FGF21 Signals Protein Status to the Brain and Adaptively Regulates Food Choice and Metabolism

Hill, Cristal M., Laeger, Thomas, Dehner, Madeleine, Albarado, Diana C., Clarke, Blaise, Wanders, Desiree, Burke, Susan J., Collier, J. Jason +6 more·2019·Cell Reports

Cited by (230)

Items 101–200 of 230

  1. Hepatic interoception in health and disease
    Hans‐Rudolf Berthoud, Heike Münzberg, Christopher D. Morrison, Winfried Neuhuber · 2024 · Autonomic Neuroscience
  2. Glucagon and energy expenditure; Revisiting amino acid metabolism and implications for weight loss therapy
    Hope, D.C.D., Tan, T.M-M. · 2023 · Peptides
  3. Role of peptide hormones in the adaptation to altered dietary protein intake
    Rose, Adam J. · 2019 · Nutrients
  4. Protein restriction reprograms the multi-organ proteomic landscape of mouse aging
    Tian Lu, Yuting Xie, Yingrui Wang, Xiling Lin, Xue Cai, Yuqi Zhang, Zongxiang Nie, Chang Su, Wanglong Gou, Hong Zhang et al. · 2025 · Cell
  5. Diet Protein Content and Individual Phenotype Affect Food Intake and Protein Appetence in Rats
    Gaëlle Champeil‐Potokar, Lucas Crossouard, Nathalie Jérôme, Christian Ouali, Nicolas Darcel, Olga Davidenko, Olivier Rampin, Vincent Bombail, Isabelle Denis · 2021 · Journal of Nutrition
  6. The Role of Reduced Methionine in Mediating the Metabolic Responses to Protein Restriction Using Different Sources of Protein
    Han Fang, Kirsten P. Stone, Sujoy Ghosh, Laura A. Forney, Thomas W. Gettys · 2021 · Nutrients
  7. Protein preference and elevated plasma FGF21 induced by dietary protein restriction is similar in both male and female mice
    K. Linnea Volcko, James E. McCutcheon · 2022 · Physiology & Behavior
  8. Exploring endocrine FGFs - structures, functions and biomedical applications
    Phuc Phan · 2024 · International Journal of Biochemistry and Molecular Biology
  9. Geroprotective interventions in the 3xTg mouse model of Alzheimer’s disease
    Michelle M. Sonsalla, Dudley W. Lamming · 2023 · GeroScience
  10. Hepatokines, bile acids and ketone bodies are novel Hormones regulating energy homeostasis
    Gabriella Garruti, Jacek Baj, Angelo Cignarelli, Sebastio Perrini, Francesco Giorgino · 2023 · Frontiers in Endocrinology
  11. Brown and beige adipose tissue‐derived metabokine and lipokine inter‐organ signalling in health and disease
    Anna Malicka-Durczak, Aysha Ali, Amanda D. V. MacCannell, Lee D. Roberts · 2024 · Experimental Physiology
  12. What does self‐selection of dietary proteins in rats tell us about protein requirements and body weight control?
    Patrick C. Even, Joséphine Gehring, Daniel Tomé · 2021 · Obesity Reviews
  13. The impacts of different dietary restriction regimens on aging and longevity: from yeast to humans
    Tsui‐Ting Ching, Ao‐Lin Hsu · 2025 · Journal of Biomedical Science
  14. A Comparison of the Australian Dietary Guidelines to the NOVA Classification System in Classifying Foods to Predict Energy Intakes and Body Mass Index
    Amanda Lee Grech, Anna Rangan, Margaret A Allman-Farinelli, Stephen James Simpson, Tim P. Gill, David Raubenheimer · 2022 · Nutrients
  15. Growth differentiation factor-15 is an IFN-γ regulated mediator of infection-induced weight loss and the hepatic FGF21 response
    Jojo Reyes, Yanlin Zhao, K. Pandya, George S. Yap · 2023 · Brain Behavior and Immunity
  16. Acute sleep loss alters circulating fibroblast growth factor 21 levels in humans: A randomised crossover trial
    Luiz Eduardo Mateus Brandão, Daniel Espes, Jakub Orzechowski Westholm, Teemu Martikainen, Nestori Westerlund, Lauri Lampola, Alexandru Popa, Heike Vogel, Annette Schürmann, Suzanne L. Dickson et al. · 2021 · Journal of Sleep Research
  17. Fibroblast growth factor 21 and dietary macronutrient intake in female mice
    Chih-Ting Wu, Karlton R. Larson, Michael L. Goodson, Karen Koeninger Ryan · 2022 · Physiology & Behavior
  18. Protein Restriction in Metabolic Health: Lessons from Rodent Models
    Khuhee Na, Yoon Jung Park · 2024 · Nutrients
  19. Effect of a 6-Week Carbohydrate-Reduced High-Protein Diet on Levels of FGF21 and GDF15 in People With Type 2 Diabetes
    Michael M. Richter, Mads Norvin Thomsen, Mads Juul Skytte, Sasha A. S. Kjeldsen, Amirsalar Samkani, Jan Frystyk, Faidon Magkos, Jens Juul Holst, Sten Madsbad, Thure Krarup et al. · 2024 · Journal of the Endocrine Society
  20. FGF21 as a mediator of adaptive changes in food intake and macronutrient preference in response to protein restriction
    Sora Q. Kim, Redin A. Spann, Md Shahjalal Hossain Khan, Hans‐Rudolf Berthoud, Heike Münzberg, Vance L. Albaugh, Yanlin He, David H. McDougal, Paul L. Soto, Sangho Yu et al. · 2024 · Neuropharmacology
  21. β-Klotho as novel therapeutic target in Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD): A narrative review
    Marica Meroni, Paola Dongiovanni, Francesca Tiano, Roberto Piciotti, Anna Alisi, Nadia Panera · 2024 · Biomedicine & Pharmacotherapy
  22. The Geometric Framework for Nutrition and Its Application to Rodent Models
    Alistair McNair Senior, David Raubenheimer, David George Le Couteur, Stephen J. Simpson · 2024 · Annual Review of Animal Biosciences
  23. Dynamic effects of dietary protein restriction on body weights, food consumption, and protein preference in C57BL /6J and Fgf21 ‐KO mice
    Francis Torres, Md Shahjalal Hossain Khan, Sun Ok Fernandez‐Kim, Redin A. Spann, Diana C. Albarado, Thomas J. Wagner, Christopher D. Morrison, Paul L. Soto · 2022 · Journal of the Experimental Analysis of Behavior
  24. Evidence for the protein leverage hypothesis in preschool children prone to obesity
    Hanyue Zhang, Alistair McNair Senior, Christoph C.S. Saner, Nanna Julie Olsen, Sofus Christian Larsen, Stephen James Simpson, David Raubenheimer, Berit L. Heitmann · 2023 · Clinical Nutrition
  25. Maternal macronutrient intake effects on offspring macronutrient targets and metabolism
    Therese Freire, Ximonie Clark, Tamara Pulpitel, Kim S. Bell-Anderson, Rosilene V. Ribeiro, David Raubenheimer, Angela J. Crean, Stephen James Simpson, Samantha M. Solon‐Biet · 2024 · Obesity
  26. Endocrine FGFs and their signaling in the brain: Relevance for energy homeostasis
    Lucas Zangerolamo, Marina Uchôa Wall Barbosa De Carvalho, Licio Augusto Velloso, Helena C.L. Barbosa · 2023 · European Journal of Pharmacology
  27. Short-term hypercaloric carbohydrate loading increases surgical stress resilience by inducing FGF21
    Thomas Agius, Raffaella Emsley, Arnaud Lyon, Michael Robert MacArthur, Kevin Kiesworo, Anna Faivre, Louis Stavart, Martine Lambelet, David Legouis, Sophie de Seigneux et al. · 2024 · Nature Communications
  28. The role of FGF21 in the interplay between obesity and non-alcoholic fatty liver disease: a narrative review
    Cristina Elena Negroiu, Iulia Tudorașcu, Maria Cristina Beznă, Adrian Ungureanu, Sorina Octavia Honţaru, Suzana Dănoiu · 2024 · Romanian Journal of Morphology and Embryology
  29. Dietary protein restriction diminishes sucrose reward and reduces sucrose-evoked mesolimbic dopamine signaling in mice
    Chih-Ting Wu, Diego Gonzalez Magaña, Jacob Roshgadol, Lin Tian, Karen Koeninger Ryan · 2024 · Appetite
  30. Distinct genetic signals at the FGF21 locus complicate studies of FGF21's role in diet regulation using human cohort data
    Stina Ramne, Mario García‐Ureña, Matthew Paul Gillum, Lars Henrik Ängquist, Torben Hansen, Jordi Merino, Niels Grarup · 2024 · Molecular Metabolism
  31. Periodic dietary restriction of animal products induces metabolic reprogramming in humans with effects on cardiometabolic health
    Konstantinos Rouskas, Ozvan Bocher, Alexandros Simistiras, Christina Emmanouil, Panagiotis Mantas, Anargyros Skoulakis, Young‐Chan Park, Alexandros C. Dimopoulos, Stavros Glentis, Gabi Kastenmüller et al. · 2025 · npj Metabolic Health and Disease
  32. Dietary isoleucine content modulates the metabolic and molecular response to a Western diet in mice
    Michaela E. Trautman, Cara L. Green, Michael Robert MacArthur, Krittisak Chaiyakul, Yasmine H. Alam, Chung‐Yang Yeh, Reji Babygirija, Isabella James, Michael Gilpin, Esther Zelenovskiy et al. · 2025 · Molecular Metabolism
  33. Testing the protein-leverage hypothesis using population surveillance data
    Alistair McNair Senior, David Raubenheimer, Stephen James Simpson · 2022 · Royal Society Open Science
  34. Mice Regulate Dietary Amino Acid Balance and Energy Intake by Selecting between Complementary Protein Sources
    Kamrul Zaman, Hee‐Chang Mun, Samantha M. Solon‐Biet, Alistair McNair Senior, David Raubenheimer, Stephen James Simpson, Arthur David Conigrave · 2024 · Journal of Nutrition
  35. Biology of Stress Responses in Aging
    Mariah F. Calubag, Ismail Ademi, Chung‐Yang Yeh, Reji Babygirija, Alyssa M. Bhoopat, Ildikó Kasza, Michelle M. Sonsalla, Cara L. Green, Heidi H. Pak, Dudley W. Lamming · 2023
  36. Lifelong restriction of dietary valine has sex-specific benefits for health and lifespan in mice
    Mariah F. Calubag, Ismail Ademi, Cara L. Green, Dulmalika N. H. Manchanayake, Hashan S. M. Jayarathne, Ryan N. Marshall, Sandra M. Le, Penelope Lialios, Lucia E. Breuer, Shoshana Yakar et al. · 2026 · Nature Aging
  37. In Vivo Electrochemical Aptasensors Reveal Reversible Dopamine Dysregulation from Adolescent Malnutrition
    Pengwei Li, Qijia Ma, Fenghui Zhu, Kaixin Song, Yinghuan Liu, Ying Yan Jiang, Lanqun Mao · 2025 · ACS Sensors
  38. The paradox of plant preference: The malaria vectors Anopheles gambiae and Anopheles coluzzii select suboptimal food sources for their survival and reproduction
    Prisca S. L. Paré, Domonbabélé François de Sales Hien, Mariam Youba, Rakiswendé Serge Yerbanga, Anna Cohuet, Louis‐Clément Gouagna, Abdoulaye Diabaté, Rickard Ignell, Roch K. Dabiré, Olivier Gnankiné et al. · 2024 · Ecology and Evolution
  39. Dietary Essential Amino Acid Restriction Promotes Hyperdipsia via Hepatic FGF21
    Patricia M. Rusu, Andrea Y. Chan, Mathias F Heikenwälder, Oliver Josef Müller, Adam J. Rose · 2021 · Nutrients
  40. Effects of Dietary Protein Intake Levels on Peripheral Circadian Rhythm in Mice
    Yerim Han, Jinyoung Shon, So Young Kwon, Yoon Jung Park · 2024 · International Journal of Molecular Sciences
  41. Dietary protein restriction modulates ‘dessert’ intake after a meal, via fibroblast growth factor 21 (FGF21)
    Chih-Ting Wu, Karlton R. Larson, Landon C. Sims, Karen Koeninger Ryan · 2023 · Physiology & Behavior
  42. Hepatic fibroblast growth factor 21 is required for curcumin or resveratrol in exerting their metabolic beneficial effect in male mice
    Jia Nuo Feng, Weijuan Shao, Lin Yang, Juan Pang, Wenhua Ling, Dinghui Liu, Michael B. Wheeler, Housheng Hansen He, Tianru Jin · 2025 · Nutrition and Diabetes
  43. Rats Self-Select a Constant Protein-to-Carbohydrate Ratio Rather Than a Constant Protein-to-Energy Ratio and Have Low Plasma FGF21 Concentrations
    Joséphine Gehring, Dalila Azzout‐Marniche, Catherine Chaumontet, Julien Piedcoq, Claire Gaudichon, Patrick C. Even · 2021 · Journal of Nutrition
  44. Metabogenomic analysis to functionally annotate the regulatory role of long non-coding RNAs in the liver of cows with different nutrient partitioning phenotype
    Wietje Nolte, Rosemarie Weikard, Elke Albrecht, Harald Michael Hammon, Christa Kühn · 2021 · Genomics
  45. Estradiol-dependent and independent effects of FGF21 in obese female mice
    T. V. Jakovleva, A. Yu. Kazantseva, A. D. Dubinina, N. Yu. Balybina, Konstantin O. Baranov, E. N. Makarova, Н. М. Бажан · 2022 · Vavilov Journal of Genetics and Breeding
  46. Complex interplay of neuronal and hormonal gut-brain responses to essential amino acid deficit
    Boram Kim, Seongju Lee, Hyeyeon Bae, S R Kim, Jong-Hoon Won, Dongwoo Kim, Byung-Kwon Jung, Makoto I. Kanai, Sung‐Eun Yoon, Yangkyun Oh et al. · 2026 · Science
  47. Intermittent protein restriction elevates food intake and plasma ghrelin in male mice
    K. Linnea Volcko, Hamid Taghipourbibalan, James E. McCutcheon · 2024 · Appetite
  48. Autophagy-related 7 (ATG7) regulates food intake and liver health during asparaginase exposure
    Brian A. Zalma, Maria Ibrahim, Flavio C. Rodriguez-Polanco, Chintan T. Bhavsar, Esther M. Rodriguez, Eduardo Cararo Lopes, Saad A. Farooq, Jordan L. Levy, Ronald C. Wek, Eileen White et al. · 2025 · Journal of Biological Chemistry
  49. Dietary protein restriction in rats leads to a rapid within-session preference for protein
    Giulia Chiacchierini, Fabien Naneix, John Apergis‐Schoute, James E. McCutcheon · 2025 · Physiology & Behavior
  50. FGF21 analogue PF-05231023 on alcohol consumption and neuronal activity in the nucleus accumbens
    Bart J. Cooley, C. Brown, Eun Ah Choi, Willow A. Heller, A LIM, Andrew John Lawrence, Paul Haber, Gavan P. McNally, E. Zayra Millan · 2025 · Neuropsychopharmacology
  51. Context matters for addressing controversies in FGF21 biology
    Chih-Ting Wu, Karen Koeninger Ryan · 2024 · Trends in Endocrinology and Metabolism
  52. Exercise, spinogenesis and cognitive functions
    Li Zhang, Kwok‐Fai So · 2019 · International review of neurobiology
  53. Protein-carbohydrate interaction effects on energy balance, FGF21, IGF-1, and hypothalamic gene expression in rats
    Joséphine Gehring, Dalila Azzout‐Marniche, Catherine Chaumontet, Julien Piedcoq, Claire Gaudichon, Patrick C. Even · 2021 · American Journal of Physiology-Endocrinology and Metabolism
  54. In vivo antidiabetic activity of nimesulide due to inhibition of amino acid transport
    Amit Arvind Joharapurkar, Samadhan Govind Kshirsagar, VISHAL G. PATEL, Maulik S. Patel, Hardikkumar H. Savsani, Mukul Rameshchandra Jain · 2021 · Basic & Clinical Pharmacology & Toxicology
  55. The role of FGF21 in the metabolic adjustments required for exercise capacity
    Abe, Lisa, Dantzer, Robert · 2025 · Life Sciences
  56. Dietary macronutrient content and energy intake in the mouse: hedonic or homeostatic override?
    Stephen James Simpson, Alistair McNair Senior, Samantha M. Solon‐Biet, David George Le Couteur, David Raubenheimer · 2025 · Obesity
  57. Childhood Malnutrition and Association of Lean Mass with Metabolome and Hormone Profile in Later Life
    Gerard Bryan Gonzales, Natasha Lelijveld, Céline Bourdon, Emmanuel Chimwezi, Moffat Nyirenda, Jonathan C. K. Wells, Marko Kerac, Robert Bandsma · 2020 · Nutrients
  58. Higher fasting plasma FGF21 concentration is associated with lower ad libitum soda consumption in humans
    Alessio Basolo, Tim Hollstein, Mujtaba H. Shah, Mary F. Walter, Jonathan A. Krakoff, Susanne B. Votruba, Paolo Piaggi · 2021 · American Journal of Clinical Nutrition
  59. The limitations of investigating appetite through circuit manipulations: are we biting off more than we can chew?
    Joshua Wang, Kate Beecher, Fatemeh Chehrehasa, Hayley Moody · 2022 · Reviews in the Neurosciences
  60. Glibenclamide promotes FGF21 secretion in interscapular BAT and attenuates depression-like behaviors in male mice with HFD-induced obesity
    Yi‐Ying Kuo, Hao-Yeh Tsai, Yu‐Min Kuo, Shun‐Fen Tzeng, Po-See Chen, Po‐Hung Hsu, Ya‐Tin Lin, Pei‐Chun Chen · 2023 · Life Sciences
  61. Secreted proteins in treating metabolic dysfunction-associated steatotic liver disease: from bench towards bedside
    Yeping Huang, Bin Liu, Cheng Hu, Yan Lu · 2025 · Protein & Cell
  62. Brain amino acid sensing for organismal amino acid homeostasis
    Anthony H. K. Tsang, Liubou Samson, Clémence Blouet · 2025 · Open Biology
  63. The hallmarks of protein and amino acid restriction in aging and longevity
    Bailey A. Knopf, Dudley W. Lamming · 2026 · Cell Press Blue
  64. Deletion of GFRAL blunts weight lowering effects of FGF21 in female mice
    Alberte Silke Buch-Rasmussen, Helle Andersen, Christina Stage, Ann Maria Kruse Hansen, Sarah Juel Paulsen, Matthew Paul Gillum, Birgitte Andersen, Anna Secher, Markus Robert Latta, Christoffer Clemmensen et al. · 2025 · Journal of Endocrinology
  65. Does the lateral hypothalamus govern the transition between appetitive and consummatory feeding?
    Mette Kongstorp, Mahesh Karnani, James E. McCutcheon · 2025 · Neuropharmacology
  66. Metabolism in the Midwest: research from the Midwest Aging Consortium at the 49th Annual Meeting of the American Aging Association
    Michaela E. Trautman, Akilavalli Narasimhan, Alexis E. Adrian, Ankur Kumar, Cara L. Green, Carolina Soto-Palma, Chathurika Henpita, Christina D. Camell, Christopher S. Morrow, Chung‐Yang Yeh et al. · 2021 · GeroScience
  67. FGF-21 Conducts a Liver-Brain-Kidney Axis to Promote Renal Cell Carcinoma
    Zongyu Li, Xinyi Zhang, Wanling Zhu, Cuiling Zhang, Katherine Sadak, Alexandra A. Halberstam, Jason Robert Brown, Curtis J. Perry, Azia Bunn, David A. Braun et al. · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
  68. Low protein-induced-FGF-21 signaling remodels adipose tissue on reduced markers of senescence during aging
    José A. Godoy-Lugo, Khristina E. Young, Prerana Vaddi, Yvann Batamack, Jolaiya Aldridge, Sun Ok Fernandez‐Kim, Diana C. Albarado, Susan J. Burke, Jacqueline M. Stephens, Christopher D. Morrison et al. · 2025 · GeroScience
  69. Angiogenesis-independent VEGF signaling enhances exercise capacity by increasing fat oxidation in mice fed sulfur amino acid-restricted diets
    Charlotte G. Mann, Michael Robert MacArthur, Jing Zhang, Songlin Gong, Jenna E. AbuSalim, Craig J. Hunter, Wenyun Lu, Thomas Agius, Alban Longchamp, Florent Allagnat et al. · 2025 · iScience
  70. FGF21 signals through hindbrain neurons to alter food intake and energy expenditure during dietary protein restriction
    Redin A. Spann, Sora Q. Kim, Md Shahjalal Hossain Khan, Diana A Albarado, Sun Ok Fernandez‐Kim, Hans‐Rudolf Berthoud, David H. McDougal, Heike Münzberg, Yanlin He, Sangho Yu et al. · 2026 · Cell Reports
  71. Protein Decoys, Alcohol, and Energy Intake: Testing a Mechanistic‐Ecological Model
    Amanda Lee Grech, Stephen J. Simpson, David Raubenheimer · 2026 · Obesity Reviews
  72. Calcium-Sensing Receptors Mediate Amino Acid Signals From the Liver to Islet Alpha Cells
    Arthur David Conigrave, Stephen James Simpson · 2023 · The Journal of Clinical Endocrinology & Metabolism
  73. Ecology, Protein Leverage, and Public Health
    David Raubenheimer, Stephen James Simpson · 2022
  74. Targeted cravings: Unraveling the drivers of nutrient-specific appetite
    Clare E. Hancock, Binod Aryal, Tianji Ma, Guangyan Wu, Qili Liu · 2025 · Current Opinion in Neurobiology
  75. Identifying genetic variants associated with sugar intake and appraising the genetic correlations with cardiovascular outcomes
    Suzanne Janzi, Stina Ramne, Minghao Kou, Xinmei Lu, Anna Stubbendorff, Chaofu Ke, Yan Borné, Lu Qi, Emily Sonestedt · 2025 · Clinical Nutrition
  76. Muscle-to-CNS signaling in physiological homeostasis, aging, and disease
    Chia-Lung Chuang, Mamta Rai, Fabio Demontis · 2026 · Trends in Molecular Medicine
  77. Protein supplementation in South Korea: balancing physiological benefits and metabolic risks for evidence-based guidelines
    Kyung Won Lee, Sangwon Chung, Eunjung Kim, Yoon Jung Park, Kyungho Ha · 2026 · Journal of Nutrition and Health
  78. Lack of single amino acids transcriptionally tunes sensory systems to enhance microbiota intake
    Gili Ezra-Nevo, Sílvia F. Henriques, Daniel Münch, Ana Patrícia Francisco, Célia Baltazar, Ana Paula Elias, Bart Deplancke, Carlos Ribeiro · 2025 · Current Biology
  79. Protein appetite drives macronutrient-related differences in ventral tegmental area neural activity
    G Chiacchierini (21471335), F Naneix (8373876), Kate Zara Peters, J Apergis-Schoute (7733501), EMS Snoeren (21471338), JE McCutcheon (8373882) · 2025 · Figshare
  80. Plasma FGF21 concentrations and spontaneous self-selection of protein suggest that 15% protein in the diet may not be enough for male adult rats
    Joséphine Gehring, Dalila Azzout‐Marniche, Catherine Chaumontet, Claire Gaudichon, Patrick C. Even · 2021 · American Journal of Physiology-Endocrinology and Metabolism
  81. Meal-to-meal and day-to-day macronutrient variation in an ad libitum vending food paradigm
    Tomás Cabeza de Baca, Paolo Piaggi, Marci E. Gluck, Jonathan A. Krakoff, Susanne B. Votruba · 2022 · Appetite
  82. Liver Fibroblast Growth Factor 21 (FGF21) is Required for the Full Anorectic Effect of the Glucagon-Like Peptide-1 Receptor Agonist Liraglutide in Male Mice fed High Carbohydrate Diets
    Thao D. V. Le, Payam A. Fathi, Amanda B. Watters, Blair J. Ellis, Nadejda Bozadjieva-Kramer, Misty B. Perez, Andrew I. Sullivan, Jesse P. Rose, Laurie L. Baggio, Jacqueline A. Koehler et al. · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
  83. Persistent Behavioral and Physiological Effects of Dietary Protein Restriction
    Paul L. Soto, Christopher D. Morrison · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
  84. Dietary Insulinogenic Amino Acid Restriction Improves Glucose Metabolism in a Neonatal Piglet Model
    Matthew W Gorton, Parniyan Goodarzi, Xia Lei, Michael C. Anderson, Mohammad Habibi, Nedra F. Wilson, Adel Pezeshki · 2025 · Nutrients
  85. The brain-eye-liver axis during spaceflight: implications of hepatic dysfunction in spaceflight associated neuro-ocular syndrome
    Sinem Helvacıoğlu, Ben Cools, Joshua Ong, Ethan Waisberg, Ryung S. Lee, Andrew G. Lee, Mathieu Vinken · 2025 · Life Sciences in Space Research
  86. Deoxycholic acid derived from the gut microbiota involved in the regulation of adaptive thermogenesis in response to dietary protein restriction in plateau pika
    Fuyu Shi, Zhiteng Yang, Liangzhi Zhang, Desheng Zou, Jiangkun Yu, Na Guo, Shien Ren, Xianjiang Tang, Chen Juan Gu, Ruiping Xu et al. · 2025 · Microbiome
  87. Vagal sensory neurons encode internal protein status to guide eating
    M. Yang, Alan de Araujo, J Shakir, I. Braga, Rebeca Méndez‐Hernández, Gabriel S. S. Tofani, A. Bali, J de Lartigue, H. Song, James E. McCutcheon et al. · 2025 · Molecular Metabolism
  88. Development of a severe rat refeeding syndrome model and mathematical modeling of the associated hypophosphatemia
    Hiroaki Kato, Ippei Yamaoka, Hiroyuki Kubota · 2026 · npj Systems Biology and Applications
  89. The liver-brain axis, from its function to preventive therapeutic strategies in diseases
    Yuehua Chen, Shangcheng Xu, Tao Sun · 2026 · Frontiers in Endocrinology
  90. Fibroblast Growth Factor 21: Possible Role in Growth and Metabolic Development during Early Life, Nutritional Interactions and Biological Actions
    Jibran A. Wali, Jose M Ramos-Nieves, Aristea Binia, Eline M. van der Beek · 2026 · Advances in Nutrition
  91. Characterizing substrate utilization during the fasted state using plasma high-resolution metabolomics
    Kaitlin R. Taibl, Moriah P. Bellissimo, Matthew Ryan Smith, Ken Liu, ViLinh Tran, Dean P. Jones, Thomas R. Ziegler, Jessica A. Alvarez · 2023 · Nutrition
  92. Intercepting Modes of Cellular Communication
    Kristin E. Claflin, Matthew J. Potthoff · 2025 · Cellular and Molecular Gastroenterology and Hepatology
  93. The Metabolic Effects of FGF21: From Physiology to Pharmacology
    Parkyong Song · 2020 · JoLS Journal of Life Sciences
  94. Proceedings from the annual University of Washington Geroscience Symposium, October 23, 2020
    Mitchell B. Lee, Alessandro Bitto, Matt R. Kaeberlein · 2021 · GeroScience
  95. Protein appetite drives macronutrient-related differences in ventral tegmental area neural activity
    Giulia Chiacchierini, Fabien Naneix, Kate Zara Peters, John Apergis-Schoute, Eelke Mirthe Simone Snoeren, James E. McCutcheon · 2019 · bioRxiv (Cold Spring Harbor Laboratory)
  96. Age dependent effects of protein restriction on dopamine release
    Fabien Naneix, Kate Zara Peters, Andrew M. J. Young, James E. McCutcheon · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
  97. Fibroblast growth factor-21 induces skeletal muscle atrophy and increases plasma amino acids in female mice: a potential role for glucocorticoids
    Karlton R. Larson, Devi Jayakrishnan, Karla A. Soto Sauza, Michael L. Goodson, AKI T.B. CHAFFIN, Arik Davidyan, Suraj J. Pathak, Yanbin Fang, Diego Gonzalez Magaña, Benjamin F. Miller et al. · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
  98. Periodic dietary restriction of animal products induces metabolic reprogramming in humans with effects on health
    Konstantinos Rouskas, Ozvan Bocher, Alexandros Simistiras, Christina Emmanouil, Panagiotis Mantas, Anargyros Skoulakis, Y.C. Park, Alexandros C. Dimopoulos, Stavros Glentis, Gabi Kastenmüller et al. · 2024 · medRxiv
  99. Dietary protein restriction diminishes sucrose reward and reduces sucrose-evoked mesolimbic dopamine signaling
    Chih-Ting Wu, Diego Gonzalez Magaña, Jacob Roshgadol, Lin Tian, Karen Koeninger Ryan · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
  100. FGF21 signals through KLB-expressing glutamatergic neurons in the hindbrain to mediate the effects of dietary protein restriction
    Redin A. Spann, Sora Q. Kim, Md Shahjalal Hossain Khan, Diana A Albarado, Sun Ok Fernandez‐Kim, Hans‐Rudolf Berthoud, David H. McDougal, Heike Münzberg, Yanlin He, Sangho Yu et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)