HOIP Deficiency Causes Embryonic Lethality by Aberrant TNFR1-Mediated Endothelial Cell Death

Peltzer, Nieves, Rieser, Eva, Taraborrelli, Lucia, Draber, Peter, Darding, Maurice, Pernaute, Barbara, Shimizu, Yutaka, Sarr, Aida +6 more·2014·Cell Reports
DOI 10.1016/j.celrep.2014.08.066

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  1. SPATA2: New insights into the assembly of the TNFR signaling complex
    Lisa Schlicher, Ulrich Maurer · 2016 · Cell Cycle
  2. Ripk1 and haematopoiesis: a case for LUBAC and Ripk3
    Alessandro Annibaldi, Pascal Meier · 2018 · Cell Death and Differentiation
  3. Cyclophilin J limits linear ubiquitin signaling and controls colorectal cancer progression
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  4. The Function of Ubiquitination in T-Cell Development
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  6. HOIL1 regulates group 2 innate lymphoid cell numbers and type 2 inflammation in the small intestine
    Matthew J. Wood, Jeffrey N. Marshall, Victoria L. Hartley, Ta‐Chiang Liu, Kazuhiro Iwaï, Thaddeus S. Stappenbeck, Donna A. MacDuff · 2022 · Mucosal Immunology
  7. Linear ubiquitination improves NFAT1 protein stability and facilitates NFAT1 signalling in Kawasaki disease
    Ying Miao, Guanghui Qian, Renxia Zhang, Yukang Yuan, Yibo Zuo, Yueyue Ding, Xuan Li, Yunjia Tang, Hui Zheng, Haitao Lv · 2023 · FEBS Journal
  8. Loss of FAS/FASL signalling does not reduce apoptosis in Sharpin null mice
    Christopher S. Potter, Kathleen A. Silva, Victoria E. Kennedy, Timothy M. Stearns, Harm HogenEsch, John P. Sundberg · 2017 · Experimental Dermatology
  9. Deficiency of the E3 Ubiquitin Ligase RBCK1 Causes Diffuse Brain Polyglucosan Accumulation and Neurodegeneration
    Mitchell Anthony Sullivan, Felix Nitschké, Erin E. Chown, Laura F. DiGiovanni, Mackenzie Chown, Ami M. Perri, Sharmistha Mitra, Xiaochu Zhao, Cameron A. Ackerley, Lori Israelian et al. · 2018 · bioRxiv (Cold Spring Harbor Laboratory)
  10. Synergistic involvement of the NZF domains of the LUBAC accessory subunits HOIL-1L and SHARPIN in the regulation of LUBAC function
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  11. LUBAC modulates CBM complex functions downstream of TRAF6 in T cells
    Carina Graß, Franziska Ober, Constanze Sixt, Bahareh Nemati Moud, Irina V. Antoshkina, Frederick Eberstadt, Alisa Puhach, Göksu Avar, Antonia Keßler, Thomas J. O’Neill et al. · 2025 · Nature Communications
  12. Mechanisms, regulation and clinical relevance of necroptosis
    Yuanxin Yang, Huipeng Jiao, Daichao Xu · 2026 · Nature Reviews Molecular Cell Biology
  13. Biochemical and functional characterization of the N-terminal ubiquitin-like domain of human SHARPIN
    Wenlei Ma, Ying Lu, Jing Qi, Yongmei Zuo, Chenchen Wang, Xiaodong Zheng, Jiafu Liu · 2021 · Protein Expression and Purification
  14. An interaction between OTULIN and SCRIB uncovers roles for linear ubiquitination in planar cell polarity
    Stephanie M. Almeida, Sofiia Ivantsiv, Rieko Niibori, Wade H. Dunham, Brooke A. Green, Liang Zhao, Anne‐Claude Gingras, Sabine P. Cordes · 2023 · Disease Models & Mechanisms
  15. Inactivation of PI3K-C2α deregulates cell death pathways and sensitizes to endotoxic shock
    York Posor, Sarah E. Conduit, Wayne P Pearce, Daniele Morelli, Georgia Constantinou, Maria A. Whitehead, Neil James Sebire, Cheryl L. Scudamore, Nieves Peltzer, Henning Walczak et al. · 2025 · Proceedings of the National Academy of Sciences
  16. HOIL1 Regulates Group 3 Innate Lymphoid Cells in the Colon and Protects against Systemic Dissemination, Colonic Ulceration, and Lethality from Citrobacter rodentium Infection
    Victoria L. Hartley, Arwa Qaqish, Matthew J. Wood, Brian T. Studnicka, Kazuhiro Iwaï, Ta‐Chiang Liu, Donna A. MacDuff · 2023 · The Journal of Immunology
  17. Fine-tuning ALK1 linear polyubiquitination to control angiogenesis
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  18. STK4 inhibits the E3 activity of HOIP by phosphorylating its allosteric ubiquitin-binding site
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  19. [Intrauterine invagination in a newborn infant].
    Wilco C. W. R. Zijlmans, F A Nabben · 1993 · PubMed
  20. Glycosylation as a tracer of off-target Cre-lox activation in development
    Leandre M. Glendenning, Kalob M. Reynero, Brian A. Cobb · 2024 · Glycobiology
  21. T cells use TNF and IFNγ for paracrine killing with target discrimination programmed by pathogen-derived factors
    Matthew C. Guttormson, Erica N. Krogman, Allison R. Carr, Skylar A. Rizzo, Josey Muske, Maia Ziaee, Nicholas R. Therrien, Nicholas D. Sun, Romina Ghale, Michael J. Medlyn et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
  22. IAPs and Resistance to Death Receptors in Cancer
    Laurence Dubrez, Simone Fulda · 2017 · Resistance to targeted anti-cancer therapeutics
  23. TNF and Ubiquitination
    Sebastian Kupka, Henning Walczak · 2017 · Encyclopedia of Life Sciences
  24. A role for SHARPIN in platelet linear protein ubiquitination and function
    Samantha Moore, Xueqiang Zhao, Shahida Mallah, Alastair W. Poole, Stuart J. Mundell, James L. Hutchinson, Ingeborg Hers · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
  25. The ubiquitin ligase HOIL-1L regulates immune responses by interacting with linear ubiquitin chains
    Carlos Gomez Diaz, Gustav Jonsson, Katrin Schodl, Luiza Deszcz, Annika Bestehorn, Kevin Eislmayr, Jorge Almagro, Anoop Kavirayani, Lilian M Fennell, Astrid Hagelkruys et al. · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
  26. OTULIN Deficiency-Associated Disease Spectrum
    Ivona A Aksentijevich · 2018 · Springer eBooks
  27. Faculty Opinions recommendation of LUBAC prevents lethal dermatitis by inhibiting cell death induced by TNF, TRAIL and CD95L.
    Michael McDermott, Heledd Jarosz-Griffiths · 2019 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
  28. Faculty Opinions recommendation of LUBAC is essential for embryogenesis by preventing cell death and enabling haematopoiesis.
    David Lawrence Vaux, Najoua Lalaoui · 2018 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
  29. Faculty Opinions recommendation of LUBAC is essential for embryogenesis by preventing cell death and enabling haematopoiesis.
    Vishva M. Dixit, Kim Newton · 2018 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
  30. OTULIN Deficiency-Associated Disease Spectrum
    Ivona A Aksentijevich · 2020 · Springer eBooks
  31. Atopic Dermatitis Related to RNF31 Genetic Variant
    César Daniel Alonso-Bello, Sonia Chávez-Ocaña, Carol Vivian Moncayo-Coello, María Isabel Rojo-Gutiérrez · 2023 · OALib
  32. Mind bomb 2 limits inflammatory dermatitis in Sharpin mutant mice independently of cell death
    Daniel S. Simpson, Holly Anderton, Jumana M. Yousef, Vineet Vaibhav, Simon A. Cobbold, Esther Bandala‐Sanchez, Andrew J. Kueh, Laura F. Dagley, Marco J. Herold, John Silke et al. · 2023 · PNAS Nexus
  33. Novel functions of LUBAC-mediated M1 poly-ubiquitination in TNFR1-mediated necroptosis
    Nadine Weinelt · 2024
  34. Met1-linked ubiquitination in cell signaling regulation
    Yanmin Guo, Yuqin Zhao, Yu‐Sheng Cong · 2024 · Biophysics Reports
  35. Antibody-dependent Intracellular neutralisation by TRIM21 is potentiated by HOIP and linear ubiquitin chains
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  36. Bendamustine switches TNF receptor superfamily signal from a survival to a death signal in B-cell lymphomas
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  37. Inflammatory cell death and leukemia treatment
    Saqib Ishaq, Sajida Afzal, Shabir Ahmad Usmani, Ibtasam Wajid, Abdul Aziz, Raheel Tahir, Ajaz Ahmad, Amin Ullah · 2025 · Critical Reviews in Oncology/Hematology
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    Yang, Huijie, Xue, Min, Su, Peng, Zhou, Yan, Li, Xin, Li, Zhongbo, Xia, Yan, Chenmiao Zhang, Mingxi Fu, Xiuxia Zheng et al. · 2023 · Figshare
  39. Additional file 2 of RNF31 represses cell progression and immune evasion via YAP/PD-L1 suppression in triple negative breast Cancer
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  43. GPS2 regulates embryonic angiogenesis by enhancing endothelial cell survival through stabilizing HOIP
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  44. Deubiquitinating enzyme MINDY2 regulates TNF-α-induced cell death by targeting RIPK1
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  45. Etude du rôle de MYD88 et des voies NF-kB dans l'émergence des lymphomes B
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  48. SHARPIN restrains IL-33 release by stromal cells to control ILC2 inflammation
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  49. Combination of enhanced gene activation and cell death causes lethal inflammatory pulmonary fibrosis
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  50. RNF213 M1-ubiquitinates damaged mitochondria to activate pro-inflammatory NF-κB signaling
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