Brain Endothelial Cells Are Exquisite Sensors of Age-Related Circulatory Cues

Cited by (238)

Items 201–238 of 238

1. MPS for Blood Brain Barrier
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2. Additional file 4 of Aged microglia promote peripheral T cell infiltration by reprogramming the microenvironment of neurogenic niches
   Xiaotao Zhang, Rui Wang, Chen, Haoran, Cheng‐Hao Jin, Ziyang Jin, Jianan Lü, Liang Xu, Yunrong Lu, Jianmin Zhang, Ligen Shi · 2022 · Figshare
3. Additional file 6 of Aged microglia promote peripheral T cell infiltration by reprogramming the microenvironment of neurogenic niches
   Xiaotao Zhang, Rui Wang, Chen, Haoran, Cheng‐Hao Jin, Ziyang Jin, Jianan Lü, Liang Xu, Yunrong Lu, Jianmin Zhang, Ligen Shi · 2022 · Figshare
4. Additional file 2 of Aged microglia promote peripheral T cell infiltration by reprogramming the microenvironment of neurogenic niches
   Xiaotao Zhang, Rui Wang, Chen, Haoran, Cheng‐Hao Jin, Ziyang Jin, Jianan Lü, Liang Xu, Yunrong Lu, Jianmin Zhang, Ligen Shi · 2022 · Figshare
5. Additional file 3 of Aged microglia promote peripheral T cell infiltration by reprogramming the microenvironment of neurogenic niches
   Xiaotao Zhang, Rui Wang, Chen, Haoran, Cheng‐Hao Jin, Ziyang Jin, Jianan Lü, Liang Xu, Yunrong Lu, Jianmin Zhang, Ligen Shi · 2022 · Figshare
6. Additional file 5 of Aged microglia promote peripheral T cell infiltration by reprogramming the microenvironment of neurogenic niches
   Xiaotao Zhang, Rui Wang, Chen, Haoran, Cheng‐Hao Jin, Ziyang Jin, Jianan Lü, Liang Xu, Yunrong Lu, Jianmin Zhang, Ligen Shi · 2022 · Figshare
7. Neuroinflammation Induces Myelin Damage by Inhibiting Gapdh of Oligodendrocytes in the Hippocampus
   Zhongjia Li, Huiqun Fu, Fangyan Liu, Yan Wu, Tianlong Wang · 2024 · Research Square
8. Effect of aging and Varroa parasitism on the paracellular and transcellular permeability of the honeybee blood-brain barrier
   Tyler P. Quigley, Gro Vang Amdam · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
9. Single-cell profiling reveals a novel RAB13+ endothelial subpopulation and profibrotic mesenchymal cells in the aged human bone marrow
   Itziar Cenzano, Miguel Cócera, Ana Rosa Lopez-Perez, Lorea Campos‐Dopazo, Javier Ruiz, Ignacio Sancho, Patxi San Martín‐Úriz, Paula Aguirre‐Ruiz, Sarai Sarvide, Amaia Vilas‐Zornoza et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
10. Chronic β3 adrenergic agonist treatment improves neurovascular coupling responses, attenuates blood-brain barrier leakage and neuroinflammation, and enhances cognition in aged mice
    Natarajan Duraipandy, Shoba Ekambaram, Stefano Tarantini, Raghavendra Yelahanka Nagaraja, Andriy Yabluchanskiy, Andria F. Hedrick, Vibhudutta Awasthi, Madhan Subramanian, Anna Csiszár, Priya Balasubramanian · 2025 · Aging
11. Gα q/11 signalling counteracts endothelial dysfunction in the brain and protects cognition in aged mice
    Dimitrios Spyropoulos, Lena Kleindienst, Phillip Ehrich, Dorothea Ziemens, Rentsenkhand Natsagdorj, Nicholas Noll, Cathrin Elly Hansen, Géza Adam Curley, Anne-Sophie Gutt, Ákos Menyhárt et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
12. Early endothelial activation at the blood–nerve barrier defines a hallmark of ALS
    Ganesh Parameshwar Bhat, Santo Diprima, Cristian G. Beccaría, Paola Podini, Aurora Badaloni, Alessia Motta, Ilaria Brambilla, Luís F. Martins, Daniela Boselli, Stefano de Pretis et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
13. Targeting Endothelial KDM5A to Attenuate Aging and Ameliorate Age‐Associated Metabolic Abnormalities
    Rifeng Gao, Li-Feng Liang, Ling Yang, Chunyu Lyu, Yang Lyu, Wei-Jun Yang, Jia-Ran Shi, Wei Wei, Jia-Hui Cheng, Xiao-Lei Sun et al. · 2025 · Advancement of science
14. Single-cell transcriptomic analysis reveals age-related remodeling of brain endothelial cells
    Hai Duc Nguyen, Summer Siddiqui, Diana G. Bohannon, Robert V. Blair, Hong-Wen Deng, Alexandre Prat, Woong-ki Kim · 2026 · Aging Brain
15. Additional file 1 of Reduction in pericyte coverage leads to blood–brain barrier dysfunction via endothelial transcytosis following chronic cerebral hypoperfusion
    Sun, Zhengyu, Gao, Chenhao, Gao, Dandan, Ruihua Sun, Li, Wei, Wang, Fengyu, Wang, Yanliang, Huixia Cao, Zhou, Guoyu, Jiewen Zhang et al. · 2021 · Figshare
16. Additional file 1 of Aged microglia promote peripheral T cell infiltration by reprogramming the microenvironment of neurogenic niches
    Zhang, Xiaotao, Wang, Rui, Chen, Haoran, Jin, Chenghao, Jin, Ziyang, Jianan Lü, Xu, Liang, Yunrong Lu, Zhang, Jianmin, Shi, Ligen · 2022 · Figshare
17. Additional file 1 of Serum biomarkers of neuroinflammation and blood-brain barrier leakage in amyotrophic lateral sclerosis
    Maize C. Cao, Erin E. Cawston, Grace Xia Chen, Collin Brooks, Jeroen E. Douwes, Dave McLean, E. Scott Graham, Dragunow, Mike, Emma L. Scotter · 2022 · Figshare
18. Th17 effector cytokines induce shared and distinct microglial and endothelial cell responses in post-streptococcal encephalitis
    Charlotte R. Wayne, Uğur Akcan, Travis E. Faust, Violeta Durán-Laforet, Danny Jamoul, Luca Bremner, Nicole Ampatey, Busra Turan Akcan, Sarah J. Ho, Bogoljub Ćirić et al. · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
19. Mutations associated with Alzheimer’s disease and aged serum synergistically elicit blood-brain barrier dysfunction in a tissue-engineered model
    Tracy D. Chung, Lily Rui Liang, Linus Wang, Elizabeth G. Kim, Sukriti Gupta, Ikshu Pandey, Peter C. Searson · 2026 · Fluids and Barriers of the CNS
20. The ISG15 axis: a central mediator and therapeutic target in vascular inflammaging
    Ziwei Fang, Shuyi Nie, Hualin Chen, Chenxin Deng, Cuntai Zhang, Le Zhang · 2026 · The Journals of Gerontology Series A
21. Single‐Cell Profiling Reveals RAB13 + Endothelial Cells and Profibrotic Mesenchymal Cells in Aged Human Bone Marrow
    Itziar Cenzano, Miguel Cócera, Ana Rosa López-Pérez, Lorea Campos‐Dopazo, Javier Ruiz, Ignacio Sancho, Patxi San Martín‐Úriz, Paula Aguirre‐Ruiz, Sarai Sarvide, Amaia Vilas‐Zornoza et al. · 2026 · Aging Cell
22. Endothelial energy failure as a therapeutic target in elderly strokes
    Sanaz Nasoohi, Farehe Ebrahimi, Candice M. Brown, Jason Delwyn Huber · 2026 · Journal of Cerebral Blood Flow & Metabolism
23. Leukocyte–endothelial interactions and brain capillary function in neurological diseases
    Hyun‐Kyoung Lim, Andy Y. Shih, Juliane Gust · 2026 · Journal of Cerebral Blood Flow & Metabolism
24. Brain endothelial Gαq/11 signalling in cerebrovascular function and cognition of aged mice
    Dimitrios Spyropoulos, Lena Kleindienst, Phillip Ehrich, Dorothea Ziemens, Rentsenkhand Natsagdorj, Nicholas Noll, Cathrin Elly Hansen, Géza Adam Curley, Anne-Sophie Gutt, Ákos Menyhárt et al. · 2026 · EBioMedicine
25. Transcriptional analyses identify pericyte-centered signaling programs altered by sex and brain region in Alzheimer’s Disease
    Kareem El‐Ghazawi, Yonathan Tamrat Aberra, Yashasvisai Veeramasu, Wisam A. Fares, Brant E. Isakson, Harald W. Sontheimer, Ukpong B. Eyo, SHAYN M. PEIRCE · 2026 · Communications Biology
26. Endothelial KLF4 depletion drives age-related neurovascular dysfunction and neuropsychiatric impairment
    Matasha Dhar, Edwin Vázquez‐Rosa, Kalyani Chaubey, Emiko Miller, Sofia G. Corella, Suwarna Chakraborty, Sunil Jamuna Tripathi, Tapatee Das, Xudong Liao, Mohamed Alkassem Alosman et al. · 2026 · Proceedings of the National Academy of Sciences
27. Integrated single-cell and Mendelian randomization analyses identify aging-induced brain endothelial SPARCL1 deficiency as a key driver of vascular dementia
    Jiancheng Jin, Qiu-Han Xu, Guotao Peng, Jiankuai Zhou, Yuchun Liu, 莫君 · 2026 · Experimental Gerontology
28. Single-cell RNA sequencing of organ-specific endothelial landscapes and intercellular networks in endocrine organs
    Yoo Hyung Kim, Jaewoo Mo, Dong Hwa Choi, Yea Eun Kang, Sun Wook Cho, Young Joo Park, Junil Kim · 2026 · Research Square
29. What Is the Role of Endothelial Cells in Cerebral Blood Flow Dysregulation in Small Vessel Disease?
    Eduardo Elias Benarroch · 2026 · Neurology
30. Inhibiting the Endothelial Mechanosensitive Channel Piezo1 Restores Hippocampal Blood–Brain Barrier Integrity to Improve Anesthesia‐ and Surgery‐Induced Cognitive Decline
    Yong Qiu, Chunheng Mo, Jinyan Wu, Jiachen Li, Shiyu Xu, Lu Chen, Liyin Zhang, Xingming Huang, Yi Zhang, Meng Sun et al. · 2026 · MedComm
31. Blood Pressure Variability and Alzheimer Disease Biomarkers
    Trevor Lohman, Isabel J. Sible, Yuan Ma, Niema M. Pahlevan, Daniel A. Nation · 2026 · Hypertension
32. Neurodegeneration as a dysregulation of neuroimmune crosstalk
    F. Chris Bennett, Soyon Youngae Hong, Ning Jenny Jiang, Ivan Marazzi · 2026 · Cell
33. VINE-seq and MultiVINE-seq for single-nucleus and multiome profiling of the brain vasculature
    Jane Oberhauser, Bella Ding, Madigan M. Reid, William H. Xie, Andrew C. Yang · 2026 · Nature Protocols
34. A meta-interaction basis for cell-cell communication in tissues
    Junjie Tang, Shaoheng Liang, Shahul Alam, Wenduo Cheng, Yang Zhang, Jian Ma · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
35. Immune-endothelial crosstalk at the nexus of neuroinflammation and vascular dysfunction in aging
    Zhitao Cui, Huaiyu Sun, Zhiqing Chen, Jiaai Li · 2026 · Frontiers in Immunology
36. StrokeTime: A comprehensive longitudinal scRNA-seq atlas of the ischemic mouse brain
    Josef Anrather, Lidia García‐Bonilla · 2026 · iScience
37. Modified Dioscorea pills ameliorate cognitive impairment induced by chronic cerebral hypoperfusion via restoring the hippocampal neurovascular unit
    Qian Xu, Dan He, Hongbing Li · 2026 · Frontiers in Medicine
38. Uncovering the transcriptional hallmarks of endothelial cell aging via integrated single-cell analysis
    Sarah Dobner, Lisa Kleißl, Fanni Tóth, Robert L. Paxton, Irena Yordanova, Kveta Brazdilova, Cedric Vanluyten, Aleksandra Aizenshtadt, Hanna Tóth, Jake Burton et al. · 2026 · Nature Aging