Cited by 356Microbial bioremediation and biosurfactantsMicrobial Metabolic Engineering and BioproductionSteroid Chemistry and Biochemistry

Genetically engineered microorganisms for environmental remediation

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Rafeeq, Hamza, Afsheen, Nadia, Rafique, Sadia, Arshad, Arooj, Intisar, Maham, Hussain, Asim, Bilal, Muhammad, Iqbal, Hafiz M.N.·2023·Chemosphere

Abstract

In the recent era, the increasing persistence of hazardous contaminants is badly affecting the globe in many ways. Due to high environmental contamination, almost every second species on earth facing the worst issue in their survival. Advances in newer remediation approaches may help enhance bioremediation's quality, while conventional procedures have failed to remove hazardous compounds from the environment. Chemical and physical waste cleanup approaches have been used in current circumstances; however, these methods are costly and harmful to the environment. Thus, there has been a rise in the use of bioremediation due to an increase in environmental contamination, which led to the development of genetically engineered microbes (GEMs). It is safer and more cost-effective to use engineered microorganisms rather than alternative methods. GEMs are created by introducing a stronger protein into bacteria through biotechnology or genetic engineering to enhance the desired trait. Biodegradation of oil spills, halobenzoates naphthalenes, toluenes, trichloroethylene, octanes, xylenes etc. has been accomplished using GEMs such bacteria, fungus, and algae. Biotechnologically induced microorganisms are more powerful than naturally occurring ones and may degrade contaminants faster because they can quickly adapt to new pollutants they encounter or co-metabolize. Genetic engineering is a worthy process that will benefit the environment and ultimately the health of our people.

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  • Top-down engineering focuses on self-assembling microbial consortia without taking species specificity or metabolic pathways into account.

    “Still, top-down engineering focuses on self-assembling microbial consortia without taking species specificity or metabolic pathways into account [293].”

    From Harnessing bacterial consortia for effective bioremediation: targeted removal of heavy metals, hydrocarbons, and persistent pollutants (2025) · cites this paper as [293]

    Section 3 discusses engineered microbial communities, including functionally specialized species and metabolically driven interactions, but does not describe a top-down approach or say that it disregards species specificity or metabolic pathways. Searches for “top-down,” “self-assembling,” and those specific qualifications found no passage addressing the claimed distinction; page numbers were not available in our copy. (LLM, conf=0.74)

    Experimental — accuracy not yet measured
  • Bacterial communities compete for scarce nutrients and utilize metabolic byproducts excreted by other species to enhance their fitness.

    “Communities of bacteria exhibit competition for scarce nutrients and utilize metabolic byproducts excreted by other species to enhance their fitness [293].”

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Authors
Rafeeq, H., Afsheen, N., Rafique, S., Arshad, A., Intisar, M., Hussain, A., Bilal, M., & Iqbal, H. M. N.
Affiliations
  • Riphah International University (PK)
  • University of Agriculture Faisalabad (PK)
  • Poznań University of Technology (PL)
  • Tecnológico de Monterrey (MX)
Corresponding author
  • Bilal, Muhammad
  • Iqbal, Hafiz M.N.
Venue
Chemosphere
Publisher
Elsevier BV
Published
2023-01
Volume
310
Pages
136751
ISSN
0045-6535 (ISSN-L)
OpenAlex
W4302759864
Cited by
356
References
1
Citations by year
2026: 107 · 2025: 111 · 2024: 111 · 2023: 24 · 2022: 3
FWCI
14.62
Type
journal article
Language
en
Open access
Locations
  • Chemosphere (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • Greater South Information System
Funders
  • Consejo Nacional de Ciencia y Tecnología
  • Narodowe Centrum Nauki (2020/37/K/ST8/03805)
  • Sistema Nacional de Investigadores (735340)
Topics
  • Physical Sciences › Environmental Science › Pollution › Microbial bioremediation and biosurfactants
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Microbial Metabolic Engineering and Bioproduction
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Steroid Chemistry and Biochemistry
Keywords
genetically modified microorganisms, bioremediation, environmental remediation, hazardous contaminants, biodegradation, oil spill bioremediation, naphthalene, toluene, trichloroethylene, octane, xylene, cometabolism, bacteria, fungi, algae
MeSH terms
Bacteria, Biodegradation, Environmental, Environmental Pollutants, Genetic Engineering, Humans, Environmental Restoration and Remediation

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

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