ARTD1/PARP1 Negatively Regulates Glycolysis by Inhibiting Hexokinase 1 Independent of NAD+ Depletion

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3. Polyubiquitination of apurinic/apyrimidinic endonuclease 1 by Parkin
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4. DNA Repair Molecular Beacon assay: a platform for real-time functional analysis of cellular DNA repair capacity
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5. Visualizing physiological parameters in cells and tissues using genetically encoded indicators for metabolites
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6. HMGA 2 as a functional antagonist of PARP 1 inhibitors in tumor cells
   Sabine Hombach‐Klonisch, Forouh Kalantari, Manoj Reddy Medapati, Suchitra Natarajan, Sai Nivedita Krishnan, Aditya Kumar-Kanojia, Thatchawan Thanasupawat, Farhana Begum, Fred Y. Xu, Grant Michael Hatch et al. · 2018 · Molecular Oncology
7. Suppressing PARylation by 2′,5′‐oligoadenylate synthetase 1 inhibits DNA damage‐induced cell death
   Anna A. Kondratova, HyeonJoo Cheon, Beihua Dong, Elise G. Holvey-Bates, Metis Hasipek, Irina Taran, Christina Gaughan, Babal Kant Jha, Robert H. Silverman, George Robert Stark · 2020 · The EMBO Journal
8. Role of PARP-catalyzed ADP-ribosylation in the Crosstalk Between DNA Strand Breaks and Epigenetic Regulation
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9. Regulation of Cancer and Cancer-Related Genes via NAD +
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10. Functional Role of ADP-Ribosyl-Acceptor Hydrolase 3 in poly(ADPRibose) Polymerase-1 Response to Oxidative Stress
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11. The Role of PARP1 in Monocyte and Macrophage Commitment and Specification: Future Perspectives and Limitations for the Treatment of Monocyte and Macrophage Relevant Diseases with PARP Inhibitors
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12. Mitochondrial NUDIX hydrolases: A metabolic link between NAD catabolism, GTP and mitochondrial dynamics
    Aaron N Long, Nina Klimova, Tibor Kristián · 2017 · Neurochemistry International
13. Poly(adenosine diphosphate-ribose) polymerase as therapeutic target: lessons learned from its inhibitors
    Anna Maria Cseh, Zsolt Fábián, Balázs Sümegi, Luca Scorrano · 2017 · Oncotarget
14. Base Excision Repair and Nucleotide Excision Repair
    Tadahide Izumi, Isabel Mellon · 2016 · Elsevier eBooks
15. Poly(ADP-ribose) polymerase-1 inhibits mitochondrial respiration by suppressing PGC-1α activity in neurons
    Ping Lü, Adam D. Hogan-Cann, Amit Kumar Kamboj, Subir Roy Chowdhury, Mohamad‐Reza Aghanoori, Paul Fernyhough, Christopher M. Anderson · 2019 · Neuropharmacology
16. Synergistic Dual Targeting of Thioredoxin and Glutathione Systems Irrespective of p53 in Glioblastoma Stem Cells
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17. Mitochondria - Nucleus communication in neurodegenerative disease. Who talks first, who talks louder?
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18. Asthma and poly(ADP-ribose) polymerase inhibition: a new therapeutic approach
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19. Enlightening brain energy metabolism
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20. Cell death classification: A new insight based on molecular mechanisms
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21. Cul4a as a New Interaction Protein of PARP1 Inhibits Oxidative Stress-Induced H9c2 Cell Apoptosis
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22. Molecular mechanisms of cell death by parthanatos: More questions than answers
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23. TCDD-inducible poly (ADP-ribose) polymerase promotes adipogenesis of both brown and white preadipocytes
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24. Overcoming Temozolomide Resistance in Glioblastoma via Enhanced NAD+ Bioavailability and Inhibition of Poly-ADP-Ribose Glycohydrolase
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25. Exposure to fluoride exacerbates the cognitive deficit of diabetic patients living in areas with endemic fluorosis, as well as of rats with type 2 diabetes induced by streptozotocin via a mechanism that may involve excessive activation of the poly(ADP ribose) polymerase-1/P53 pathway
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26. PARP inhibitors protect against sex- and AAG-dependent alkylation-induced neural degeneration
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27. Pharmacologic inhibition of MIF nuclease: A new treatment paradigm to treat cell death
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28. CASK Mediates Oxidative Stress-Induced Microglial Apoptosis-Inducing Factor-Independent Parthanatos Cell Death via Promoting PARP-1 Hyperactivation and Mitochondrial Dysfunction
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29. Ozone Exposure Induces Metabolic Disorders and NAD+ Depletion Through PARP1 Activation in Spinal Cord Neurons
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30. ALKBH7 drives a tissue and sex-specific necrotic cell death response following alkylation-induced damage
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31. Comparing the Influence of High Doses of Different Zinc Salts on Oxidative Stress and Energy Depletion in IPEC-J2 Cells
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32. UV-DDB stimulates the activity of SMUG1 during base excision repair of 5-hydroxymethyl-2'-deoxyuridine moieties
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34. The dynamic process of covalent and non-covalent PARylation in the maintenance of genome integrity: a focus on PARP inhibitors
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35. Suppression of oxidative phosphorylation in mouse embryonic fibroblast cells deficient in apurinic/apyrimidinic endonuclease
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36. NAD + depletion is central to placental dysfunction in an inflammatory subclass of preeclampsia
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37. The Role of PARP1 and PAR in ATP-Independent Nucleosome Reorganisation during the DNA Damage Response
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38. Alkyladenine DNA glycosylase deficiency uncouples alkylation-induced strand break generation from PARP-1 activation and glycolysis inhibition
    Fahad Abdulrahman Alhumaydhi, Débora de Oliveira Lopes, Diana Lilian Bordin, Abdullah S. M. Aljohani, Cameron B. Lloyd, Michael McNicholas, Larissa Milano, Clara Forrer Charlier, Izabel Vianna Villela, João Antônio Pêgas Henriques et al. · 2020 · Scientific Reports
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40. Functional analysis of ZmG6PE reveals its role in responses to low-phosphorus stress and regulation of grain yield in maize
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41. Poly( ADP ‐ribose) mediates bioenergetic defects and redox imbalance in neurons following oxygen and glucose deprivation
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42. PARP-1 inhibitor alleviates cerebral ischemia/reperfusion injury by reducing PARylation of HK-1 and LDH in mice
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43. PARylation-mediated post-transcriptional modifications in cancer immunity and immunotherapy
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44. Live Cell Detection of Poly(ADP-Ribose) for Use in Genetic and Genotoxic Compound Screens
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45. Polβ/XRCC1 heterodimerization dictates DNA damage recognition and basal Polβ protein levels without interfering with mouse viability or fertility
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46. Cannabinoids induce cell death in leukaemic cells through Parthanatos and PARP-related metabolic disruptions
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47. Tumor-targeted nano-assemblies for energy-blocking cocktail therapy in cancer
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48. Unraveling the allosteric inhibition mechanism of PARP-1 CAT and the D766/770A mutation effects via Gaussian accelerated molecular dynamics and Markov state model
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49. Intracellular accumulation of free cholesterol in macrophages triggers a PARP1 response to DNA damage and PARP1 impairs lipopolysaccharide-induced inflammatory response
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50. Role of NAD+ and FAD in Ischemic Stroke Pathophysiology: An Epigenetic Nexus and Expanding Therapeutic Repertoire
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51. Quantitative Analysis of Nuclear Poly(ADP-Ribose) Dynamics in Response to Laser-Induced DNA Damage
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52. The CYLD–PARP1 feedback loop regulates DNA damage repair and chemosensitivity in breast cancer cells
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53. DNA polymerase beta expression in head & neck cancer modulates the poly(ADP-ribose)-mediated replication checkpoint
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54. "Yin-Yang" of PARP1 in genotoxic and inflammatory response
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55. Hypoxia-Induced Creatine Uptake Reprograms Metabolism to Antagonize PARP1-Mediated Cell Death and Facilitate Tumor Progression in Hepatocellular Carcinoma
    Rui‐Zhe Li, Guo‐Qiang Pan, Chen Xiong, Zi‐Niu Ding, Tuan-Song Zhang, Lun‐Jie Yan, Dongxu Wang, Xiaolu Zhang, Xiaofeng Dong, Yu‐Chuan Yan et al. · 2025 · Cancer Research
56. Joining the PARty: PARP Regulation of KDM5A during DNA Repair (and Transcription?)
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57. Oncometabolite 2-hydroxyglutarate suppresses basal protein levels of DNA polymerase beta that enhances alkylating agent and PARG inhibition induced cytotoxicity
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58. PARP1 bound to XRCC2 promotes tumor progression in colorectal cancer
    Kaiwu Xu, Zhige Yu, Tailiang Lu, Wei Peng, Yongqiang Gong, Chaowu Chen · 2024 · Discover Oncology
59. Alkylation induced cerebellar degeneration dependent on Aag and Parp1 does not occur via previously established cell death mechanisms
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60. Nicotinamide riboside–amino acid conjugates that are stable to purine nucleoside phosphorylase
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63. New Crystalline Salts of Nicotinamide Riboside as Food Additives
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64. Does oxidative DNA damage trigger histotoxic hypoxia via PARP1/AMP-driven mitochondrial ADP depletion-induced ATP synthase inhibition in Alzheimer’s disease?
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66. Poly(ADP-ribose) Polymerase 1 Mediates Rab5 Inactivation after DNA Damage
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67. UV-DDB as a General Sensor of DNA Damage in Chromatin: Multifaceted Approaches to Assess Its Direct Role in Base Excision Repair
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68. Base excision repair and nucleotide excision repair
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72. Protease-independent control of parthanatos by HtrA2/Omi
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75. SARM1 executes neuronal parthanatos and promotes excitotoxic cell death
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76. Respiratory Virus-Induced PARP1 Alters DC Metabolism and Antiviral Immunity Inducing Pulmonary Immunopathology
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77. PARP1 in melanoma: Mechanistic insights and implications for basic and clinical research
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99. Manifestations of Drug Toxicity on Mitochondria in the Nervous System
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100. Regulations of mitochondrial DNA repair by poly(ADP-Ribose) Polymerase 1
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