The DOI matches its Crossref record; 13 of the 13 references it cites were found in a registry or an index.
CRISPR-Mediated Integration of Large Gene Cassettes Using AAV Donor Vectors
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“In 2017, Bak et al. demonstrated that a dual AAV approach could be used to integrate large transgenes into endogenous DNA using CRISPR [27].”
From Viral Delivery Systems for CRISPR (2019) · cites this paper as [27]
In the citing paper
“This method was successful in the K562 cell line, primary human T cells, and CD34+ hematopoietic stem and progenitor cells.”
From Viral Delivery Systems for CRISPR (2019) · cites this paper as [27]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Yin, H., Song, C.-Q., Dorkin, J. R., Zhu, L. J., Li, Y., Wu, Q., Park, A., Yang, J., Suresh, S., Bizhanova, A., et al. (2016) · Nature Biotechnology · doi:10.1038/nbt.3471 · Cited by 876
CRISPR/Cas9 β-globin gene targeting in human haematopoietic stem cells
Dever, D. P., Bak, R. O., Reinisch, A., Camarena, J., Washington, G., Nicolas, C. E., Pavel-Dinu, M., Saxena, N., Wilkens, A. B., Mantri, S., et al. (2016) · Nature · doi:10.1038/nature20134 · Cited by 864
Self-citationLombardo, A., Genovese, P., Beausejour, C. M., Colleoni, S., Lee, Y.-L., Kim, K. A., Ando, D., Urnov, F. D., Galli, C., Gregory, P. D., et al. (2007) · Nature Biotechnology · doi:10.1038/nbt1353 · Cited by 845
A dual AAV system enables the Cas9-mediated correction of a metabolic liver disease in newborn mice
Yang, Y., Wang, L., Bell, P., McMenamin, D., He, Z., White, J., Yu, H., Xu, C., Morizono, H., Musunuru, K., et al. (2016) · Nature Biotechnology · doi:10.1038/nbt.3469 · Cited by 556 · cited 1×
“…virus (AAV), can transduce both dividing and non-dividing cells and have recently been effectively used as donor vectors for HR both in vitro and in vivo (Sather et al., 2015, Wang et al., 2015, DeWitt et al., 2016, Yang et al., 2016, Yin et al., 2016, Dever et al., 2016, De Ravin et al., 2017).”
MethodTargeted genome editing in human repopulating haematopoietic stem cells
Genovese, P., Schiroli, G., Escobar, G., Di Tomaso, T., Firrito, C., Calabria, A., Moi, D., Mazzieri, R., Bonini, C., Holmes, M. C., et al. (2014) · Nature · doi:10.1038/nature13420 · Cited by 555
Brown, B. D., Venneri, M. A., Zingale, A., Sergi, L. S., & Naldini, L. (2006) · Nature Medicine · doi:10.1038/nm1398 · Cited by 484
Grieger, J. C., & Samulski, R. J. (2005) · Journal of Virology · doi:10.1128/jvi.79.15.9933-9944.2005 · Cited by 419
Wang, J., Exline, C. M., DeClercq, J. J., Llewellyn, G. N., Hayward, S. B., Li, P. W.-L., Shivak, D. A., Surosky, R. T., Gregory, P. D., Holmes, M. C., et al. (2015) · Nature Biotechnology · doi:10.1038/nbt.3408 · Cited by 261
De Ravin, S. S., Li, L., Wu, X., Choi, U., Allen, C., Koontz, S., Lee, J., Theobald-Whiting, N., Chu, J., Garofalo, M., et al. (2017) · Science Translational Medicine · doi:10.1126/scitranslmed.aah3480 · Cited by 258
Sather, B. D., Romano Ibarra, G. S., Sommer, K., Curinga, G., Hale, M., Khan, I. F., Singh, S., Song, Y., Gwiazda, K., Sahni, J., et al. (2015) · Science Translational Medicine · doi:10.1126/scitranslmed.aac5530 · Cited by 223
Flagged first, then by citations
Research works printed but not linked: 19
- Aurnhammer, 2012, Universal real-time PCR for the detection and quantification of adeno-associated virus serotype 2-derived inverted terminal repeat sequences, Hum. Gene Ther. Methods, 23, 18, 10.1089/hgtb.2011.034 · DOI
- Barzel, 2015, Promoterless gene targeting without nucleases ameliorates haemophilia B in mice, Nature, 517, 360, 10.1038/nature13864 · DOI
- Basiri, 2017, The convenience of single homology arm donor DNA and CRISPR/Cas9-nickase for targeted insertion of long DNA fragment, Cell J., 18, 532
- Chicaybam, 2013, An efficient low cost method for gene transfer to T lymphocytes, PLoS ONE, 8, e60298, 10.1371/journal.pone.0060298 · DOI
- DeWitt, 2016, Selection-free genome editing of the sickle mutation in human adult hematopoietic stem/progenitor cells, Sci. Transl. Med., 8, 360ra134, 10.1126/scitranslmed.aaf9336 · DOI · Paper page
- Frischmeyer, 2002, An mRNA surveillance mechanism that eliminates transcripts lacking termination codons, Science, 295, 2258, 10.1126/science.1067338 · DOI
- Hendel, 2014, Quantifying genome-editing outcomes at endogenous loci with SMRT sequencing, Cell Rep., 7, 293, 10.1016/j.celrep.2014.02.040 · DOI
- Hendel, 2015, Chemically modified guide RNAs enhance CRISPR-Cas genome editing in human primary cells, Nat. Biotechnol., 33, 985, 10.1038/nbt.3290 · DOI · Paper page
- Holkers, 2014, Adenoviral vector DNA for accurate genome editing with engineered nucleases, Nat. Methods, 11, 1051, 10.1038/nmeth.3075 · DOI · Paper page
- Knipping, 2017, Genome-wide specificity of highly efficient TALENs and CRISPR/Cas9 for T cell receptor modification, Mol. Ther. Methods Clin. Dev., 4, 213, 10.1016/j.omtm.2017.01.005 · DOI
- Kung, 2013, Effects of DNA size on transformation and recombination efficiencies in Xylella fastidiosa, Appl. Environ. Microbiol., 79, 1712, 10.1128/AEM.03525-12 · DOI
- Nakai, 2000, Increasing the size of rAAV-mediated expression cassettes in vivo by intermolecular joining of two complementary vectors, Nat. Biotechnol., 18, 527, 10.1038/75390 · DOI · Paper page
- Perez, 2005, Factors affecting double-strand break-induced homologous recombination in mammalian cells, Biotechniques, 39, 109, 10.2144/05391GT01 · DOI
- Ryan, 2010, Pharmacological inhibition of EGFR signaling enhances G-CSF-induced hematopoietic stem cell mobilization, Nat. Med., 16, 1141, 10.1038/nm.2217 · DOI
- Sun, 2000, Overcoming adeno-associated virus vector size limitation through viral DNA heterodimerization, Nat. Med., 6, 599, 10.1038/75087 · DOI · Paper page
- Takahashi, 1998, A potential molecular approach to ex vivo hematopoietic expansion with recombinant epidermal growth factor receptor-expressing adenovirus vector, Blood, 91, 4509, 10.1182/blood.V91.12.4509.412a01_4509_4515 · DOI
- van Hoof, 2002, Exosome-mediated recognition and degradation of mRNAs lacking a termination codon, Science, 295, 2262, 10.1126/science.1067272 · DOI
- Zhang, 2014, Targeted genome correction by a single adenoviral vector simultaneously carrying an inducible zinc finger nuclease and a donor template, J. Biotechnol., 188, 1, 10.1016/j.jbiotec.2014.08.003 · DOI
- Zhang, 2014, Multiple copies of a linear donor fragment released in situ from a vector improve the efficiency of zinc-finger nuclease-mediated genome editing, Gene Ther., 21, 282, 10.1038/gt.2013.83 · DOI
Cited by
Sorted by citations
Vakulskas, C. A., Dever, D. P., Rettig, G. R., Turk, R., Jacobi, A. M., Collingwood, M. A., Bode, N. M., McNeill, M. S., Yan, S., Camarena, J., et al. (2018) · Nature Medicine · doi:10.1038/s41591-018-0137-0 · Cited by 782
Self-citationCRISPR/Cas9 genome editing in human hematopoietic stem cells.
Bak, R. O., Dever, D. P., & Porteus, M. H. (2018) · Nature Protocols · doi:10.1038/nprot.2017.143 · Cited by 319
Self-citationViral Delivery Systems for CRISPR
Xu, C. L., Ruan, M. Z. C., Mahajan, V. B., & Tsang, S. H. (2019) · Viruses · doi:10.3390/v11010028 · Cited by 277
Methods and Applications of CRISPR-Mediated Base Editing in Eukaryotic Genomes
Hess, G. T., Tycko, J., Yao, D., & Bassik, M. C. (2017) · Molecular Cell · doi:10.1016/j.molcel.2017.09.029 · Cited by 234
Bak, R. O., Dever, D. P., Reinisch, A., Cruz Hernandez, D., Majeti, R., & Porteus, M. H. (2017) · eLife · doi:10.7554/elife.27873 · Cited by 122
Self-citation
Metadata
- Authors
- Bak, R. O., & Porteus, M. H.
- Venue
- Cell Reports
- Publisher
- Elsevier BV
- Published
- 2017-07
- Volume
- 20
- Issue
- 3
- Pages
- 750-756
- ISSN
- 2211-1247
- PMC
- PMC5568673
- Cited by
- 124
- References
- 13
- Language
- en
- Licence
- Funders
- Danish Council for Independent Research, Medical Sciences (DFF-1333-00106B, DFF-1331-00735B)
- Amon Carter Foundation
- Laurie Kraus Lacob
- NIH (R01-AI120766)
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
