Electronic Journal
  56. Study the association of circulating level of Irisin with the anthropometric and metabolic parameters in normal weight, overweight and obese children
    Laura Khalil, Osama Ezzat Botrous, Marwa Abdeltawab Mohammed, Gehad Mohamed Abo elhassan · 2022 · Egyptian Journal of Medical Research
  57. Irisina: un singolo ormone, molti cross-talk
    Annalisa Natalicchio, Nicola Marrano, Francesco Giorgino · 2023 · il Diabete
  58. The Therapeutic Effects of Different Exercise Forms on Nonalcoholic Fatty Liver Disease: A Meta-Analysis
    云辉 武 · 2023 · Advances in Clinical Medicine
  59. Identification of potent allosteric inhibitors of PRMT3: pharmacophore based 3D-QSAR modeling and molecular simulations approach
    Shoufia Jabeen Mubarak, Hemamalini Vedagiri · 2023 · Research Square
  60. Irisin in myelodysplastic syndromes: connecting inflammation, oncogenesis, and atherogenesis
    Mohamed Abdelhafez, Sabry Abd Allah Shoeib, Ayman Fathy Arafa, Ashraf Dawood, Aly Mohamed Elkholy, Shrief R. Abd Elrahman, Mahmoud Ahmed Elrefy, Ghada Hamdy Akl · 2024 · The Egyptian Journal of Haematology
  61. The Role of Skeletal Muscles in Metabolic Dysfunction-Associated Steatotic Liver Disease
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  62. Role of Myokines and prospects for their role in Diabetes Mellitus Therapy
    Kharissova Nuriya, Mindubaуeva Farida, RK Sharma, Smirnova Liliya, Xeniya E. Mkhitaryan, Chergizova B., Yelena Salikhova, Y. Niyazova, Ryspayeva G., Evnevich A. et al. · 2024 · Research Journal of Pharmacy and Technology
  63. Expression and Clinical Significance of Irisin in Serum and Placenta Tissues of Pregnant Women with Severe Preeclampsia
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  64. Combination Effect of Caffeine Intake and Thermotherapy on the Blood Levels of Human Irisin and Fibroblast Growth Factor 21 in Healthy Males
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  65. Altérations de la fonction motrice induites par une restriction sensorimotrice précoce chez le rat : implication du dialogue muscle-cerveau
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  66. Royal Jelly and 10‐Hydroxy‐2‐decenoic Acid Mitigate Alcoholic Fatty Liver Disease in Mice via the Gut‐Microbiota‐Metabolite Axis
    Lining Ren, Weiman Gao, Xinyu Ma, Haitao Zhang, Yuhang Xiao, Shijing Jiang, Guochen Liu, Aidong Sun · 2026 · Molecular Nutrition & Food Research
  67. Change in circulating irisin level and its association with lipid metabolism after exenatide treatment in patients with type 2 diabetes mellitus
    Yuting Gao, Xiaoyu Hong, Kun Yang, Yunyi Le, Rui Wei, Jin Yang, Tianpei Hong, Qing Tian · 2026 · Journal of Clinical & Translational Endocrinology
  68. Phytochemicals and Irisin as Multi-Target Regulators of Adipose Tissue Browning and Metabolic Reprogramming: Synergies with GLP-1 Pathways
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  69. Irisin promotes lipid clearance through the CD81-integrin-FAK axis in steatotic hepatocytes
    Po-Han Chen, Yu‐Chun Lin, Jian‐Han Chen, Po-Huang Lee, Yo-Chen Chang, Cheuk-Kwan Sun, Y. H. Kao, Ming‐Hong Tai · 2026 · Journal of Physiology and Biochemistry
  70. BindingDB Entry 50000349: Discovery of Potent and Selective Allosteric Inhibitors of Protein Arginine Methyltransferase 3 (PRMT3).
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