Short term uptake and transport process for metformin in roots of Phragmites australis and Typha latifolia
Abstract
Metformin (MET) as an emerging contaminant has been detected in surface water and wastewater in numerous countries, due to insufficient retention in classical waste water treatment plants. In order to characterize the uptake of the compound during phytotreatment of waste water, a short term Pitman chamber experiment was carried out to assess the characteristics of MET uptake and transport by roots. Three different concentrations (0.5, 1.0 and 2.0 mmol L(-)(1)) were applied to cattail (Typha latifolia) and reed (Phragmites australis) roots which were used to investigate the uptake mechanism because they are frequently utilized in phytoremediation. In addition, quinidine was used as an inhibitor to assess the role of organic cation transporters (OCTs) in the uptake of MET by T. latifolia. The transport process of MET is different from carbamazepine (CBZ) and caffeine (CFN). In both T. latifolia and P. australis, the uptake processes were independent of initial concentrations. Quinidine, a known inhibitor of organic cation transporters, can significantly affect MET uptake by T. latifolia roots with inhibition ratios of 70-74%. Uptake into the root could be characterized by a linear model with R(2) values in the range of 0.881-0.999. Overall, the present study provides evidence that MET is taken up by plant roots and has the potential for subsequent translocation. OCTs could be one of the important pathways for MET uptake into the plant.
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Transfer through the plant has been demonstrated for many compounds.
“Transfer through the plant has been demonstrated for many compounds (Cui et al., 2015, Chen et al., 2016).”
From Intensify production, transform biomass to energy and novel goods and protect soils in Europe—A vision how to mobilize marginal lands (2018) · cites this paper as Cui et al., 2015
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- Authors
- Cui, H., Hense, B. A., Müller, J., & Schröder, P.
- Affiliations
- Helmholtz Munich (DE)
- Corresponding author
- Schröder, P.
- Venue
- Chemosphere
- Publisher
- Elsevier BV
- Published
- 2015-09
- Volume
- 134
- Pages
- 307-312
- ISSN
- 0045-6535 (ISSN-L)
- OpenAlex
- W260466185
- Cited by
- 50
- References
- 51
- Citations by year
- 2026: 2 · 2025: 3 · 2024: 5 · 2023: 4 · 2022: 6 · 2021: 8 · 2020: 3 · 2019: 3 · 2018: 7 · 2017: 7 · 2016: 2
- FWCI
- 3.30
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Chemosphere (publishedVersion)
- PubMed (publishedVersion)
- Site cant be reached (submittedVersion)
- PuSH - Publication Server of Helmholtz Zentrum München (submittedVersion)
- Topics
- Physical Sciences › Environmental Science › Pollution › Pharmaceutical and Antibiotic Environmental Impacts
- Physical Sciences › Environmental Science › Waste Management and Disposal › Constructed Wetlands for Wastewater Treatment
- Physical Sciences › Environmental Science › Environmental Chemistry › Environmental Chemistry and Analysis
- Keywords
- metformin, Phragmites australis, Typha latifolia, root uptake, root-to-shoot translocation, organic cation transporters, quinidine inhibition, phytoremediation, emerging contaminants, carbamazepine, caffeine
- MeSH terms
- Biodegradation, Environmental, Poaceae, Metformin, Soil Pollutants, Water, Plant Roots, Typhaceae
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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