Regulation of Memory Formation by the Transcription Factor XBP1

Martínez, Gabriela, Vidal, René L., Mardones, Pablo, Serrano, Felipe G., Ardiles, Alvaro O., Wirth, Craig, Valdés, Pamela, Thielen, Peter +7 more·2016·Cell Reports

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  2. The molecular mechanisms of excessive hippocampal endoplasmic reticulum stress depressing cognition-related proteins expression and the regulatory effects of Nrf2.
    Ming Cai, Jing-Yun Hu, Bei-Bei Liu, Jing-Jing Li, Feng Li, Shujie Lou · 2020 · Neuroscience
  3. Comparative studies of vertebrate iduronate 2-sulfatase (IDS) genes and proteins: evolution of A mammalian X-linked gene
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  4. Diabetic retinopathy and Alzheimer's disease: Convergence of the unfolded protein response in neurodegeneration
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  5. Advanced glycation end products in brain during aging.
    Utkarsh Reddy Addi, Sneha Jakhotia, S. Reddy, G. Reddy · 2022 · Chemico-Biological Interactions
  6. The Unfolded Protein Response and Autophagy as Drug Targets in Neuropsychiatric Disorders
    Vignesh Srinivasan, Laura Korhonen, Dan Lindholm · 2020 · Frontiers in Cellular Neuroscience
  7. Control of mammalian brain aging by the unfolded protein response (UPR)
    F. Cabral-Miranda, Giovani Tamburini, Gabriela Martínez, D. Medinas, Y. Gerakis, T. Miedema, C. Durán-Aniotz, Álvaro O. Ardiles, C. González, C. Sabusap et al. · 2020 · bioRxiv
  8. The physiological role of the unfolded protein response in the nervous system
    Shuang-Chan Wu, Wen-Sheng Lin · 2024 · Neural Regeneration Research
  9. The broad spectrum of signaling pathways regulated by unfolded protein response in neuronal homeostasis
    Atsushi Saito, Kazunori Imaizumi · 2017 · Neurochemistry International
  10. Astrocytic deletion of protein kinase R‐like ER kinase ( PERK ) does not affect learning and memory in aged mice but worsens outcome from experimental stroke
    Anirudhya Lahiri, James C. Walton, Ning Zhang, Neil Billington, A. Courtney DeVries, Gordon P. Meares · 2023 · Journal of Neuroscience Research
  11. Dual role of IRE1α-XBP1 signaling in neurodegenerative diseases.
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  12. Differential roles of exogenous protein disulfide isomerase A3 on proliferating cell and neuroblast numbers in the normal and ischemic gerbils
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  13. Link between endoplasmic reticulum stress and autophagy in neurodegenerative diseases
    Toru Hosoi, Jun Nomura, Keigo Tanaka, K. Ozawa, A. Nishi, Y. Nomura · 2017 · Endoplasmic Reticulum Stress in Diseases
  14. ER stress in neurodegenerative disease: from disease mechanisms to therapeutic interventions
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  15. Wilm’s tumor 1 promotes memory flexibility
    Chiara Mariottini, L. Munari, Ellen Gunzel, Joseph M. Seco, N. Tzavaras, J. Hansen, S. Stern, Virginia Gao, H. Aleyasin, E. Azeloglu et al. · 2017 · bioRxiv
  16. Endoplasmic reticulum unfolded protein response transcriptional targets of XBP-1s mediate rescue from tauopathy
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  19. Hippocampal Endoplasmic Reticulum Stress Hastens Motor and Cognitive Decline in Adult Male Rats Sustainedly Exposed to High-Sucrose Diet
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  20. Proteostasis and resilience: on the interphase between individual's and intracellular stress.
    M. Díaz-Hung, C. Hetz · 2022 · Trends in endocrinology and metabolism
  21. Enhancing cognition: The power of neuroplasticity.
    Iqra Mukhtar, Kanwal Iftikhar · 2025 · Ageing Research Reviews
  22. CDNF Exerts Anxiolytic, Antidepressant-like, and Procognitive Effects and Modulates Serotonin Turnover and Neuroplasticity-Related Genes
    A. Tsybko, D. Eremin, T. Ilchibaeva, N. Khotskin, V. Naumenko · 2024 · International Journal of Molecular Sciences
  23. ATF6β Deficiency Elicits Anxiety-like Behavior and Hyperactivity Under Stress Conditions
    Takashi Tanaka, Dinh Thi Nguyen, Nichakarn Kwankaew, Megumi Sumizono, Reika Shinoda, Hiroshi Ishii, Mika Takarada‐Iemata, Tsuyoshi Hattori, Seiichi Oyadomari, Nobuo Kato et al. · 2023 · Neurochemical Research
  24. The regulation of animal behavior by cellular stress responses
    Neşem P. Özbey, M. Thompson, Rebecca C. Taylor · 2021 · Experimental Cell Research
  25. Making of BDNF: role of promoters, enhancers, and untranslated regions
    Eli‐Eelika Esvald, Annela Avarlaid, Indrek Koppel, Jürgen Tuvikene, Tõnis Timmusk · 2026 · Trends in Neurosciences
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    Bao-Hua Li, Yi-Peng Shi, Meng-Yu Liu, W. Cao, Fu-Yuan Zhang, Ze-Feng Kang · 2025 · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
  27. Beneficial behavioral effects of chronic cerebral dopamine neurotrophic factor (CDNF) infusion in the N171-82Q transgenic model of Huntington’s disease
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    Theodora Panagaki, Elisa B. Randi, Csaba Szabó, Christian Hölscher · 2023 · Journal of Parkinson s Disease
  33. Research progress of the UPR mechanism and its effect on improving foreign protein expression.
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  34. Bursting the unfolded protein response accelerates axonal regeneration
    M. Oñate, F. Court, C. Hetz · 2016 · Neural Regeneration Research
  35. Brain Inflammation and Endoplasmic Reticulum Stress
    I. Çakır, E. Nillni · 2018 · Springer eBooks
  36. An investigation of the endoplasmic reticulum stress in obesity exposure in the prenatal period.
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  38. Disruption of Endoplasmic Reticulum Proteostasis in Age-Related Nervous System Disorders
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  41. Early and late chaperone intervention therapy boosts XBP1s and ADAM10, restores proteostasis, and rescues learning in Alzheimer’s Disease mice
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  42. Integrating Dopamine and BDNF Hypotheses: The Role of Dopamine–BDNF Crosstalk in Neuropathologies
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    Ching-Feng Cheng, Evelyn Cheng, Hui-Chen Ku · 2024 · Tzu-Chi Medical Journal
  47. Early and Late Chaperone Intervention Therapy Boosts XBP1s and ADAM10, Restores Proteostasis, and Rescues Learning in Alzheimer’s Disease Mice
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  48. Beyond the unfolded protein response: Disclosing the role of XBP1s in Alzheimer's disease.
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    Diptavo Dutta, Yuan He, A. Saha, Marios Arvanitis, A. Battle, N. Chatterjee · 2020 · medRxiv
  50. The role of hippocampus during observational learning
    Yerko Fuentealba, J. Valdés · 2019 · bioRxiv (Cold Spring Harbor Laboratory)
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    Abhijeet Kapoor, K. Kelleher, S. Underhill, Sankalp Jain, Darian Williams, Brandon K. Harvey, Mark J. Henderson · 2026 · Frontiers in Pharmacology
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  57. Control of mammalian brain ageing by the unfolded protein response transcription factor XBP1
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  58. A stress-free stress response
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  61. Regulation of IAPP transcription by spliced XBP1
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