Transcription Factor Cooperativity in Early Adipogenic Hotspots and Super-Enhancers
Siersbæk, Rasmus, Rabiee, Atefeh, Nielsen, Ronni, Sidoli, Simone, Traynor, Sofie, Loft, Anne, Poulsen, Lars La Cour, Rogowska-Wrzesinska, Adelina +2 more·2014·Cell Reports
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- A PPARγ/long noncoding RNA axis regulates adipose thermoneutral remodeling in miceZhengyi Zhang, Ya Cui, Vivien Su, Dan Wang, Marc J. P. M. Tol, Lijing Cheng, Xiaohui Wu, Jason Kim, Prashant Rajbhandari, Sicheng Zhang et al. · 2023 · Journal of Clinical Investigation
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- The impact of SWI/SNF and NuRD inactivation on gene expression is tightly coupled with levels of RNA polymerase II occupancy at promotersSachin Pundhir, Jinyu Su, Marta Cecylia Tapia, Anne Meldgaard Hansen, James Haile, Klaus H. Hansen, Bo Torben Porse · 2023 · Genome Research
- Spatiotemporal dynamics of SETD5-containing NCoR–HDAC3 complex determines enhancer activation for adipogenesisYoshihiro Matsumura, Ryo Ito, Ayumu Yajima, Rei Yamaguchi, Toshiya Tanaka, Takeshi Kawamura, Kenta Magoori, Yohei Abe, Aoi Uchida, Takeshi Yoneshiro et al. · 2021 · Nature Communications
- Characterization of a functional endothelial super-enhancer that regulates ADAMTS18 and angiogenesisIsidore Mushimiyimana, Henri Niskanen, Mustafa Beter, Johanna P. Laakkonen, Minna Unelma Kaikkonen, Seppo Ylä‐Herttuala, Nihay Laham-Karam · 2021 · Nucleic Acids Research
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- The Mediator subunit MED20 organizes the early adipogenic complex to promote development of adipose tissues and diet-induced obesityWen-Shuai Tang, Li Weng, Xu Wang, Changqin Liu, Guo-Sheng Hu, Shu-Ting Yin, Tao Ying, Ni-Na Hong, Huiling Guo, Wen Liu et al. · 2021 · Cell Reports
- Wnt3a disrupts GR-TEAD4-PPARγ2 positive circuits and cytoskeletal rearrangement in a β-catenin-dependent manner during early adipogenesisBongju Park, Soojeong Chang, Gwan-Jun Lee, Byeongsoo Kang, Jong Kyoung Kim, Hyunsung Park · 2019 · Cell Death and Disease
- Experimental Validation and Prediction of Super-Enhancers: Advances and ChallengesEkaterina V. Kravchuk, German A. Ashniev, Marina G. Gladkova, А. В. Орлов, Anastasiia V. Vasileva, Anna Boldyreva, Alexandr G. Burenin, Artemiy M. Skirda, Petr Ivanovich Nikitin, Natalia N. Orlova · 2023 · Cells
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- Dynamic Interactions of Transcription Factors and Enhancer Reprogramming in Cancer ProgressionEmily Kate Zboril, Hannah Yoo, Lizhen Chen, Zhijie Liu · 2021 · Frontiers in Oncology
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- Pioneer factors: Emerging rules of engagement for transcription factors on chromatinized DNAManuel Carminati, Luca Vecchia, Lisa Stoos, Nicolas H. Thomä · 2024 · Current Opinion in Structural Biology
- SNP-adjacent super enhancer network mediates enhanced osteogenic differentiation of MSCs in ankylosing spondylitisWenhui Yu, Keng Chen, Guiwen Ye, Shan Wang, Peng Wang, Jinteng Li, Zheng Guan, Wenjie Liu, Jiajie Lin, Zepeng Su et al. · 2020 · Human Molecular Genetics
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- Kinetic networks identify TWIST2 as a key regulatory node in adipogenesisArun B. Dutta, Daniel S. Lank, Róża K. Przanowska, Piotr Przanowski, Lixin Wang, Bao Nguyen, Ninad M. Walavalkar, Fabiana M. Duarte, Michael J. Guertin · 2023 · Genome Research
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- Targeting GSK ‐3β for adipose dysfunction and cardiovascular complications of metabolic disease: An entangled WNT /β‐catenin questionNasser Alotaiq, Ahmed S. Khalifa, Amr Youssef, E. Elnagar, Nasr Eldin Elwali, Hosam M. Habib, Ibrahim AlZaim, Ali Hussein Eid, Nour‐Mounira Z. Bakkar, Ahmed Fawzy EL‐Yazbi · 2024 · The FASEB Journal
- xCT-mediated glutamate excretion in white adipocytes stimulates interferon-γ production by natural killer cells in obesityHee‐Hoon Kim, Young‐Ri Shim, Ha‐Neul Kim, Keungmo Yang, Tom Ryu, Kyurae Kim, Sung Eun Choi, Minjeong Kim, Chaerin Woo, Katherine Po Sin Chung et al. · 2023 · Cell Reports
- Osteoporosis- and obesity-risk interrelationships: an epigenetic analysis of GWAS-derived SNPs at the developmental gene TBX15Xiao Zhang, Kenneth C. Ehrlich, Fangtang Yu, Xiaojun Hu, Xiang‐He Meng, Hong‐Wen Deng, Hui Shen, Melanie Ehrlich · 2020 · Epigenetics
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