Protective Roles for Caspase-8 and cFLIP in Adult Homeostasis
Weinlich, Ricardo, Oberst, Andrew, Dillon, Christopher P., Janke, Laura J., Milasta, Sandra, Lukens, John R., Rodriguez, Diego A., Gurung, Prajwal +3 more·2013·Cell Reports
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- Short form FLICE-inhibitory protein promotes TNFα-induced necroptosis in fibroblasts derived from CFLARs transgenic miceRyodai Shindo, Soh Yamazaki, Masaki Ohmuraya, Kimi Araki, Hiroyasu Nakano · 2016 · Biochemical and Biophysical Research Communications
- A Risk Model Developed Based on Necroptosis Predicts Overall Survival for Hepatocellular Carcinoma and Identification of Possible Therapeutic DrugsZedong Li, Jianyu Fang, Sheng Chen, Hao Liu, Jun Zhou, Jiangsheng Huang, Sushun Liu, Yu Peng · 2022 · Frontiers in Immunology
- Anti-leukemia activity of NSC-743380 in SULT1A1-expressing acute myeloid leukemia cells is associated with inhibitions of cFLIP expression and PI3K/AKT/mTOR activitiesXiao Huang, Mengru Cao, Shuhong Wu, Li Wang, Jing Hu, Reza John Mehran, Jack A. Roth, Stephen G. Swisher, Ruiyu Wang, Hagop M. Kantarjian et al. · 2017 · Oncotarget
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- Immunologic Repercussions of Cell DeathHelen M. Beere, Douglas R. Green · 2016 · Elsevier eBooks
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- Mutation Analysis of the Dimer Forming Domain of the Caspase 8 Gene in Oral Submucous Fibrosis and Squamous Cell CarcinomasUthara Menon, V. Poongodi, Raghuram Hari Pitty, Kannan Ashokan, Giri Valandhan Vedha, Arvind Ramanathan · 2015 · Asian Pacific Journal of Cancer Prevention
- Generation and Use of Chimeric RIP Kinase Molecules to Study NecroptosisDiego A. Rodríguez, Douglas R. Green · 2018 · Methods in molecular biology
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- The effects of intrinsic apoptosis on cystogenesis in PKD1-deficient ADPKD pig modelRunming Wang, Wenya Li, Suhong Zhang, Song Ya, Haiting Dai, Tan Tan, Xiaoxiang Hu, Yiming Xing · 2021 · Gene
- NecroptosisBen A. Croker, James A. Rickard, Inbar Shlomovitz, Arshed Al‐Obeidi, Akshay A. D’Cruz, Motti Gerlic · 2018 · Wiley eBooks
- Mechanisms of Toxicant-Induced Acute Kidney InjuryLawrence Harold Lash, Brian S. Cummings · 2016 · Elsevier eBooks
- Seminars in Cell & Developmental BiologyWen Zhou, Junying Yuan · 2014
- Chicken ovalbumin upstream promoter-transcription factor II protects against cisplatin-induced acute kidney injurySumiyasu Ishii, Masanobu Yamada, Noriyuki Koibuchi · 2019 · Endocrine Journal
- Hydroxysafflor yellow A protects against ischemic stroke-associated Weber syndrome by inhibiting oxidative stress and alleviating DNA damageMiaolin Zeng, Huifen Zhou, Lian Zeng, Man zhang, Jiehong Yang, Wujun Geng, Haitong Wan · 2026 · Brain Research Bulletin
- Nuclear DAMPs in Hepatic Injury and InflammationRui Kang, Daolin Tang · 2017 · Springer eBooks
- PyroptosisKate E. Lawlor, Stephanie A. Conos, James Edward Vince · 2018 · Wiley eBooks
- Holding RIPK1 on the Ubiquitin Leash in TNFR1Signaling Peltzer, Maurice Darding, Henning Walczak · 2016
- Eliminação antígeno-específica de células-alvo caspase-8 - suficientes ou - deficientes por linfócitos T CD8>sup<+>/sup<Isabella Suzuki Sampaio · 2019 · Digital Library of Theses and Dissertations (Universidade de São Paulo)
- Modulação gênica de RIPK3 e MLKL e seu impacto na sensibilidade a morte por necroptoseLarissa Zanetti · 2021
- Peer Review #2 of "In silico analysis reveals a shared immune signature in CASP8-mutated carcinomas with varying correlations to prognosis (v0.2)"2019 · PeerJ
- Competitive Regulation of Splenic DC Subsets During Acute Infection: MCMV-induced loss occurs independently of IFN-I and can be reversed by virus-sensitive, licensed NK cellsW. A. Nash · 2016
- Peer Review #1 of "In silico analysis reveals a shared immune signature in CASP8-mutated carcinomas with varying correlations to prognosis (v0.2)"2019 · PeerJ
- Faculty Opinions recommendation of LUBAC prevents lethal dermatitis by inhibiting cell death induced by TNF, TRAIL and CD95L.Michael McDermott, Heledd Jarosz-Griffiths · 2019 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
- Peer Review #1 of "In silico analysis reveals a shared immune signature in CASP8-mutated carcinomas with varying correlations to prognosis (v0.1)"2019 · PeerJ
- Peer Review #2 of "In silico analysis reveals a shared immune signature in CASP8-mutated carcinomas with varying correlations to prognosis (v0.1)"2019 · PeerJ
- Caspase 8 protects pancreatic neoplasia from KRAS-driven necroptotic primingSofya Tishina, Alina Dahlhaus, Ariadne Androulidaki, Michael Kotliar, Lejla Mulalic, Hassan Rakhsh-Khorshid, Florian Hocher, Jenny Stroh, Julia Beck, Marta Manik et al. · 2023 · Research Square
- Oncogenic KRAS-induces necroptotic priming of pancreatic neoplasiaSofya Tishina, Alina Dahlhaus, Ariadne Androulidaki, Michael Kotliar, Lejla Mulalic, Hassan Rakhsh-Khorshid, Florian Hocher, Jenny Stroh, Julia Beck, Marta Manik et al. · 2023 · Research Square
- Novel functions of LUBAC-mediated M1 poly-ubiquitination in TNFR1-mediated necroptosisNadine Weinelt · 2024
- Cell death in acetaminophen (APAP) toxicityLayla Shojaie, Helia Alavifard, Lily Dara · 2024 · Elsevier eBooks
- Mechanisms of Toxicant-Induced Acute Kidney InjuryBrian S. Cummings · 2024 · Elsevier eBooks
- Caractérisation de nouveaux inhibiteurs de la kinase RIPK1 et de la nécroptoseFabienne Le Cann · 2017 · theses.fr (ABES)
- Mise en place et étude de modèles de progression de la NASH jusqu’au développement du CHC : effet du régime hyperlipidique sur l’environnement hépatiqueMélanie Simoes Eugénio · 2019
- Caspase-8 silences cell death-independent constitutive immune activation driven by tonic TNF-αGermana Lentini, Francesco Coppolino, Agata Famà, Giuseppe Valerio De Gaetano, Federica Grasso, Luigi Fiore, Alessia Berbiglia, Silvia Carnevale, Isabella Venza, Egil Lien et al. · 2026 · EMBO Reports
- Oncogenic KRAS-driven type I interferon signalling primes pancreatic cancer for necroptosisSofya Tishina, Alina Dahlhaus, Marta Manik, Lejla Mulalic, Janine Murr, Michael Kotliar, Hassan Rakhsh-Khorshid, Myrto Kostopoulou, Florian Hocher, Jenny Stroh et al. · 2026 · Nature Communications
- Caspases and programmed cell death in sepsis: mechanisms, pathophysiology, and therapeutic targetsHe He, 谢秀丽, Lisui Zhou, Yumeng Lin, Aijun Liu, Peng Guo, Yu Zhu, Yan Tang, Zhongyu Han, Yue Wang et al. · 2026 · Frontiers in Immunology
- Serum receptor-interacting protein kinase 3 (RIPK3) is associated with transplant-free survival in acute liver failureGautam Mehta, Chengyi Ding, Ugo Soffientini, Jaime Lynn Speiser, Sarah Bahnassi, Lily Dara, Valerie Durkalski, William M. Lee, Constantine Jason Karvellas · 2026 · JHEP Reports