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Recent advances in tannic acid-based gels: Design, properties, and applications
Abstract
With the flourishing of mussel-inspired chemistry, the fast-growing development for environmentally friendly materials, and the need for inexpensive and biocompatible analogues to PDA in gel design, TA has led to its gradual emergence as a research focus due to its remarkable biocompatible, renewable, sustainable and particular physicochemical properties. As a natural building block, TA can be used as a substrate or crosslinker, ensuring versatile functional polymeric networks for various applications. In this review, the design of TA-based gels is summarized in detail (i.e., different interactions such as: metal coordination, electrostatic, hydrophobic, host-guest, cation-π and π-π stacking interactions, hydrogen bonding and various reactions including: phenol-amine Michael and Schiff base, phenol-thiol Michael addition, phenol-epoxy ring opening reaction, etc.). Subsequently, TA-based gels with a variety of functionalities, including mechanical, adhesion, conductive, self-healing, UV-shielding, anti-swelling, anti-freezing, shape memory, antioxidant, antibacterial, anti-inflammatory and responsive properties are introduced in detail. Then, a summary of recent developments in the use of TA-based gels is provided, including bioelectronics, biomedicine, energy, packaging, water treatment and other fields. Finally, the difficulties that TA-based gels are currently facing are outlined, and an original yet realistic viewpoint is provided in an effort to spur future development.
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“Additionally, quinone structures are capable of undergoing Michael addition reactions with protein thiols or amino groups, thereby enhancing the integration between the coating and the surrounding tissue48.”
From Intelligence-responsive wettability switch coating on magnesium implants for treating osteoporotic fracture (2026) · cites this paper as [48]
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Chen, L., Sun, J., Wei, H., Lei, H., Chen, T., Zhang, J., Feng, G., Wang, J., Zhang, Y., Wang, Y., et al. (2023) · SSRN Electronic Journal · doi:10.2139/ssrn.4379226 · Cited by 2
Hu, X., Yan, L., & Zhang, M. (2024) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2024.135881 · Cited by 1
Flagged first, then by citations
4 of the 509 references couldn’t be matched to a known paper.
Cited by
Sorted by citations
Deng, J., Wang, H., Huang, J., Hu, J., Pan, Z., Gao, R., Wang, L., & Xu, D. S. (2025) · Journal of Environmental Management · doi:10.1016/j.jenvman.2025.126266 · Cited by 32
Liu, H., Chen, X., Chen, D., Zhang, Z., Xia, Y., Zhang, K., Ming, J., & Lei, X. (2025) · Food Chemistry · doi:10.1016/j.foodchem.2025.144935 · Cited by 22
A review on cellulose-based derivatives and composites for sustainable rechargeable batteries
Farooq, A., Wanyan, H., Lu, S., Mosisa, M. T., Zhou, X., Xiao, H., Liu, K., Huang, L., Chen, L., & Wu, H. (2025) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2025.142528 · Cited by 21
Self-citationRecent advances in eutectogels: Preparation, properties and applications
Wang, J., Zhen, Y., Hao, J., & Chai, C. (2025) · Advances in Colloid and Interface Science · doi:10.1016/j.cis.2025.103659 · Cited by 19
Li, X., He, X., Zhou, M., Yu, Z., Zheng, Q., Gan, H., Wang, Y., Jiang, Q., He, H., & Yu, Z. (2026) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2026.125395 · Cited by 18
Metadata
- Authors
- Tang, Z., Chowdhury, I. F., Yang, J., Li, S., Mondal, A. K., & Wu, H.
- Affiliations
- Fujian Polytechnic Normal University (CN)
- Bangladesh Council of Scientific and Industrial Research (BD)
- Fujian Agriculture and Forestry University (CN)
- Corresponding author
- Mondal, Ajoy Kanti
- Wu, Hui
- Venue
- Advances in Colloid and Interface Science
- Publisher
- Elsevier BV
- Published
- 2025-05
- Volume
- 339
- Pages
- 103425
- ISSN
- 0001-8686 (ISSN-L)
- OpenAlex
- W4407596944
- Cited by
- 70
- References
- 509
- Citations by year
- 2026: 38 · 2025: 32
- FWCI
- 4.49
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- Locations
- Advances in Colloid and Interface Science (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Natural Science Foundation of China
- Topics
- Physical Sciences › Materials Science › Biomaterials › Hydrogels: synthesis, properties, applications
- Physical Sciences › Materials Science › Biomaterials › Supramolecular Self-Assembly in Materials
- Physical Sciences › Materials Science › Surfaces, Coatings and Films › Polymer Surface Interaction Studies
- Keywords
- tannic acid, mussel-inspired chemistry, crosslinking, metal coordination, host-guest interactions, cation-π interactions, π-π stacking, hydrogen bonding, Schiff base, Michael addition, self-healing gels, shape memory effect, conductive gels, antibacterial gel, anti-inflammatory gel, responsive gels, bioelectronics, water treatment, packaging, energy materials, biomedicine
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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