Both Neutralizing and Non-Neutralizing Human H7N9 Influenza Vaccine-Induced Monoclonal Antibodies Confer Protection
Henry Dunand, Carole J., Leon, Paul E., Huang, Min, Choi, Angela, Chromikova, Veronika, Ho, Irvin Y., Tan, Gene S., Cruz, John +11 more·2016·Cell Host & Microbe
Cited by (270)
Items 201–270 of 270
- Identification of the dominant non-neutralizing epitope in the haemagglutinin of H7N9 avian influenza virusZenglei Hu, Jiangyan Zhao, Lei Shi, Jiao Hu, Xiaoquan Wang, Xiufan Liu, Shunlin Hu, Min Gu, Xiufan Liu · 2021 · Virus Research
- One HA stalk topping multiple heads as a novel influenza vaccinePing Zhou, Tianyi Qiu, Xiang Wang, Xi Yang, Hongyang Shi, Caihong Zhu, Weiqian Dai, Man Xing, Xiaoyan Zhang, Jianqing Xu et al. · 2023 · Emerging Microbes & Infections
- Fc-mediated functions and the treatment of severe respiratory viral infections with passive immunotherapy – a balancing actHillary A. Vanderven, Stephen John Kent · 2023 · Frontiers in Immunology
- Molecular parameters governing antibody FcγR signaling and effector functions in the context of HIV envelopeMichael Bick, Eduard Puig, David Beauparlant, Rebecca Nedellec, Iszac Burton, Keihvan Ardaghi, Thea R. Zalunardo, Raiza B. Bastidas, Xuduo Li, Javier Guenaga et al. · 2025 · Cell Reports
- Stereotyped B-cell response that counteracts antigenic variation of influenza virusesKeisuke Tonouchi, Yu Adachi, Saya Moriyama, Kaori Sano, Koshiro Tabata, Keigo Ide, Haruko Takeyama, Tadaki Suzuki, Yoshimasa Takahashi · 2020 · International Immunology
- Influenza Vaccination Results in Differential Hemagglutinin Stalk-Specific Fc-Mediated Functions in Individuals Living With or Without HIVBoitumelo M. Motsoeneng, Nisha Dhar, Marta Coelho Nunes, Florian Krammer, Shabir Ahmed Madhi, Penny L. Moore, Simone I. Richardson · 2022 · Frontiers in Immunology
- Post-fusion influenza vaccine adjuvanted with SA-2 confers heterologous protection via Th1-polarized, non-neutralizing antibody responsesAyae Nishiyama, Yu Adachi, Keisuke Tonouchi, Saya Moriyama, Lin Sun, Masamitsu Aoki, Hideki Asanuma, Masayuki Shirakura, Akihisa Fukushima, Takuya Yamamoto et al. · 2023 · Vaccine
- A Method to Assess Fc-mediated Effector Functions Induced by Influenza Hemagglutinin Specific AntibodiesMark J. Bailey, Felix Broecker, Paul E. Leon, Gene S. Tan · 2018 · Journal of Visualized Experiments
- Development of a high-throughput assay to detect antibody inhibition of low pH induced conformational changes of influenza virus hemagglutininJessica F. Trost, Elizabeth H. LeMasters, Feng Liu, Paul J. Carney, Xiuhua Lu, Kanetsu Sugawara, Seiji Hongō, James Stevens, David A. Steinhauer, Terrence M. Tumpey et al. · 2018 · PLoS ONE
- Development and biochemical characterization of the monoclonal antibodies for specific detection of the emerging H5N8 and H5Nx avian influenza virus hemagglutininsYu‐Chen Cheng, Shih‐Chung Chang · 2020 · Applied Microbiology and Biotechnology
- The parasite-derived rOv-ASP-1 is an effective antigen-sparing CD4 + T cell-dependent adjuvant for the trivalent inactivated influenza vaccine, and functions in the absence of MyD88 pathwaySonia Jain, Parakkal Jovvian George, Wanyan Deng, Joseph Koussa, Kaela Parkhouse, Scott E. Hensley, Jiu Kun Jiang, Jie Li Lu, Zhuyun Liu, Junfei Wei et al. · 2018 · Vaccine
- Single-cell sequencing of plasma cells from COVID-19 patients reveals highly expanded clonal lineages produce specific and neutralizing antibodies to SARS-CoV-2Roy A. Ehling, Cédric R. Weber, Derek M. Mason, Simon Friedensohn, Bastian Wagner, Florian Bieberich, Edo Kapetanovic, Rodrigo Vazquez-Lombardi, Raphaël B. Di Roberto, Kai-Lin Hong et al. · 2021 · bioRxiv
- Mapping antibody footprints using binding profilesAsaf Azulay, Liel Cohen-Lavi, Lilach M. Friedman, Maureen Ann McGargill, Tomer Hertz · 2023 · Cell Reports Methods
- Protective Non-neutralizing anti–N-terminal Domain mAb Maintains Fc-mediated Function against SARS-COV-2 Variants up to BA.2.86-JN.1 with Superfluous In Vivo Protection against JN.1 Due to Attenuated VirulenceArman Izadi, Magdalena Godzwon, Anna Söderlund‐Strand, Tobias Schmidt, Susanna Kumlien Georén, Christian Drosten, Mats Ohlin, Pontus Nordenfelt · 2024 · The Journal of Immunology
- Live Attenuated Influenza Vaccines for Pandemic PreparednessKanta Subbarao · 2019 · Journal of the Pediatric Infectious Diseases Society
- Evaluation of strategies to modify Anti-SARS-CoV-2 monoclonal antibodies for optimal functionality as therapeuticsRobert V. House, Thomas A. Broge, Todd J. Suscovich, Doris M. Snow, Milan T. Tomic, Genevieve H. Nonet, Kamaljit Bajwa, Guangyu Zhu, Zachary Martinez, Kyal Hackett et al. · 2022 · PLoS ONE
- Highly pathogenic avian influenza A/Guangdong/17SF003/2016 is immunogenic and induces cross-protection against antigenically divergent H7N9 virusesPeter Radvák, Martina Košíková, Charles Yuan-Chia Kuo, Xing Li, Richard Garner, Falko Schmeisser, Ivan Košík, Zhiping Ye, Jerry P. Weir, Jonathan Wilson Yewdell et al. · 2021 · npj Vaccines
- Fc effector functions in RNA viral infections: mechanisms of antiviral immunity and implications for vaccine designJiale Zhang, Chuang Li, Yuanyuan Wu, Lili Wang, Jie Yu, Aofan Wang, Wenwen Kong, Mingzhe Ning, J M Chen, Yuxin Chen · 2026 · Frontiers in Immunology
- Characterization of antibody‐dependent cellular phagocytosis in patients infected with hepatitis C virus with different clinical outcomesAnurag Adhikari, Arunasingam Abayasingam, Nicholas A. Brasher, Ha Na Kim, Megan Susan Lord, David Agapiou, Lisa Maher, Chaturaka Rodrigo, Andrew R. Lloyd, Rowena Anne Bull et al. · 2024 · Journal of Medical Virology
- Polyfunctionality and breadth of HIV-1 antibodies are associated with delayed disease progressionMarloes Grobben, Margreet E. Bakker, Angela I. Schriek, Liesbeth J.J. Levels, Jeffrey C. Umotoy, Khadija Tejjani, Mariëlle J. van Breemen, Ryan N. Lin, Steven W. de Taeye, Gabriel Ozorowski et al. · 2024 · PLoS Pathogens
- Self-assembly polymerization enhances the immunogenicity of influenza M2e peptidePeng Zou, Yuan Li, Jinghe Huang, Fan Wu · 2017 · Microbes and Infection
- Isolation of an in Vitro Affinity-Matured, Thermostable “Headless” HA Stem Fragment That Binds Broadly Neutralizing Antibodies with High AffinityTariq Ahmad Najar, Uddipan Kar, Jessica A. Flynn, Raghavan Varadarajan · 2018 · Biochemistry
- Exploring the global immune landscape of peripheral blood mononuclear cells in H5N6-infected patient with single-cell transcriptomicsJiamin Gao, Jing Wei, Simei Qin, Sheng Liu, Shuangyan Mo, Long Qian, Shiji Tan, Ning Lu, Zhouhua Xie, Jianyan Lin · 2023 · BMC Medical Genomics
- Broad neutralizing activity of a human monoclonal antibody against H7N9 strains from 2013 to 2017Cong Chen, Zuliang Liu, Liguo Liu, Yan Xiao, Jianmin Wang, Qi Jin · 2018 · Emerging Microbes & Infections
- Antibody-dependent cell-mediated cytotoxicity antibody responses to inactivated and live-attenuated influenza vaccination in children during 2014–15Kelsey R. Florek, James P. Mutschler, Huong Q. McLean, Jennifer P. King, Brendan L. Flannery, Edward A. Belongia, Thomas C. Friedrich · 2019 · Vaccine
- A public broadly neutralizing antibody class targets a membrane-proximal anchor epitope of influenza virus hemagglutininJenna J. Guthmiller, Julianna Han, Henry A. Utset, Lei Li, Linda Yu-Ling Lan, Carole Henry, Christopher T. Stamper, Olivia Stovicek, Lauren E. Gentles, Haley L. Dugan et al. · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
- A single-dose intranasal immunization with a novel bat influenza A virus-vectored MERS vaccine provides effective protection against lethal MERS-CoV challengeLei Shi, Sawrab Roy, Yuekun Lang, Yuhan Wen, William J. Mitchell, Wenyu Yang, Liping Wang, Jialin Zhang, Heidi Liu, John P. Driver et al. · 2025 · mBio
- Cross-Reactive Fc-Mediated Antibody Responses to Influenza HA Stem Region in Human Sera Following Seasonal VaccinationAyae Nishiyama, Takuto Nogimori, Yuji Masuta, Tomoka Matsuura, Tetsuo Kase, Kyoko Kondo, Satoko Ohfuji, Yu Nakagama, Natsuko Kaku, Sachie Nakagama et al. · 2025 · Vaccines
- Global Prevalence and Hemagglutinin Evolution of H7N9 Avian Influenza Viruses from 2013 to 2022Qianshuo Liu, Haowen Zeng, Xinghui Wu, Xuelian Yang, Guiqin Wang · 2023 · Viruses
- Narrative review of the novel coronavirus SARS-CoV-2: update on genomic characteristics, transmissions and animal modelZhao-Yong Zhang, Lu Zhang, Ai-Ru Zhu, Yan-Qun Wang, Wen-Da Guan, Zhi-Qi Zeng, Jing Sun, Fang Li, Jing-Xian Zhao, Zi-Feng Yang et al. · 2020 · Journal of Thoracic Disease
- Cross-reactive single-domain antibodies to hemagglutinin stem region protect mice from group 1 influenza A virus infectionDaria V. Voronina, Банделюк Алина Сергеевна, Alina Sh. Dzharullaeva, Olga D. Popova, Vladislav Y. Kan, Ilias B. Esmagambetov, Irina A. Favorskaya, Dmitry V. Shcheblyakov, Boris Savelyevich Naroditskiy, Gintsburg Al · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
- Antibodies elicited by Newcastle disease virus-vectored H7N9 avian influenza vaccine are functional in activating the complement systemZenglei Hu, Ya Huang, Jiao Hu, Xiaoquan Wang, Shunlin Hu, Xiufan Liu · 2023 · Journal of Integrative Agriculture
- High-complexity extracellular barcoding using a viral hemagglutininGavriel Mullokandov, Gayathri Vijayakumar, Paul E. Leon, Carole Henry, Patrick C. Wilson, Florian Krammer, Peter Palese, Brian D. Brown · 2020 · Proceedings of the National Academy of Sciences
- Switching Heavy Chain Constant Domains Denatures the Paratope 3D Architecture of Influenza Monoclonal AntibodiesMoffat M. Malisheni, Cheng‐Shoong Chong, Tanusya Murali Murali, Kiren Purushotorman, Xinlei Qian, Alfred Laiman, Yee‐Joo Tan, Paul A. MacAry · 2022 · Pathogens
- Site‐specific serology unveils cross‐reactive monoclonal antibodies targeting influenza A hemagglutinin epitopesPhilipp Paparoditis, Alexander Fruehwirth, Kajetana Bevc, Jun Siong Low, Josipa Jerak, Laura Terzaghi, Mathilde Foglierini, Blanca Fernandez, David Jarrossay, Davide Corti et al. · 2024 · European Journal of Immunology
- Single and 2-dose vaccinations with MVA-BN ® induce durable B cell memory responses in healthy volunteers that are comparable to older generation replicating smallpox vaccinesHeiko Ilchmann, Nathaly Samy, Daniela Reichhardt, Darja Schmidt, Jacqueline D Powell, Thomas P.H. Meyer, Günter Silbernagl, Rick Nichols, Heinz Weidenthaler, Laurence De Moerlooze et al. · 2022 · medRxiv
- Mumps VaccinesSteven A. Rubin · 2023 · Elsevier eBooks
- Protective Efficacy of an Inactivated Recombinant Serotype 4 Fowl Adenovirus Against Duck Adenovirus 3 in Muscovy DuckYun Lin, Wenjie Jiang, Lihua Ma, Jiayu Zhang, Ye Tang, Qiuqi Kan, Haifeng Xiong, Jiayan Wu, Jun Zhang, Yiwen Niu et al. · 2024 · Vaccines
- Structural basis for a potent human neutralizing antibody targeting a conserved epitope on the H7 hemagglutinin headJunxin Li, Min Wang, Yang Yang, Limin Zhang, Lvyan Liu, Wei Zhong Yang, Yun Peng, Xu Zhang, Bin Yuan, Qi Peng et al. · 2025 · Proceedings of the National Academy of Sciences
- Direct airway delivery of a humanized anti-H7N9 neutralizing antibody broadly protects against divergent H7 influenza viruses in the mouse modelYu Wang, Xiaozheng He, Jiangyan Zhao, Yunlong Dou, Tingyu Hu, Xia Chen, Xiangrui Ma, Xiaoquan Wang, Shunlin Hu, Jiao Hu et al. · 2025 · Journal of Virology
- Structural and functional characterization of the antigenicity of influenza A virus hemagglutinin subtype H15Disha Bhavsar, André Nicolás León, Wei‐Li Hsu, Eduard Puente‐Massaguer, James A. Ferguson, Julianna Han, Patrick C. Wilson, Andrew B. Ward, Florian Krammer · 2026 · Cell Reports
- Counteracting Influenza Virus Evolution Through the Full Spectrum of Broadly Protective AntibodiesYu Adachi, Yoshimasa Takahashi · 2026 · Immunological Reviews
- Monoclonal antibodies for diagnostic and therapeutic systems to combat microbial infectionsParsa Pishva, Irmak C. Kayalan, Fatma Sert, Meral Yüce · 2022 · Elsevier eBooks
- Coronavirus nucleocapsid-based vaccine provides partial protection against hetero-species coronavirus in murine modelsPureum Lee, Jihee Kim, Hanseul Oh, Chang-Ung Kim, Ahn Young Jeong, Moo‐Seung Lee, Min Seong Jang, Jung Joo Hong, Jung-Eun Park, Doo‐Jin Kim · 2024 · Antiviral Research
- Converting non-neutralizing SARS-CoV-2 antibodies targeting conserved epitopes into broad-spectrum inhibitors through receptor blockadePayton A. B. Weidenbacher, Eric Waltari, Izumi de los Rios Kobara, Benjamin N. Bell, John E. Pak, Peter S. Kim · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
- Protective non-neutralizing mAbs Ab94 and Ab81 retain high-affinity and potent Fc-mediated function against SARS-CoV-2 variants from Omicron to XBB1.5Arman Izadi, Magdalena Godzwon, Mats Ohlin, Pontus Nordenfelt · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
- Estudo do efeito adjuvante do peptídeo derivado da proteína NS3 na resposta imunológica de camundongos vacinados com vírus Zika inativadoJonathan Ballico de Moraes · 2019
- The Zika virus NS1 protein as a vaccine targetMark J. Bailey, Gene S. Tan · 2021 · Elsevier eBooks
- Machupo virus with mutations in the transmembrane domain and glycosylation sites is attenuated and immunogenic in animal models of Bolivian Hemorrhagic FeverEmily Mantlo, Junki Maruyama, John T Manning, Timothy G. Wanninger, Cheng Huang, Jeanon N. Smith, Michael Patterson, Slobodan Paessler, Takaaki Koma · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
- Faculty Opinions recommendation of Influenza Infection in Humans Induces Broadly Cross-Reactive and Protective Neuraminidase-Reactive Antibodies.Nicholas S. Heaton · 2018 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
- Influenza Virus and VaccinationMarta L. DeDiego, Aitor Nogales · 2020 · MDPI eBooks
- Faculty Opinions recommendation of Antibiotics-Driven Gut Microbiome Perturbation Alters Immunity to Vaccines in Humans.Graham Pawelec · 2020 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
- Identification of genetic and antigenic variation and evolution pattern among influenza a and b viruses in ThailandNungruthai Suntronwong · 2020
- Human cross-protective antibodies to occluded epitopes in influenza hemagglutinin antigenYu Adachi, Keisuke Tonouchi, Yoshimasa Takahashi · 2019 · Uirusu
- Monoglycosylated SARS-CoV-2 receptor binding domain fused with HAstem-scaffolded protein vaccine confers broad protective immunity against SARS-CoV-2 and influenza virusesChia-Ying Wu, Yung-Chieh Tseng, Shao-En Kao, Liyang Wu, Jen-Tzu Hou, Yu‐Chih Yang, Pei‐Wen Hsiao, Juine-Ruey Chen · 2023 · Antiviral Research
- Development and validation of a high throughput multiplex immunofluorescence assay to detect all human immunoglobulin isotypes and subclasses in human fluidsArthur H. van Stigt, Maaike Nederend, Gaby P. Smits, Marjan Kuijer, Rutger M. Schepp, Pieter G. M. van Gageldonk, Anneke H. Hellinga, Rob S. van Binnendijk, Louis Bont, Belinda van’t Land et al. · 2025 · The Journal of Immunology
- Subtype-specific neutralizing antibodies promote antigenic shift during influenza virus co-infectionMengnan Liu, Xiaoran Gao, Xueyang Li, Jinyang Hao, Christine M. Light, Yu Tian, Siqin Wang, Wenyu Yan, Rong Hai, Wei Hu et al. · 2026 · Virulence
- Structure basis for distinct protective mechanisms of IGHV3-23 antibodies targeting influenza hemagglutinin stemHuibin Lv, Yang Wei Huan, Tossapol Pholcharee, Qi Wen Teo, Wenkan Liu, Akshita Baiju Gopal, Danbi Choi, Madison R. Ardagh, Timothy J.C. Tan, Yuanxin Sun et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
- Additional file 2 of Exploring the global immune landscape of peripheral blood mononuclear cells in H5N6-infected patient with single-cell transcriptomicsGao, Jiamin, Wei, Jing, Simei Qin, Liu, Sheng, Shuangyan Mo, Long, Qian, Shiji Tan, Lu, Ning, Xie, Zhouhua, Lin, Jianyan · 2024 · Figshare
- Additional file 1 of Exploring the global immune landscape of peripheral blood mononuclear cells in H5N6-infected patient with single-cell transcriptomicsGao, Jiamin, Wei, Jing, Simei Qin, Liu, Sheng, Shuangyan Mo, Long, Qian, Shiji Tan, Lu, Ning, Xie, Zhouhua, Lin, Jianyan · 2023 · Figshare
- DNA vaccines targeting hemagglutinin from 18 subtypes of influenza A virus to antigen-presenting cells confer broad protectionAne Marie Anderson, Elias Tjärnhage, Daniëla Maria Hinke, Ranveig Braathen, Gunnveig Grødeland, Bjarne Bogen · 2025 · Molecular Therapy — Nucleic Acids
- Evaluating varicella-zoster virus vaccine immunogenicity through Fc-mediated antibody functions: the roles of ADCP and ADCCSivilay Xayaheuang, Ji‐Young Hwang, Yunhwa Kim, Kyung-Min Lee, Seok-Tae Choi, Eun-Jeong Jang, Ji-Soo Lim, Ji Young Bang, Han Sol Lee, Ok Sarah Shin et al. · 2026 · npj Vaccines
- Caractérisation des activités antivirales des anticorps anti-VIH-1 et anti-SARS-CoV-2Jérémy Dufloo · 2021 · theses.fr (ABES)
- Fc-engineered antibodies enhance protection against SARS-CoV-2 lung infection and inflammationSamantha Mackin, Chieh-Yu Liang, Courtney E. Karl, Maksim Kleverov, Mehak Zahoor Khan, Thendral Selvam, Matthias Mack, Galit Alter, Barbara Guarino, Davide Corti et al. · 2026 · mBio
- Subclass switching enhances protective efficacy of a non-neutralizing H7N9 avian influenza antibodyYunlong Dou, Jiangyan Zhao, Xiaozheng He, Seung-un Song, Erdene-Ochir Tseren-Ochir, Chang‐Seon Song, Xiufan Liu, Jiao Hu, Zenglei Hu · 2026 · Veterinary Microbiology
- Neutralizing and protective monoclonal antibodies identify antigenic sites in influenza H7 hemagglutinin and select for amino acid substitutions rarely observed at the global levelGabriel Ignacio Parra, Marcus Odin, Kentaro Tohma, Falko Schmeisser, Clement A. Meseda, Wei Wang, Carol D. Weiss, Russell A. Vassell, Amy M. Woerner, Cyntia L. Pedro et al. · 2026 · Microbiology Spectrum
- A bispecific antibody targeting conserved hemagglutinin epitopes confers broad protection against H7 avian influenza and accelerates viral clearance via localized respiratory deliveryHan Wu, Fan Yang, Ping Wang, Jiamin Fu, Jun Zhang, Jing Guo, 程林芳, Fumin Liu, 吴南屏, Hangping Yao et al. · 2026 · Emerging Microbes & Infections
- Chronic chikungunya is associated with decreased anti-CHIKV antibody titers, neutralizing capacity, and antibody-dependent cellular cytotoxicityVinit Upasani, Sokchea Lay, Sievleang Heng, Alvino Maestri, Sreymom Ken, Sopheak Sorn, Rithea Leang, Sowath Ly, Veasna Duong, Tineke Cantaert · 2026 · iScience
- Antibodies elicited in humans upon chimeric hemagglutinin-based influenza virus vaccination confer FcgR-dependent protection in vivoJeffrey Ravetch · 2024 · ImmPort
- Responses to Inactivated Influenza Vaccine (IIV) in adults with or without antibioticsNadine Rouphael, M Mulligan, Aneesh Mehta, Srilatha Edugupanti, Colleen Kelley, Sarah Kabbani, Allison Beck · 2019 · ImmPort