Chd8 Mutation Leads to Autistic-like Behaviors and Impaired Striatal Circuits
Platt, Randall J., Zhou, Yang, Slaymaker, Ian M., Shetty, Ashwin S., Weisbach, Niels R., Kim, Jin-Ah, Sharma, Jitendra, Desai, Mitul +5 more·2017·Cell Reports
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Items 201–239 of 239
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- Principal Molecular Pathways Affected in Autism Spectrum DisorderSalma N. Younes, Rana Al‐Jurf, Sara Hammuda, Gheyath K. Nasrallah, Hatem Zayed, M. Walid Qoronfleh, Mohamed Ali Ismail, Tom Farrell, Hilal Al-Rifai, Muthanna M. Samara et al. · 2022 · Nutritional neurosciences
- Mouse Population Genetics Phenocopies Heterogeneity of Human Chd8 HaploinsufficiencyManal Tabbaa, Allison T. Knoll, Pat R. Levitt · 2022 · SSRN Electronic Journal
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- CHD8 adulthood microglial knockout induces behavioral, morphological, and transcriptional changes in a sex-dependent mannerOrly Weissberg, Dmitrity Getselter, Evan Elliott · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
- Reviewer #2 (Public Review): Cntnap2 loss drives striatal neuron hyperexcitability and behavioral inflexibilityKatherine R Cording, Emilie M Tu, Hongli Wang · 2024 · eLife
- eLife Assessment: Cntnap2 loss drives striatal neuron hyperexcitability and behavioral inflexibilityJun Ding · 2024 · eLife
- Reviewer #1 (Public Review): Cntnap2 loss drives striatal neuron hyperexcitability and behavioral inflexibilityKatherine R Cording, Emilie M Tu, Hongli Wang · 2024 · eLife
- Reviewer #3 (Public Review): Cntnap2 loss drives striatal neuron hyperexcitability and behavioral inflexibilityKatherine R Cording, Emilie M Tu, Hongli Wang · 2024 · eLife
- Autism-associated ASPM variant causes macrocephaly and social-cognitive deficits in miceSarika Singh, Hyopil Kim, Alev Ecevitoglu, Renee Chasse, Alexis M Ludko, Basavaraju G. Sanganahalli, Vishaak Gangasandra, Sung Rye Park, Siu‐Pok Yee, James J. Grady et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
- Additional file 3 of Oxytocin ameliorates impaired social behavior in a Chd8 haploinsufficiency mouse model of autismЧерепанов Станислав Михайлович, Maria Gerasimenko, Teruko Yuhi, Kazumi Furuhara, Chiharu Tsuji, Yokoyama, Shigeru, Keiichi I. Nakayama, Masaaki Nishiyama, Haruhiro Higashida · 2021 · Figshare
- Additional file 3 of Chd8 mutation in oligodendrocytes alters microstructure and functional connectivity in the mouse brainAtsuki Kawamura, Yoshifumi Abe, Seki, Fumiko, Katayama, Yuta, Nishiyama, Masaaki, Takata, Norio, Tanaka, Kenji F., Okano, Hideyuki, Keiichi I. Nakayama · 2020 · Figshare
- Additional file 2 of Oxytocin ameliorates impaired social behavior in a Chd8 haploinsufficiency mouse model of autismCherepanov, Stanislav M., Maria Gerasimenko, Teruko Yuhi, Kazumi Furuhara, Chiharu Tsuji, Yokoyama, Shigeru, Keiichi I. Nakayama, Masaaki Nishiyama, Haruhiro Higashida · 2021 · Figshare
- Additional file 1 of Exploring the role of RALYL in Alzheimer’s disease reserve by network-based approachesZhang, Yixuan, Wang, Jiali, Liu, Xiaoquan, Liu, Haochen · 2020 · Figshare
- Additional file 1 of Oxytocin ameliorates impaired social behavior in a Chd8 haploinsufficiency mouse model of autismЧерепанов Станислав Михайлович, Maria Gerasimenko, Teruko Yuhi, Kazumi Furuhara, Chiharu Tsuji, Yokoyama, Shigeru, Keiichi I. Nakayama, Masaaki Nishiyama, Haruhiro Higashida · 2021 · Figshare
- Additional file 1 of Distinct, dosage-sensitive requirements for the autism-associated factor CHD8 during cortical developmentHurley, Shaun, Conor Mohan, Philipp Suetterlin, Robert A. Ellingford, Kimberley L. H. Riegman, Jacob Ellegood, Caruso, Angela, Caterina Michetti, Olivier Brock, Romy Evans et al. · 2021 · Figshare
- Additional file 6 of Chd8 haploinsufficiency impairs early brain development and protein homeostasis later in lifeJessica A. Jiménez, Travis Ptacek, Alex H. Tuttle, Ralf S. Schmid, Moy, Sheryl S., Jeremy M. Simon, Mark J. Zylka · 2020 · Figshare
- Zahir Friedman SyndromeFarah Zahir · 2025 · Springer eBooks
- Molecular Interactions of Chd8 in Mouse Brain Highlights a Role in Chromatin-Associated RNA ProcessingEmily Smith, César P. Canales, Mathew W. Kenaston, Nicolas Seban, Ayanna A. Wade, Ethan Fenton, Cory Ardekani, Stephanie Lozano, Nickolas C. Chu, Daniela Perla et al. · 2025 · SSRN Electronic Journal
- Récepteurs synaptiques et troubles du neuro-développement : approches translationnelles pour la caractérisation fonctionnelle des gènes PTCHD1 et GRID1Dévina C. Ung · 2017 · theses.fr (ABES)
- The role of Chd7 & Chd8 chromatin remodelers in oligodendrogenesis and (re)myelinationCorentine Marie · 2017 · theses.fr (ABES)
- Etude du rôle de CHD8 dans les troubles gastro-intestinaux associés aux troubles du spectre autistiqueGaëlle Hayot · 2020
- Etude du développement cortical à travers la caractérisation d'un modèle murin d'autisme et l'inférence des interactions cellulaires par séquençage en cellules uniquesRémi Mathieu · 2022
- Les troubles du spectre autistique au Liban : une étude épidémiologique et génétiquePerla Gerges · 2022
- PAK1 and NF2 antagonist functions in regulating central nervous system myelination : from modulation of oligodendrocyte cytoskeleton to myelin sheath formationNoémie Adès · 2024 · theses.fr (ABES)
- Histone acetylation and methylation in rare diseases: from molecular mechanisms to clinical presentationsBurcu Akman, Semra Gürsoy, Pınar Gençpınar, Ayşe Polat, Ayşe Semra Hız, Yavuz Oktay, Tahsin Stefan Barakat, Uğur Özbek, Serap Erkek · 2026 · Frontiers in Cell and Developmental Biology
- Perineuronal nets in cerebellar nuclei neurons orchestrate social behaviour via regulation of neuronal activity in circuits innervated by the cerebellumKyota Fujita, Hong Zhu, Chiharu Tsuji, Atsuki Kawamura, Masaaki Nishiyama, Haruhiro Higashida, Shigeru Yokoyama · 2026 · Translational Psychiatry
- A Novel Variant of the CHD8 Gene in a Patient with Autism Spectrum DisorderElena Falcone, Alessia Bauleo, Laura De Stefano, Rossella Brando, Sabrina Maietta, Elisabetta Tabolacci, Alberto Montesanto, Vincenza Pace, Rosalbina Apa, Domenica Puntorieri et al. · 2026 · Genes
- Adult-onset dystonia associated with CHD8 truncating variants: case series and targeted literature reviewOğuzhan Yılmaz, Uğur Olgun Çelik, Ebru Erzurumluoğlu Gökalp, Sinem Kocagil, Fatma Nazlı Durmaz Çelik, Erdi Şahin, Bedia Samancı, Başar Bılgıç, Hasmet Ayhan Hanagasi, Oğuz Çilingir · 2026 · Neurogenetics
- Male-Biased Social Deficits in Chd8+/R2219* Mouse Model of Autism Linked to Hippocampal AbnormalitiesQ H Zhang, Yang Qiao, Huixian Li, Jiali Zeng, Jingwen Chen, H J Zhou, Yuzheng Hu, Jianhong Luo · 2026 · Neuroscience Bulletin
- Zahir Friedman SyndromeFarah Zahir · 2026 · Springer eBooks
- Molecular Acrobats: How CHD Remodelers Shape the Genetic Playground to License Cell IdentityIsa Özdemir, Sarah J. Hainer · 2026 · BioEssays
- Mitochondrial–Epigenetic Crosstalk in Autism Spectrum Disorder: Linking Cellular Stress to Synaptic Dysfunction and Treatment ResistanceDijie Liu, Kai Tao, Yuxia Wang, Yuanhao Sun, Shiyong Wang · 2026 · Molecular Neurobiology
- Age-dependent reorganization of behavioral and striatal function in Cntnap2 knockout miceMathieu Thabault, Cloé Fernandes‐Gomes, Cloé Alcaraz, Anaïs Balbous, Pierre‐Olivier Fernagut, Laurie Galvan · 2026 · Neurobiology of Disease
- Animal models of autism spectrum disorder: Bridging biology to behaviourPilar Martinez Olondo, Alban de Kerchove d’Exaerde · 2026 · Developmental Medicine & Child Neurology
- Recent Advances in Autism Spectrum Disorder Research on Epigenetics and Personalised MedicineRasa Khosrofar, Iman Morshedi, Mohammad Behzadpour, Narges Afzali, Reza Shah Hosseini, Alireza Aghili · 2026 · International Journal of Developmental Neuroscience