The DOI matches its Crossref record; 99 of the 99 references it cites were found in a registry or an index.
Microbes, Microbiota, and Colon Cancer
Open accessAbstract
Summary Colorectal cancer (CRC) presents a considerable disease burden worldwide. The human colon is also an anatomical location with the largest number of microbes. It is natural therefore to anticipate a role for microbes, particularly bacteria, in colorectal carcinogenesis. The increasing accessibility of microbial meta’omics is fueling a surge in our understanding of the role that microbes and the microbiota play in CRC. In this review, we will discuss recent insights into contributions of the microbiota to CRC and explore conceptual frameworks for evaluating the role of microbes in cancer causation. We also highlight new findings on candidate CRC-potentiating species and current knowledge gaps. Finally, we explore the roles of microbial metabolism as it relates to bile acids, xenobiotics, and diet in the etiology and therapeutics of CRC.
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Cites
Diet rapidly and reproducibly alters the human gut microbiome
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Cited by
Hallmarks of Cancer: New Dimensions
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Bile acid-microbiota crosstalk in gastrointestinal inflammation and carcinogenesis
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Garrett, W. S. (2015) · Science · doi:10.1126/science.aaa4972 · Cited by 1,404
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Metadata
- Authors
- Sears, C. L., & Garrett, W. S.
- Venue
- Cell Host & Microbe
- Publisher
- Elsevier BV
- Published
- 2014-03
- Volume
- 15
- Issue
- 3
- Pages
- 317-328
- ISSN
- 1931-3128 (ISSN-L)
- OpenAlex
- W2161548174
- Cited by
- 818
- References
- 99
- FWCI
- 25.19
- Type
- journal article
- Language
- en
- Open access
- bronze
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
