Human Huntington's disease iPSC-derived cortical neurons display altered transcriptomics, morphology, and maturation

Mehta, Shagun R., Tom, Colton M., Wang, Yizhou, Bresee, Catherine, Rushton, David, Mathkar, Pranav P., Tang, Jie, Mattis, Virginia B.·2018·Cell Reports

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Items 101–112 of 112

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  3. Additional file 1 of RNA-seq analysis reveals significant transcriptome changes in huntingtin-null human neuroblastoma cells
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  4. Mouse models to interrogate the developmental pathogenesis of Huntington's disease
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  5. Abnormal cortical development sets the stage in Huntington disease
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  6. Régulation du transport axonal par l'activité neuronale : Implication pour le développement des réseaux neuronaux
    Eve Moutaux · 2020
  7. Functional impacts of Huntingtin lowering on the synaptic maturation and activity of neuronal networks derived from human induced pluripotent stem cells
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  8. Fragile polyQ assemblies cause Golgipathy in Huntington’s disease
    Lixiang Ma, Xinyu Chen, Yang Liu, Lijun Dai, Fangzhou Ye, Weiqi Yang, Hada Buhe, Jixin Ma, Chenyun Song, Li Li et al. · 2026 · eLife
  9. Fragile polyQ assemblies cause Golgipathy in Huntington’s disease
    Lixiang Ma, Xinyu Chen, Yang Liu, Lijun Dai, Fangzhou Ye, Weiqi Yang, Hada Buhe, Jixin Ma, Chenyun Song, Li Li et al. · 2026 · eLife
  10. Advances in neural organoids: structural organization, disease modeling, and applications in gene therapy
    Evelina Nasybullina, Elvira Ruslanovna Akhmetzyanova, Albert Anatolyevich Rizvanov, Yana Olegovna Mukhamedshina · 2026 · Molecular Biology Reports
  11. Negotiating in a Foreign Land : Understanding the Curious Interactions Between Intracellular Mitochondria and Internalized Nanoparticles
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  12. Multi-omic profiling of 85 iPSC lines from familial dementia reveals cellular diversity and regulators of organoid development
    Le Qi, Taylor B. Bertucci, Susan M. Borden, Brigitte L. Arduini, Steven Lotz, Kathryn R. Bowles, Alison Goate, Celeste M M. Karch, Sally Temple, Daniel H. Geschwind · 2026 · Neuron