The DOI matches its Crossref record; 69 of the 69 references it cites were found in a registry or an index.
Ten Strategies of Interferon Evasion by Viruses
Open accessAbstract
Viruses infecting vertebrate hosts must overcome the interferon (IFN)-mediated antiviral response to replicate and propagate to new hosts. The complex regulation of the IFN response allows viruses to antagonize IFN at multiple levels. However, no single strategy appears to be the golden ticket, and viruses have adopted multiple means to dampen this host defense. This review does not exhaustively cover all mechanisms of viral IFN antagonism. Rather it examines the ten most common strategies that viruses use to subvert the IFN response with examples from publications appearing in the last 10 years of Cell Host & Microbe. The virus-host interactions involved in induction and evasion of IFN represent a fertile area of research due to the significant large number of host and viral products that regulate this response, resulting in an intricate dance between hosts and their pathogens to achieve an optimal balance between virus replication, host disease and survival.
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Cited by
Imbalanced Host Response to SARS-CoV-2 Drives Development of COVID-19
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Shared and Distinct Functions of Type I and Type III Interferons
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Decoding type I and III interferon signalling during viral infection
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Tailoring mRNA Vaccine to Balance Innate/Adaptive Immune Response
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Metadata
- Authors
- García-Sastre, A.
- Venue
- Cell Host & Microbe
- Publisher
- Elsevier BV
- Published
- 2017-08
- Volume
- 22
- Issue
- 2
- Pages
- 176-184
- ISSN
- 1931-3128 (ISSN-L)
- OpenAlex
- W2742305663
- Cited by
- 423
- References
- 69
- FWCI
- 13.50
- Type
- journal article
- Language
- en
- Open access
- bronze
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