Cited by 12Liver Disease and TransplantationLiver Disease Diagnosis and TreatmentAlcohol Consumption and Health Effects

The DOI matches its Crossref record; 9 of the 9 references it cites were found in a registry or an index.

QuickStroop Predicts Time to Development of Overt Hepatic Encephalopathy and Related Hospitalizations in Patients With Cirrhosis

Open access

Abstract

Cirrhosis-related neurocognitive impairment caused by covert or minimal hepatic encephalopathy (CHE) affects psychosocial function, increases risk of overt hepatic encephalopathy (OHE) development, and worsens survival.1,2 However, detection in clinical practice is challenging.2 One modality used for screening and prediction of outcomes related to cirrhosis is the EncephalApp Stroop, but it can require up to 10 minutes. Furthermore, the assessment comprises of distinct stages of difficulty, with an easier "Off" stage and a more challenging "On" stage.3 To alleviate these concerns, QuickStroop, which takes <1 minute, was developed. This uses only the first 2 runs of the Off stage of the EncephalApp Stroop, where number signs presented in red, green, or blue need to be matched quickly to their respective colors.4 A prior study showed these versions were comparable cross-sectionally to diagnose CHE.4 However, the utility of QuickStroop to predict cirrhosis-related outcomes is unclear.5-7 Our aim was to determine the ability of QuickStroop to determine time to development of OHE and OHE-related hospitalizations, all-cause hospitalizations, and death in outpatients with cirrhosis.

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Registry

Crossref · 10.1016/j.cgh.2023.09.024

Cites

9 of 9 references verified0 citation errors · 0 not checkable

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  • QuickStroop can help predict the development of overt HE, hospitalization, and death.

    “QuickStroop, a test that takes <1 minute to apply, can help predict the development of overt HE, hospitalization, and death.13”

    From Management of depression/anxiety in patients with chronic liver disease (2024) · cites this paper as [13]

    The Abstract reports that QuickStroop takes less than one minute and that its results remained significantly associated with overt HE development and overt HE-related hospitalizations after adjustment. The discussion section beginning “However, the initial association…” says the associations with all-cause hospitalization and mortality did not persist after adjustment. Thus the unqualified claim about predicting hospitalization and death overstates the findings. (LLM, conf=0.91)

    Experimental — accuracy not yet measured

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Research works printed but not linked: 2

  1. Gairing, 2023, Am J Gastroenterol
  2. Gairing, 2023, Hepatol Commun, 7

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Metadata

Authors
Kanagalingam, G., Park, D., Badal, B. D., Fagan, A., Thacker, L. R., & Bajaj, J. S.
Affiliations
Virginia Commonwealth University (US)
Corresponding author
Bajaj, Jasmohan S.
Venue
Clinical Gastroenterology and Hepatology
Publisher
Elsevier BV
Published
2024-04
Volume
22
Issue
4
Pages
899-901.e2
ISSN
1542-3565 (ISSN-L)
OpenAlex
W4387340085
Cited by
12
References
9
Citations by year
2026: 5 · 2025: 3 · 2024: 3
FWCI
2.03
Type
journal article
Language
en
Open access
Locations
  • Clinical Gastroenterology and Hepatology (acceptedVersion)
  • PubMed (publishedVersion)
  • PubMed Central (acceptedVersion)
  • Europe PMC (PubMed Central) (acceptedVersion)
Funders
  • US Department of Veterans Affairs (2I01CX001076)
  • National Center for Advancing Translational Sciences (1I01CX002472, R21TR003095)
  • NIAAA
Topics
  • Health Sciences › Medicine › Hepatology › Liver Disease and Transplantation
  • Health Sciences › Medicine › Hepatology › Liver Disease Diagnosis and Treatment
  • Health Sciences › Medicine › Pathology and Forensic Medicine › Alcohol Consumption and Health Effects
Keywords
overt hepatic encephalopathy, liver cirrhosis, covert hepatic encephalopathy, neurocognitive impairment, Stroop task, outcome prediction, hospitalization, mortality
MeSH terms
Hepatic Encephalopathy, Hospitalization, Humans, Liver Cirrhosis, Outpatients, Psychometrics

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