Neurotoxic Reactive Astrocytes Drive Neuronal Death after Retinal Injury

Guttenplan, Kevin A., Stafford, Benjamin K., El-Danaf, Rana N., Adler, Drew I., Münch, Alexandra E., Weigel, Maya K., Huberman, Andrew D., Liddelow, Shane A.·2020·Cell Reports

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  8. IL-1–mediated vitreous inflammation as an early indicator of retinal ganglion cell loss following acute optic nerve injury
    Shichu Chang, Weijia Fan, Jia-Hui Wu, Lei Xu, Virginia A Lee, Charlotte Zhang, Edward P. Kronenberg, Wenjing Xu, Hu Yang, Hao F. Zhang et al. · 2026 · Journal of Neuroinflammation
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    Adam J. Schuller, Abigail M. Bibb, Megan R. Hager, Omar A. Yanouri, Emma J. Smith, Aidan M. Briggs, Luke B. Montrose, Ronald B. Tjalkens · 2026 · NeuroToxicology
  10. Fibrin hydrogels regulate human astrocyte state and neuronal reprogramming
    Thomas Distler, Katherina Konrad Daga, Martina Bürkle, Sebastián Vásquez-Sepúlveda, Kristian Franze, Magdalena Götz, Giacomo Masserdotti · 2026 · Cell Biomaterials
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  15. The Dual Role of Macroglia in Glaucoma: Deciphering the Contributions of Astrocytes and Müller Cells to Retinal Neurodegeneration and Neuroprotection
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  16. C1q dependency of retinal ganglion cell death in blast-mediated traumatic brain injury
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  17. Aging limits neuronal regeneration from glia in the mouse retina
    Jugasmita Deka, Ying Han, Sucheta Bhattacharya, Samantha Sutton, Galina Bachay, William J. Brunken, Levi J. Todd · 2026 · Proceedings of the National Academy of Sciences
  18. Primary Cilia of Astrocytes in the Retina in Development and Disease
    Ke Ning, Matthew Tran, Xin Xia, Tia J. Kowal, Qing Kenneth Wang, Chien‐Hui Lo, Siyu Chen, Zhiquan Liu, Tingting Li, Fan Zhang et al. · 2026 · Investigative Ophthalmology & Visual Science
  19. Activated olfactory ensheathing cells suppress astrocyte reactivity and CSPGs expression through IL-10 signaling in an in vitro scratch-injury model of glial scarring
    Dandan Zhang, Xiaoyu Ma, Zijian Liu, WenXin Su, Junping Li, Hao Yang · 2026 · Brain Research
  20. Therapeutic AIBP expression contributes to synaptic preservation and vision restoration against glaucomatous neuroinflammation
    Tonking Bastola, Sinwoo Hwang, Ziyao Shen, Soo-Ho Choi, Seunghwan Choi, Esther Jang, Muna Poudel, Keun-Young Kim, Yury I. Miller, Robert Neal Weinreb et al. · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
  21. Glaucoma neurodegeneration: targeted modulation of intraocular immune pathways – a review of novel therapeutic advances
    Yunyun Sun, Keyun Xue, Congqin Wen, Xinyan Ma, Xiaojie Hu · 2026 · Frontiers in Immunology