The DOI matches its Crossref record; 9 of the 9 references it cites were found in a registry or an index.
QuickStroop Predicts Time to Development of Overt Hepatic Encephalopathy and Related Hospitalizations in Patients With Cirrhosis
Open accessAbstract
Cirrhosis-related neurocognitive impairment caused by covert or minimal hepatic encephalopathy (CHE) affects psychosocial function, increases risk of overt hepatic encephalopathy (OHE) development, and worsens survival.1,2 However, detection in clinical practice is challenging.2 One modality used for screening and prediction of outcomes related to cirrhosis is the EncephalApp Stroop, but it can require up to 10 minutes. Furthermore, the assessment comprises of distinct stages of difficulty, with an easier "Off" stage and a more challenging "On" stage.3 To alleviate these concerns, QuickStroop, which takes <1 minute, was developed. This uses only the first 2 runs of the Off stage of the EncephalApp Stroop, where number signs presented in red, green, or blue need to be matched quickly to their respective colors.4 A prior study showed these versions were comparable cross-sectionally to diagnose CHE.4 However, the utility of QuickStroop to predict cirrhosis-related outcomes is unclear.5-7 Our aim was to determine the ability of QuickStroop to determine time to development of OHE and OHE-related hospitalizations, all-cause hospitalizations, and death in outpatients with cirrhosis.
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QuickStroop can help predict the development of overt HE, hospitalization, and death.
“QuickStroop, a test that takes <1 minute to apply, can help predict the development of overt HE, hospitalization, and death.13”
From Management of depression/anxiety in patients with chronic liver disease (2024) · cites this paper as [13]
The Abstract reports that QuickStroop takes less than one minute and that its results remained significantly associated with overt HE development and overt HE-related hospitalizations after adjustment. The discussion section beginning “However, the initial association…” says the associations with all-cause hospitalization and mortality did not persist after adjustment. Thus the unqualified claim about predicting hospitalization and death overstates the findings. (LLM, conf=0.91)
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Cites
Vilstrup, H., Amodio, P., Bajaj, J. S., Córdoba, J., Ferenci, P., Mullen, K. D., Weißenborn, K., & Wong, P. Y. N. (2014) · Hepatology · doi:10.1002/hep.27210 · Cited by 2,065
Self-citationNeuropsychological characterization of hepatic encephalopathy
Weißenborn, K., Ennen, J. C., Schomerus, H., Rückert, N., & Hecker, H. (2001) · Journal of Hepatology · doi:10.1016/s0168-8278(01)00026-5 · Cited by 796
Prognostic significance of hepatic encephalopathy in patients with cirrhosis
Bustamante, J., Rimola, A., Ventura, P., Navasa, M., Cirera, I., Reggiardo, V., & Rodés, J. (1999) · Journal of Hepatology · doi:10.1016/s0168-8278(99)80144-5 · Cited by 565
Bajaj, J. S., Córdoba, J., Mullen, K., Amodio, P., Shawcross, D. L., Butterworth, R. F., & Morgan, M. Y. (2011) · Alimentary Pharmacology & Therapeutics · doi:10.1111/j.1365-2036.2011.04590.x · Cited by 349
Self-citationThe animal naming test: An easy tool for the assessment of hepatic encephalopathy
Campagna, F., Montagnese, S., Ridola, L., Senzolo, M., Schiff, S., Rui, M. D., Pasquale, C., Nardelli, S., Pentassuglio, I., Merkel, C., et al. (2017) · Hepatology · doi:10.1002/hep.29146 · Cited by 204
Patidar, K. R., Thacker, L. R., Wade, J. B., Sterling, R. K., Sanyal, A. J., Siddiqui, M. S., Matherly, S. C., Stravitz, R. T., Puri, P., Luketic, V. A., et al. (2014) · The American Journal of Gastroenterology · doi:10.1038/ajg.2014.264 · Cited by 195
Self-citationAllampati, S., Duarte‐Rojo, A., Thacker, L. R., Patidar, K. R., White, M. B., Klair, J. S., John, B. V., Heuman, D. M., Wade, J. B., Flud, C. R., et al. (2015) · The American Journal of Gastroenterology · doi:10.1038/ajg.2015.377 · Cited by 182
Self-citationAcharya, C., Shaw, J. A., Duong, N. K., et al. (2022) · Clinical Gastroenterology and Hepatology · doi:10.1016/j.cgh.2021.12.047 · Cited by 39
Gairing, S. J., Schleicher, E. M., Galle, P. R., & Labenz, C. (2023) · Hepatology Communications · doi:10.1097/hc9.0000000000000096 · Cited by 26
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Research works printed but not linked: 2
- Gairing, 2023, Am J Gastroenterol
- Gairing, 2023, Hepatol Commun, 7
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Sorted by citations
Management of depression/anxiety in patients with chronic liver disease
Garcia-Altieri, M., Carrera-Mejias, K., & Hernaez, R. (2024) · Clinical Liver Disease · doi:10.1097/cld.0000000000000179 · Cited by 11
Metadata
- Authors
- Kanagalingam, G., Park, D., Badal, B. D., Fagan, A., Thacker, L. R., & Bajaj, J. S.
- Affiliations
- Virginia Commonwealth University (US)
- Corresponding author
- Bajaj, Jasmohan S.
- Venue
- Clinical Gastroenterology and Hepatology
- Publisher
- Elsevier BV
- Published
- 2024-04
- Volume
- 22
- Issue
- 4
- Pages
- 899-901.e2
- ISSN
- 1542-3565 (ISSN-L)
- PMC
- PMC10960717
- OpenAlex
- W4387340085
- Cited by
- 12
- References
- 9
- Citations by year
- 2026: 5 · 2025: 3 · 2024: 3
- FWCI
- 2.03
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Clinical Gastroenterology and Hepatology (acceptedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- Funders
- US Department of Veterans Affairs (2I01CX001076)
- National Center for Advancing Translational Sciences (1I01CX002472, R21TR003095)
- NIAAA
- Topics
- Health Sciences › Medicine › Hepatology › Liver Disease and Transplantation
- Health Sciences › Medicine › Hepatology › Liver Disease Diagnosis and Treatment
- Health Sciences › Medicine › Pathology and Forensic Medicine › Alcohol Consumption and Health Effects
- Keywords
- overt hepatic encephalopathy, liver cirrhosis, covert hepatic encephalopathy, neurocognitive impairment, Stroop task, outcome prediction, hospitalization, mortality
- MeSH terms
- Hepatic Encephalopathy, Hospitalization, Humans, Liver Cirrhosis, Outpatients, Psychometrics
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